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Mon, 07 Mar 2011 at 22:38:11


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Breast Cancer - news item 1 of 119
Determining benign/malignant breast tumors
TROY, N.Y., March 5 (UPI) -- A U.S. doctoral student says his computational research may result in a faster way to differentiate between benign and malignant breast cancer tumors. (Source: Health News - UPI.com)
RSS Source:   Med Worm - Breast Cancer Sat, 5 Mar 2011 8:01:30 pm
Breast Cancer - news item 2 of 119
Primary tumor dependent inhibition of tumor growth, Angioâ€Genesis, and perfusion of secondary breast cancer in bone
AbstractThe systemic balance of angiogenic and antiâ€angiogenic factors has been proposed to play a keyâ€role in primary tumor growth dependent growth suppression of secondary tumors. Despite the importance of the organ microenvironment to angiogenesis and microcirculation, the influence of a primary tumor on secondary bone tumors has not been investigated...
RSS Source:   Med Worm - Breast Cancer Sat, 5 Mar 2011 7:17:22 pm
Breast Cancer - news item 3 of 119
Dietary Intake, Supplement Use, and Survival Among Women Diagnosed With Early-Stage Breast Cancer
(Source: Nutrition and Cancer)
RSS Source:   Med Worm - Breast Cancer Sat, 5 Mar 2011 2:37:59 pm
Breast Cancer - news item 4 of 119
Prostate cancer: Targeted therapy shrank tumors up to 74 percent in cells in mice
Researchers have identified a potential target to treat an aggressive type of prostate cancer. The target, a gene called SPINK1, could be to prostate cancer what HER2 has become for breast cancer. (Source: ScienceDaily Headlines)
RSS Source:   Med Worm - Breast Cancer Sat, 5 Mar 2011 12:00:00 pm
Breast Cancer - news item 5 of 119
Hologic Showcases Its 3D Mammography (Breast Tomosynthesis) At National Consortium Of Breast Centers (NCBC) Meeting
Hologic, Inc. (Hologic or the Company) (Nasdaq: HOLX), a leading developer, manufacturer and supplier of premium diagnostics products, medical imaging systems and surgical products dedicated to serving the healthcare needs of women, will showcase its 3D mammography and other new, ready-to-market technologies in women's imaging at the 21st Annual National...
RSS Source:   Med Worm - Breast Cancer Sat, 5 Mar 2011 9:00:00 am
Breast Cancer - news item 6 of 119
The Lancet Publishes Results From Pivotal Study Of Eisai's Halaven® In Patients With Late-Stage Metastatic Breast Cancer
Eisai Co., Ltd. (Headquarters: Tokyo, President & CEO: Haruo Naito) announced that results from a pivotal study with HALAVEN® (eribulin mesylate), a novel anticancer agent discovered and developed by the company, will be published in the medical journal The Lancet1). The study being published is the global phase III clinical...
RSS Source:   Med Worm - Breast Cancer Sat, 5 Mar 2011 8:00:00 am
Breast Cancer - news item 7 of 119
Less Expensive, More Effective, And Safer Diagnosis Of Breast Cancer
Recent research by doctoral student Sevan Goenezen holds the promise of becoming a powerful new weapon in the fight against breast cancer. His complex computational research has led to a fast, inexpensive new method for using ultrasound and advanced algorithms to differentiate between benign and malignant tumors with a high...
RSS Source:   Med Worm - Breast Cancer Sat, 5 Mar 2011 7:00:00 am
Breast Cancer - news item 8 of 119
Chemo May Raise Risk of Falls in Breast Cancer Survivors
Changes in system that regulates balance may be to blame, researchers suggest (Source: Cancercompass News: Breast Cancer)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 11:00:00 pm
Breast Cancer - news item 9 of 119
Chemotherapy for Breast Cancer May Raise Risk of Falls
Breast cancer treatments such as chemotherapy and hormonal therapy may affect the patients’ balance, increasing their risk of falls, a new study shows. (Source: WebMD Health)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 7:31:45 pm
Breast Cancer - news item 10 of 119
Double-Transduced MDCKII Cells To Study Human P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) Interplay in Drug Transport across the Bloodâˆ'Brain Barrier
Molecular PharmaceuticsDOI: 10.1021/mp1003898 (Source: Molecular Pharmaceutics) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 7:24:43 pm
Breast Cancer - news item 11 of 119
Smoking Linked to Breast Cancer in Older Women (CME/CE)
(MedPage Today) -- Cigarette smoking -- both past and present -- was associated with an increased risk of invasive breast cancer among postmenopausal women, a prospective cohort study found. (Source: MedPage Today Hematology/Oncology)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 6:18:16 pm
Breast Cancer - news item 12 of 119
Tissue "Highways" May Give Breast Cancer Insight
In a potential breakthrough for breast cancer, researchers have identified that the way tissue is arranged in and around tumors can help predict the path of the deadly disease, thereby aiding in treatment architecture. Patricia Keely, an associate professor of cell and regenerative biology at the University of Wisconsin-Madison School...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 4:00:00 pm
Breast Cancer - news item 13 of 119
Obesity may increase risk for triple-negative breast cancer
Data from the Women’s Health Initiative study indicate a link between obesity and estrogen receptor positive breast cancer, and also suggest that obese women have an increased risk for triple-negative breast cancer. (Source: MedWire News - Breast Cancer)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 2:27:50 pm
Breast Cancer - news item 14 of 119
Symposium zeroes in on new discoveries in breast cancer
(Source: Cancer)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 2:19:53 pm
Breast Cancer - news item 15 of 119
Identifying Risk Factors for Triple-Negative Breast Cancer
Two of the largest studies to date looking at triple-negative breast cancer have found that obesity, physical inactivity, and multiple pregnancies increase the risk for the disease. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 2:10:20 pm
