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Mon, 07 Mar 2011 at 20:35:59


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Glaucoma - news item 1 of 146
Topiramate: Angle closure glaucoma and uveitis: case report
(Source: Reactions)
RSS Source:   Med Worm - Glaucoma Sun, 6 Mar 2011 4:02:10 pm
Glaucoma - news item 2 of 146
Acetazolamide: Glaucoma and choroidal effusion in an elderly patient: case report
(Source: Reactions)
RSS Source:   Med Worm - Glaucoma Sun, 6 Mar 2011 4:02:10 pm
Glaucoma - news item 3 of 146
Phyllidia Law: Your eyes need looking after
Actress Phyllida Law has learned to live with glaucoma and wants to raise awareness of the disease. (Source: Telegraph Health)
RSS Source:   Med Worm - Glaucoma Fri, 4 Mar 2011 10:20:03 am
Glaucoma - news item 4 of 146
Visual outcome in ocular sarcoidosis: retrospective evaluation of risk factors.
Conclusions. In this study, we attempted to find risk factors related to poor visual outcome in patients with ocular sarcoidosis. The results suggest that only the presence of cystoid macular edema was significantly associated with worst visual outcome. PMID: 21374555 [PubMed - as supplied by publisher] (Source: European Journal of...
RSS Source:   Med Worm - Glaucoma Wed, 2 Mar 2011 11:00:00 pm
Glaucoma - news item 5 of 146
Alzheimer's Disease and Glaucoma: Imaging the Biomarkers of Neurodegenerative Disease
Imaging through the visual system in Alzheimer's disease, with the technology currently in widespread use for the diagnosis and management of eye disease such as glaucoma and macular degeneration, is proving to be promising. In vivo cross-section imaging during an annual comprehensive eye exam has been available for a decade...
RSS Source:   Med Worm - Glaucoma Wed, 2 Mar 2011 2:47:49 pm
Glaucoma - news item 6 of 146
Heat Shock Proteins in the Human Eye
Heat shock proteins (Hsps) are believed to primarily protect and maintain cell viability under stressful conditions such as those occurring during thermal and oxidative challenges chiefly by refolding and stabilizing proteins. Hsps are found throughout the various tissues of the eye where they are thought to confer protection from disease...
RSS Source:   Med Worm - Glaucoma Wed, 2 Mar 2011 1:55:17 pm
Glaucoma - news item 7 of 146
Eprosartan mesylate, an angiotensin II receptor antagonist
The title compound, eprosartan mesylate {systematic name: 2-butyl-1-(4-carboxybenzyl)-5-[(E)-2-carboxy-3-(thiophen-2-yl)prop-1-enyl]-1H-imidazol-3-ium methanesulfonate}, C23H25N2O4S+·CH3O3Sâˆ', one of the angiotensin II-receptor antagonists, is effective in regulating hypertension, induced or exacerbated by angiotensin II, and in the treatment of congestive heart failure, renal failure and glaucoma. In the eprosartan residue, which appears in this crystal in the...
RSS Source:   Med Worm - Glaucoma Tue, 1 Mar 2011 11:00:00 pm
Glaucoma - news item 8 of 146
Sturge†Weber syndrome: decrease in intraocular pressure after transpupillary thermotherapy for diffuse choroidal haemangioma
Conclusions:  Our study highlights the close link that exists between LOJG and DCH in SWS. A single treatment modality such as TTT may both reduce IOP in LOJG and help to prevent exudative retinal detachment in DCH. We believe that TTT is a good therapeutic option for SWS patients who...
RSS Source:   Med Worm - Glaucoma Mon, 28 Feb 2011 11:00:00 pm
Glaucoma - news item 9 of 146
Primary open-angle glaucoma.
Authors: Yumori JW, Cadogan MP Glaucoma is an optic neuropathy that is usually associated with an elevated intraocular pressure. Primary open-angle glaucoma (POAG) is the most common type of glaucoma and is progressive and bilateral but typically asymmetric in patients. Studies have shown that reducing intraocular pressure reduces the risk...
