Cataracts - news item 1 of 48
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[ASCO SPECIAL ARTICLE] American Society of Clinical Oncology Clinical Practice Guideline Update on the Use of Pharmacologic Interventions Including Tamoxifen, Raloxifene, and Aromatase Inhibition for Breast Cancer Risk Reduction
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Discussion of risks and benefits of preventive agents by health providers is critical to patient decision making. (Source: Journal of Clinical Oncology)
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RSS Source: Med Worm - Cataracts Sun, 28 Jun 2009 11:00:00 pm
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Cataracts - news item 2 of 48
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Will Individuals With Alzheimer's Disease Benefit From Cataract Surgery?
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A multi-institutional team of researchers, led by the Mandel School of Applied Social Sciences at Case Western Reserve University, will begin a five-year, $2.9 million National Institutes of Health-funded study. They will examine the lives of patients with both cataracts and Alzheimer's disease (AD) to document how restored vision improves...
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RSS Source: Med Worm - Cataracts Sun, 28 Jun 2009 7:00:00 am
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Cataracts - news item 3 of 48
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OCRL1 mutations in Dent 2 patients suggest a mechanism for phenotypic variability.
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CONCLUSIONS: OCRL1 mutations can cause the renal phenotype of Dent disease, without acidosis or the dramatic eye abnormalities typical of Lowe syndrome. We propose a model to explain the phenotypic variability between Dent 2 and Lowe's based on distinctly different classes of mutations in OCRL1 producing splice variants. PMID: 19390221 [...
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RSS Source: Med Worm - Cataracts Sun, 28 Jun 2009 12:23:02 am
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Cataracts - news item 4 of 48
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Antioxidant status modifications by topical administration of dorzolamide in primary open-angle glaucoma.
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CONCLUSIONS. Topical administration of dorzolamide colirium diminishes oxidative stress in patients with glaucoma. PMID: 19551670 [PubMed - in process] (Source: European Journal of Ophthalmology)
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RSS Source: Med Worm - Cataracts Sat, 27 Jun 2009 8:07:49 pm
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Cataracts - news item 5 of 48
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Transversal ultrasound: Phacoemulsification with less foot pedal
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Transversal ultrasound that blends side-to-side and longitudinal ultrasound into an elliptical movement is an effective phacoemusification tool, particularly for dense cataracts. In an open-label, non-randomized comparative study of 331 patients who received phaco via a transversal ultrasound system, average effective phaco time and average foot pedal time were both very...
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RSS Source: Med Worm - Cataracts Sat, 27 Jun 2009 10:55:29 am
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Cataracts - news item 6 of 48
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Hydrocortisone: Cataracts following topical application: case report.
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Page: 24 (Source: Reactions Weekly) MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.
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RSS Source: Med Worm - Cataracts Fri, 26 Jun 2009 2:16:20 pm
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Cataracts - news item 7 of 48
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[Original articles] Salvage external beam radiotherapy after failed primary chemotherapy for bilateral retinoblastoma: rate of eye and vision preservation
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Conclusion: Salvage EBRT is highly effective in preserving eyes with useful vision in bilateral retinoblastoma after failed chemotherapy and focal treatments. These results will help the parents and ophthalmologists of such patients to reach an informed decision when weighing up the benefits of EBRT against its potential oncogenic effect. (Source:...
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RSS Source: Med Worm - Cataracts Tue, 23 Jun 2009 11:00:00 pm
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Cataracts - news item 8 of 48
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Phenotypic spectrum of dynamin 2 mutations in Charcot-Marie-Tooth neuropathy
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We report the first disease-causing mutation in the proline-rich domain of dynamin 2. Patients with a dynamin 2 mutation presented with a classical Charcot-Marie-Tooth phenotype, which was mild to moderately severe since only 3% of the patients were wheelchair-bound. The mean age at onset was 16 years with a large...