Breast Cancer - news item 16 of 119
ECR: Sectra touts feasibility of color mammography
The combination of low-dose photon-counting and contrast-enhanced tomosynthesis may provide a diagnostic benefit, according to a study published in the February issue of Radiology and presented at a symposium dedicated to breast cancer detection and ways of improving cancer detection with photon-counting technology at the 2011 European Congress of Radiology (...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 1:12:02 pm
Breast Cancer - news item 17 of 119
Breast cancer survivors may be at higher risk for falls
Breast cancer treatment may have an adverse effect on survivors of the disease by putting them at greater risk for falls, research suggests. (Source: CTV Health)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 11:36:24 am
Breast Cancer - news item 18 of 119
Ultrasound Elastography Developments Lead to Increased Sensitivity of Malignant Nodes
Ultrasound elastography is shown to raise sensitivity by 24 percent for preoperative assessment of axillary metastases in suspected breast cancer. Meanwhile, microbubbles identify sentinel lymph nodes, minimizing operations, according to researchers presenting at ECR 2011. (Source: Diagnostic Imaging)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 11:00:00 am
Breast Cancer - news item 19 of 119
Combining Genomics And Current Medicines Holds Great Promise For Personalized Cancer Therapy
Using recent advances in genomics, researchers have uncovered a genetic pathway that affects the development of breast cancer, work that could help predict which patients are at risk of relapse for the disease. By studying which genes are expressed - or "turned on" - in breast cancer, research led by...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 10:00:00 am
Breast Cancer - news item 20 of 119
Cancer Patients' Partners Become Ill Themselves
Katarina Sjövall has studied partners of individuals with colorectal cancer, lung cancer, breast cancer or prostate cancer. The study shows that the number of diagnosed diseases among partners increased by 25 per cent after the cancer diagnosis. "Having a close relative with cancer entails worry and anxiety and an increased...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 10:00:00 am
Breast Cancer - news item 21 of 119
Obesity may increase risk of triple-negative breast cancer
New findings confirm the risk of breast cancer among women who are obese and not physically active, and suggests additional mechanisms beyond estrogen. (Source: ScienceDaily Headlines)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 9:00:00 am
Breast Cancer - news item 22 of 119
New Study Shows Smoking Increases Risk Of Breast Cancer In Postmenopausal Women
Compared to women who had never smoked, breast cancer risk increased by nine percent among former smokers and by 16 percent among current smokers according to research by Karen Margolis, MD, a senior clinical investigator with the HealthPartners Research Foundation and her collaborators in a study that was published today...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 9:00:00 am
Breast Cancer - news item 23 of 119
The Lancet Publishes Results From Pivotal Study Of Eisai's Halavenâ„¢ Injection In Patients With Late-Stage Metastatic Breast Cancer
Eisai announced that results from the global Phase III clinical study "EMBRACE" (Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus Eribulin) will be published online in The Lancet. The EMBRACE study showed that Halaven (eribulin mesylate) Injection demonstrated a statistically significant increase in overall survival (hazard ratio 0.81, 95%...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 9:00:00 am
Breast Cancer - news item 24 of 119
ContextVision Introduces New Mammography And Next-Generation Interventional Radiology Solutions At ECR 2011
ContextVision, the software imaging partner for the most recognized medical imaging manufacturers worldwide, introduced two innovative solutions at the 2011 European Congress of Radiology (ECR). A mammography solution addresses current limitations of x-ray image diagnosis for the detection of breast cancer, while the interventional radiology solution helps achieve superior, real-time...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 9:00:00 am
Breast Cancer - news item 25 of 119
Ultrasound and algorithms could lead to better breast cancer screening
New research holds the promise of becoming a powerful new weapon in the fight against breast cancer. His complex computational research has led to a fast, inexpensive new method for using ultrasound and advanced algorithms to differentiate between benign and malignant tumors with a high degree of accuracy. (Source: ScienceDaily...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 6:00:00 am
Breast Cancer - news item 26 of 119
Breast cancer survivors at higher risk for falls
(Elsevier Health Sciences) In a study scheduled for publication in the April issue of the Archives of Physical Medicine and Rehabilitation, researchers from the Oregon Health & Science University Knight Cancer Institute, Portland, asked post-menopausal breast cancer survivors whether they had fallen in the past year and then tracked their...
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 4:00:00 am
Breast Cancer - news item 27 of 119
Beyond Recreational Physical Activity
Does physical activity help to reduce the risk of breast cancer in postmenopausal women? American Journal of Public Health (Source: Medscape Today Headlines)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 3:00:00 am
Breast Cancer - news item 28 of 119
Tumor-Specific HMG-Coa Reductase Expression in Primary Premenopausal Breast Cancer Predicts Response to Tamoxifen
The predictive value of HMG-CoAR expression is examined in relation to tamoxifen response for patients who have yet to reach menopause. Breast Cancer Research (Source: Medscape Today Headlines)
RSS Source:   Med Worm - Breast Cancer Fri, 4 Mar 2011 3:00:00 am
Breast Cancer - news item 29 of 119
EU OKs Avastin for breast cancer †FDA behind the times?
