Cervical Cancer - news item 1 of 130
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Leea indica Ethyl Acetate Fraction Induces Growth-Inhibitory Effect in Various Cancer Cell Lines and Apoptosis in Ca Ski Human Cervical Epidermoid Carcinoma Cells
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In conclusion, these results suggested that LIEAF inhibited cervical cancer cells growth by inducing apoptosis and could be developed as potential anticancer drugs. (Source: Journal of Oncology)
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RSS Source: Med Worm - Cervical Cancer Tue, 1 Mar 2011 4:29:16 pm
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Cervical Cancer - news item 2 of 130
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Call for boys to get HPV vaccine
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Conclusion This was a large cohort study of men from selected populations that gives some insight into the burden of HPV infection in men. It does not assess the effects of vaccination in this population, but rather it investigates how the disease occurs in males. The researchers state that the...
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RSS Source: Med Worm - Cervical Cancer Tue, 1 Mar 2011 4:20:00 pm
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Cervical Cancer - news item 3 of 130
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Genital warts vaccine: Human papilloma virus jab should be given to boys, experts say
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Certain strains of the human papilloma virus are known to cause cervical cancer in women and have been linked to big increases in rates of oral cancer. (Source: the Mail online | Health)
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RSS Source: Med Worm - Cervical Cancer Tue, 1 Mar 2011 1:36:45 pm
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Cervical Cancer - news item 4 of 130
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Quality of life in cervical cancer survivors: a review of the literature and directions for future research.
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Conclusions: Future research directions should include (a) exploring and optimizing the positive outcomes of cervical cancer survivorship, (b) using interventions to reduce risky lifestyles or unhealthy behaviors, (c) conducting exploratory studies to determine the impact of cervical cancer survivorship on families, (d) conducting longitudinal studies to document the ongoing changes...
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RSS Source: Med Worm - Cervical Cancer Mon, 28 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 5 of 130
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Human Papillomavirus Testing in the Prevention of Cervical Cancer
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Strong evidence now supports the adoption of cervical cancer prevention strategies that explicitly focus on persistent infection with the causal agent, human papillomavirus (HPV). To inform an evidence-based transition to a new public health approach for cervical cancer screening, we summarize the natural history and cervical carcinogenicity of HPV and...
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RSS Source: Med Worm - Cervical Cancer Mon, 28 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 6 of 130
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Feasibility and safety of type C2 total extraperitoneal abdominal radical hysterectomy (TEARH) for locally advanced cervical cancer.
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Authors: Panici PB, Di Donato V, Plotti F, Musella A, Sansone M, Angioli R, Perniola G, Bellati F Radical hysterectomy represents the gold standard treatment in patients with early-stage cervical cancer and a valid choice of treatment, after neoadjuvant chemotherapy (NACT), in locally advanced tumors. Laparotomy is still considered the...
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RSS Source: Med Worm - Cervical Cancer Mon, 28 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 7 of 130
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Conservative management of early stage cervical cancer: Is there a role for less radical surgery?
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The objective of this report is to review the existing literature in this area and to describe an ongoing prospective study evaluating the safety and efficacy of conservative surgery in women with early stage cervical cancer. PMID: 21320670 [PubMed - in process] (Source: Gynecologic Oncology)
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RSS Source: Med Worm - Cervical Cancer Mon, 28 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 8 of 130
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Clinical Perspectives on the Role of the Human Papillomavirus Vaccine in the Prevention of Cancer
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Pharmacotherapy 31(3): 280-297 Abstract The role of human papillomavirus (HPV) in the genesis of cervical cancer has been well documented, and an increasing body of literature exists with regard to the role of HPV in other cancers, including cancers of the head and neck. With the recent expansion of the...
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RSS Source: Med Worm - Cervical Cancer Mon, 28 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 9 of 130
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Impact of postâ€therapy positron emission tomography on prognostic stratification and surveillance after chemoradiotherapy for cervical cancer
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CONCLUSIONS:The presence of a complete metabolic response at postâ€therapy FDGâ€PET is a powerful predictor for survival after chemoradiation. The very low rate of recurrence in patients with a complete metabolic response justifies a conservative followâ€up approach for these patients, because relapse is usually symptomatic and not detected by routine clinical...
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RSS Source: Med Worm - Cervical Cancer Mon, 28 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 10 of 130
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Domain-Specific Image Analysis for Cervical Neoplasia Detection Based on Conditional Random Fields
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This paper presents a domain-specific automated image analysis framework for the detection of pre-cancerous and cancerous lesions of the uterine cervix. Our proposed framework departs from previous methods in that we include domain-specific diagnostic features in a probabilistic manner using conditional random fields. Likewise, we provide a novel window-based performance...
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RSS Source: Med Worm - Cervical Cancer Mon, 28 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 11 of 130
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Study Shows Half Of Men In General Population Infected With HPV
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An Article published Online First by The Lancet shows that approximately 50% of men from a sample of the general population are infected with the human papillomavirus (HPV). Per year, 6% of men will acquire a new HPV 16 infection, the virus most well known for causing cervical cancer in...
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RSS Source: Med Worm - Cervical Cancer Mon, 28 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 12 of 130
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Pivotal Study Validates Roche's Cobas® HPV Test With HPV-16 And 18 Genotyping For Identifying Women At Highest Risk For Cervical Cancer
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Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that a study published online in the American Journal of Clinical Pathology demonstrated the ability of the cobas HPV Test to individually detect HPV-16 and HPV-18, two of the highest risk HPV genotypes causing 70 percent of cervical cancer cases. The ATHENA (Addressing...
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RSS Source: Med Worm - Cervical Cancer Fri, 25 Feb 2011 12:00:00 pm
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Cervical Cancer - news item 13 of 130
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Guided Therapeutics' Cervical Disease Detection Technology To Be The Subject Of A Presentation At The Upcoming ACOG Annual Meeting
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Guided Therapeutics, Inc. (OTCBB & OTCQB: GTHP) announced that its non-invasive and painless test for the early detection of cervical precancer, the LightTouchâ„¢, will be the subject of a presentation at The American College of Obstetricians and Gynecologists (ACOG) 59th Annual Clinical Meeting to be held April 30 - May...
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RSS Source: Med Worm - Cervical Cancer Fri, 25 Feb 2011 10:00:00 am
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Cervical Cancer - news item 14 of 130
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Pivotal Study Validates Roche’s cobas HPV Test with HPV-16 and 18 Genotyping for Identifying Women at Highest Risk for Cervical Cancer
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Roche announced that a study published online today in the American Journal of Clinical Pathology demonstrated the ability of the cobas HPV Test to individually detect HPV-16 and HPV-18, two of the highest risk HPV genotypes causing 70 percent of cervical cancer cases. The ATHENA (Addressing THE Need for Advanced...
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RSS Source: Med Worm - Cervical Cancer Fri, 25 Feb 2011 5:00:00 am
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Cervical Cancer - news item 15 of 130
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Genotyping of human papillomavirus in cervical intraepithelial neoplasia in a highâ€risk population
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In this study the frequency of HPV types was determined by HPV genotyping with reverse line blot hybridization in 200 cytobrushes of women with preneoplastic lesions in a highâ€risk population. HPV DNA was found in 89% of the lesions (83.3% of lowâ€grade squamous intraepithelial lesions and 93.6% of highâ€grade squamous...
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RSS Source: Med Worm - Cervical Cancer Thu, 24 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 16 of 130
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Potentiation of tumor radiotherapy by a radiationâ€inducible oncolytic and oncoapoptotic adenovirus in cervical cancer xenografts
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In this study, we attempted to improve the clinical outcomes of this combined therapy by modifying the p53â€targeted adenovirus to become radiationâ€responsive. The antiâ€tumor adenovirus was constructed by inserting a radiationresponsive expression cassette composed of the promoter of early growth responseâ€1 (Egrâ€1) and the proâ€apoptotic protein TRAIL. We showed that...