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RSS Source: Med Worm - Cataracts Tue, 23 Jun 2009 11:00:00 pm
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Cataracts - news item 9 of 48
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[Lens] Ovarian Hormone Modulation of Radiation-Induced Cataractogenesis: Dose-Response Studies
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Epidemiologic data on the effects of ovarian hormones in cataractogenesis are conflicting. In a rat model of radiation-induced cataracts, estrogen is shown to enhance the rate of cataract formation. (Source: Investigative Ophthalmology) MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed -...
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RSS Source: Med Worm - Cataracts Mon, 22 Jun 2009 11:00:00 pm
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Cataracts - news item 10 of 48
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New Consumer Information On Cataracts, Eye Infections Available On American Academy Of Ophthalmology's EyeSmart(TM) Web Site
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When is a cataract ready to be removed? What are the differences between the types of intraocular lenses (IOLs)? What are the symptoms for the most common eye infections? New resources that answer these and other common questions about cataracts and eye infections are now available on the American Academy...
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RSS Source: Med Worm - Cataracts Fri, 12 Jun 2009 11:00:00 am
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Cataracts - news item 11 of 48
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CLINICAL SCIENCES: Kinematic Analysis of Surgical Dexterity in Intraocular Surgery
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Conclusions Motion analysis differentiated between surgeons with varying levels of experience performing phacoemulsification tasks, thus demonstrating construct validity. This technique may be useful in the objective quantitative measurement of microsurgical skill with potential applications for training and research. (Source: Archives of Opthalmology)
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RSS Source: Med Worm - Cataracts Mon, 8 Jun 2009 4:00:00 am
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Cataracts - news item 12 of 48
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Radiation Health: Mechanisms of Radiation-Induced Cataracts in Astronauts
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(Source: Aviation, Space, and Environmental Medicine)
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RSS Source: Med Worm - Cataracts Mon, 8 Jun 2009 3:52:53 am
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Cataracts - news item 13 of 48
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Glare Testing in Patients with Cataract after Dilation
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Conclusions: BAT results are affected by dilation half of the time and can be adjusted by the change in VA from dilation to predict undilated BAT results.Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology)
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RSS Source: Med Worm - Cataracts Sun, 31 May 2009 11:00:00 pm
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Cataracts - news item 14 of 48
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Vision loss in older persons.
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Authors: Pelletier AL, Thomas J, Shaw FR Family physicians have an essential role in assessing, identifying, treating, and preventing or delaying vision loss in the aging population. Approximately one in 28 U.S. adults older than 40 years is visually impaired. Vision loss is associated with depression, social isolation, falls, and...
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RSS Source: Med Worm - Cataracts Sun, 31 May 2009 11:00:00 pm
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Cataracts - news item 15 of 48
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A rabbit model to study biochemical damage to the lens after vitrectomy: effects of N-acetylcysteine.
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Authors: Liu XC, Wang P, Yan H The purpose of the present study was to determine whether the biochemical effects of vitrectomy can be studied in rabbits and to assess the possible protective effects of N-acetylcysteine on the lens following vitrectomy. Twenty-four New Zealand rabbits (2.3-2.4 kg) were divided into...
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RSS Source: Med Worm - Cataracts Sun, 31 May 2009 11:00:00 pm
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Cataracts - news item 16 of 48
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Assessment of perceived difficulties by residents in performing routine steps in phacoemulsification surgery and in managing complications.
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CONCLUSIONS: This study identifies perceived difficulties that residents experience in routine cases of cataract surgery, highlighting specific areas in which they may benefit from additional training and practice. PMID: 19491983 [PubMed - in process] (Source: Canadian Journal of Ophthalmology)
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RSS Source: Med Worm - Cataracts Sun, 31 May 2009 11:00:00 pm
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Cataracts - news item 17 of 48
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Does the use of trypan blue during phacoemulsification affect the intraocular pressure?
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CONCLUSIONS: The use of trypan blue during small-incision cataract surgery does not have any effect on IOP during the immediate and early postoperative period. PMID: 19491985 [PubMed - in process] (Source: Canadian Journal of Ophthalmology) MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS...