On Wednesday the European Commission approved the use of Avastin (bevacizumab) for treatment of advanced stage breast cancer. This decision, which follows from a recommendation of a European Union advisory panel, stands in marked contrast to the policies of the FDA. This past December the FDA announced that it planned...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 30 of 119
Exercise Training and Cytokines in Breast Cancer Survivors
Int J Sports MedDOI: 10.1055/s-0031-1271697AbstractThe purpose of this randomized controlled trial was to determine the effects of an 8-week (aerobic+strength) exercise training program (3 sessions/week) on the circulating cytokine levels of breast cancer survivors. We randomly allocated 16 female survivors of breast cancer (mean±SD age: 50±5 years) to an intervention...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 31 of 119
Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer
Natalie Ludyga, Natasa Anastasov, Iria Gonzalez-Vasconcellos, Manuela Ram, Heinz Hofler, Michaela Aubele (Paper from Mol. BioSyst.) Natalie Ludyga, Mol. BioSyst., 2011, DOI: 10.1039/c0mb00286k To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 32 of 119
Preliminary safety and efficacy results of laser immunotherapy for the treatment of metastatic breast cancer patients
Xiaosong Li, Gabriela L. Ferrel, Maria C. Guerra, Tomas Hode, John A. Lunn, Orn Adalsteinsson, Robert E. Nordquist, Hong Liu, Wei R. Chen (Paper from Photochem. Photobiol. Sci.) Xiaosong Li, Photochem. Photobiol. Sci., 2011, DOI: 10.1039/c0pp00306a To cite this article before page numbers are assigned, use the DOI form of...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 33 of 119
The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer. [Additions and Corrections]
VOLUME 285 (2010) PAGES 23829†23841 Dr. Shim's name was misspelled. The correct spelling is shown above. (Source: Journal of Biological Chemistry) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 34 of 119
ERK8 as an ERR{alpha} Corepressor [Signal Transduction]
ERK8 (MAPK15) is a large MAP kinase already implicated in the regulation of the functions of different nuclear receptors and in cellular proliferation and transformation. Here, we identify ERRα as a novel ERK8-interacting protein. As a consequence of such interaction, ERK8 induces CRM1-dependent translocation of ERRα to the cytoplasm and...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 35 of 119
Understanding fear of cancer recurrence in terms of damage to ‘everyday health competence’
AbstractAdvances in clinical treatments are resulting in cancer patients living longer, but with the threat of the disease returning at some later date. Anxiety associated with this fear of recurrence, which seems widespread among patients, can lead to an enhanced bodily awareness and a pronounced tendency to interpret mundane sensations...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 36 of 119
Lymphatic and blood vessels in basal and triple-negative breast cancers: characteristics and prognostic significance
Authors: Rabab A A Mohammed, Ian O Ellis, Ali M Mahmmod, E Claire Hawkes, Andrew R Green, Emad A Rakha & Stewart G Martin (Source: Modern Pathology AOP)
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 37 of 119
Tissue Analysis May Help Predict Breast Cancer Outcome
Researchers say changes seen in collagen could signal worse prognosis, but more study needed (Source: Cancercompass News: Breast Cancer)
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 38 of 119
Alternative TFAP2A isoforms have distinct activities in breast cancer
Conclusions: Our findings suggest that TFAP2A isoforms may be differentially regulated during breast tumourigenesis and this, coupled with differences in their transcriptional activity, may impact on tumour responses to tamoxifen therapy. These data also have implications for the interpretation of tumour studies that seek to correlate outcomes with TFAP2A expression...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 39 of 119
Expression of microRNAs and their gene targets are dysregulated in pre-invasive breast cancer
Conclusions: These data provide the first miRNA expression profile of normal breast epithelium and of pre-invasive breast carcinoma. Further, we demonstrate that altered miRNA expression can modulate gene expression changes that characterize these early cancers. We conclude that miRNA dysregulation likely plays a substantial role in early breast cancer development. (...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 40 of 119
Activation of Multiple Proto-oncogenic Tyrosine Kinases in Breast Cancer via Loss of the PTPN12 Phosphatase
Tingting Sun, Nicola Aceto, Kristen L. Meerbrey, Jessica D. Kessler, Chunshui Zhou, Ilenia Migliaccio, Don X. Nguyen, Natalya N. Pavlova, Maria Botero, Jian Huang, Ronald J. Bernardi, Earlene Schmitt, Guang Hu, Mamie Z. Li, Noah Dephoure, Steven P. Gygi, Mitchell Rao, Chad J. Creighton, Susan G. Hilsenbeck, Chad A. Shaw, Donna Muzny, Richard A. Gibbs, David A. Wheeler, C. Kent Osborne, Rachel...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 41 of 119
'Failed' Scots research leads to new ways of detecting breast cancer
SCOTTISH scientists have discovered an "exciting" new way of detecting different types of breast cancer, which could help doctors work out the best way to treat patien (Source: Scotsman.com News - Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant,...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 11:00:00 pm
Breast Cancer - news item 42 of 119
Eribulin Survival Benefit in Metastatic Breast Cancer: Data Published
The new chemotherapy, approved late last year, showed a clear survival benefit over treatment of physician's choice in heavily pretreated women. Medscape Medical News (Source: Medscape Today Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 6:59:39 pm
Breast Cancer - news item 43 of 119
Passive smoke 'ups breast cancer risk'
Conclusion This well-conducted analysis of cohort data has confirmed the increased risk of breast cancer among smokers, particularly those with high-intensity and long duration of smoking. This is perhaps unsurprising. The increased risk of breast cancer among non-smokers with extensive exposure to passive smoking was also statistically significant. However, the...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 5:10:00 pm
Breast Cancer - news item 44 of 119
Passive smoke 'raises breast cancer risk'
Conclusion This well-conducted analysis of cohort data has confirmed the increased risk of breast cancer among smokers, particularly those with high-intensity and long duration of smoking. This is perhaps unsurprising. The increased risk of breast cancer among non-smokers with extensive exposure to passive smoking was also statistically significant. However, the...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 5:10:00 pm