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RSS Source: Med Worm - Cervical Cancer Thu, 24 Feb 2011 2:22:33 pm
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Cervical Cancer - news item 17 of 130
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Inhibition of p600 Expression Suppresses Both Invasiveness and Anoikis Resistance of Gastric Cancer
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Conclusions Our results strongly suggest that p600 is involved in gastric cancer progression, and has a potential to be a new molecular target for gastric cancer therapy. Content Type Journal ArticlePages 1-9DOI 10.1245/s10434-010-1523-0Authors Hiroshi Sakai, Departments of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanKenoki Ohuchida,...
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RSS Source: Med Worm - Cervical Cancer Thu, 24 Feb 2011 7:08:20 am
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Cervical Cancer - news item 18 of 130
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GPs delay recording ovarian cancer diagnosis
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Study finds month long delays in GPs recording diagnosesRelated items from OnMedicaSymptoms don’t reliably predict ovarian cancerCancer drug fund announcedScotland reduces cancer waiting times but still misses target Smoking may worsen cancer painGuideline to help GPs spot cervical cancer early (Source: OnMedica Latest News) MedWorm Message: Watch the new MedWorm...
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RSS Source: Med Worm - Cervical Cancer Wed, 23 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 19 of 130
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Behind the Headlines: Should we protect girls from warts and cervical cancer?
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Doctors have called for schoolgirls to be vaccinated against genital warts, according to news reports. (Source: HealthcareRepublic Pharmacist News)
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RSS Source: Med Worm - Cervical Cancer Wed, 23 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 20 of 130
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Accuracy of 18-Fluoro-2-deoxy-d-glucose Positron Emission Tomography in the Pretherapeutic Detection of Occult Para-aortic Node Involvement in Patients with a Locally Advanced Cervical Carcinoma
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Conclusions Laparoscopic staging surgery seems warranted in LACC patients with negative PET scan who are candidates for definitive concurrent chemoradiotherapy or exenteration. Content Type Journal ArticlePages 1-8DOI 10.1245/s10434-011-1583-9Authors E. Leblanc, Centre Oscar Lambret, Lille, FranceH. Gauthier, Centre Oscar Lambret, Lille, FranceD. Querleu, Centre Claudius Regaud, Toulouse, FranceG. Ferron, Centre Claudius...
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RSS Source: Med Worm - Cervical Cancer Wed, 23 Feb 2011 10:04:43 pm
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Cervical Cancer - news item 21 of 130
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Predictors of cervical cancer screening for rarely or never screened rural appalachian women.
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Conclusion. The findings from this study may lead to the development of effective intervention and policies that increase cervical cancer screening in this population. PMID: 21317514 [PubMed - in process] (Source: Journal of Health Care for the Poor and Underserved)
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RSS Source: Med Worm - Cervical Cancer Wed, 23 Feb 2011 2:30:05 am
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Cervical Cancer - news item 22 of 130
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Zimbabwe: Govt Working on New Cervical Cancer Vaccine
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GOVERNMENT is working on adoption of a new cervical cancer vaccine that is likely to reduce the number of women who succumb to the disease, a senior Government official has said. (Source: AllAfrica News: Health and Medicine)
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RSS Source: Med Worm - Cervical Cancer Wed, 23 Feb 2011 1:54:38 am
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Cervical Cancer - news item 23 of 130
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Media coverage and public reaction to a celebrity cancer diagnosis
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Conclusion Increased public interest in disease prevention can follow a celebrity diagnosis. Although media coverage sometimes included public health information, articles typically focused on secondary instead of primary prevention. There is further potential to maximize the public health benefit of future celebrity diagnoses. (Source: Journal of Public Health)
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RSS Source: Med Worm - Cervical Cancer Tue, 22 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 24 of 130
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Role of MRI in Intracavitary Brachytherapy for Cervical Cancer: What the Radiologist Needs to Know
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CONCLUSION. MRI-guided intracavitary brachytherapy is an increasingly used therapy for the treatment of cervical cancer. This technique provides excellent visualization of intracavitary brachytherapy devices and allows accurate localization of residual tumor. It is important for radiologists to be familiar with the correct probe positioning as well as any potential complications. (...
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RSS Source: Med Worm - Cervical Cancer Mon, 21 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 25 of 130
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Identification and validation of genes involved in cervical tumourigenesis
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Conclusions: : Several novel genes were found to be differentially expressed in cervical cancer. MMP3, UBE2C and p16 protein overexpression in cervical cancers was confirmed by immunohistochemistry. These will need to be validated further in a larger series of samples. UBE2C could be evaluated further to assess its potential as a...
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RSS Source: Med Worm - Cervical Cancer Mon, 21 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 26 of 130
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The Value of MR Imaging When the Site of Uterine Cancer Origin Is Uncertain [Genitourinary Imaging]
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Conclusion: MR imaging is useful for determining the anatomic origin of uterine cancer and provides helpful information regarding invasion of adjacent structures. © RSNA, 2011 (Source: Radiology)
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RSS Source: Med Worm - Cervical Cancer Sun, 20 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 27 of 130
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Budget cutting US Republicans try to end funds for family planning and health reform
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(Source: BMJ Online First)
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RSS Source: Med Worm - Cervical Cancer Sun, 20 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 28 of 130
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Optimising human papillomavirus self-testing for high risk women
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Conclusions No one device was perfect, although suggestions for an optimal self-test most resembled the brush. These findings can be used to develop an optimal self-test collector for women. (Source: Sexually Transmitted Infections)
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RSS Source: Med Worm - Cervical Cancer Sun, 20 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 29 of 130
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Scientist urges human papilloma virus jabs for boys to stem oral cancer rise
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HPV, usually associated with cervical cancer, linked to throat and mouth tumoursBoys should be considered for routine vaccination against the human papilloma virus (HPV) to stem the rise of some oral cancers, according to a leading scientist working on the disease. The recommendation comes after studies which show that oral...
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RSS Source: Med Worm - Cervical Cancer Sun, 20 Feb 2011 3:06:00 pm
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Cervical Cancer - news item 30 of 130
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Prognostic value of podoplanin expression in intratumoral stroma and neoplastic cells of uterine cervical carcinomas
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CONCLUSIONS: These preliminary results suggest that podoplanin may have a role in host-tumor interactions and, as a result, may represent a favorable prognostic factor for squamous cervical carcinomas. (Source: Clinics)
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RSS Source: Med Worm - Cervical Cancer Sat, 19 Feb 2011 5:48:05 pm
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Cervical Cancer - news item 31 of 130
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Correlation of polymorphism of IL-8 and MMP-7 with occurrence and lymph node metastasis of early stage cervical cancer
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Summary The IL-8 and MMP-7 genes participate in the carcinogenesis of many malignancies, but the role of both genes in cervical cancer is not fully elucidated. The aim of this study was to determine the frequency of IL-8 and MMP-7 gene mutations and to assess their effects on the risk...
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RSS Source: Med Worm - Cervical Cancer Sat, 19 Feb 2011 6:36:10 am
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Cervical Cancer - news item 32 of 130
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Silencing MTA1 by RNAi reverses adhesion, migration and invasiveness of cervical cancer cells (SiHa) via altered expression of p53, and E-cadherin/β-catenin complex
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This study investigated whether and how MTA1 mediated cell proliferation, migration, invasion and adhesion in cervical cancer. MTA1 expression level was detected by Western blot in two cervical cancer cell lines of different invasion potentials. The effects of MTA1 expression on SiHa cell apoptosis, cycle, proliferation, migration, invasion and adhesion...
