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Mon, 07 Mar 2011 at 20:35:59

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Deep Vein Thrombosis (DVT) - news item 1 of 148

Every five minutes someone dies from a blood clot or deep vein thrombosis

Each year between 100,000-180,000 Americans die as the result of pulmonary embolism, a complication from blood clots in the lungs. The Vascular Disease Foundation urges Americans, especially women, to learn about the risks of venous blood clots to help prevent these deaths. While men and women are at equal risk,...

RSS Source:   Med Worm - Deep Vein Thrombosis Sat, 5 Mar 2011 4:00:00 am

Deep Vein Thrombosis (DVT) - news item 2 of 148

Every Five Minutes Someone Dies From A Blood Clot Or Deep Vein Thrombosis (DVT)

Each year between 100,000-180,000 Americans die as the result of pulmonary embolism, a complication from blood clots in the lungs. The Vascular Disease Foundation urges Americans, especially women, to learn about the risks of venous blood clots to help prevent these deaths. While men and women are at equal risk,...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 4 Mar 2011 11:00:00 am

Deep Vein Thrombosis (DVT) - news item 3 of 148

Review: Upper extremity DVT

Source: N Engl J Med Area: News This Clinical Practice review covers deep-vein thrombosis (DVT) affecting the upper extremities. As usual, the author presents an example patient and uses this case to discuss the management based on current published evidence. The patient presented is a middle-aged lady who presents with...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 2 Mar 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 4 of 148

Deep-Vein Thrombosis of the Upper Extremities

New England Journal of Medicine, Volume 364, Issue 9, Page 861-869, March 2011. (Source: New England Journal of Medicine)

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 2 Mar 2011 9:00:16 pm

Deep Vein Thrombosis (DVT) - news item 5 of 148

Society For Vascular Medicine Features Case Study, Special Section On Deep Vein Thrombosis During DVT Awareness Month

As many as 600,000 Americans will experience a deep vein thrombosis (DVT) or pulmonary embolism this year. The Society for Vascular Medicine (SVM) is working to increase awareness of DVT, its diagnosis and treatment. A deep vein thrombosis (DVT) is a blood clot that forms in one of the deep...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 2 Mar 2011 9:00:00 am

Deep Vein Thrombosis (DVT) - news item 6 of 148

Promising Norwegian Treatment For Blood Clots

Blood clots in the leg (deep vein thrombosis DVT) occur commonly. In one-half of the cases, the blood clot will break loose and travel through the bloodstream to the lungs which may be life-threatening. Current treatment stops the blood clot from moving, but does not prevent permanent damage to the...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 1 Mar 2011 8:00:00 am

Deep Vein Thrombosis (DVT) - news item 7 of 148

The role of thrombolysis in the clinical management of deep vein thrombosis.

Authors: Popuri RK, Vedantham S The cornerstones of current management of deep vein thrombosis (DVT) are the routine use of anticoagulant therapy, graduated elastic compression stockings, and early ambulation. Thrombolytic therapy was previously reserved only for patients with life-, limb-, or organ-threatening complications. However, the postthrombotic syndrome has been increasingly...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 28 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 8 of 148

Hypercoagulability and hypofibrinolysis and risk of deep vein thrombosis and splanchnic vein thrombosis: similarities and differences.

Authors: Smalberg JH, Kruip MJ, Janssen HL, Rijken DC, Leebeek FW, de Maat MP In this review, we provide an overview of the risk factors for venous thromboembolism, focusing on hypercoagulability and hypofibrinolysis. In the first part of this review, we discuss the risk factors for commonly occurring venous thrombosis,...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 28 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 9 of 148

Leukocytes and the natural history of deep vein thrombosis: current concepts and future directions.

Authors: Saha P, Humphries J, Modarai B, Mattock K, Waltham M, Evans CE, Ahmad A, Patel AS, Premaratne S, Lyons OT, Smith A Observational studies have shown that inflammatory cells accumulate within the thrombus and surrounding vein wall during the natural history of venous thrombosis. More recent studies have begun...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 28 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 10 of 148

New gene variants associated with venous thrombosis: a replication study in White and Black Americans

Conclusions: Our study supports the finding that genetic variants in the F11 gene are risk factors for venous thrombosis among both Whites and Blacks, although the findings in Blacks require confirmation. A meta‐analysis of five case†control studies indicates that rs2227589 in the SERPINC1 gene, rs13146272 in the CYP4V2 gene and...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 28 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 11 of 148

Evaluation of performance including influence by interfering substances of the innovance d-dimer assay on the sysmex coagulation analyzer.

In conclusion, the Innovance D-dimer assay is suitable for monitoring D-dimer concentrations in various clinical conditions and should be useful in clinical laboratories. PMID: 21325250 [PubMed - in process] (Source: Annals of Clinical and Laboratory Science)

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 28 Feb 2011 10:45:06 pm

Deep Vein Thrombosis (DVT) - news item 12 of 148

A Heparin Binding Site Arg79Cys Missense Mutation in the SERPINC1 Gene in a Korean Patient with Hereditary Antithrombin Deficiency.

We describe a case of heparin binding site Arg79Cys mutation in the gene encoding antithrombin, SERPINC1, in a Korean patient with hereditary antithrombin (AT) deficiency. The patient was a 34-year-old Korean man who presented with deep vein thrombosis (DVT) in his right leg without precipitating factors. On outpatient evaluation, coagulation...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 28 Feb 2011 10:45:06 pm

Deep Vein Thrombosis (DVT) - news item 13 of 148

D-dimer and residual vein obstruction as risk factors for recurrence during and after anticoagulation withdrawal in patients with a first episode of provoked deep-vein thrombosis.

In conclusion, an abnormal D-dimer during vitamin K antagonist (VKA) treatment or at one month after VKA withdrawal is a risk factor for recurrence in patients with provoked DVT, while RVO at the time of anticoagulation withdrawal is not. PMID: 21359409 [PubMed - as supplied by publisher] (Source: Thrombosis and...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 27 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 14 of 148

Mortality and morbidity associated with simultaneous bilateral or staged bilateral total knee arthroplasty: a meta-analysis

Conclusion Compared with staged bilateral TKA, simultaneous bilateral TKA might carry a higher potential risk of postoperative complications. Patients should be aware of this information when deciding whether to proceed with simultaneous bilateral TKA. The poor quality of the studies calls into question the robustness of the analyses. Content Type...

RSS Source:   Med Worm - Deep Vein Thrombosis Sat, 26 Feb 2011 8:40:43 pm

Deep Vein Thrombosis (DVT) - news item 15 of 148

Extended-duration rivaroxaban thromboprophylaxis in acutely ill medical patients: MAGELLAN study protocol

Abstract Patients with acute medical illnesses are at increased risk of venous thromboembolism (VTE), a significant cause of morbidity and mortality. Thromboprophylaxis is recommended in these patients but questions remain regarding the optimal duration of therapy. The aim of this study is to determine whether oral rivaroxaban is non-inferior to...

RSS Source:   Med Worm - Deep Vein Thrombosis Sat, 26 Feb 2011 2:17:30 pm

Deep Vein Thrombosis (DVT) - news item 16 of 148

People with Bowel Disease at Higher Risk of Blood Clot in Lungs, Legs

Study finds they're twice as likely to develop the dangerous mass as those without IBD Source: HealthDay Related MedlinePlus Pages: Deep Vein Thrombosis, Pulmonary Embolism, Ulcerative Colitis (Source: MedlinePlus Health News)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 22 Feb 2011 1:00:00 pm

Deep Vein Thrombosis (DVT) - news item 17 of 148

Inflammatory Bowel Disease More Than Doubles Potentially Fatal Blood Clot Risk

Inflammatory bowel disease more than doubles the risk of a potentially fatal blood clot in the legs or lungs (VTE), reveals research published online in the journal Gut. Inflammatory bowel disease is an umbrella term used to include Crohn's disease and ulcerative colitis. Venous thromboembolism (VTE), which includes deep vein...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 22 Feb 2011 7:00:00 am

Deep Vein Thrombosis (DVT) - news item 18 of 148

Extended anticoagulation for unprovoked venous thromboembolism: a majority of patients should be treated

Abstract About half of patients with a first unprovoked proximal deep vein thrombosis (DVT) or pulmonary embolism (PE) will have a recurrent venous thromboembolism (VTE) within 10 years if they stop treatment, and randomized trials have shown clear benefit from extended anticoagulant therapy in these patients. Although the risk of...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 18 Feb 2011 5:52:40 am