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RSS Source: Med Worm - Cataracts Sun, 31 May 2009 11:00:00 pm
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Cataracts - news item 18 of 48
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Hereditary spastic paraplegias.
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We report a case of hereditary spastic paraplegia. This 38-year-old Chinese man has had lower limb weakness and spasticity for 10 years. He has normal cognition, no sensory deficits, ataxia or cataracts. There is a strong family history of spastic paraplegia. His paternal grandmother, great uncle, father, and elder brother...
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RSS Source: Med Worm - Cataracts Sun, 31 May 2009 11:00:00 pm
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Cataracts - news item 19 of 48
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Over-expression of translationally controlled tumor protein in lens epithelial cells seems to be associated with cataract development.
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Authors: Kim MJ, Lyu J, Sohn KB, Kim M, Cho MC, Joo CK, Lee K Inhibition of Na,K-ATPase causes opacification of the lens through abnormal increases in sodium and calcium levels, disturbed osmotic equilibrium, activation of proteolytic enzymes and cell damage. We previously identified Translationally Controlled Tumor Protein (TCTP) as...
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RSS Source: Med Worm - Cataracts Thu, 28 May 2009 11:00:00 pm
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Cataracts - news item 20 of 48
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A dominantly inherited mutation in collagen IV A1 (COL4A1) causing childhood onset stroke without porencephaly.
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We describe a three generation family with recurrent strokes and cataracts. The index case, a 14 year old boy presented with stroke at the age of 14 years and again 6 months later. His mother had long standing episodic headaches diagnosed as migraine. Grandmother was initially diagnosed with multiple sclerosis...
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RSS Source: Med Worm - Cataracts Wed, 27 May 2009 11:00:00 pm
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Cataracts - news item 21 of 48
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Pseudoexfoliation and the cataract surgeon: Preoperative, intraoperative, and postoperative issues related to intraocular pressure, cataract, and intraocular lenses
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This review provides a comprehensive assessment of intraocular pressure (IOP), phacoemulsification techniques, and intraocular lenses (IOLs) in pseudoexfoliation (PXF) eyes having cataract surgery. Pseudoexfoliation is ubiquitous and the most common cause for open-angle glaucoma worldwide. Cataracts occur with increased frequency in PXF eyes, and surgery is potentially complicated by the...
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RSS Source: Med Worm - Cataracts Wed, 27 May 2009 3:22:34 am
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Cataracts - news item 22 of 48
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[Clinical Trials] Comparing Ultrasound Biometry with Partial Coherence Interferometry for Intraocular Lens Power Calculations: A Randomized Study
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This study describes an effective statistical method which includes all cases, showing that there is no significant difference in refractive outcomes between the two methods. (Source: Investigative Ophthalmology)
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RSS Source: Med Worm - Cataracts Tue, 26 May 2009 4:00:00 am
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Cataracts - news item 23 of 48
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Astaxanthin: The Miracle Antioxidant and Anti-Inflammatory Nutrient
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In this study, astaxanthin was given to rats prior to heart attacks. - ASTAXANTHIN: Natural Astaxanthin, King of the Carotenoids by Bob Capelli - Available on Amazon.comAnother nutrient that's excellent for eye protection and reduces the harm caused by excessive ultraviolet radiation is astaxanthin, now offered by a number of...
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RSS Source: Med Worm - Cataracts Sun, 24 May 2009 7:00:00 am
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Cataracts - news item 24 of 48
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Cataract Surgery Complications Are Linked to a Urinary Drug
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Older men using a popular drug to treat urinary problems are more than twice as likely as those who do not to suffer serious complications after cataract surgery, a study has found. (Source: NYT > Health) MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu...