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RSS Source: Med Worm - Cervical Cancer Sat, 19 Feb 2011 6:36:09 am
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Cervical Cancer - news item 33 of 130
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Robotic surgery in gynecologic oncology
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Abstract The goal of this paper is to review the current data documenting the advantages of robotic surgery over open or laparoscopic surgery. The aim of this study is to compare the complications and perioperative outcome of robotic surgery with open and laparocopic surgery, in gynecologic oncology. The terms radical...
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RSS Source: Med Worm - Cervical Cancer Sat, 19 Feb 2011 6:17:06 am
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Cervical Cancer - news item 34 of 130
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Medical 'experts' pushing HPV vaccines told what not to say about them, including their death toll
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(NaturalNews) Two British doctors recently wrote a piece in the BBC urging the U.K. National Health Service (NHS) to switch from Merck's Cervarix human papillomavirus (HPV) vaccine to GlaxoSmithKline's (GSK) Gardasil HPV vaccine, in its mass vaccination program for young girls. And the two "experts" admit that they only say...
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RSS Source: Med Worm - Cervical Cancer Sat, 19 Feb 2011 6:00:00 am
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Cervical Cancer - news item 35 of 130
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Sun Pharmaceutical Industries Europe B.V. Withdraws Its Marketing Authorisation Application For Topotecan SUN (Topotecan)
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The European Medicines Agency has been formally notified by Sun Pharmaceutical Industries B.V. of its decision to withdraw its application for a centralised marketing authorisation for the medicinal product Topotecan SUN (topotecan) 1 mg and 4 mg powder for concentrate for solution for infusion. The medicine was developed as a...
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RSS Source: Med Worm - Cervical Cancer Fri, 18 Feb 2011 9:00:00 am
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Cervical Cancer - news item 36 of 130
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Radiotherapy quality assurance of the Japanese Gynecologic Oncology Group study (JGOG1066): a cooperative phase II study of concurrent chemoradiotherapy for uterine cervical cancer
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Conclusions Radiotherapy protocol compliance was favorable except for the EBRT boost indications. The results of this study validate the quality of radiotherapy in JGOG1066, and indicate that the final analysis will provide meaningful results. Content Type Journal ArticlePages 1-8DOI 10.1007/s10147-011-0196-4Authors Takafumi Toita, Department of Radiology, Graduate School of Medical Science,...
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RSS Source: Med Worm - Cervical Cancer Fri, 18 Feb 2011 5:44:21 am
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Cervical Cancer - news item 37 of 130
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Marketing authorisation application in EU for Topotecan SUN (topotecan) withdrawn
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Source: EMA Area: News The European Medicines Agency (EMA) has been formally notified by Sun Pharmaceutical Industries B.V. of its decision to withdraw its application for a centralised marketing authorisation for Topotecan SUN (topotecan) 1 mg and 4 mg powder for concentrate for solution for infusion. The medicine was developed...
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RSS Source: Med Worm - Cervical Cancer Thu, 17 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 38 of 130
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Decomposing income-related inequality in cervical screening in 67 countries
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Conclusions Considerable heterogeneity in the contributions of screening determinants among countries suggests interventions to reduce screening inequalities may require country-specific approaches. Content Type Journal ArticlePages 1-14DOI 10.1007/s00038-010-0224-6Authors Brittany McKinnon, Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Purvis Hall, 1020 Pine Avenue West, Montreal, QC H3A 1A2, CanadaSam Harper,...
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RSS Source: Med Worm - Cervical Cancer Thu, 17 Feb 2011 7:10:45 am
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Cervical Cancer - news item 39 of 130
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HPV types and variants among cervical cancer tumors in three regions of Tunisia
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AbstractCervical cancer is the second most common cancer among Tunisian women, and the incidence rates vary by region. Three Tunisian registries report ageâ€standardized rates of 6.3/105 in the central region, 5.4/105 in the north, and 2.7/105 in the south. Highâ€risk human papillomavirus (HPV) types and their variants differ in carcinogenic...
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RSS Source: Med Worm - Cervical Cancer Wed, 16 Feb 2011 7:12:35 am
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Cervical Cancer - news item 40 of 130
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CASP8 promoter polymorphism is associated with highâ€risk HPV types and abnormal cytology but not with cervical cancer
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AbstractOnly a small fraction of women infected with human papillomavirus (HPV) progress to cervical cancer pointing to additional risk factors including host genetics that might play a role in development of cervical cancer. Caspaseâ€8 (encoded by CASP8 gene) is crucial in generating cell death signals to eliminate potentially malignant cells....
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RSS Source: Med Worm - Cervical Cancer Wed, 16 Feb 2011 7:12:33 am
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Cervical Cancer - news item 41 of 130
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Global HPV vaccination
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(Source: BMJ Online First)
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RSS Source: Med Worm - Cervical Cancer Tue, 15 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 42 of 130
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Cervical Cancer Prevention Campaign Kicks Off in the Western Balkans - 25 January 2011
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SARAJEVO, Bosnia and Herzegovina — Although it is preventable and treatable, cervical cancer continues to be a major killer of women. Caused by sexually-acquired infection with human papillomavirus (HPV), cervical cancer claims the lives of more than 270,000 women every year, most of whom (85 per cent) live in developing...
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RSS Source: Med Worm - Cervical Cancer Tue, 15 Feb 2011 5:20:58 am
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Cervical Cancer - news item 43 of 130
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Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer
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Authors: C N Sreekanth, S V Bava, E Sreekumar & R J Anto (Source: Oncogene) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Cervical Cancer Sun, 13 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 44 of 130
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The wrong jab?
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Teenage girls are vaccinated on the NHS against cervical cancer, but sexual health experts argue that the vaccine being used should be changed to protect them from genital warts too. (Source: BBC News | Health | UK Edition)
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RSS Source: Med Worm - Cervical Cancer Sun, 13 Feb 2011 2:31:19 am
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Cervical Cancer - news item 45 of 130
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Second-hand smoke ups risk of abnormal Pap test
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NEW YORK (Reuters Health) - Another reason second-hand smoke is bad: there's a chance it can damage the tissues in a woman's cervix, putting her at higher risk for cervical cancer, a new study suggests. (Source: Reuters: Health)
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RSS Source: Med Worm - Cervical Cancer Fri, 11 Feb 2011 8:49:53 pm
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Cervical Cancer - news item 46 of 130
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Offspring of female rats given folic acid supplements develop more breast cancer: study
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(Source: St. Michael's Hospital News and Media)
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RSS Source: Med Worm - Cervical Cancer Fri, 11 Feb 2011 4:00:00 am
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Cervical Cancer - news item 47 of 130
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Palliative radiotherapy for cervical carcinoma, a systematic review.
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Conclusion: There is a dearth of information in the current literature to guide selection of an optimal palliative radiation schedule for treatment of patients with advanced cervical cancer. Based on this review and information from other solid tumors, there is no evidence to support the common belief that better and...
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RSS Source: Med Worm - Cervical Cancer Thu, 10 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 48 of 130
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European guidelines for quality assurance in cervical histopathology.
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Authors: Bulten J, Horvat R, Jordan J, Herbert A, Wiener H, Arbyn M Abstract The current paper presents Chapter 5 of the second edition of the European Guidelines for Quality Assurance in Cervical Cancer Screening, which deals with the histopathological diagnosis of lesions of the uterine cervix. It completes a...