Deep Vein Thrombosis (DVT) - news item 19 of 148

Residual vein obstruction as a predictor for recurrent thromboembolic events after a first unprovoked episode: data from the REVERSE cohort study

Conclusion: In our study, the presence of RVO at the time of OAT withdrawal was not associated with a statistically significant higher risk of recurrent VTE. RVO assessment may not be useful to guide duration of anticoagulation. (Source: Journal of Thrombosis and Haemostasis)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 15 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 20 of 148

Venous Health Systems Receives FDA Clearance to Commercialize Fully Portable Pneumatic Compression System to Treat Vascular Insufficiency

PORTOLA VALLEY, Calif.--(Healthcare Sales & Marketing Network)-- Venous Health Systems, Inc., a developer of solutions for treating vascular insufficiency by enhancing blood circulation, today announced that it has received 510(k) clearance from the Food &... Devices, FDAVenous Health Systems, Vasculaire, vascular insufficiency, Deep Vein Thrombosis (Source: HSMN NewsFeed) MedWorm Message:...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 15 Feb 2011 6:42:22 pm

Deep Vein Thrombosis (DVT) - news item 21 of 148

Merino wool graduated compression stocking increases lower limb venous blood flow: A randomized controlled trial.

CONCLUSION: The novel merino wool double-layer, below-knee graduated compression stocking increases lower limb venous blood flow during prolonged seated immobility. Its use is likely to reduce the risk of DVT and PE in situations of prolonged seated immobility, such as long-distance air travel. The reduction in lower limb swelling associated...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 13 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 22 of 148

Von Willebrand Factor critical for DVT formation

Von Willebrand Factor-mediated platelet adhesion is essential for flow reduction-induced deep vein thrombosis in mouse models, study findings indicate. (Source: MedWire News - Thrombosis)

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 11 Feb 2011 10:06:47 pm

Deep Vein Thrombosis (DVT) - news item 23 of 148

FondaKIDS: A prospective pharmacokinetic and safety study of fondaparinux in children between 1 and 18 years of age

ConclusionDosing of fondaparinux at 0.1 mg/kg once daily in children resulted in PK profiles comparable to those in adults receiving standard dosing. Fondaparinux can be considered an attractive alternative to LMWH given its once‐daily dosing, acceptable safety data, and other favorable properties. Pediatr Blood Cancer © 2011 Wiley‐Liss, Inc. (Source: Pediatric...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 10 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 24 of 148

Comparing the Diagnostic Performance of 2 Clinical Decision Rules to Rule Out Deep Vein Thrombosis in Primary Care Patients

A new clinical decision rule for clinical assessment of patients with suspected deep vein thrombosis has been proposed. Can it replace the commonly used Wells rule? Annals of Family Medicine (Source: Medscape Today Headlines)

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 10 Feb 2011 3:00:00 am

Deep Vein Thrombosis (DVT) - news item 25 of 148

Anti-PF4/heparin antibodies linked to DVT after orthopedic surgery

Patients who develop immunoglobulin G antibodies to the platelet factor 4/heparin complex following total knee or hip arthroplasty have an increased risk for deep vein thrombosis, Japanese researchers report. (Source: MedWire News - Thrombosis) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 9 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 26 of 148

The value of 64-detector row computed tomography for the exclusion of pulmonary embolism.

Authors: Pesavento R, de Conti G, Minotto I, Filippi L, Mongiat M, de Faveri D, Maurizi F, Dalla Valle F, Piovella C, Pagnan A, Prandoni P, Recently, a diagnostic strategy using a clinical decision rule, D-dimer testing and spiral computed tomography (CT) was found to be effective in the evaluation...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 7 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 27 of 148

Heparin-induced thrombocytopenia and warfarin-induced skin necrosis: case report

É relatado um caso de trombocitopenia induzida por heparina complicada, com necrose cutânea induzida por varfarina em paciente de 74 anos, sexo feminino, internada com diagnóstico de fratura do colo do fêmur, trombose venosa profunda e tromboembolismo pulmonar. A necrose cutânea induzida por varfarina é uma complicação rara da terapia...

RSS Source:   Med Worm - Deep Vein Thrombosis Sat, 5 Feb 2011 3:27:02 pm

Deep Vein Thrombosis (DVT) - news item 28 of 148

Prospective study on the efficacies of fondaparinux and enoxaparin in preventing venous thromboembolism after hip fracture surgery

Conclusions We concluded that FPX was the superior agent for preventing VTE after HFS. However, patients receiving FPX should be monitored for bleeding. Content Type Journal ArticlePages 1-7DOI 10.1007/s00776-010-0011-5Authors Satoshi Sasaki, Department of Orthopedic Surgery, Yuri-Kumiai General Hospital, 38 Yago Kawaguchi, Yurihonjo, 015-8511 JapanNaohisa Miyakoshi, Department of Orthopedic Surgery, Akita...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 4 Feb 2011 2:34:14 am

Deep Vein Thrombosis (DVT) - news item 29 of 148

Bilateral Orbital Haematomas in an Anticoagulated Patient with Severe H1N1 Influenza.

Authors: Mansurali N, Maclaren G, Sundar G A previously healthy woman was admitted to the intensive care unit (ICU) with severe H1N1 influenza. She had prolonged hospital stay due to multiple complications of critical illness, including pelvic deep vein thrombosis (DVT), which was treated with subcutaneous enoxaparin. The patient was...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 2 Feb 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 30 of 148

Silent Pulmonary Embolism in Patients with Deep Vein Thrombosis: A Systematic Review: Stein PD, Matta F, Musani MH, Diaczok B. Am J Med 2010;123:426†31.

This study combined data from 28 previous studies on silent PEs to estimate the incidence of PEs among patients with diagnosed DVTs. The authors of this study found that>30% of patients with DVTs without pulmonary complaints had positive diagnostic studies for PE. Proximal DVTs carried a higher likelihood of the...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 31 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 31 of 148

Is routine chemical thromboprophylaxis after total hip replacement really necessary in a Japanese population?

Authors: Yokote R, Matsubara M, Hirasawa N, Hagio S, Ishii K, Takata C Prophylaxis against venous thromboembolism after elective total hip replacement is routinely recommended. Our preference has been to use mechanical prophylaxis without anticoagulant drugs. A randomised controlled trial was performed to evaluate whether the incidence of post-operative venous...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 31 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 32 of 148

Air travel and venous thromboembolism: Minimizing the risk

For those traveling on long flights, the risk of deep vein thrombosis or pulmonary embolism, generally referred to as venous thromboembolism (VTE), is real and dangerous if left unrecognized or untreated. The goal of this publication is to provide an overview of how best to prevent VTE during travel, and...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 31 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 33 of 148

Single intravenous administration of TB‐402 for the prophylaxis of venous thromboembolism after total knee replacement: a dose‐escalating, randomised, controlled trial

Conclusions: TB‐402, as a single postoperative administration, was associated with a lower rate of VTE in all doses tested, compared to enoxaparin. The incidence of major and clinically relevant non‐major bleeding was similar to enoxaparin 40 mg for TB‐402 0.3 and 0.6 mg/kg. (Source: Journal of Thrombosis and Haemostasis) MedWorm...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 31 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 34 of 148

A Systematic Review of Percutaneous Mechanical Thrombectomy in the Treatment of Deep Venous Thrombosis.

CONCLUSION: PMT appears feasible and safe, though the level of evidence available is poor. Major RCTs and registry data are required to determine the economic and clinical benefit of various devices used alone or in combination, for differing thrombus characteristics and clinical scenarios. Until these data are available there is...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 30 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 35 of 148

Deep Vein Thrombosis and Pulmonary Embolism in Hospitalized Patients with Cirrhosis: A Nationwide Analysis

Conclusions Despite the often-associated coagulopathy, VTE contributes to a significant burden in patients with cirrhosis. Efforts directed at VTE prevention in this cohort, especially high-risk patients, should be actively pursued. Content Type Journal ArticlePages 1-8DOI 10.1007/s10620-011-1582-5Authors Muhammad Ali, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USAAshwin N....