RSS Source:   Med Worm - Glaucoma Mon, 28 Feb 2011 11:00:00 pm
Glaucoma - news item 10 of 146
Epidemiology of canine glaucoma presented to University of Zurich from 1995 to 2009. Part 2: secondary glaucoma (217 cases)
Conclusion  The report presents the epidemiology of secondary glaucomas presented to UZH from 1995 to 2009. Fourteen risk factors were recorded for secondary glaucoma. This is the first paper documenting OM in the Swiss Cairn Terrier dog population. (Source: Veterinary Ophthalmology)
RSS Source:   Med Worm - Glaucoma Mon, 28 Feb 2011 11:00:00 pm
Glaucoma - news item 11 of 146
Epidemiology of canine glaucoma presented to University of Zurich from 1995 to 2009. Part 1: Congenital and primary glaucoma (4 and 123 cases)
Conclusion  The report presents the epidemiology of canine congenital and primary glaucomas presented to the UZH from 1995 to 2009. A previous suspicion of predisposition for primary glaucoma in the Newfoundland dog (n = 6) and the Magyar Vizsla breed (n = 8) was confirmed. (Source: Veterinary Ophthalmology) MedWorm Message: Watch the new MedWorm...
RSS Source:   Med Worm - Glaucoma Mon, 28 Feb 2011 11:00:00 pm
Glaucoma - news item 12 of 146
Postoperative complications and visual outcomes of phacoemulsification in 103 dogs (179 eyes): 2006†2008
Conclusion  The prognosis for vision after phacoemulsification with injectable IOL placement is good. Boston terriers were at much higher risk for certain complications. (Source: Veterinary Ophthalmology)
RSS Source:   Med Worm - Glaucoma Mon, 28 Feb 2011 11:00:00 pm
Glaucoma - news item 13 of 146
Clinician-Patient Communication in a Glaucoma Clinic in India
We compiled data from nonparticipant observations of clinician—patient communication in clinical interactions in a tertiary care eye hospital in India. Applying elements of the French philosopher Michel Foucault’s concept of power and knowledge, we deconstructed the structuring and moderating influences on the expert/nonexpert dyad. We found that clinicians enforce their "...
RSS Source:   Med Worm - Glaucoma Mon, 28 Feb 2011 11:00:00 pm
Glaucoma - news item 14 of 146
Bilateral acute angle closure glaucoma as the presenting feature of a systemic leukocytoclastic vasculitis
(Source: Clinical and Experimental Ophthalmology)
RSS Source:   Med Worm - Glaucoma Mon, 28 Feb 2011 11:00:00 pm
Glaucoma - news item 15 of 146
[One-year results after combined cataract surgery and excimer laser trabeculotomy for elevated intraocular pressure.]
CONCLUSION: The ELT is easy to perform at the end of cataract surgery. Duration of surgery is only prolonged by 2 to 3 minutes. We found an average IOP reduction of 8.79 mmHg (-34.70%) and an average reduction of 0.79 AGD. It is known that the effect of IOP reduction...
RSS Source:   Med Worm - Glaucoma Sat, 26 Feb 2011 11:00:00 pm
Glaucoma - news item 16 of 146
THC for Huntington's Disease? CB1 receptors important for more than drug use
Everyone has heard of some of the medical benefits of marijuana - Glaucoma, anti-nausea, making T.V. funnier - but this early evidence that "weed" might help slow the development of one of our most devestating neurological disorders caught my eye.read more (Source: Psychology Today Addiction Center) MedWorm Message: Watch the...