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RSS Source: Med Worm - Cervical Cancer Thu, 10 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 49 of 130
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Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria [Research Articles]
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In this study, we show enzymatic properties, tissue distribution, and subcellular localization of human AGPAT3 and AGPAT5. In cells overexpressing these isoforms, the proteins were detected in the nuclear envelope and the endoplasmic reticulum. AGPAT5-GFP fusion protein was localized in the mitochondria of both Chinese hamster ovary and human epithelial...
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RSS Source: Med Worm - Cervical Cancer Thu, 10 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 50 of 130
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Acceptability of human papillomavirus vaccine among the urban, affluent and educated parents of young girls residing in Kolkata, Eastern India
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Conclusions:  The HPV vaccine seems to be well accepted among this subgroup of population if appropriately educated. (Source: Journal of Obstetrics and Gynaecology Research)
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RSS Source: Med Worm - Cervical Cancer Thu, 10 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 51 of 130
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Expression and significance of FOXM1 in human cervical cancer: A tissue micro-array study.
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Conclusion: The overexpression of FOXM1 protein in cervical cancer maybe associated with the progression of cervical cancer, and could be a potentially novel tumor marker useful for diagnosis and therapy of cervical cancer. PMID: 21291630 [PubMed - in process] (Source: Clinical and Investigative Medicine)
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RSS Source: Med Worm - Cervical Cancer Thu, 10 Feb 2011 8:30:03 pm
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Cervical Cancer - news item 52 of 130
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Depressive symptoms as a determinant of breast and cervical cancer screening in women: a population-based study in Ontario, Canada
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This study’s findings suggest that attention to the uptake of preventive services in women with depressive symptoms is warranted. Content Type Journal ArticlePages 1-10DOI 10.1007/s00737-011-0210-xAuthors Simone N. Vigod, Women’s College Hospital and Women’s College Research Institute, Toronto, ON CanadaPaul A. Kurdyak, University of Toronto, Toronto, ON CanadaDonna E. Stewart, University...
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RSS Source: Med Worm - Cervical Cancer Thu, 10 Feb 2011 6:56:27 pm
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Cervical Cancer - news item 53 of 130
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Neem leaf glycoprotein partially rectifies suppressed dendritic cell functions and associated T cell efficacy in stage IIIB cervical cancer patients.
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Authors: Roy S, Goswami S, Bose A, Chakraborty K, Pal S, Haldar A, Basu P, Biswas J, Baral R Myeloid derived dendritic cells (DCs) generated from monocytes of Cervical Cancer, Stage IIIB (CaCx IIIB) patients show a dysfunctional maturation, and thus anti-tumor T cell functions are dysregulated. In an objective...
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RSS Source: Med Worm - Cervical Cancer Tue, 8 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 54 of 130
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A novel HPV 16 L1-based chimeric virus-like particle containing E6 and E7 seroreactive epitopes permits highly specific detection of antibodies in patients with CIN 1 and HPV-16 infection
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Conclusion: We report for the first time that chimeric particles containing HPV-16 L1 protein fused with E6 and E7 seroreactive epitopes enable much better detection of IgG antibodies in the sera of CIN 1 patients positive for HPV-16 infection than those obtained with VLPs containing only the HPV-16 L1 protein....
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RSS Source: Med Worm - Cervical Cancer Tue, 8 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 55 of 130
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Research Team Honored For Innovative Science To Advance Cancer Research
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The Fifth Annual AACR Team Science Award will be given to a team of internationally renowned molecular biologists, epidemiologists, biostatisticians and clinicians from Fred Hutchinson Cancer Research Center and University of Washington who have worked together on human papillomavirus (HPV) for more than 20 years. This award recognizes an outstanding...
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RSS Source: Med Worm - Cervical Cancer Tue, 8 Feb 2011 7:00:00 am
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Cervical Cancer - news item 56 of 130
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Study Shows First Clear Benefits Of HPV Vaccine For Boys
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The vaccine for human papillomavirus (HPV) can prevent 90 percent of genital warts in men when offered before exposure to the four HPV strains covered by the vaccine, according to a new multi-center study led by H. Lee Moffitt Cancer Center and UCSF. The four-year, international clinical trial, which also...
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RSS Source: Med Worm - Cervical Cancer Mon, 7 Feb 2011 9:00:00 am
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Cervical Cancer - news item 57 of 130
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Kaiser Permanente Sets World Record for Cancer...
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February 1, 2011 †In honor of Cervical Cancer Screening Awareness month, hundreds of San Diegans participated in Kaiser Permanente’s “Women’s Focus on Health†event on Saturday, January 29 from 8:00 a.m. to 4 p.m., which offered cervical cancer screenings, mammograms, as well as laboratory testing for cardiovascular diseases. By...
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RSS Source: Med Worm - Cervical Cancer Sat, 5 Feb 2011 6:14:02 pm
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Cervical Cancer - news item 58 of 130
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In Africa, cancer is a burden that can no longer be ignored | Emilie Filou
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Cancer kills more people globally than HIV/Aids, TB and malaria, and in Africa it is becoming a growing health burdenIt's World Cancer Day today. Most people in the developed world will know someone who has suffered from or been affected by cancer. What fewer people know, however, is that people...
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RSS Source: Med Worm - Cervical Cancer Fri, 4 Feb 2011 1:30:00 pm
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Cervical Cancer - news item 59 of 130
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Nigeria: The Menace of Cervical Cancer
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Much more than the dreaded Acquired Immune Deficiency syndrome(AIDs) virus, is yet a deadlier killer-disease, especially among the women folk. With at least a woman dying every hour from the disease, cervical cancer is indeed a ravaging scourge that deserves to be tamed with all the efforts we can muster. (...
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RSS Source: Med Worm - Cervical Cancer Fri, 4 Feb 2011 7:17:40 am
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Cervical Cancer - news item 60 of 130
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Global cancer statistics.
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Authors: Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D The global burden of cancer continues to increase largely because of the aging and growth of the world population alongside an increasing adoption of cancer-causing behaviors, particularly smoking, in economically developing countries. Based on the GLOBOCAN 2008...
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RSS Source: Med Worm - Cervical Cancer Thu, 3 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 61 of 130
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Cervical Cancer Impacting Younger Women
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For young women, hard to detect cancers may develop and spread because of a physician's inability to diagnose the cancer at an early stage. (Source: Disabled World)
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RSS Source: Med Worm - Cervical Cancer Thu, 3 Feb 2011 10:15:13 pm
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Cervical Cancer - news item 62 of 130
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State of HPV16 integration in Lithuanian women with cervical neoplasia
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Abstract Cervical cancer morbidity and mortality in Lithuania is one of the biggest in the European Union. The main risk factor of cervical cancer is human papillomavirus (HPV). The deletion of the HPV E2 gene influences HPV DNA integration into the cell genome, as well as a rapid progression of...
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RSS Source: Med Worm - Cervical Cancer Thu, 3 Feb 2011 6:06:55 am
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Cervical Cancer - news item 63 of 130
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Screening for cervical cancer low for immigrant women
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Study led by St. Michael’s Hospital finds older, poorer women from South Asia have lowest screening rates (Source: St. Michael's Hospital News and Media)
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 11:58:42 pm
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Cervical Cancer - news item 64 of 130
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Increasing treatment accuracy for cervical cancer patients using correlations between bladder-filling change and cervix-uterus displacements: Proof of principle.
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CONCLUSIONS: Pre-treatment acquired VBF-scans may be used to substantially enhance treatment precision of cervical cancer patients. Application in adaptive therapy is promising and warrants further investigation. For highly conformal (IMRT) treatments, the use of a full bladder drinking protocol results in unacceptably large systematic set-up errors. PMID: 21295877 [PubMed -...