RSS Source:   Med Worm - Deep Vein Thrombosis Sat, 29 Jan 2011 4:19:13 pm

Deep Vein Thrombosis (DVT) - news item 36 of 148

High percentage of non‐diagnostic compression ultrasonography results and the diagnosis of ipsilateral recurrent proximal deep vein thrombosis: reply to a rebuttal

See also Tan M, Velthuis SI, Westerbeek RE, van Rooden CJ, van der Meer FJ, Huisman MV. High percentage of non‐diagnostic compression ultrasonography results and the diagnosis of ipsilateral recurrent proximal deep vein thrombosis. J Thromb Haemost 2010; 8: 848†50; Hassen S, Barrellier MT, Seinturier C, Bosson JL, Genty...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 27 Jan 2011 3:16:53 pm

Deep Vein Thrombosis (DVT) - news item 37 of 148

High percentage of non‐diagnostic compression ultrasonography results and the diagnosis of ipsilateral recurrent proximal deep vein thrombosis: a rebuttal

See also Tan M, Velthuis SI, Westerbeek RE, van Rooden CJ, van der Meer FJ, Huisman MV. High percentage of non‐diagnostic compression ultrasonography results and the diagnosis of ipsilateral recurrent proximal deep vein thrombosis. J Thromb Haemost 2010; 8: 848†50; Tan M, Huisman MV. High percentage of non‐diagnostic compression...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 27 Jan 2011 3:16:53 pm

Deep Vein Thrombosis (DVT) - news item 38 of 148

Risk factors for catheter‐related thrombosis (CRT) in cancer patients: a patient‐level data (IPD) meta‐analysis of clinical trials and prospective studies

Conclusions: CRT risk is increased with use of PICCs, previous history of DVT, subclavian venipuncture insertion technique and improper positioning of the catheter tip. These factors may be useful for risk stratifying patients to select those for thromboprophylaxis. Prospective studies are needed to validate these findings. (Source: Journal of Thrombosis and...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 27 Jan 2011 3:16:42 pm

Deep Vein Thrombosis (DVT) - news item 39 of 148

Upper Extremity Deep Vein Thrombosis: The Oft-forgotten Cousin of Venous Thromboembolic Disease

Opinion statement Upper extremity deep venous thrombosis (UEDVT) accounts for between 4% and 10% of all deep venous thromboses, and may be due to primary or secondary causes. The incidence of UEDVT is increasing, partly due to the exponential growth in the use of central venous catheters and the increasing...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 27 Jan 2011 12:08:43 am

Deep Vein Thrombosis (DVT) - news item 40 of 148

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

Deep vein thrombosis (DVT) and its complication, pulmonary embolism, are frequent causes of disability and mortality. Although blood flow disturbance is considered an important triggering factor, the mechanism of DVT initiation remains elusive. Here we show that 48-hour flow restriction in the inferior vena cava (IVC) results in the development...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 26 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 41 of 148

The North American Thrombosis Forum (NATF) Honors Hospitals That Excel In The Prevention Of Deep Vein Thrombosis (DVT)

The North American Thrombosis Forum, in coordination with Eisai Inc., announced that four hospitals have been selected as recipients of the 2010 DVTeamCare Hospital Award. The award, now in its second year, was established by Eisai Inc. to recognize hospitals that have made a significant commitment to preventing Deep Vein...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 25 Jan 2011 12:00:00 pm

Deep Vein Thrombosis (DVT) - news item 42 of 148

Siemens Receives FDA Clearance For Its Innovance D-Dimer Test To Exclude Deep Vein Thrombosis

Siemens Healthcare Diagnostics INNOVANCE® D-Dimer blood test has been cleared by the FDA to exclude deep vein thrombosis (DVT) and pulmonary embolism (PE), in patients where a physicians pretest probability assessment (PTP) indicates a non-high probability of embolism. The expanded use of this test helps physicians provide more timely patient...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 25 Jan 2011 10:00:00 am

Deep Vein Thrombosis (DVT) - news item 43 of 148

Symptomatic Venous Thromboembolism in Asian Colorectal Cancer Surgery Patients

Conclusions The incidences of symptomatic DVT and PE were found to be not low in Asian colorectal cancer surgery patients compared with Western countries. The risk factors for VTE were a history of VTE, pre-existing cardiovascular disease, postoperative complications, advanced cancer stage, and postoperative immobilization. Thromboprophylaxis should be strongly considered...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 25 Jan 2011 5:49:48 am

Deep Vein Thrombosis (DVT) - news item 44 of 148

IgG-class anti-PF4/heparin antibodies and symptomatic DVT in orthopedic surgery patients receiving different anti-thromboembolic prophylaxis therapeutics

Conclusion: Our findings show that the seroconversion of IgG-class anti-PF4/heparin antibodies differed with various anti-thrombotic prophylaxis therapeutics and was associated with the risk of DVT in a subset of patients undergoing total joint arthroplasty (TKA and THA). (Source: BMC Musculoskeletal Disorders)

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 23 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 45 of 148

Use and wear of anti‐embolism stockings: a clinical audit of surgical patients

The objective of this study was to determine if anti‐embolism stockings are fitted and worn according to evidence‐based guidelines in surgical patients. The methodology is that an observational study was undertaken during January and February, 2010. An audit tool was constructed for the recording of information on a variety of...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 21 Jan 2011 7:40:20 pm

Deep Vein Thrombosis (DVT) - news item 46 of 148

Pharmacological Deep Vein Thrombosis Prophylaxis Does Not Lead to Hematoma Expansion in Intracerebral Hemorrhage With Intraventricular Extension.

CONCLUSIONS: Pharmacological deep venous thrombosis prophylaxis given subcutaneously in patients with ICH and/or intraventricular hemorrhage in the subacute period is generally not associated with hematoma growth. PMID: 21257826 [PubMed - as supplied by publisher] (Source: Stroke) MedWorm Message: Watch the new MedWorm demo and find out how to get all...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 20 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 47 of 148

High Frequency of Silent Pulmonary Embolism in Patients With Cryptogenic Stroke and Patent Foramen Ovale.

CONCLUSIONS: Silent PE frequently occurs in patients with cryptogenic stroke and patent foramen ovale, particularly when atrial septal aneurysm or hypermobile atrial septum are present. PMID: 21257827 [PubMed - as supplied by publisher] (Source: Stroke)

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 20 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 48 of 148

Hepatic veins as a site of clot formation following liver resection.

Authors: Buc E, Dokmak S, Zappa M, Denninger MH, Valla DC, Belghiti J, Farges O Pulmonary embolism occurs more frequently after hepatectomy than previously thought but is infrequently associated with peripheral deep vein thrombosis. In this paper, we report 2 cases of postoperative hepatic vein thrombosis after liver resection. Both...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 20 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 49 of 148

Traffic exposure and incident venous thromboembolism in the atherosclerosis risk in communities (ARIC) study

Conclusions: This first prospective study in the general population does not support an association between air pollution exposure or traffic proximity and risk of DVT. More data may be needed to clarify whether traffic or air pollution influences the risk of VTE. (Source: Journal of Thrombosis and Haemostasis)

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 20 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 50 of 148

Use of antithrombotic medications among elderly ischemic stroke patients

Source: Circulation: Cardiovascular Quality and Outcomes Area: Evidence > Medicines Management > References Background: The use of antithrombotic medications after ischaemic stroke is recommended for deep vein thrombosis prophylaxis and secondary stroke prevention. We assessed the rate of receipt of these therapies among eligible ischaemic stroke patients aged 65 years or older...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 20 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 51 of 148

Clinical Decision Rules May Safely Rule Out Deep Vein Thrombosis

Suspected DVT can safely be ruled out using either of 2 decision rules plus a point-of-care D-dimer test, reducing unnecessary referrals for compression ultrasonography. Medscape Medical News (Source: Medscape Nurses Headlines)

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 20 Jan 2011 3:53:26 pm

Deep Vein Thrombosis (DVT) - news item 52 of 148

Safety and Feasibility of Ultrasound-accelerated Catheter-directed Thrombolysis in Deep Vein Thrombosis.

CONCLUSION: US-accelerated CDT is a safe and promising treatment in patients with DVT. Residual venous obstruction should be treated by angioplasty and stent insertion to avoid early re-thrombosis. PMID: 21256773 [PubMed - as supplied by publisher] (Source: PubMed: Eur J Vasc Endovasc ...)