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RSS Source: Med Worm - Cataracts Wed, 20 May 2009 3:20:37 am
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Cataracts - news item 25 of 48
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JAMA PATIENT PAGE: Cataracts
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(Source: JAMA)
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RSS Source: Med Worm - Cataracts Tue, 19 May 2009 4:00:00 am
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Cataracts - news item 26 of 48
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EDITORIAL: Tamsulosin and the Intraoperative Floppy Iris Syndrome
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(Source: JAMA)
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RSS Source: Med Worm - Cataracts Tue, 19 May 2009 4:00:00 am
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Cataracts - news item 27 of 48
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ORIGINAL CONTRIBUTION: Association Between Tamsulosin and Serious Ophthalmic Adverse Events in Older Men Following Cataract Surgery
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Conclusions Exposure to tamsulosin within 14 days of cataract surgery was significantly associated with serious postoperative ophthalmic adverse events. There were no significant associations with exposure to other -blocker medications used to treat BPH. (Source: JAMA)
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RSS Source: Med Worm - Cataracts Tue, 19 May 2009 4:00:00 am
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Cataracts - news item 28 of 48
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Molecular characterization of co-occurring Duchenne muscular dystrophy and X-linked oculo-facio-cardio-dental syndrome in a girl
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We report on a 7-year-old girl who was referred for muscular hypotonia, with clinical features of Duchenne muscular dystrophy, including elevated serum creatine phosphokinase, pseudohypertrophy of calf muscles, and muscle weakness, which became evident at 3 years of age. In addition, she had multiple congenital anomalies including atrial septal defect,...
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RSS Source: Med Worm - Cataracts Fri, 15 May 2009 4:00:00 am
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Cataracts - news item 29 of 48
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Effects of Mode and Order of Administration on Generic Health-Related Quality of Life Scores
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Conclusions: Telephone administration yields significantly more positive HRQOL scores for all of the generic HRQOL measures except for the QWB-SA. The magnitude of effects was clearly important, with some differences as large as a half-standard deviation. These findings confirm the importance of considering mode of administration when interpreting HRQOL scores. (...
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RSS Source: Med Worm - Cataracts Fri, 15 May 2009 4:00:00 am
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Cataracts - news item 30 of 48
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NHS-A isoform of the NHS gene is a novel interactor of ZO-1.
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In conclusion, the NHS-A isoform of NHS is a novel interactor of ZO-1 and may have a role at tight junctions. This isoform is important in mammalian development especially of the organs in the head. PMID: 19447104 [PubMed - as supplied by publisher] (Source: Experimental Cell Research)
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RSS Source: Med Worm - Cataracts Thu, 14 May 2009 11:00:00 pm
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Cataracts - news item 31 of 48
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Surgical intervention for traumatic cataracts in children: Epidemiology, complications, and outcomes. - Reddy AK, Ray R, Yen KG.
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PURPOSE: To describe the presentation, treatment, and outcomes of a series of patients with unilateral traumatic cataracts. METHODS: Retrospective, noncomparative review of 25 consecutive children with unilateral traumatic cataracts managed at a single ins... (Source: SafetyLit: All (Unduplicated))
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RSS Source: Med Worm - Cataracts Sun, 10 May 2009 11:49:41 pm
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Cataracts - news item 32 of 48
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Applying Pharmacy School Training to Blindness Prevention in India
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May 8, 2009 Ashish Patel, a 4th-year University of California, San Francisco student pharmacist, is one of the next generation of pharmacists choosing to apply his training and expertise globally in new ways. In February 2009, Patel traveled to India to learn about eye health, current health care models and...
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RSS Source: Med Worm - Cataracts Fri, 8 May 2009 10:49:38 pm
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Cataracts - news item 33 of 48
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Negative screening tests in classical galactosaemia caused by S135L homozygosity
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In conclusion, galactosaemia must be considered in children who present with poor growth, hepatomegaly, developmental delay and cataracts and GALT enzyme analysis should be a first line test in such cases. Non-enzymatic screening methods such as urinary reducing substances and BIA for free galactose are not reliable in S135L homozygous...