Breast Cancer - news item 45 of 119
Obesity And Physical Inactivity Significantly Raise Breast Cancer Risk
Very obese women have a 35% higher risk of developing triple-negative breast cancer and a 39% higher risk of estrogen receptor-positive breast cancer, scientists reported in Cancer Epidemiology, Biomarkers & Prevention. Physical inactivity was also associated with a higher chance of developing breast cancer. The authors say their findings hint...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 4:00:00 pm
Breast Cancer - news item 46 of 119
Drug May Boost Survival in Metastatic Breast Cancer (CME/CE)
(MedPage Today) -- Patients with heavily pretreated breast cancer gained more than two months of life with the microtubule inhibitor eribulin (Halaven) compared with a treatment of physician choice, final results of a large randomized trial showed. (Source: MedPage Today Hematology/Oncology)
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 3:13:06 pm
Breast Cancer - news item 47 of 119
Prognostic Value of Estrogen Receptor and Ki-67 Index after Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer Expressing High Levels of Proliferation at Diagnosis
Oncology 2010;79:255†261 (DOI:10.1159/000322189) (Source: Karger Publishers)
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 2:18:18 pm
Breast Cancer - news item 48 of 119
Efficacy and Safety of S-1 in Patients with Metastatic Breast Cancer: Retrospective Review in a Single Institution
Oncology 2010;79:273†277 (DOI:10.1159/000322371) (Source: Karger Publishers) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 2:18:18 pm
Breast Cancer - news item 49 of 119
Risk of Congestive Heart Failure in Metastatic Breast Cancer Patients taking Bevacizumab
A meta-analysis study of 3784 clinical trial patients from five clinical trials taking bevacizumab for breast cancer published in the Journal of Clinical Oncology has found that although the incidence for significant heart failure is low, patients have an increased risk of developing significant heart failure. (Source: Cancer Network)
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 2:00:02 pm
Breast Cancer - news item 50 of 119
An Appeal To The Caregiving Values Of Rural Women For Breast Cancer Prevention
In an effort to develop strategies for breast health awareness in rural populations researchers asked the question, "What message strategies will motivate Appalachian women to attend to breast health issues and become actively involved in their own breast health?" A new study published in the Journal of Consumer Affairs finds...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 10:00:00 am
Breast Cancer - news item 51 of 119
Scientists Target Aggressive Prostate Cancer
Researchers at the University of Michigan Comprehensive Cancer Center have identified a potential target to treat an aggressive type of prostate cancer. The target, a gene called SPINK1, could be to prostate cancer what HER2 has become for breast cancer. Like HER2, SPINK1 occurs in only a small subset of...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 10:00:00 am
Breast Cancer - news item 52 of 119
Breast Cancer Drug Eribulin Extends Survival
Title: Breast Cancer Drug Eribulin Extends SurvivalCategory: Health NewsCreated: 3/3/2011 11:00:00 AMLast Editorial Review: 3/3/2011 (Source: MedicineNet Cancer General) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 6:00:00 am
Breast Cancer - news item 53 of 119
Researchers pinpoint genetic pathways involved in breast cancer
(Michigan State University) Using recent advances in genomics, researchers have uncovered a genetic pathway that affects the development of breast cancer, work that could help predict which patients are at risk of relapse for the disease. (Source: EurekAlert! - Medicine and Health) MedWorm Message: Watch the new MedWorm demo and...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 4:00:00 am
Breast Cancer - news item 54 of 119
Student innovation at Rensselaer Polytechnic Institute could lead to better breast cancer screening
(Rensselaer Polytechnic Institute) Recent research by Rensselaer Polytechnic Institute doctoral student Sevan Goenezen holds the promise of becoming a powerful new weapon in the fight against breast cancer. His complex computational research has led to a fast, inexpensive new method for using ultrasound and advanced algorithms to differentiate between benign...
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 4:00:00 am
Breast Cancer - news item 55 of 119
Smoking increases risk of breast cancer in postmenopausal women, study shows
Postmenopausal women who smoke or used to smoke have up to a 16 percent higher risk of developing breast cancer compared to women who have never smoked, new research finds. (Source: ScienceDaily Headlines)
RSS Source:   Med Worm - Breast Cancer Thu, 3 Mar 2011 2:52:40 am
Breast Cancer - news item 56 of 119
Aldehyde dehydrogenase 1 expression is a predictor of poor prognosis in nodeâ€positive breast cancers: a longâ€term followâ€up study
Conclusions:  ALDH1 expression in primary cancer is an independent prognostic factor in nodeâ€positive breast cancer patients. (Source: Histopathology)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 57 of 119
Eribulin Improves Survival in Metastatic Breast Cancer
Among women with heavily pretreated metastatic breast cancer, eribulin mesilate may significantly improve survival compared to currently available treatments, according to a study published online March 3 in The Lancet. (Source: Modern Medicine)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 58 of 119
Bevacizumab in combination with paclitaxel retains breast cancer indication in EU
Source: PharmaTimes Area: News According to a PharmaTimes report, the EC has confirmed that bevacizumab in combination with paclitaxel will remain a treatment option for women with metastatic breast cancer in the EU, following an investigation into the drug's benefit-risk profile. However, the Commission agreed with a recommendation from the...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 59 of 119
Association of active and passive smoking with risk of breast cancer among postmenopausal women: cohort study
Source: BMJ Area: News This prospective US cohort study, based on the observational arm of the Women's Health Initiative Study, examined the link between smoking and risk of invasive breast cancer among postmenopausal women. The study involved 79,990 women aged 50-79 who were in the study during 1993-8. The main...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 60 of 119
Eribulin monotherapy vs. physician's choice of treatment in patients with metastatic breast cancer: RCT (EMBRACE)