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 19 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 53 of 148

Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo

Hepcidin is a major regulator of iron homeostasis, and its expression in liver is regulated by iron, inflammation, and erythropoietic activity with mechanisms that involve bone morphogenetic proteins (BMPs) binding their receptors and coreceptors. Here we show that exogenous heparin strongly inhibited hepcidin expression in hepatic HepG2 cells at pharmacologic...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 19 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 54 of 148

'Selective strategy' recommended for CT scans in emergency departments

(University of Cincinnati Academic Health Center) Emergency medicine researchers with the University of Cincinnati are proposing a new strategy for diagnosing a common but dangerous condition in the emergency room. With rates of computed tomography angiography (CTA) on the rise, they want to curb blanket use of the test in...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 18 Jan 2011 4:00:00 am

Deep Vein Thrombosis (DVT) - news item 55 of 148

An unexpected case of venous and pulmonary thrombo-embolism in a patient treated with thalidomide for refractory erythema nodosum leprosum: a case report

We report a case of deep vein thrombosis (DVT) and pulmonary embolism (PE) following thalidomide use in a patient with erythema nodosum leprosum (ENL) reaction who was concurrently treated with prednisolone, as well as a review of relevant literature. (Source: Thrombosis Journal) MedWorm Message: Watch the new MedWorm demo and...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 17 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 56 of 148

Heparin-induced thrombocytopenia: what a vascular surgeon needs to know.

This article aims in a comprehensive review of the literature for newly emerged data in the pathogenesis, diagnosis and management of heparin-induced thrombocytopenia. PMID: 21224814 [PubMed - in process] (Source: The Journal of Cardiovascular Surgery)

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 14 Jan 2011 7:45:39 am

Deep Vein Thrombosis (DVT) - news item 57 of 148

New gene variants associated with venous thrombosis †a replication study in United States whites and blacks

Conclusions: Our study supports the finding that genetic variants in the F11 gene are risk factors for venous thrombosis both among Whites and Blacks, although the findings in Blacks require confirmation. A meta‐analysis of 5 case‐control studies indicates that rs2227589 in the SERPINC1 gene, rs13146272 in the CYP4V2 gene, and rs1613662...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 12 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 58 of 148

Venous giant post-thrombotic chronic ulcer: successful treatment with Bosentan.

CONCLUSION: Treatment with Bosentan has been successful in the treatment of this case of refractory chronic venous ulcer. PMID: 21228354 [PubMed - as supplied by publisher] (Source: Phlebology)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 11 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 59 of 148

Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II). A randomised, double-blind, non-inferiority trial.

Authors: Eriksson BI, Dahl OE, Huo MH, Kurth AA, Hantel S, Hermansson K, Schnee JM, Friedman RJ, This trial compared the efficacy and safety of oral dabigatran, a direct thrombin inhibitor, versus subcutaneous enoxaparin for extended thromboprophylaxis in patients undergoing total hip arthroplasty. A total of 2,055 patients were randomised...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 11 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 60 of 148

Acetabular fractures

Orthopedic Trauma Directions 2010; 8: 1-9DOI: 10.1055/s-0030-1267057SummaryThree retrospective cohort studies of patients with acetabular fractures examined the impact of morbid obesity on patient complications after operative fracture fixation. The morbidly obese patient appears to have an elevated risk of more perioperative blood loss and of wound infection. While a higher...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 10 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 61 of 148

Percutaneous Mechanical and Pharmacomechanical Thrombolysis for Occlusive Deep Vein Thrombosis of the Proximal Limb in Adolescent Subjects: Findings from an Institution-based Prospective Inception Cohort Study of Pediatric Venous Thromboembolism

Conclusions: This experience provides preliminary evidence that PMT/PPMT with adjunctive CDTI can be used safely and effectively in adolescent subjects with DVT at high risk for PTS. (Source: Journal of Vascular and Interventional Radiology : JVIR)

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 9 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 62 of 148

Risk of venous thromboembolism in people admitted to hospital with selected immune-mediated diseases: record-linkage study

Conclusions: People admitted to hospital with immune-mediated diseases may be at an increased risk of subsequent VTE. Our findings need independent confirmation or refutation; but, if confirmed, there may be a role for thromboprophylaxis in some patients with these diseases. (Source: BMC Medicine)

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 9 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 63 of 148

Immune Disorders May Raise Blood Clot Risk in Hospitalized Patients

Those with conditions such as lupus appear more vulnerable, study suggests Source: HealthDay Related MedlinePlus Pages: Deep Vein Thrombosis, Immune System and Disorders, Pulmonary Embolism (Source: MedlinePlus Health News)

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 9 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 64 of 148

Batroxobin Mobilizes Circulating Endothelial Progenitor Cells in Patients With Deep Vein Thrombosis

In this study, 15 patients with deep vein thrombosis (DVT) achieved successful limb salvage after the administration of batroxobin. We found that the levels of CD34+, CD31+, CD34+/CD31+, and vascular endothelial cadherin (VE-cadherin+) cells had increased in the peripheral blood of patients at 7 days and 14 days after treatment....

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 9 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 65 of 148

Rivaroxaban Submitted For EU Marketing Authorisation

Bayer has submitted an application for marketing authorisation to the European Medicines Agency (EMA) for the oral anticoagulant rivaroxaban in stroke prevention in patients with non-valvular atrial fibrillation, as well as for the treatment of deep vein thrombosis (DVT) and prevention of recurrent DVT and pulmonary embolism (PE). Rivaroxaban is...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 9 Jan 2011 7:00:00 am

Deep Vein Thrombosis (DVT) - news item 66 of 148

Effects of Delayed Hip Fracture Surgery on Mortality and Morbidity in Elderly Patients.

CONCLUSIONS: A 1-week delay in the surgical treatment of elderly patients with hip fractures did not increase the mortality rate or prolong the period of recovery but did increase the incidence of postoperative complications. Our experience suggests elderly patients with hip fractures should be operated on as soon as their...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 5 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 67 of 148

Unexpected outcome from Trousseau syndrome

Conclusions: This case provides new evidence for the presentation of superficial thrombophlebitis in early gastric carcinoma and the potential for curative surgery in such instances. A high index of suspicion and a prompt diagnostic workup are essential for timely planning and execution of surgery in these early albeit rare presentations. (...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 5 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 68 of 148

Horizon scanning: License extension application filed in EU for use of rivaroxaban for stroke prevention in AF patients and further VTE indications

Source: The pharmaletter Area: News Bayer has submitted an application to the European Medicines Agency to extend the license of rivaroxaban to include stroke prevention in patients with atrial fibrillation, and the treatment of deep vein thrombosis (DVT) and prevention of recurrent DVT and pulmonary embolism. (Source: NeLM - News)...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 5 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 69 of 148

Bayer’s Rivaroxaban Submitted for EU Marketing Authorisation in Stroke Prevention in Patients with Atrial Fibrillation as well as for the Treatment of Deep Vein Thrombosis (DVT) and Prevention of Recurrent DVT and Pulmonary Embolism (PE)

Submission in Stroke Prevention in Patients with Atrial Fibrillation (AF) based on positive results of ROCKET AF trial in more than 14,000 patients / Submission in Treatment of DVT and Prevention of Recurrent DVT and PE based on positive results of EINSTEIN-DVT and EINSTEIN-Extension clinical studies in more than 4,500 patients (...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 5 Jan 2011 8:15:00 am

Deep Vein Thrombosis (DVT) - news item 70 of 148

05.01.11: For use outside the U.S. only

Bayer's Rivaroxaban Submitted for EU Marketing Authorisation in Stroke Prevention in Patients with Atrial Fibrillation as well as for the Treatment of Deep Vein Thrombosis (DVT) and Prevention of Recurrent DVT and Pulmonary Embolism (PE)Submission in Stroke Prevention in Patients with Atrial Fibrillation (AF) based on positive results of ROCKET...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 5 Jan 2011 7:15:10 am

Deep Vein Thrombosis (DVT) - news item 71 of 148

The ABC's of Stroke Complications

Semin Neurol 2010; 30: 501-510DOI: 10.1055/s-0030-1268863ABSTRACTStroke is the third leading cause of death in the United States, with more than 140,000 deaths per year. Complications related to stroke resulting in morbidity and mortality are very common and may result from cerebral and extracerebral causes. Cerebral causes include cerebral edema, hemorrhagic...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 3 Jan 2011 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 72 of 148

Systematic review and meta-analysis of the use of tranexamic acid in total hip replacement.

We report a systematic review and meta-analysis of published randomised controlled trials evaluating the efficacy of tranexamic acid (TXA) in reducing blood loss and transfusion in total hip replacement (THR). The data were evaluated using the generic evaluation tool designed by the Cochrane Bone, Joint and Muscle Trauma Group. We...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 31 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 73 of 148

Deep vein thrombosis after total knee arthroplasty in asian patients without prophylactic anticoagulation.