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 65 of 130
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Comparison of visual inspection with acetic acid (VIA) and cervical cytology to detect high grade cervical neoplasia among HIVâ€infected women in India
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AbstractHIVâ€infected women in India and other developing country settings are living longer on antiretroviral therapy, yet their risk for HPVâ€induced cervical cancer remains unabated due to lack of cost effective and accurate secondary prevention methods. Visual inspection after application of dilute acetic acid on the cervix (VIA) has not been...
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 66 of 130
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Looking ahead: A case for HPV testing of selfâ€sampled vaginal specimens as a cervical cancer screening strategy
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AbstractEven in the era of highly effective HPV prophylactic vaccines, substantial reduction in worldwide cervical cancer mortality will only be realized if effective early detection and treatment of the millions of women already infection and the millions who may not receive vaccination in the next decade can be broadly implemented...
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 67 of 130
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Correlation of p16INK4A expression and HPV copy number with cellular FTIR spectroscopic signatures of cervical cancer cells
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Kamila M. Ostrowska, Amaya Garcia, Aidan D. Meade, Alison Malkin, Ifeoluwapo Okewumi, John J. O'Leary, Cara Martin, Hugh J. Byrne, Fiona M. Lyng (Paper from Analyst) Kamila M. Ostrowska, Analyst, 2011, DOI: 10.1039/c0an00910e To cite this article before page numbers are assigned, use the DOI form of citation above. The...
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 68 of 130
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Depression chart threatens doctor-patient rapport
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GPs report that the depression questionnaire is too intrusiveRelated items from OnMedicaGuideline to help GPs spot cervical cancer earlyCommunity mental health services failing many usersChlamydia programme wasted moneyMore help to quit smoking in pregnancyHeart risks higher in overtime workers (Source: OnMedica Latest News)
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 69 of 130
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Kaiser Permanente Sets World Record for Cancer Screening
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February 1, 2011 †In honor of Cervical Cancer Screening Awareness month, hundreds of San Diegans participated in Kaiser Permanente’s “Women’s Focus on Health†event on Saturday, January 29 from 8:00 a.m. to 4 p.m., which offered cervical cancer screenings, mammograms, as well as laboratory testing for cardiovascular diseases. By...
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 5:28:59 pm
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Cervical Cancer - news item 70 of 130
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Proactive Healthcare Emphasized as United Kingdom Works to Reform Healthcare System and Clinical Pathology Laboratory Testing
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Speakers at Frontiers in Laboratory Medicine See Increased Role for Pathology DATELINE: BIRMINGHAM, ENGLAND†As our North American readers of Dark Daily arrive for work this morning, it will be late afternoon here in the United Kingdom and the last presentations on the second day of the 10th annual Frontiers...
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 7:00:34 am
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Cervical Cancer - news item 71 of 130
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Innovative Technology Uses Rust And Sand To Detect Lethal Diseases
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The next big thing in medical diagnostics could be minutes particles of rust, iron oxide, coated with the material from which sand is formed, silicon dioxide. These magnetic nanoparticles, a mere 29 to 230 nanometers across, can be used to trap antibodies to the virus that causes cervical cancer and...
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 7:00:00 am
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Cervical Cancer - news item 72 of 130
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Cervical cancer screening low amongst immigrant women
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Immigrant women in Ontario are not screened for cervical cancer as often as native-born Canadians, with the lowest rates being among older, poorer South Asians, new research shows. (Source: St. Michael's Hospital News and Media)
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RSS Source: Med Worm - Cervical Cancer Wed, 2 Feb 2011 4:00:00 am
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Cervical Cancer - news item 73 of 130
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The proper use of multimodality treatment in locally advanced cervical cancer.
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Authors: Katsaros D, Gribaudo S PMID: 21295332 [PubMed - as supplied by publisher] (Source: Gynecologic Oncology)
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RSS Source: Med Worm - Cervical Cancer Tue, 1 Feb 2011 11:00:00 pm
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Cervical Cancer - news item 74 of 130
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Nanotechnology: Detecting lethal diseases with rust and sand
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The next big thing in medical diagnostics could be minutes particles of rust, iron oxide, coated with the material from which sand is formed, silicon dioxide. These magnetic nanoparticles, a mere 29 to 230 nanometers across, can be used to trap antibodies to the virus that causes cervical cancer and...
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RSS Source: Med Worm - Cervical Cancer Tue, 1 Feb 2011 9:00:00 am
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Cervical Cancer - news item 75 of 130
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Prevalence of lymph nodes in the parametrium of radical vaginal trachelectomy (RVT) specimen.
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CONCLUSION: The presence of small lymph nodes in the parametrium of specimens of radical trachelectomy is low. In patients with early-stage cervical cancer, the incidence of metastasis is less than 1%. Preoperative assessment of the volume of the parametrium may indicate which patients need parametrial resection. PMID: 21292314 [PubMed -...
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RSS Source: Med Worm - Cervical Cancer Mon, 31 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 76 of 130
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Human papillomavirus vaccine initiation among adolescent girls in high-risk communities.
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CONCLUSIONS: About one-quarter of adolescent girls in this at-risk community had initiated HPV vaccine by mid-2008. Provider recommendation was the single most important factor associated with vaccination. Because a substantial proportion of parents remain undecided about HPV vaccine, health care providers can play a key role by providing needed information...
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RSS Source: Med Worm - Cervical Cancer Mon, 31 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 77 of 130
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Actions speak louder than words: the embodiment of trust by healthcare professionals in gynaeâ€oncology
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This article draws on qualitative data from semiâ€structured interviews with cervical cancer patients. The significance of body work in winning or, on occasions, undermining trust emerged as a key theme within the responses. Interpretations of professionals’ verbal and nonâ€verbal presentationsâ€ofâ€self were often mutually reinforcing and intrinsically linked †forming a...
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RSS Source: Med Worm - Cervical Cancer Mon, 31 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 78 of 130
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Human Papillomavirus E7 Enhances Hypoxia-Inducible Factor 1-Mediated Transcription by Inhibiting Binding of Histone Deacetylases
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Infection by human papillomaviruses (HPV) leads to the formation of benign lesions, warts, and in some cases, cervical cancer. The formation of these lesions is dependent upon increased expression of proangiogenic factors. Angiogenesis is linked to tissue hypoxia through the activity of the oxygen-sensitive hypoxia-inducible factor 1 (HIF-1). Our studies...
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RSS Source: Med Worm - Cervical Cancer Mon, 31 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 79 of 130
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Activation of beta-catenin and Akt Pathways by Twist are Critical for the Maintenance of EMT Associated Cancer Stem Cell-like Characters
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Conclusions: Our results indicate that activation of beta-catenin and Akt pathways are required for the sustention of EMT-associated stem cell-like traits. (Source: BMC Cancer)
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RSS Source: Med Worm - Cervical Cancer Mon, 31 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 80 of 130
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Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming [Microbiology]
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Despite the availability of vaccines, human papillomavirus (HPV) infections remain a cause of significant cancer morbidity and mortality. We have previously shown that HPV16 E7 associates with and diminishes E2F6-containing polycomb repressive complexes. Here, we show that repressive trimethyl marks on lysine 27 of histone 3, which are necessary for...
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RSS Source: Med Worm - Cervical Cancer Mon, 31 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 81 of 130
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Thousands snub cancer screening
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THOUSANDS of Lothians women are risking cervical cancer by snubbing NHS invites for screening, despite high-profile awareness campaigns, it was revealed today. (Source: Scotsman.com News - Health)
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RSS Source: Med Worm - Cervical Cancer Mon, 31 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 82 of 130
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Detecting lethal diseases with rust and sand
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(Inderscience Publishers) The next big thing in medical diagnostics could be minutes particles of rust, iron oxide, coated with the material from which sand is formed, silicon dioxide. These magnetic nanoparticles, a mere 29 to 230 nanometers across, can be used to trap antibodies to the virus that causes cervical...