Source: Lancet Area: News There is a great need for treatments with survival benefit for women with heavily pretreated metastatic breast cancer. Eribulin mesilate (E7389) is a non-taxane inhibitor of microtubule dynamics of the halichondrin class of antineoplastic drugs. It is a structurally modified synthetic analogue of halichondrin B, a...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 61 of 119
Metadherin enhances the invasiveness of breast cancer cells by inducing epithelial to mesenchymal transition
SummaryThe epithelialâ€mesenchymal transition (EMT) is a process in which polarized epithelial cells are converted into motile mesenchymal cells. During cancer development, EMT is conducive to tumor dissemination and metastatic spread. While, overexpression of MTDH in breast cancer cell lines and tissues has been found to be associated with aggressive tumor...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 62 of 119
Analysis of HP1α regulation in human breast cancer cells
In this report, we examined the background for HP1α protein downâ€regulation in invasive breast cancer cells. We identified a strict correlation between HP1α downâ€regulation at the protein level and the mRNA level. The HP1α mRNA downâ€regulation in invasive cancer cells was not caused by mRNA destabilization. Chromatin immunoprecipitation analysis of...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 63 of 119
Pre†and postpubertal irradiation induces mammary cancers with distinct expression of hormone receptors, erbb ligands, and developmental genes in rats
AbstractChildhood exposure to carcinogens renders a higher risk of breast cancer. The molecular mechanisms underlying cancer development after such exposure are not, however, well understood. Here we examined how the mechanism of cancer development relates to the age at exposure to ionizing radiation (IR) or the carcinogen 1â€methylâ€1â€nitrosourea (MNU). Preâ€...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 64 of 119
New Chemo Drug May Benefit Some Breast Cancer Patients
Eribulin increased median survival by 2.5 months in those with metastatic disease, study finds (Source: Cancercompass News: Breast Cancer)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 65 of 119
Study Shows Treatment With Eribulin Extends Lives Of Heavily Pre-Treated Breast Cancer Patients Compared With Treatments Of Physician's Choice
Extending the lives of women who have had extensive treatment for breast cancer that has spread is not a lost cause, conclude authors of a study published Online First in The Lancet. The study shows that monotherapy with the drug eribulin extends the lives of breast cancer patients by a...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 11:00:00 pm
Breast Cancer - news item 66 of 119
Active, passive smoking up cancer risk
MORGANTOWN, W.Va., March 2 (UPI) -- Women who have in any way been exposed to tobacco smoke for extended periods during their lives are more likely to get breast cancer, U.S. researchers say. (Source: Health News - UPI.com)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 9:53:50 pm
Breast Cancer - news item 67 of 119
Being too fat raises risk of deadly breast cancer
CHICAGO (Reuters) - Scientists know that being overweight increases the risk of breast cancers fed by estrogen, but being too fat may also increase the risk of triple-negative breast cancers, a less common and far more deadly type, U.S. researchers said on Tuesday. (Source: Reuters: Health)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 7:09:46 pm
Breast Cancer - news item 68 of 119
iCAD Features Image Analysis Solutions for Breast, Prostate and Colon Cancer Detection at the ECR 2011
NASHUA, N.H.--(Healthcare Sales & Marketing Network)-- iCAD, Inc. (Nasdaq:ICAD ), an industry-leading provider of advanced image analysis, workflow solutions and radiation therapies for the early identification and treatment of cancer, announces its featur... Devices, Radiology, Oncology iCAD, computer-aided detection, breast cancer, prostate cancer, colon cancer (Source: HSMN NewsFeed) MedWorm Message: Watch...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 7:08:02 pm
Breast Cancer - news item 69 of 119
ASCO Update on Bone-Modifying Drugs in Metastatic Breast Cancer
The update includes the novel drug denosumab, zoledronic acid, and pamidronate, but does not recommend one drug over the other. Medscape Medical News (Source: Medscape Nurses Headlines)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:44:37 pm
Breast Cancer - news item 70 of 119
Breast cancer mommy: Brave, beautiful...and bald
Meredith Israel didn't want her hair to fall out in clumps, so she shaved it off (Source: Health News: CBSNews.com)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 5:28:43 pm
Breast Cancer - news item 71 of 119
Breast cancer mommy on losing her hair: "Bald is beautiful"
Meredith Israel didn't want her hair to fall out in clumps, so she shaved it off (Source: Health News: CBSNews.com)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 5:28:43 pm
Breast Cancer - news item 72 of 119
Smoking ups breast cancer risk
Compared to postmenopausal women who had never smoked, breast cancer risk increased (more) (Source: AuntMinnie.com Headlines)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 5:05:57 pm
Breast Cancer - news item 73 of 119
First Genetic Analysis of Metastatic Melanoma: Prognostic Significance of the BRAF Mutation
For the first time, a series of metastatic melanoma (MM) patients have been genetically tested for the constitutively activating BRAF mutation and assessed for its prognostic significance as is routinely done for breast cancer (HER2) and chronic myeloid leukemia (ABL). (Source: Cancer Network)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 3:00:02 pm
Breast Cancer - news item 74 of 119
European Commission Continues to Support Avastin in Combination With Paclitaxel As An Effective Treatment Option for Women With Metastatic Breast Cancer
Basel, Switzerland, 02 March 2011 -Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the European Commission confirmed that Avastin (bevacizumab) in combination with paclitaxel will remain a treatment option for women with metastatic breast... (Source: Drugs.com - Pharma News)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 2:48:25 pm
Breast Cancer - news item 75 of 119
MRP8/ABCC11 Expression Is Regulated by Dexamethasone in Breast Cancer Cells and Is Associated to Progesterone Receptor Status in Breast Tumors
The ATP-binding cassette multidrug resistance protein 8 (MRP8/ABCC11) mediates the excretion of anticancer drugs. ABCC11 mRNA and protein levels were enhanced by DEX (dexamethasone) and by PROG (progesterone) in MCF7 (progesterone receptor-(PR-) positive) but not in MDA-MB-231 (PR-negative) breast cancer cells. This suggested a PR-signaling pathway involvement in ABCC11 regulation....