This article presents a prospective study evaluating the incidence of DVT in 724 consecutive Taiwanese patients who underwent TKA without prophylactic anticoagulation therapy. Of these, 328 patients (45.3%) showed positive Homan's sign with calf swelling >3 cm. Ultrasonographic examination revealed the overall incidence of DVT to be 8.6% (62/724). The...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 31 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 74 of 148

Pediatric American College of Surgeons National Surgical Quality Improvement Program: feasibility of a novel, prospective assessment of surgical outcomes

This study reports initiation of an ACS NSQIP Pediatric at 4 children's hospitals.Methods: From October 2008 to June 2009, 121 data variables were prospectively collected for 3315 patients, including 30-day outcomes and tailoring the ACS NSQIP methodology to children's surgical specialties.Results: Three hundred seven postoperative complications/occurrences were detected in 231...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 31 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 75 of 148

Prevention and management of ovarian hyperstimulation syndrome

Abstract: Ovarian hyperstimulation syndrome (OHSS) is considered as one of the significant complications of assisted conception. Its presentation may vary in severity with the mild form affecting about 33% and the more severe forms seen in around 3†8% of in-vitro fertilization (IVF) cycles. Exact aetiology of OHSS is unknown...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 31 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 76 of 148

[May-Thurner syndrome.]

Authors: Kecskeméthy Z, Holý J May-Thurner syndrome, a pelvic vein congenital anomaly is the consequence of compression of the left common iliacal vein by the overlying right common iliacal artery that results in an increased risk for ileofemoral deep vein thrombosis. Authors present a case of a young female with...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 31 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 77 of 148

Incidence of venous thromboembolism in Korea: from the Health Insurance Review and Assessment Service database

Conclusions: This represents the largest epidemiologic study that demonstrates a lower incidence of VTE in Asian compared with Western populations; however, it also demonstrates a yearly increasing incidence of VTE in the Korean population. (Source: Journal of Thrombosis and Haemostasis)

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 31 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 78 of 148

Study Finds No Blood Clot Risk with Hormone Patch

Women who treat menopause symptoms with hormone patches rather than pills may not have an increased risk of blood clots in the legs or lungs -- even when they have a history of such clots, a new study suggests.Source: Reuters Health Related MedlinePlus Pages: Deep Vein Thrombosis, Hormone Replacement Therapy,...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 31 Dec 2010 5:16:32 pm

Deep Vein Thrombosis (DVT) - news item 79 of 148

Determining the test characteristics of claims‐based diagnostic codes for the diagnosis of venous thromboembolism in a medical service claims database

ConclusionDiagnostic codes within a medical service claims database are relatively sensitive indicators for DVT and PE, and use of claims data for VTE research purposes can be considered. Copyright © 2010 John Wiley & Sons, Ltd. (Source: Pharmacoepidemiology and Drug Safety) MedWorm Message: Watch the new MedWorm demo and find...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 30 Dec 2010 11:01:02 pm

Deep Vein Thrombosis (DVT) - news item 80 of 148

Evaluation of venous thromboembolism risk following hospitalization

Conclusions: A strong association exists between outpatient VTE diagnosis and hospitalization and gaps in pharmacologic prophylaxis utilization during hospitalization are evident. Content Type Journal ArticleDOI 10.1007/s11239-010-0542-9Authors Sheryl J. Herner, Pharmacy Department, Kaiser Permanente Colorado, Denver, CO USADwight C. Paulson, Pharmacy Department, Kaiser Permanente Colorado, Lafeyette, CO USAThomas Delate, School of...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 30 Dec 2010 5:04:07 pm

Deep Vein Thrombosis (DVT) - news item 81 of 148

Mode of Thrombolytic Therapy and Residual Obstruction do not Affect Valve Function

Successful catheter-directed thrombolysis (CDT) for iliofemoral deep vein thrombosis (IFDVT) reduces post-thrombotic morbidity and is suggested by the American College of Chest Physicians for treatment of patients of IFDVT. Pharmacomechanical thrombolysis (PMT) is also suggested to shorten the treatment times and reduce the dose of plasminogen activator. However, there is...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 28 Dec 2010 11:07:25 pm

Deep Vein Thrombosis (DVT) - news item 82 of 148

Patient Characteristics, Referral Patterns and Associated Risk Factors in Patients Referred to an Outpatient Vascular Laboratory to Rule out Deep Venous Thrombosis

Previous studies utilizing national or regional data demonstrated that a significant proportion of deep vein thrombosis (DVT) is diagnosed in the outpatient setting. Little is known, however, about patient characteristics, referral patterns, and percentage of positive DVT in patients referred to outpatient vascular laboratories. The study objective was to examine...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 28 Dec 2010 11:07:25 pm

Deep Vein Thrombosis (DVT) - news item 83 of 148

Postoperative Deep Vein Thrombosis in Total Knee or Hip Replacement Operation is Associated with Preoperative Increased Calf Muscle Deoxygenation

To assess whether preoperative calf muscle deoxygenated hemoglobin (HHb) level during light-intensity exercise is useful for identifying patients at risk of developing postoperative deep vein thrombosis (DVT). (Source: Journal of Vascular Surgery)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 28 Dec 2010 11:07:25 pm

Deep Vein Thrombosis (DVT) - news item 84 of 148

The Need for an Intersociety Consensus Guideline for Venous Ulcer

Due to their recurrence and prolonged healing time, venous ulcers (VU) consume considerable resources in healthcare systems†up to 1% of healthcare budgets in some industrialized countries. Best practice guidelines (GLs) incorporate evidence-based diagnostic and therapeutic recommendations in a cost-effective manner and have been associated with improved and effective outcomes...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 28 Dec 2010 11:07:24 pm

Deep Vein Thrombosis (DVT) - news item 85 of 148

Catheter-Directed Thrombolysis of Iliofemoral Deep Vein Thrombosis Reduces Deep Vein Thrombosis Recurrence

Iliofemoral deep vein thrombosis (DVT) is a result of a major thrombotic stimulus that results in substantial postthrombotic morbidity in patients treated with anticoagulation alone. It has been shown that iliofemoral DVT is a powerful and independent risk factor for recurrent thromboembolism. Furthermore, recurrent DVT escalates postthrombotic morbidity, since recurrent...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 28 Dec 2010 11:07:23 pm

Deep Vein Thrombosis (DVT) - news item 86 of 148

Laser Saphenous Ablations in More Than 1,000 Limbs With Long-Term Duplex Examination Follow-Up

Conclusions: On the basis of a duplex scan performed at least 1-year post-treatment, this multicenter registry confirms the safety and efficacy of the EVLA procedure in the treatment of GSV and SSV reflux. Considering the continued failure rate documented in the present study, an annual follow-up by duplex is recommended...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 28 Dec 2010 11:04:15 pm

Deep Vein Thrombosis (DVT) - news item 87 of 148

Centrally adjudicated ultrasound not always suitable for DVT screening

Centrally adjudicated complete compression ultrasound may not be suitable to screen for asymptomatic deep vein thrombosis early after major orthopedic surgery, according to German researchers. (Source: MedWire News - Thrombosis)

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 23 Dec 2010 10:57:08 pm

Deep Vein Thrombosis (DVT) - news item 88 of 148

Inferior vena cava agenesis and deep vein thrombosis: 10 patients and review of the literature

We describe 10 consecutive patients with IVCA-associated DVT and conducted an extensive literature review to investigate the typical spectrum of IVCA-associated DVT. Among our patients (eight men and two women; mean age, 25 ± 4.5 years), DVT followed intense and unusual (major) physical activity for eight of them. DVT was...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 22 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 89 of 148

That phone call saved both our lives

MY HEALTH EXPERIENCE:I HAVE just injected myself in the thigh. Without weeping or flinching. It is Sunday, April 25th, and I am in the Rotunda Hospital in Dublin undergoing treatment for deep vein thrombosis (DVT), a blood clot that formed in my calf last week as a side effect of...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 20 Dec 2010 11:34:46 pm

Deep Vein Thrombosis (DVT) - news item 90 of 148

Venous thromboembolism and bleeding after total knee and hip arthroplasty. Findings from the Spanish National Discharge Database.