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RSS Source: Med Worm - Cervical Cancer Mon, 31 Jan 2011 4:00:00 am
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Cervical Cancer - news item 83 of 130
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[Review] Fertility-sparing surgery in patients with cervical cancer
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There are several types of fertility saving procedures that can be done in patients with cervical cancer, which differ in terms of surgical approach and extent of paracervical resection. This review assesses oncological and pregnancy results after different procedures. The oncological results of vaginal radical trachelectomies (VRT) and abdominal radical...
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RSS Source: Med Worm - Cervical Cancer Sat, 29 Jan 2011 1:19:13 pm
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Cervical Cancer - news item 84 of 130
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[Correspondence] HPV types in early-onset cervical cancer †Authors' reply
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We appreciate the request from Paolo Rossi and Guglielmo Ronco for detailed information about the age distribution for vaccine types of human papillomavirus (HPV) to estimate the proportion of cases that could be prevented by vaccination and age groups. In the , we provide the proportion of cases caused by either...
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RSS Source: Med Worm - Cervical Cancer Sat, 29 Jan 2011 1:19:09 pm
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Cervical Cancer - news item 85 of 130
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[Correspondence] HPV types in early-onset cervical cancer
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Silvia de Sanjose and colleagues' study in the November, 2010, issue of The Lancet Oncology is an important source of information to plan future strategies for prevention of cervical cancer. As noted in Cosette Wheeler's comment, some useful insights come from the identification of differences between types of human papillomavirus (...
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RSS Source: Med Worm - Cervical Cancer Sat, 29 Jan 2011 1:19:08 pm
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Cervical Cancer - news item 86 of 130
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DH hails cervical cancer vaccination uptake as 'success'
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A cervical cancer vaccination programme aimed at girls is one of the most successful in the world, according to the Department of Health. (Source: Nursing Times Breaking News)
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RSS Source: Med Worm - Cervical Cancer Fri, 28 Jan 2011 9:31:00 am
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Cervical Cancer - news item 87 of 130
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Cervical Cancer Jab Uptake Increases, UK
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Over 84 per cent of girls aged 13-14 have helped protect themselves against cervical cancer by getting all three doses of the HPV vaccine and more than four million doses of the vaccine have been given in the first two years of the programme, Public Health Minister Anne Milton announced...
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RSS Source: Med Worm - Cervical Cancer Fri, 28 Jan 2011 8:00:00 am
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Cervical Cancer - news item 88 of 130
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Cervical cancer jab uptake increases
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Over 84 per cent of girls aged 13-14 have helped protect themselves against cervical cancer by getting all three doses of the HPV vaccine and more than four million doses of the vaccine have been given in the first two years of the programme, public health minister Anne Milton announced...
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RSS Source: Med Worm - Cervical Cancer Thu, 27 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 89 of 130
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HPV infection and cervical disease: A review
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Cervical cancer remains a significant problem worldwide particularly in underdeveloped countries. The disease and its financial impact are significant. Infection with the human papilloma virus (HPV) is necessary for the development of cervical cancer and its precursors. HPV also causes precancer and cancer elsewhere in the lower genital tract in...
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RSS Source: Med Worm - Cervical Cancer Thu, 27 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 90 of 130
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Column Calls For Focus On Reducing Cervical Cancer Deaths
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"We now have the medical know-how and the tools to stamp out [cervical cancer] once and for all," Cervical Cancer-Free America Director Jennifer Smith writes in an Atlanta Journal-Constitution opinion piece. She adds, "What we need now, as our country honors National Cervical Cancer Awareness Month in January, is the...
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RSS Source: Med Worm - Cervical Cancer Thu, 27 Jan 2011 10:00:00 am
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Cervical Cancer - news item 91 of 130
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Descriptive epidemiology of Pap test results from women with gynecologic symptoms in Georgia
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Cervical cancer is the fourth most common cancer among women in Georgia, after breast, colorectal, and corpus uteri cancer . The 2008 estimates of the cervical cancer burden in Georgia were 317 incident cases (age-adjusted incidence rate, 9.4 cases per 100000 women) and 169 cervical cancer-related deaths (age-adjusted mortality rate, 4.7...
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RSS Source: Med Worm - Cervical Cancer Wed, 26 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 92 of 130
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Four in five girls have had HPV jab
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More than 84% of 13-14 year olds have had three doses of HPV vaccineRelated items from OnMedicaParents unsure of HPV vaccine for daughters Under-25s risk chlamydia through embarrassmentPassive smoking causes 1 in 100 deathsGuideline to help GPs spot cervical cancer earlyFruit & veg cut risk of small baby (Source: OnMedica...
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RSS Source: Med Worm - Cervical Cancer Wed, 26 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 93 of 130
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The State of the Fight: Cervical Cancer
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Each month, in observance of the U.S. National Cancer Awareness Calendar, Stand Up To Cancer brings you The State of the Fight, a series of articles by those on the front lines of cancer treatment. We've asked our scientists to tease out myths from facts and report on breakthroughs in...
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RSS Source: Med Worm - Cervical Cancer Wed, 26 Jan 2011 5:52:50 pm
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Cervical Cancer - news item 94 of 130
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Updated Center to Reduce Cancer Health Disparities (CRCHD) website
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The Center to Reduce Cancer Health Disparities (CRCHD) has recently updated some of its Web pages. Site updates include: A new Integrated Networks section with information on the Geographical Management of Cancer Health Disparities Program (GMaP) and the National Outreach Network (NON). Relevant job opportunities from our grantees. New "Cancer...
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RSS Source: Med Worm - Cervical Cancer Wed, 26 Jan 2011 2:56:00 pm
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Cervical Cancer - news item 95 of 130
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MSP in cancer awareness drive
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LOTHIANS SNP MSP Shirley-Anne Somerville is using her website and Facebook page to increase awareness of cervical cancer and how to prevent it during Cervical Cancer Preventio (Source: Scotsman.com News - Health)
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RSS Source: Med Worm - Cervical Cancer Tue, 25 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 96 of 130
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Enantiospecific adjuvant activity of cationic lipid DOTAP in cancer vaccine
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Abstract Commercially available DOTAP is a racemic mixture of two enantiomers. The adjuvanticity of each isomer was examined using a peptide/lipid complex as a therapeutic vaccine in an established murine cervical cancer model. This simple vaccine consists of a cationic lipid (DOTAP) and a major histocompatibility complex (MHC) class Iâ€...
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RSS Source: Med Worm - Cervical Cancer Tue, 25 Jan 2011 9:34:38 pm
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Cervical Cancer - news item 97 of 130
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Analytical and clinical performances of a restriction fragment mass polymorphism assay for detection and genotyping of a wide spectrum of human papillomaviruses
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AbstractMatrixâ€assisted laser desorption ionization timeâ€ofâ€flight (MALDIâ€TOF) mass spectrometryâ€based restriction fragment mass polymorphism (RFMP) assay was adapted to human papillomavirus (HPV) genotyping. The analytical sensitivity and the clinical utility were evaluated by testing defined HPV genome equivalents and a total of 426 specimens composed of normal cytology, atypical squamous cells of...
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RSS Source: Med Worm - Cervical Cancer Tue, 25 Jan 2011 10:36:22 am
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Cervical Cancer - news item 98 of 130
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Prevalence of human papillomavirus among women with normal cervical cytology in Kuwait
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This study was undertaken to determine the prevalence and type specific distribution of human papillomavirus (HPV) in women with normal cervical cytology in Kuwait. The study is the first of its type in Kuwait and one of few in the Middle East. The age specific distribution of HPV types was...