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 2:47:49 pm
Breast Cancer - news item 76 of 119
Erratum of “Role of CEACAM1, ECM, and Mesenchymal Stem Cells in an Orthotopic Model of Human Breast Cancer”
(Source: Anesthesiology Research and Practice)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 2:47:49 pm
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Secretory Carcinoma of Male Breast: Case Report and Review of the Literature
Conclusion. Though considered an indolent neoplasm, secretory carcinoma does metastasize to lymph nodes. Surgery in the form of mastectomy with axillary clearance is the treatment of choice. This paper includes a rare case report of secretory carcinoma in young male patient, with axillary lymph node metastasis in spite of the...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 2:47:49 pm
Breast Cancer - news item 78 of 119
17α-Ethynyl-5α-androstane-3α, 17β-diol Treatment of MNU-Induced Mammary Cancer in Rats
N-methyl-N-nitrosourea (MNU) induces estrogen-dependent mammary tumors in female Lewis rats. We explored the antineoplastic activity of a synthetic androstane derivative, 17α-ethynyl-5α-androstane-3α, 17β-diol (HE3235), as a single agent or in combination with docetaxel compared to tamoxifen, anastrazole, and docetaxel monotherapies against MNU-induced mammary tumors in female Lewis rats. Treatment with HE3235...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 2:47:49 pm
Breast Cancer - news item 79 of 119
Multidrug Resistance in Breast Cancer: From In Vitro Models to Clinical Studies
The development of multidrug resistance (MDR) and subsequent relapse on therapy is a widespread problem in breast cancer, but our understanding of the underlying molecular mechanisms is incomplete. Numerous studies have aimed to establish the role of drug transporter pumps in MDR and to link their expression to response to...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 2:47:49 pm
Breast Cancer - news item 80 of 119
Indiana HIE enrolls 1,500 docs in quality program
The Indiana Health Information Exchange (IHIE) -- the largest HIE in the nation -- announced Wednesday that enrollment in its Quality Health First Program has reached 1,500 physicians in 50 communities, improving care for more than one million patients throughout Indiana. The program is helping to improve screening rates for...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 2:19:58 pm
Breast Cancer - news item 81 of 119
Preventing Breast Cancer
Source: HealthDay - Related MedlinePlus Pages: Breast Cancer, Exercise and Physical Fitness, Obesity (Source: MedlinePlus Health News)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 2:11:08 pm
Breast Cancer - news item 82 of 119
How Familiar Are You with Your Breast Surgeon's Credentials and Training?
This isn't just idle curiosity on my part--it turns out that your surgeon's real-life experience and expertise can actually be a life-and-death matter. (Source: Breast Cancer Chronicles) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 1:39:33 pm
Breast Cancer - news item 83 of 119
Smoking elevates breast cancer risk, study finds
Postmenopausal women who previously or currently smoke are at greater risk of developing breast cancer compared to their counterparts who never lit up, a new study suggests. (Source: CTV Health)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 1:32:07 pm
Breast Cancer - news item 84 of 119
Naviscan Announces European Launch of Positron Emission Mammography
European Launch Marked By Presentations of Significant New Clinical Data Demonstrating the Value of PEM in Improving Treatment Decisions for Breast Cancer VIENNA, March 2, 2011 (HSMN NewsFeed) -- Naviscan, Inc., announces the European launch of the Na... Devices, Radiology, OncologyNaviscan, Positron Emission Mammography, 3-D Molecular Breast Imaging (Source: HSMN...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 12:20:11 pm
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AirXpanders Raises $8M Through Series C Financing and Working Capital Line
Strategic Financing to Support IDE Study and International Launch of First-Ever Patient-Controlled Tissue Expansion System for Mastectomy Patients PALO ALTO, CA--(Healthcare Sales & Marketing Network) - AirXpanders Inc., a company developing technology ... Devices, Oncology, Venture CapitalAirXpanders, tissue expansion, mastectomy, breast cancer (Source: HSMN NewsFeed)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 12:15:43 pm
Breast Cancer - news item 86 of 119
Oncoplastic surgery combining partial mastectomy with breast reconstruction using a free nipple-areola graft for ductal carcinoma in situ in a ptotic breast: Report of a case
We report a case of early breast cancer, which was treated successfully by oncoplastic surgery. A 65-year-old Japanese woman was referred to us for investigation of a grouped calcification on mammography of her left breast, detected during mass screening for breast cancer. No mass lesion was palpated, but we suspected...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 8:11:22 am
Breast Cancer - news item 87 of 119
Sentinel lymph node biopsy before versus after neoadjuvant chemotherapy for breast cancer
This article reviews the issues surrounding SLNB before vs. after NAC, according to the published literature and our experience. Content Type Journal ArticlePages 311-316DOI 10.1007/s00595-010-4404-zAuthors Kenzo Shimazu, Department of Breast and Endocrine Surgery, Osaka University, Graduate School of Medicine, 2-2-E10 Yamada-oka, Suita, Osaka, 565-0871 JapanShinzaburo Noguchi, Department of Breast and...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 8:11:17 am