Authors: Guijarro R, Montes J, San Román C, Arcelus JI, Barillari G, Granero X, Monreal M The impact of venous thromboembolism (VTE) and bleeding in patients undergoing major joint surgery has not been thoroughly studied. The Spanish National Discharge Database during the years 2005-2006 was used to assess the frequency...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 20 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 91 of 148

Deep vein thrombosis associated with protein C and protein S deficiency: An unusual cause of acute abdomen

We report the case of a previously healthy 7‐year‐old boy with iliofemoral thrombosis due to protein C and protein S deficiencies mimicking acute abdomen. © 2010 Wiley Periodicals, Inc. J Clin Ultrasound, 2010 (Source: Journal of Clinical Ultrasound)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 14 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 92 of 148

SMC does not recommend fondaparinux sodium (Arixtra ®) for treatment of acute symptomatic spontaneous superficial-vein thrombosis of lower limbs without concomitant DVT due to non-submission

Source: Scottish Medicines Consortium (SMC) Area: Evidence > Drug Specific Reviews The Scottish Medicines Consortium (SMC) has advised that in the absence of a submission from the holder of the marketing authorisation, fondaparinux sodium 1.5mg/0.3mL solution for injection, pre-filled syringe (Arixtra ®) is not recommended within NHS Scotland for the treatment...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 14 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 93 of 148

Combinations of prognostic tools for identification of high-risk normotensive patients with acute symptomatic pulmonary embolism

Conclusions In haemodynamically stable patients with acute symptomatic PE, a combination of echocardiography (or troponin testing) and CCUS improved prognostication compared with the use of any test by itself for the identification of those at high risk of PE-related death. (Source: Thorax) MedWorm Message: Watch the new MedWorm demo and...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 12 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 94 of 148

Horizon scanning: Phase III study of edoxaban versus enoxaparin in prevention of VTE

Source: PharmaTimes Area: News PharmaTimes has reported on the results of a Phase III study comparing the investigational anticoagulant edoxaban to enoxaparin in the prevention of venous thromboembolism (VTE) following total hip replacement (THR) surgery, presented at the American Society of Haematology (ASH) annual meeting. The Phase III STARS J-V...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 12 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 95 of 148

Mechanical thrombectomy of an infected deep venous thrombosis: a novel technique of source control in sepsis

In this report, we discuss the novel use of this technique for source control in a patient with septic shock secondary to infected thrombus. (Source: British Journal of Anaesthesia)

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 9 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 96 of 148

A local increase in red blood cell aggregation can trigger deep vein thrombosis: evidence based on quantitative cellular ultrasound imaging

Conclusions: A marked increase in RBC aggregation promotes thrombosis in rabbit femoral veins, confirming a pathophysiological role of locally altered hemorheology in the onset of DVT. (Source: Journal of Thrombosis and Haemostasis)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 7 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 97 of 148

Cardiovascular and Interventional Radiological Society of Europe Commentary on the Treatment of Chronic Cerebrospinal Venous Insufficiency

Abstract Chronic cerebrospinal venous insufficiency (CCSVI) is a putative new theory that has been suggested by some to have a direct causative relation with the symptomatology associated with multiple sclerosis (MS) [1]. The core foundation of this theory is that there is abnormal venous drainage from the brain due to...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 7 Dec 2010 5:54:07 am

Deep Vein Thrombosis (DVT) - news item 98 of 148

Interobserver agreement on ultrasound diameter measurements of acute proximal and distal deep vein thrombosis: a rebuttal

(Source: Journal of Thrombosis and Haemostasis) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 6 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 99 of 148

Surgery for hip fractures: Does surgical delay affect outcomes?

Nicole Simunovic, PJ Devereaux, Mohit BhandariIndian Journal of Orthopaedics 2011 45(1):27-32Hip fractures are associated with a high rate of mortality and profound temporary and sometimes permanent impairment of quality of life. Current guidelines indicate that surgeons should perform surgery for a hip fracture within 24 hours of injury because earlier...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 6 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 100 of 148

New Blood Thinner May Help Fight Dangerous Leg Clots

Rivaroxaban appears safe, effective, study finds, although it will cost more than standard drugs Source: HealthDay Related MedlinePlus Pages: Blood Thinners, Deep Vein Thrombosis (Source: MedlinePlus Health News)

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 6 Dec 2010 10:00:00 am

Deep Vein Thrombosis (DVT) - news item 101 of 148

Interleukin-6: A Potential Target for Post-Thrombotic Syndrome

Conclusions: Neutralizing IL-6 throughout venous thrombogenesis decreased the production of CCL2, reduced monocyte recruitment, and decreased vein wall intimal thickness and fibrosis. These results suggest that IL-6 may serve as a therapeutic target to prevent the fibrotic complications seen in PTS. (Source: Annals of Vascular Surgery) MedWorm Message: Watch the...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 5 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 102 of 148

ASH: Oral Venous Thrombosis Agent Effective and Safe

Rivaroxaban, an oral factor Xa inhibitor, may provide clinical practitioners with a simple, fixed-dosed regimen for the short-term and continued treatment of deep-vein thrombosis, according to a study published online Dec. 4 in the New England Journal of Medicine to coincide with presentation at the annual meeting of the American...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 5 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 103 of 148

Review: Risk assessment for recurrent venous thrombosis

Source: Lancet Area: News This review article looks at the different approaches to assessment of risk of recurrent venous thromboembolism (VTE) in patients who have completed anticoagulation therapy for deep vein thrombosis (DVT) or pulmonary embolism (PE). The following topics are covered: . Risk factors for recurrent venous thrombosis . Clinical features ....

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 5 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 104 of 148

Oral rivaroxaban non-inferior to enoxaparin then vitamin K antagonist for DVT treatment

Source: New England Journal of Medicine Area: News Oral rivaroxaban gives similar outcomes to enoxaparin followed by a vitamin K antagonist in the treatment of patients with deep vein thrombosis (DVT), according to a controlled trial; a continuation study found that further treatment with rivaroxaban reduced DVT events compared to...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 5 Dec 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 105 of 148

HIF1α stimulates venous thrombus recanalization

Upregulation of hypoxia-inducible factor 1α enhances thrombus resolution and vein recanalization, making it a novel target for the treatment of deep vein thrombosis, UK researchers report. (Source: MedWire News - Thrombosis)

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 3 Dec 2010 5:36:27 am

Deep Vein Thrombosis (DVT) - news item 106 of 148

Can laparoscopic ileocolic resection be performed with comparable safety to open surgery for regional enteritis: data from National Surgical Quality Improvement Program.

Authors: Kirat HT, Pokala N, Vogel JD, Fazio VW, Kiran RP Laparoscopic ileocolic resection is feasible for Crohn's disease but few studies adjust for the various preoperative, intraoperative, and postoperative variables that may confound comparisons with open surgery. The aim of this study is to compare outcomes after laparoscopic (LICR)...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 30 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 107 of 148

Mechanical thromboprophylaxis for patients undergoing hip fracture surgery.

Authors: Mehta KV, Lee HC, Loh JS To evaluate the rates of deep vein thrombosis (DVT) and pulmonary embolism (PE) in hip fracture patients receiving mechanical thromboprophylaxis. PMID: 21187537 [PubMed - in process] (Source: Journal of Orthopaedic Surgery)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 30 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 108 of 148

Thrombolysis for Lower-Extremity Deep Vein Thrombosis

Elimination of the embolic potential of existing thrombus, restoration of unobstructed flow, prevention of further thrombosis, and preservation of venous valve function are the ideal goals of therapy for acute deep vein thrombosis (DVT). Meeting these goals will not only prevent pulmonary embolus, but will also minimize long-term sequelae of...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 30 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 109 of 148

C-B4-02: Determining Genetic Risk Factors for Post- Hospitalization development of Deep-Vein Thrombosis.

Conclusions: This hypothesis generating study demonstrates that there are many polymorphisms that are associated with DVT that have yet to be characterized. Categorization of associated DVT polymorphisms will involve careful interrogation of both the environmental conditions as well as genetic alleles of individuals. Genes such as PLAU, HTR2A, and Vitamin...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 30 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 110 of 148

Timing of Venous Thromboembolism After Colorectal Cancer Resection

Deep vein thrombosis (DVT) and pulmonary embolism (PE) are significant sources of postoperative morbidity and mortality and are currently major quality improvement initiatives. Mechanical and pharmacological prophylaxis is effective in preventing postoperative thromboembolic events, thromboprophylaxis is usually discontinued after discharge. We postulated that patients may still be at risk of...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 30 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 111 of 148

Predictors of the post‐thrombotic syndrome with non‐invasive venous examinations in patients 6 weeks after a first episode of deep vein thrombosis

Conclusions: PTS develops in half of all patients within 3 months, with no further increase being seen up to 2 years of follow‐up. Male sex, age over 50 years, proximal localization of the thrombus at entry, residual proximal thrombosis and superficial valvular reflux at 6 weeks seem to be the most important predictors of PTS...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 30 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 112 of 148

Is DVT prophylaxis necessary for thyroidectomy and parathyroidectomy?