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RSS Source: Med Worm - Cataracts Wed, 6 May 2009 5:46:24 am
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Cataracts - news item 34 of 48
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MYH9-Related Platelet Disorders
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Semin Thromb Hemost 2009; 35: 189-203DOI: 10.1055/s-0029-1220327ABSTRACTMyosin heavy chain 9 (MYH9)-related platelet disorders belong to the group of inherited thrombocytopenias. The MYH9 gene encodes the nonmuscle myosin heavy chain IIA (NMMHC-IIA), a cytoskeletal contractile protein. Several mutations in the MYH9 gene lead to premature release of platelets from the bone...
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RSS Source: Med Worm - Cataracts Sun, 3 May 2009 9:10:49 pm
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Cataracts - news item 35 of 48
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Absence of SPARC leads to impaired lens circulation.
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Authors: Greiling TM, Stone B, Clark JI SPARC is a matricellular glycoprotein involved in regulation of extracellular matrix, growth factors, adhesion, and migration. SPARC-null mice have altered basement membranes and develop posterior sub-capsular cataracts with cell swelling and equatorial vacuoles. Exchange of fluid, nutrients, and waste products in the avascular...
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RSS Source: Med Worm - Cataracts Sat, 2 May 2009 11:00:00 pm
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Cataracts - news item 36 of 48
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Get Great Shades Without Losing Your Shirt
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Overexposure to the sun can wreak havoc on your eyes. Sun damage can cause severe conditions such as photokeratitis (sunburn to the cornea), pterygium (tissue growth on the whites of eyes that can block vision), skin cancer on the eyelids, and has been implicated in the development of cataracts and...
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RSS Source: Med Worm - Cataracts Sat, 2 May 2009 9:00:00 am
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Cataracts - news item 37 of 48
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Characteristics of ethylnitrosourea-induced cataracts.
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CONCLUSIONS: Together, the results suggest that various proteins affect the formation and specific phenotypes of ENU-induced cataract mouse. PMID: 19401879 [PubMed - in process] (Source: Current Eye Research)
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RSS Source: Med Worm - Cataracts Thu, 30 Apr 2009 11:00:00 pm
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Cataracts - news item 38 of 48
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A comparative study of non-chopping rotation and axial rotation versus quick chop phacoemulsification techniques.
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CONCLUSION: The non-chopping rotation and axial rotation phacoemulsification techniques are advisable for removal of soft to medium-hard nuclei. For hard nuclei, chopping techniques are more successful. PMID: 19485284 [PubMed - indexed for MEDLINE] (Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the...
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RSS Source: Med Worm - Cataracts Thu, 30 Apr 2009 11:00:00 pm
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Cataracts - news item 39 of 48
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Relation of Age-related Cataract With Obesity and Obesity Genes in an Asian Population
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Obesity shows an inconsistent association with cataract. Causality has not been established. Polymorphisms at the fat mass- and obesity-associated (FTO) locus are associated with obesity and offer an opportunity to examine the obesity-cataract association using a mendelian randomization approach. The authors conducted a population-based study among Singaporean Malay adults (2004–2006)...
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RSS Source: Med Worm - Cataracts Thu, 30 Apr 2009 4:00:00 am
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Cataracts - news item 40 of 48
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Partial coherence interferometry in a teaching hospital
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Partial coherence interferometry (PCI) has an 8% to 22% failure rate for a variety of reasons such as mature cataract, inability to fixate secondary to macular degeneration, tremor, keratopathy, nystagmus, and vitreous hemorrhage. The new composite IOLMaster version 5 software has demonstrated a failure rate of 7.4%, primarily because of...
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RSS Source: Med Worm - Cataracts Fri, 24 Apr 2009 3:08:42 pm
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Cataracts - news item 41 of 48
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Intraocular pressure after phacoemulsification in eyes with pseudoexfoliation
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Pseudoexfoliation (PXF) syndrome is characterized by abnormal fibrillar deposits on the ocular structures that line the aqueous-bathed surfaces of the anterior segment. Chronic pressure elevation is attributed to blockage of the outflow channel by PXF material. Pigment dispersion and increased aqueous protein concentrations also contribute to the increased outflow resistance....