Breast Cancer - news item 88 of 119
Clinicopathological analysis of ten patients with metaplastic squamous cell carcinoma of the breast
Conclusions Squamous cell carcinoma or MSCC of the breast with features of the triple-negative subtype seems to be associated with a poor prognosis; however, nodenegative patients are likely to have a favorable prognosis. Content Type Journal ArticlePages 328-332DOI 10.1007/s00595-009-4276-2Authors Michitaka Honda, Department of Breast Surgery, Tokyo Metropolitan Komagome Hospital, 3-18-22...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 8:11:15 am
Breast Cancer - news item 89 of 119
Women who smoke at ANY stage of their live 'are more likely to get breast cancer'
According to a study, women are 16 per cent more likely to suffer from the disease after the menopause – when most cases are diagnosed – if they smoke. (Source: the Mail online | Health)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 7:04:50 am
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Breast Cancer Incidence Rates No Longer Declining In US Women
A sharp decline in breast cancer incidence rates among non-Hispanic white women in the U.S. after a dramatic drop in the use of postmenopausal hormone therapy did not continue through 2007, according to a new study from the American Cancer Society and the National Cancer Institute. While there are several...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 7:00:00 am
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The TP53 gene polymorphisms and survival of sporadic breast cancer patients
Abstract The TP53 gene polymorphisms, Arg72Pro and PIN3 (+16 bp), can have prognostic and predictive value in different cancers including breast cancer. The aim of the present study is to investigate a potential association between different genotypes of these polymorphisms and clinicopathological variables with survival of breast cancer patients in...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:13:09 am
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Evaluation of a Trainer Phantom in the Learning Phase of Sentinel Lymph Node Identification in Breast Cancer
Conclusions Training on a phantom showed that this is a valuable teaching tool that enables surgeons to become familiar with gamma probes. It cannot replace the clinical training phase, but is an important aid to proficiency in intraoperative detection. Content Type Journal ArticlePages 1-7DOI 10.1007/s00268-011-0997-7Authors Pierre Lèguevaque, EA 3031, Laboratoire...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:02:27 am
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PALB2 mutations in familial breast and pancreatic cancer
Abstract PALB2 (Partner And Localizer of BRCA2) binds to and co-localizes with BRCA2 in DNA repair. Germline mutations in PALB2 have been identified in approximately 1†2% of familial breast cancer and 3†4% of familial pancreatic cancer cases. The goal of this study was to evaluate the prevalence of...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:00:45 am
Breast Cancer - news item 94 of 119
Mouse mammary tumor like virus sequences in breast milk from healthy lactating women
Abstract Mouse mammary tumor virus (MMTV) has been a long standing candidate as a potential cause of some human breast cancers. Forty years ago, electron microscopic images of MMTV-like particles were identified in milk from 5% of healthy lactating women. These observations, however, have not been confirmed by modern methods....
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:00:39 am
Breast Cancer - news item 95 of 119
U.S. Breast Cancer Rates No Longer Declining
Title: U.S. Breast Cancer Rates No Longer DecliningCategory: Health NewsCreated: 3/2/2011 11:00:00 AMLast Editorial Review: 3/2/2011 (Source: MedicineNet Cancer General) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:00:00 am
Breast Cancer - news item 96 of 119
Obesity May Boost Odds of Aggressive Breast Cancer in Older Women
Title: Obesity May Boost Odds of Aggressive Breast Cancer in Older WomenCategory: Health NewsCreated: 3/1/2011 6:05:00 PMLast Editorial Review: 3/2/2011 (Source: MedicineNet Cancer General)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:00:00 am
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Study Finds Smoking Linked to Breast Cancer Risk
Title: Study Finds Smoking Linked to Breast Cancer RiskCategory: Health NewsCreated: 3/1/2011 10:05:00 PMLast Editorial Review: 3/2/2011 (Source: MedicineNet Weight Management General)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:00:00 am
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Breast Cancer Rates No Longer Declining
U.S. Breast Cancer Rates No Longer Declining (Source: eMedicineHealth.com)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:00:00 am
Breast Cancer - news item 99 of 119
Scientists say higher vitamin D intake will slash cancer, MS, and diabetes risk by half
(NaturalNews) In findings just published in the journal Anticancer Research, scientists at the University of California (UC) San Diego School of Medicine and Creighton University School of Medicine in Omaha have reported that most people need a much higher intake of vitamin D. And that simple step added to your...