Background: Recent guidelines suggest pharmacologic deep vein thrombosis (DVT) prophylaxis in all patients undergoing major surgical procedures to minimize the risk of postoperative DVT and pulmonary embolism (PE). Pharmacologic DVT prophylaxis perioperatively might increase the risk of bleeding complications. Our goal was to study the risk/benefit ratio of DVT prophylaxis...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 30 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 113 of 148

Ambulatory Percutaneous Nephrolithotomy: Initial Series

Conclusions: In highly selected patients, ambulatory PCNL is safe and feasible. More patients are needed to verify the criteria for patients undergoing the ambulatory approach. (Source: Urology)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 30 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 114 of 148

Clinical Issues†December 2010

This Month: Perioperative fire prevention recommendation changesKey words: fire safety, ECRI, Anesthesia Patient Safety Foundation, National Fire Protection Association, AORN Fire Safety Tool Kit.New relative humidity standards for health care facilitiesKey words: American Society of Healthcare Engineers humidity standards; National Fire Protection Agency humidity standards; safe environment of care; heating,...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 30 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 115 of 148

A simple checklist for preventing major complications associated with cesarean delivery.

Authors: Duff P I propose a simple, evidence-based, eight-item checklist that, if followed, should reduce the frequency of many of the most serious complications associated with cesarean delivery: endometritis, wound infection, wound disruption, thrombophlebitis, and uterine scar dehiscence in a subsequent pregnancy. The frequency of abdominal wound infections can be...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 29 Nov 2010 6:47:14 pm

Deep Vein Thrombosis (DVT) - news item 116 of 148

Thromboprophylaxis in patients with acute spinal injuries - an evidence-based analysis

This record is a structured abstract produced by CRD. The review concluded that low molecular weight heparin was more effective than unfractionated heparin for prevention of deep vein thrombosis and had fewer bleeding complications in patients with spinal cord injury. (Source: Neurological Conditions Specialist Library)

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 29 Nov 2010 9:48:53 am

Deep Vein Thrombosis (DVT) - news item 117 of 148

Targeted Exercise May Help Deep Vein Thrombosis Complications

(Ivanhoe Newswire) -- Exercising for health has never been a foreign concept, but a new pilot trial showed that a six-month exercise training program designed to increase leg strength, leg flexibility and overall fitness may improve post-thrombotic syndrome. (Source: Medical Headlines From Ivanhoe.com)

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 29 Nov 2010 4:00:00 am

Deep Vein Thrombosis (DVT) - news item 118 of 148

Factors Predicting Development of Post-thrombotic Syndrome in Patients with a First Episode of Deep Vein Thrombosis: Preliminary Report

Conclusions: Ilio-femoral DVT is associated with the development of PTS at initial presentation. By contrast, occlusion and reflux, high reflux velocity in the popliteal vein and increased NIRS-derived retention index are important time-course predictors of PTS progression. (Source: European Journal of Vascular and Endovascular Surgery)

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 28 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 119 of 148

Woman dies after being 'fobbed off' by nurse

A woman has died from deep vein thrombosis only two days after an NHS walk-in-centre nurse failed to spot her symptoms, a coroner has ruled. (Source: Nursing Times Breaking News) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 26 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 120 of 148

2010 good hospital guide

“Nineteen hospital trusts are today exposed as having alarmingly high death rates in a major report that also reveals how hundreds of people are dying needlessly because of substandard NHS care”, reported The Observer. The newspaper story is based on the annual hospital guide, published today by Dr Foster Intelligence,...

RSS Source:   Med Worm - Deep Vein Thrombosis Fri, 26 Nov 2010 10:41:00 am

Deep Vein Thrombosis (DVT) - news item 121 of 148

Inferior Vena Cava Filter Constrained by Displaced Fibrin Sheath Resulting in Failed Deployment

Institutional Review Board approval is not required for retrospective review of case material. Our patient is a 40-year-old man who suffered a major left-sided (dominant hemisphere) stroke and underwent a partial craniectomy to relieve intracranial pressure. He had a 4-F peripherally inserted central catheter (PICC) placed 4 days earlier (by...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 25 Nov 2010 10:11:22 am

Deep Vein Thrombosis (DVT) - news item 122 of 148

TROPICS 1: A Phase III, Randomized, Double-blind, Placebo-controlled Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters

Conclusions: Tenecteplase was efficacious for restoration of catheter function in these study patients with dysfunctional CVCs. (Source: Journal of Vascular and Interventional Radiology : JVIR)

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 25 Nov 2010 10:11:18 am

Deep Vein Thrombosis (DVT) - news item 123 of 148

The feasibility of catheter-directed thrombolysis for acute deep vein thrombosis: a regional perspective.

CONCLUSION: Using current eligibility criteria, only about 30% of patients with DVT appear to be suitable for CDT. PMID: 21109682 [PubMed - as supplied by publisher] (Source: Phlebology)

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 24 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 124 of 148

Physicians have differing attitudes towards DVT prophylaxis

Physicians’ understanding of deep vein thrombosis, its risk factors, and associated complications varies according to their specialty and level of training, US research shows. (Source: MedWire News - Thrombosis) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 24 Nov 2010 11:52:59 am

Deep Vein Thrombosis (DVT) - news item 125 of 148

NHS puts millions at 'risk of deep vein thrombosis' by not providing £1 a day drugs

Figures show two-thirds of NHS hospitals are breaching their legal duty by failing to protect the majority of patients at high risk of blood clots on their wards. (Source: the Mail online | Health)

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 24 Nov 2010 6:01:39 am

Deep Vein Thrombosis (DVT) - news item 126 of 148

Subcutaneous Unfractionated Heparin for Treatment of Venous Thromboembolism in End-Stage Renal Disease (December).

CONCLUSIONS: Safe and convenient treatment options for VTE in patients with ESRD are limited. Fixed-dose, unmonitored subcutaneous UFH as a bridge to warfarin therapy is an effective option in patients with ESRD and those with financial restrictions. The pharmacist plays a key role in identifying patients for whom subcutaneous UFH...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 22 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 127 of 148

Catheter-Directed Thrombectomy and Thrombolysis for Symptomatic Lower-Extremity Deep Vein Thrombosis: Review of Current Interventional Treatment Strategies

This article reviews the current advances in this technology and discusses the techniques of percutaneous treatment strategies of venous thrombotic conditions using various devices, including the AngioJet Power Pulse system, Trellis, and ultrasound-accelerated EkoSonic system. Finally, the authors’ institutional experiences using these interventional treatment strategies in patients with acute and...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 21 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 128 of 148

Endovascular Treatment of Phlegmasia Cerulea Dolens with Impending Venous Gangrene: Manual Aspiration Thrombectomy as the First-Line Thrombus Removal Method

Conclusions Manual aspiration thrombectomy with adjunctive use of catheter-directed thrombolysis and stent placement is an effective endovascular treatment method with high clinical success and survival rates for phlegmasia cerulean dolens. Content Type Journal ArticleDOI 10.1007/s00270-010-0042-5Authors Levent Oguzkurt, Department of Radiology, Baskent University Faculty of Medicine, Adana Teaching and Medical Research...

RSS Source:   Med Worm - Deep Vein Thrombosis Sat, 20 Nov 2010 5:55:51 am

Deep Vein Thrombosis (DVT) - news item 129 of 148

Validation of the Caprini Risk Assessment Model in Plastic and Reconstructive Surgery Patients

Conclusions: The Caprini RAM effectively risk-stratifies plastic and reconstructive surgery patients for VTE risk. Among patients with Caprini score >8, 11.3% have a postoperative VTE when chemoprophylaxis is not provided. In higher risk patients, there was no evidence that VTE risk is limited to the immediate postoperative period. (Source: Journal...