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RSS Source: Med Worm - Cervical Cancer Tue, 25 Jan 2011 10:36:21 am
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Cervical Cancer - news item 99 of 130
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Aberrant microRNA expression in human cervical carcinomas
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Abstract Because altered microRNAs (miRNAs) expression patterns have been observed in a variety of diseased tissues, miRNA expression was compared in human cervical cancer tissues relative to adjacent normal cervical tissues in the present study. Microarray chips with 924 probes were used to detect the expression of miRNAs in cervical...
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RSS Source: Med Worm - Cervical Cancer Tue, 25 Jan 2011 5:45:48 am
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Cervical Cancer - news item 100 of 130
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Ultrasoundâ€guided tandem placement for lowâ€doseâ€rate brachytherapy in advanced cervical cancer minimizes risk of intraoperative uterine perforation
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ConclusionsWithin the present population, intraoperative ultrasound guidance of tandem placement was associated with no confirmed cases of uterine perforation. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd. (Source: Ultrasound in Obstetrics and Gynecology)
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RSS Source: Med Worm - Cervical Cancer Tue, 25 Jan 2011 1:47:11 am
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Cervical Cancer - news item 101 of 130
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Pulsed brachytherapy: a modelled consideration of repair parameter uncertainties and their influence on treatment duration extension and daytime-only "block-schemes"
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Conclusion: Although daytime-only "block-scheme" PB for cervical cancer has not yet been employed clinically, the possibilities appear to be theoretically promising, providing the overall (external beam plus brachytherapy) treatment duration is not extended relative to current practice, such that additional tumour repopulation becomes a concern. PMID: 21266397 [PubMed - as...
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RSS Source: Med Worm - Cervical Cancer Mon, 24 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 102 of 130
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Cytology history preceding cervical cancer diagnosis: a regional analysis of 286 cases
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Authors: M Gök, L Rozendaal, J Berkhof, O Visser, C J L M Meijer & F J van Kemenade (Source: British Journal of Cancer AOP) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Cervical Cancer Mon, 24 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 103 of 130
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Prevalence of human papillomavirus genotypes in cytologic abnormalities from unvaccinated women living in northâ€western Spain
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We report the results of a population study carried out in a region of northâ€western (NW) Spain aimed at determining the prevalence of single and multiple infections by 35 types of HPV using lowâ€density microarrays for 113 cases with negative for intraepithelial lesions or malignancies; 588 with atypical squamous cells...
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RSS Source: Med Worm - Cervical Cancer Mon, 24 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 104 of 130
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Does Chocolate Hold the Key to Curing HPV
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Indulgent chocolate treats may be the best-known and most widely appreciated product of the cacao tree, but new scientific research from New York Based Cacao Biotechnologies is uncovering potential new applications for the antioxidant-rich beans which could spur an innovative approach to treating human papillomavirus (HPV), a precursor to cervical...
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RSS Source: Med Worm - Cervical Cancer Mon, 24 Jan 2011 9:20:51 pm
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Cervical Cancer - news item 105 of 130
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Progress Report: SU2C's PI3K Dream Team Treating Women's Cancers
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In honor of Cervical Cancer Awareness month, meet SU2C's PI3K Dream Team. (Source: Stand Up 2 Cancer)
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RSS Source: Med Worm - Cervical Cancer Mon, 24 Jan 2011 4:46:28 am
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Cervical Cancer - news item 106 of 130
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Human Papillomavirus Vaccine: An Updated Position Statement of the Society for Adolescent Health and Medicine
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Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide, causing almost all cases of genital warts and cervical cancer. In June 2006, the Food and Drug Administration (FDA) approved a three-dose quadrivalent HPV vaccine for use in females, and in October 2009, the FDA approved a three-dose bivalent...
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RSS Source: Med Worm - Cervical Cancer Mon, 24 Jan 2011 4:25:49 am
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Cervical Cancer - news item 107 of 130
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Non-Genotoxic p53-Activators and their Significance as Antitumor Therapy of Future.
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Authors: Nayak SK, Panesar PS, Kumar H The tumor suppressor protein p53 mediates critical cellular functions including regulation of cell cycle, apoptosis, DNA repair, and senescence. This protein has been found to be inactivated or functionally down-regulated in several malignancies such as Li-Fraumeni syndrom, hepatocellular carcinoma, breast cancer, cervical cancer,...
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RSS Source: Med Worm - Cervical Cancer Sun, 23 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 108 of 130
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Intra-operative detection of nodal metastasis in early stage cervical cancer: A survey of the practice patterns of SGO members.
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CONCLUSION: Practice patterns of SGO members are considerably diverse, which is reflective of the conflicting evidence available in the literature. Well designed studies are required to determine the best overall approach. PMID: 21269668 [PubMed - as supplied by publisher] (Source: Gynecologic Oncology)
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RSS Source: Med Worm - Cervical Cancer Sun, 23 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 109 of 130
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Large performance variation does not affect outcome in the Finnish cervical cancer screening programme
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Conclusions:  There were large variations in the sensitivity†specificity tradeâ€off between laboratories, reflected in all performance indicators as well as in the test validity estimates of the reâ€evaluation phase, but not in screening effectiveness. Even though performance variations do not always have an impact on the effectiveness of screening, they...
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RSS Source: Med Worm - Cervical Cancer Sun, 23 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 110 of 130
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Flexibility call for cervical screening
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EMPLOYERS and GPs must help women do more to protect themselves from cervical cancer, a charity has warned. (Source: Scotsman.com News - Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Cervical Cancer Sun, 23 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 111 of 130
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Optional screening strategies for cervical cancer using standalone tests and their combinations among low- and medium-income populations in Latin America and Eastern Europe
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Conclusions The Pap test is a highly specific screening option in populations with medium-range CC prevalence. Combined testing for HPV in this scenario may yield slightly better positive predictive values in women ≥35 years of age with LSIL, but at a high incremental cost. (Source: Journal of Medical Screening)
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RSS Source: Med Worm - Cervical Cancer Sat, 22 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 112 of 130
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Implementing the national invasive cervical cancer audit: correlation between local and regional classification
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Conclusions Accurate and consistent classification of invasive cervical cancer cases is essential in order to obtain useful information on the efficiency of the national screening programme at a local, regional and national level. The use of a national algorithm would provide reassurance that all data used in the national evaluation...
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RSS Source: Med Worm - Cervical Cancer Sat, 22 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 113 of 130
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Is human papillomavirus screening preferable to current policies in vaccinated and unvaccinated women? A cost-effectiveness analysis
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Conclusions Our findings strongly support changing the Pap screening policy to the use of HPV DNA as a primary test with Pap test triage for both vaccinated and unvaccinated women. (Source: Journal of Medical Screening)
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RSS Source: Med Worm - Cervical Cancer Sat, 22 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 114 of 130
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A study of chronic pelvic pain after radiotherapy in survivors of locally advanced cervical cancer
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Conclusions CCSs have a higher prevalence of pain in lower back and hips than women in the general population, which might be due to late effects of radiation. 35/92 (38%) of the CCSs suffer from chronic pelvic pain, shown to be associated with high overall mental and somatic morbidity. Implications...
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RSS Source: Med Worm - Cervical Cancer Sat, 22 Jan 2011 7:15:23 pm
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Cervical Cancer - news item 115 of 130
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Heterotrimeric stimulatory GTPâ€binding proteins inhibit cisplatinâ€induced apoptosis by increasing Xâ€linked inhibitor of apoptosis protein expression in cervical cancer cells
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This study investigated the effect of Gαs on apoptosis triggered by cisplatin and its underlying molecular mechanism in cervical cancer cells. Stable expression of constitutively active Gαs (GαsQL) decreased the release of cytochrome c from the mitochondria to the cytosol and cleavage of caspaseâ€3 and poly(ADPâ€ribose) polymerases in HeLa cells...