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 6:00:00 am
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Obesity May Increase Risk of Breast Cancer
(Ivanhoe Newswire) †Obesity and inactiveness may increase the risk of triple-negative breast cancer, a subtype of breast cancer characterized by lack of estrogen, progesterone, and HER2 expression. (Source: Medical Headlines From Ivanhoe.com)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 4:00:00 am
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Passive smoke breast cancer link
Exposure to second-hand tobacco smoke as a child or adult appears to increase a woman's risk of breast cancer, experts say. (Source: BBC News | Health | UK Edition)
RSS Source:   Med Worm - Breast Cancer Wed, 2 Mar 2011 1:30:39 am
Breast Cancer - news item 102 of 119
Smoking May Increase Breast Cancer Risk
A new study shows a significant association between smoking and an increased risk of breast cancer. (Source: WebMD Health)
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:33:26 pm
Breast Cancer - news item 103 of 119
Higher vitamin D cuts cancer risk
New research suggests that a significantly higher vitamin D intake than previously thought is required to reach blood levels that can prevent or lower the incidence of breast cancer and other major diseases, Newswise.com reports. (Source: Modern Medicine) MedWorm Message: Watch the new MedWorm demo and find out how to...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 104 of 119
Menopausal Status in Breast Cancer Patients with Past Chemotherapy Determines Longâ€Term Hypoactive Sexual Desire Disorder
Conclusions.  Cancer treatment that leads to longâ€term ovarian failure in breast cancer patients has a negative impact on sexual desire. Patients with menopause induced by chemotherapy or GnRH agonists show significantly reduced sexual desire as compared to menstruating patients with past chemotherapy. Ochsenkühn R, Hermelink K, Clayton AH, von Schönfeldt...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 105 of 119
Passive smoking could raise risk of breast cancer
Women exposed to passive smoking have 32% risk of breast cancerRelated items from OnMedicaSmoking may worsen cancer painTeenage smoking numbers fall by 7%Exercise and good diet helps slow cell-aging processLung cancer survival in England remains poorBreast cancer risk increased to one in eight (Source: OnMedica Latest News)
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 106 of 119
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
Authors: Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama, Daming Gao, Alan Tseng, Richard S. Maser, Bo Zhai, Lixin Wan, Alejandro Gutierrez, Alan W. Lau, Yonghong Xiao, Amanda L. Christie, Jon Aster, Jeffrey Settleman, Steven P. Gygi, Andrew L. Kung, Thomas Look, Keiichi I. Nakayama, Ronald A. DePinho & Wenyi Wei The...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 107 of 119
Current and Former Smokers at Higher Breast Cancer Risk
Postmenopausal women who used to smoke or who currently smoke appear to be at a higher risk of invasive breast cancer than postmenopausal women who never smoked, according to a study published online March 1 in BMJ. (Source: Modern Medicine)
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 108 of 119
Breast Cancer in HIV-Infected Patients: A Retrospective Single-Institution Study
Discussion: The frequency of breast cancer in our population is low. We did not find any relationship among immunosuppression, obesity, and development of breast cancer. More studies are needed to elucidate the impact of HIV infection in the biology of breast cancer. (Source: Journal of the International Association of Physicians...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 109 of 119
Fruit Fiber Smoothies
Fiber from fruits is great for your health and is a powerful anticancer food. It's easy to add fruit fiber to your daily diet and reap the health benefits. Here's some ways to make a fiber-loaded fruit smoothie. Learn how to add fruit fiber to your diet. (Source: About.com Breast...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 110 of 119
The impact of breast cancer on mother†child relationships in Korea
Conclusions: Breast cancer brings new challenges in mother†child relationships with culturally framed issues. Findings can guide healthcare providers in giving relevant anticipatory guidance for women diagnosed with breast cancer and in considering familyâ€focused psychosocial and behavioral interventions for families with breast cancer. Copyright © 2011 John Wiley & Sons,...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 111 of 119
An evidence based strategy for follow up after breast conserving treatment for breast cancer
ConclusionsThis study shows that the risk of parenchymal LRR remains constant for at least 14 years and is significant enough to warrant routine longâ€term follow up mammography. Routine clinical examination contributes significantly to the detection of LRR only for the first 2 years. J. Surg. Oncol. © 2011 Wileyâ€Liss, Inc. (...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 112 of 119
{beta}-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis
In conclusion, WNT signaling seems highly relevant for basal-like and other subtypes of breast cancers metastasizing into the brain. β-catenin-independent WNT signaling, presumably via ROR1-2, plays a major role in this context. (Source: Carcinogenesis)
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 113 of 119
Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3
In conclusion, BITC could potentially be a rational therapeutic strategy for breast carcinoma in obese patients with high leptin levels. (Source: Carcinogenesis)
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 114 of 119
CC chemokine ligand 21 enhances the immunogenicity of the breast cancer cell line MCF-7 upon assistance of TLR2
This study explored the effects of CCL21-CCR7 ligation on cancer immunogenicity and related antitumor immune response, in the presence and absence of mitomycin C (MMC) treatment. CCL21-CCR7 binding upregulated human leukocyte antigen class I-restricted tumor antigen presentation with increased expression of human leukocyte antigen class I and transporter associated with...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 115 of 119
Estrogen receptor {alpha}-mediated transcription induces cell cycle-dependent DNA double-strand breaks
Prolonged exposure to estrogen increases breast cancer risk. Estrogen is known to induce chromosomal aberrations, yet the mechanisms by which estrogen promotes genomic instability are not fully understood. Here, we show that exposure of MCF-7 cells to 17β-estradiol (E2) induces DNA double-strand breaks (DSBs), as determined by the formation of...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 116 of 119
Ki-67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis
Conclusions: TNBC with high Ki-67 was associated with a more aggressive clinical feature despite a higher pCR rate. High proliferation index Ki-67 can be used for further classification of TNBC into two subtypes with different responses and prognosis. (Source: Breast Cancer Research) MedWorm Message: Watch the new MedWorm demo and...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 117 of 119
Population-Based Breast-Cancer Screening Not Best Use Of Limited Health-Care Resources In Low And Middle-Income Countries
There is increasing pressure from national and international advocacy groups on low-income and middle-income countries (LMICs) to implement population-based mammography screening. But according to a Personal View published Online First in The Lancet Oncology, this "one-size-fits-all" approach although proven to be effective in high-income countries would be impractical in most...
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 11:00:00 pm
Breast Cancer - news item 118 of 119
Being too fat raises risk of deadly breast cancer: study
CHICAGO (Reuters) - Scientists know that being overweight increases the risk of breast cancers fed by estrogen, but being too fat may also increase the risk of triple-negative breast cancers, a less common and far more deadly type, U.S. researchers said on Tuesday. (Source: Reuters: Health)
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 10:52:38 pm
Breast Cancer - news item 119 of 119
Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis
Journal of Medicinal ChemistryDOI: 10.1021/jm101541x (Source: Journal of Medicinal Chemistry)
RSS Source:   Med Worm - Breast Cancer Tue, 1 Mar 2011 8:32:18 pm