RSS Source:   Med Worm - Deep Vein Thrombosis Wed, 17 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 130 of 148

Differences in Etiological and Clinical Manifestations in Upper Extremity and Lower Limb Deep Venous Thrombosis Patients From India

We assessed the clinical manifestations in upper and lower limb deep venous thrombosis patients from India and difference in etiological factors. Fifty-three patients with primary upper extremity deep vein thrombosis (UEDVT; males 30, females 23) and 236 patients with lower limb deep vein thrombosis (LLDVT; males 157, females 79) were...

RSS Source:   Med Worm - Deep Vein Thrombosis Sat, 13 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 131 of 148

Mechanical Methods for Thrombosis Prophylaxis

Prevention of venous thromboembolism (VTE) remains the number one preventable cause of death in hospitalized patients. The pathogenesis of thrombosis involves the triad of venous stasis, dilatation of the leg veins, and changes in coagulability of the blood. These changes can be modified by the use of intermittent pneumatic compression...

RSS Source:   Med Worm - Deep Vein Thrombosis Sat, 13 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 132 of 148

Massive Pulmonary Embolism and Acute Limb Ischaemia in a Patient of Hereditary Spherocytosis and Patent Foramen Ovale

Paradoxical embolism accounts for 2% of patients who present with acute arterial embolism of extremities. We report a case of a 41 year-old male with hereditary spherocytosis who presented to the emergency department with acute limb ischaemia and pulmonary embolism. On further evaluation, he was found to have patent foramen...

RSS Source:   Med Worm - Deep Vein Thrombosis Sat, 13 Nov 2010 1:25:20 am

Deep Vein Thrombosis (DVT) - news item 133 of 148

Efficacy and safety of a pharmacist‐managed inpatient anticoagulation service for warfarin initiation and titration

Conclusion:  Inpatient anticoagulation care and outcomes were significantly improved by a pharmacist‐managed anticoagulation service. The time to therapeutic INR was achieved appropriately and efficiently without compromising patient’s safety. (Source: Journal of Clinical Pharmacy and Therapeutics)

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 11 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 134 of 148

Interobserver agreement on ultrasound diameter measurements of acute proximal and distal deep vein thrombosis

(Source: Journal of Thrombosis and Haemostasis)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 9 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 135 of 148

Anticoagulant Utilization Evaluation in a Teaching Hospital: A Prospective Study

Conclusion: Despite the existence of comprehensive guidelines for the prevention and treatment of DVT and PE, it is not performed accurately. (Source: Journal of Pharmacy Practice) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 9 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 136 of 148

Unnecessary Blood Testing In Elderly Patients Reduced By Real-Time Physician Electronic Alerts

An electronic message sent to physicians the moment they ordered a blood test for elderly patients reduced unnecessary use of the test that is often false-positive for the elderly, according to a paper published in the November edition of American Journal of Managed Care. The D-dimer test, combined with a...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 8 Nov 2010 10:00:00 am

Deep Vein Thrombosis (DVT) - news item 137 of 148

A phase I, dose-escalation study of pomalidomide (CC-4047) in combination with gemcitabine in metastatic pancreas cancer

Conclusions: The combination of pomalidomide and gemcitabine was feasible and safe in most patients receiving first-line chemotherapy for metastatic pancreatic cancer. Neutropaenia, the dose-limiting toxicity, was brief and reversible. Intermittent dosing of pomalidomide allowed substantially higher doses than were previously reported with a continuous schedule. This combination merits further evaluation...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 7 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 138 of 148

Markers of Thrombin Generation During Resurfacing and Noncemented Total Hip Arthroplasty: A Pilot Study.

CONCLUSION: Based on these data, HRA and THA should have similar risk of thromboembolism as THA based on the parameters we measured. LEVEL OF EVIDENCE: Level I, diagnostic study. See Guidelines for Authors for a complete description of levels of evidence. PMID: 21057987 [PubMed - as supplied by publisher] (Source:...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 4 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 139 of 148

Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis.

Authors: Salomon O, Steinberg DM, Zucker M, Varon D, Zivelin A, Seligsohn U Factor XI (FXI) plays a dual role in haemostasis and thrombosis. It contributes to thrombin generation and promotes inhibition of fibrinolysis. Severe FXI deficiency was shown to confer protection against arterial and venous thrombosis in animal models...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 4 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 140 of 148

Deep Vein Thrombosis Prophylaxis in Hospitalized Medical Patients: Current Recommendations, General Rates of Implementation, and Initiatives for Improvement

Venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism, is a leading cause of preventable morbidity and mortality following hospitalization. In the last decade, investigators have used randomized controlled trials to assess the efficacy and safety of various methods of VTE prevention for more than 20,000 medical patients....

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 4 Nov 2010 12:24:00 am

Deep Vein Thrombosis (DVT) - news item 141 of 148

Preface: Venous Thromboembolism

Venous thromboembolism contributes to the death of 100,000 to 200,000 patients a year, and pulmonary embolism remains the third most common acute cardiovascular disease state behind myocardial infarction and stroke. Even for those surviving their acute thromboembolic event, morbidity remains significant with postphlebitic syndromes in approximately 30% of deep vein...

RSS Source:   Med Worm - Deep Vein Thrombosis Thu, 4 Nov 2010 12:24:00 am

Deep Vein Thrombosis (DVT) - news item 142 of 148

Outcomes Using a 1470-nm Laser for Symptomatic Varicose Veins

Conclusions: EVLA, using 1470-nm laser, is a minimally invasive, safe, outpatient department (OPD) procedure that causes less postprocedural pain with linear endovenous energy density (LEED) less than 100J/cm. (Source: Journal of Vascular and Interventional Radiology : JVIR)

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 2 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 143 of 148

Topical Application of Tranexamic Acid Reduces Postoperative Blood Loss in Total Knee Arthroplasty: A Randomized, Controlled Trial

Conclusions: At the conclusion of a total knee arthroplasty with cement, topical application of tranexamic acid directly into the surgical wound reduced postoperative bleeding by 20% to 25%, or 300 to 400 mL, resulting in 16% to 17% higher postoperative hemoglobin levels compared with placebo, with no clinically important increase...

RSS Source:   Med Worm - Deep Vein Thrombosis Tue, 2 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 144 of 148

Total Knee Replacement and Chemical Thromboprophylaxis: Current Evidence.

Authors: Nikolaou VS, Bergeron SG, Bergeron SG, Antoniou J Thromboembolic disease remains one of the most devastating and potentially lethal complications after elective total knee replacement (TKR) surgery. Studies have shown that 40-85% of patients undergoing TKR will develop venographically confirmed deep vein thrombosis (DVT) if they are not given...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 1 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 145 of 148

Early Postoperative Bleeding in Polytrauma Patients Treated with Fondaparinux: Literature Review and Institutional Experience.

Authors: Tsiridis E, Gamie Z, George MJ, Hamilton-Baille D, West RM, Giannoudis PV Surgery for pelvic or acetabular fractures carries a high risk of deep-vein thrombosis (DVT). Reports indicate that fondaparinux is a more effective thromboprophylactic agent than low molecular weight heparin (LMWH) after major orthopaedic surgery. The safety and...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 1 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 146 of 148

Incidence and Prevention of Thromboembolic Events in One Stage Bilateral Total Hip Arthroplasty: A Systematic Review.

Authors: Babis GC, Sakellariou V, Johnson EO, Soucacos PN We conducted a thorough search of all the English language literature and carried out a meta-analysis in an attempt to reveal potential differences on the incidence of deep vein thrombosis (DVT) and pulmonary embolism (PE) between one stage bilateral and unilateral...

RSS Source:   Med Worm - Deep Vein Thrombosis Mon, 1 Nov 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 147 of 148

Invited commentary

Much high-quality evidence exists for the effective therapy for acute deep vein thrombosis (DVT); namely, rapid and therapeutic low-molecular-weight heparin (LMWH) anticoagulation, followed by transition to a vitamin K antagonist, early application of compression therapy, and ambulation. Moreover, markers for ceasing or continuing oral anticoagulation are now coming to light,...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 31 Oct 2010 11:00:00 pm

Deep Vein Thrombosis (DVT) - news item 148 of 148

Does the clinical presentation and extent of venous thrombosis predict likelihood and type of recurrence? A patient‐level meta‐analysis

Conclusion: Whilst DVT and PE are manifestations of the same disease, the phenotypic expression is predetermined. Patients presenting with PE are three times more likely to suffer recurrence as PE than patients presenting with DVT. Patients presenting with calf DVT are at low risk of recurrence and at low risk of...

RSS Source:   Med Worm - Deep Vein Thrombosis Sun, 31 Oct 2010 11:00:00 pm