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RSS Source: Med Worm - Cataracts Fri, 24 Apr 2009 3:08:38 pm
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Cataracts - news item 42 of 48
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Microcoaxial cataract surgery outcomes: Comparison of 1.8 mm system and 2.2 mm system
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Conclusions: Both systems were safe and effective in microcoaxial phacoemulsification. The 1.8 mm system performed better with cortical-type cataract and the 2.2 mm system, with high-density nuclear-type cataract. (Source: Journal of Cataract and Refractive Surgery)
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RSS Source: Med Worm - Cataracts Fri, 24 Apr 2009 3:07:50 pm
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Cataracts - news item 43 of 48
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Mometasone furoate nasal spray is safe and effective for 1-year treatment of children with perennial allergic rhinitis
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Conclusions: Treatment with MFNS 100μg once daily for 1 year was well tolerated in children 6–11 years old, with negligible systemic exposure and no evidence of suppression of the hypothalamic–pituitary–adrenal axis or ocular changes. (Source: International Journal of Pediatric Otorhinolaryngology)
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RSS Source: Med Worm - Cataracts Wed, 22 Apr 2009 10:33:32 am
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Cataracts - news item 44 of 48
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LABORATORY SCIENCES: The Gel State of the Vitreous and Ascorbate-Dependent Oxygen Consumption: Relationship to the Etiology of Nuclear Cataracts
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Conclusions Ascorbate in the vitreous decreases exposure of the lens to oxygen. The catalyst for this reaction is not known, although free iron may contribute. The gel state of the vitreous preserves ascorbate levels, thereby sustaining oxygen consumption. Vitrectomy or advanced vitreous degeneration may increase exposure of the lens to...
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RSS Source: Med Worm - Cataracts Mon, 13 Apr 2009 4:00:00 am
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Cataracts - news item 45 of 48
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LABORATORY SCIENCES: Inhibition of Posterior Capsule Opacification by a Capsular Adhesion-Preventing Ring
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Conclusions The CAPR appears to prevent PCO formation by separating the anterior and posterior capsules and allowing circulation of aqueous humor, including growth inhibitory factors, into the equatorial space of the capsule through the holes and grooves in the ring. Clinical Relevance A CAPR may be useful for preventing PCO...
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RSS Source: Med Worm - Cataracts Mon, 13 Apr 2009 4:00:00 am
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Cataracts - news item 46 of 48
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LABORATORY SCIENCES: Disruption of the Posterior Chamber-Anterior Hyaloid Membrane Barrier During Phacoemulsification and Aspiration as Revealed by Contrast-Enhanced Magnetic Resonance Imaging
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Conclusion Changes in intraocular pressure can disrupt the posterior chamber–AHM barrier during PEA. Clinical Relevance Cataract surgeons should reexamine their surgical settings to avoid unnecessary stress on the eye. (Source: Archives of Opthalmology)
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RSS Source: Med Worm - Cataracts Mon, 13 Apr 2009 4:00:00 am
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Cataracts - news item 47 of 48
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LABORATORY SCIENCES: The Effect of Phacoemulsification Energy on the Redox State of Cultured Human Corneal Endothelial Cells
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Conclusion Redox fluorometry may serve as a useful indicator for the in vitro study of human corneal endothelial cell physiological response to ultrasonic stressors and potentially other nonoxidative stressors. Clinical Relevance Redox fluorometry in combination with human corneal endothelial cell morphometric measurements has potential to serve as an indicator of...
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RSS Source: Med Worm - Cataracts Mon, 13 Apr 2009 4:00:00 am
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Cataracts - news item 48 of 48
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CLINICAL SCIENCES: In Vitro Sealing of Clear Corneal Cataract Incisions With a Novel Biodendrimer Adhesive
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Conclusions Biodendrimer adhesives may be used to seal cataract wounds to prevent leakage and influx of fluid. (Source: Archives of Opthalmology) MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.
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RSS Source: Med Worm - Cataracts Mon, 13 Apr 2009 4:00:00 am
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