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RSS Source: Med Worm - Cervical Cancer Fri, 21 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 116 of 130
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Heterotrimeric stimulatory GTPâ€binding proteins inhibit cisplatinâ€induced apoptosis by increasing XIAP expression in cervical cancer cells
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This study investigated the effect of Gαs on apoptosis triggered by cisplatin and its underlying molecular mechanism in cervical cancer cells. Stable expression of constitutively active Gαs (GαsQL) decreased the release of cytochrome c from the mitochondria to the cytosol and cleavage of caspaseâ€3 and poly (ADPâ€ribose) polymerases (PARP) in...
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RSS Source: Med Worm - Cervical Cancer Fri, 21 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 117 of 130
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Health reform law can help align Medicare with preventive care recommendations
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A significant gap exists between a government-commissioned task force's recommendations on preventive health services older Americans should receive and Medicare coverage for those services, a new UCLA-led study has found. But the researchers say the new health care reform law should be able to help mend the disconnect. In particular,...
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RSS Source: Med Worm - Cervical Cancer Fri, 21 Jan 2011 9:00:00 pm
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Cervical Cancer - news item 118 of 130
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Enhancing intentions to attend cervical cancer screening with a stage-matched intervention.
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Conclusions. Although direct effects are in line with stage assumptions of the HAPA, meditational analysis among pre- and post-intentional women indicated that similar processes accounted for post-manipulation intention. Future research testing stage models should account for the mediating processes, which explain the effects of the intervention. PMID: 21226782 [PubMed - in...
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RSS Source: Med Worm - Cervical Cancer Fri, 21 Jan 2011 7:45:44 am
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Cervical Cancer - news item 119 of 130
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Proliferation inhibition of human cervical cancer HeLa cells by Casticin in vitro
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Conclusion Casticin could inhibit the cell growth and lead to cell arrest in human cervical cancer HeLa cells, and the down-regulation of Cyclin B1 protein expression and activation of p21 protein might contribute to Casticin induced cell arrest in human cervical cancer HeLa cells. Content Type Journal ArticlePages 47-50DOI 10.1007/s10330-011-0711-0Authors...
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RSS Source: Med Worm - Cervical Cancer Fri, 21 Jan 2011 6:54:05 am
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Cervical Cancer - news item 120 of 130
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Cervical cancer vaccine: Get the facts
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Cervical cancer vaccine — A Mayo Clinic expert answers questions about the cervical cancer vaccine. (Source: MayoClinic.com Full Feed)
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RSS Source: Med Worm - Cervical Cancer Fri, 21 Jan 2011 5:00:00 am
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Cervical Cancer - news item 121 of 130
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Interactions of HPV Capsids with Cell-surface Receptor [Protein Structure and Folding]
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High risk human papillomavirus types 16 (HPV16) and 18 (HPV18) can cause cervical cancer. Efficient infection by HPV16 and HPV18 pseudovirions requires interactions of particles with cell-surface receptor heparan sulfate oligosaccharide. To understand the virus-receptor interactions for HPV infection, we determined the crystal structures of HPV16 and HPV18 capsids bound...
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RSS Source: Med Worm - Cervical Cancer Thu, 20 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 122 of 130
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Molecular mechanisms of epidermal growth factor receptor overexpression in patients with cervical cancer
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Authors: Marlies Schrevel, Arko Gorter, Sandra M Kolkman-Uljee, J Baptist M Z Trimbos, Gert Jan Fleuren & Ekaterina S Jordanova (Source: Modern Pathology AOP)
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RSS Source: Med Worm - Cervical Cancer Thu, 20 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 123 of 130
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'Patchwork' Of Gene Faults Could Help Predict Cervical Cancer Drug Success
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Cancer Research UK scientists have discovered that cervical cancer patients who have a mixture of different genetic faults in their tumour at the start of treatment may be more likely to relapse, according to a study published in the British Journal of Cancer. Scientists believe this may be because this...
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RSS Source: Med Worm - Cervical Cancer Thu, 20 Jan 2011 12:00:00 pm
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Cervical Cancer - news item 124 of 130
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Survivors' Stories, Statistics, Highlight Importance Of Cervical Cancer Elimination Goal
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Patricia Gregory of Cary was only 24 years old when she was diagnosed with cervical cancer. Now a mother of an 11-year-old daughter, she considers herself blessed to have a child, as cervical cancer can make women unable to bear children. Marie Miranda, who was diagnosed at age 28, underwent...
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RSS Source: Med Worm - Cervical Cancer Thu, 20 Jan 2011 11:00:00 am
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Cervical Cancer - news item 125 of 130
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Fertility-sparing surgery for young women with early-stage cervical cancer.
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Authors: Smith J, Ghaem-Maghami S, McIndoe A, Farthing A, Mason P, Ungar L, Del Priore G PMID: 21226829 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
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RSS Source: Med Worm - Cervical Cancer Thu, 20 Jan 2011 10:30:57 am
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Cervical Cancer - news item 126 of 130
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Autocrine/paracrine erythropoietin signalling promotes JAK/STATâ€dependent proliferation of human cervical cancer cells
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AbstractErythropoietin (Epo) regulates erythropoiesis by binding to its receptor (EpoR) and promoting cell proliferation, differentiation, and inhibition of apoptosis. Epo is widely used to treat cervical cancerâ€related anaemia. However, there are data suggesting that administration of Epo is associated with an increment in recurrence rate, and decreased diseaseâ€free and overall...
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RSS Source: Med Worm - Cervical Cancer Wed, 19 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 127 of 130
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Implication of human nonmetastatic clone 23 type 1 and its downstream gene lipocalin 2 in metastasis and patient's survival of cancer of uterine cervix
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In conclusion, when nm23â€H1 gene is knocked down in SiHa cervical cancer cells, cells migration and invasion decrease through elevated expression of lipocalin 2. Cervical cancer patients with positive nm23â€H1 and negative lipocalin 2 should be followed and treated intensely. (Source: International Journal of Cancer)
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RSS Source: Med Worm - Cervical Cancer Wed, 19 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 128 of 130
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Distribution of high and low risk HPV types by cytological status: a population based study from Italy
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Conclusions: mass vaccination with bivalent or quadrivalent HPV vaccine would modestly impact on prevalence of abnormal Pap-test in screening. (Source: Infectious Agents and Cancer) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Cervical Cancer Wed, 19 Jan 2011 11:00:00 pm
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Cervical Cancer - news item 129 of 130
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Prognostic Cell Biological Markers in Cervical Cancer Patients Primarily Treated With (Chemo)radiation: A Systematic Review
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In conclusion, EGFR signaling is associated with poor prognosis and response to therapy in cervical cancer patients primarily treated with (chemo)radiation, whereas markers involved in angiogenesis and hypoxia, COX-2, and serum SCC-ag levels are associated with a poor prognosis. Therefore, targeting these pathways in combination with chemoradiation may improve survival...
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RSS Source: Med Worm - Cervical Cancer Wed, 19 Jan 2011 6:52:19 pm
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Cervical Cancer - news item 130 of 130
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The vaginal radical trachelectomy: An update of a series of 125 cases and 106 pregnancies.
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CONCLUSION: VRT is an oncologically safe procedure in well-selected patients with early-stage disease. Lesion size >2cm appears to be associated with a higher risk of recurrence and a higher risk of abandoning the planned VRT. Fertility and obstetrical outcomes post VRT are excellent. PMID: 21255824 [PubMed - as supplied by...
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RSS Source: Med Worm - Cervical Cancer Tue, 18 Jan 2011 11:00:00 pm
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