RSS Source:   Med Worm - Glaucoma Sat, 26 Feb 2011 1:19:10 am
Glaucoma - news item 17 of 146
Fungal keratitis after nonpenetrating glaucoma surgery
Tamcelik N, Ozdamar A, Kizilkaya M, Devranoglu K, Ustundag C, Demirkesen C (Source: The Aspergillus Website - articles)
RSS Source:   Med Worm - Glaucoma Fri, 25 Feb 2011 12:04:32 pm
Glaucoma - news item 18 of 146
The relationship between macular cell layer thickness and visual function in different stages of glaucoma
Authors: T S Vajaranant, R J Anderson, R Zelkha, C Zhang, J T Wilensky, D P Edward & M Shahidi (Source: Eye)
RSS Source:   Med Worm - Glaucoma Fri, 25 Feb 2011 7:00:00 am
Glaucoma - news item 19 of 146
A dual acting compound with latanoprost amide and nitric oxide releasing properties, Shows ocular hypotensive effects in rabbits and dogs.
Authors: Impagnatiello F, Borghi V, Gale DC, Batugo M, Guzzetta M, Brambilla S, Carreiro ST, Chong WK, Prasanna G, Chiroli V, Ongini E, Krauss AH The IOP lowering effects of NCX 139, a new chemical entity comprising latanoprost amide and a NO-donating moiety, were compared to those of the respective...
RSS Source:   Med Worm - Glaucoma Thu, 24 Feb 2011 11:00:00 pm
Glaucoma - news item 20 of 146
Researchers create computer that fits on a pen tip
Researchers at the University of Michigan have created a micro-computer that will first be used in medical applications, like measuring eye pressure for glaucoma patients. (Source: Computerworld Health Care News)
RSS Source:   Med Worm - Glaucoma Thu, 24 Feb 2011 4:41:14 pm
Glaucoma - news item 21 of 146
Real-time measurements of nicotinamide adenine dinucleotide in live human trabecular meshwork cells: Effects of acute oxidative stress.
In this report, we have used two-photon excitation autofluorescence (2PAF) to monitor changes to TM cell nicotinamide adenine dinucleotide (NADPH). 2PAF allows non-destructive, real-time analysis of concentration of intracellular NADPH. Coupled to reduced glutathione, NADPH, is a major component in the anti-oxidant defense of TM cells. Cultured human TM cells...
RSS Source:   Med Worm - Glaucoma Wed, 23 Feb 2011 11:00:00 pm
Glaucoma - news item 22 of 146
[Complications after cosmetic iris implantation.]
We report the case of a 37-year-old patient with ocular complications associated with the implantation of cosmetic iris implants. Implantation of silicone iris implants for the purpose of changing iris colour has been performed since 2004. Diaphragms are implanted in the anterior chamber. Up to now only little information exists...
RSS Source:   Med Worm - Glaucoma Wed, 23 Feb 2011 11:00:00 pm
Glaucoma - news item 23 of 146
Reduction of intra‐ocular pressure by ocular compression before combined peri‐ and retrobulbar block
SummaryThe intra‐ocular pressure immediately before glaucoma surgery can be raised. We wished to investigate if ocular compression for 20 min before a combined peri‐ and retrobulbar injection would result in a lower pressure after the block. Sixty consecutive patients scheduled for filtration surgery were randomly assigned to receive ocular compression using...
RSS Source:   Med Worm - Glaucoma Wed, 23 Feb 2011 11:00:00 pm
Glaucoma - news item 24 of 146
The Phoenix microcomputer chip
Scientists at the University of Michigan have created a micro-computer that is a giant leap toward millimeter-scale computing and that will first be used in medical applications, like measuring eye pressure for glaucoma patients. (Source: Computerworld Health Care News)
RSS Source:   Med Worm - Glaucoma Wed, 23 Feb 2011 8:10:00 pm
Glaucoma - news item 25 of 146
Podcast: Alan Carlson, MD, on Duke Eye Center
In this podcast, Alan Carlson, MD, professor of ophthalmology at the Duke Eye Center and chief of corneal and refractive eye surgery, discusses the latest advances in eye care at Duke. Listen to the Podcast (Download audio) Podcast Transcript Announcer: Throughout the season you often listen in on our pregame...
RSS Source:   Med Worm - Glaucoma Wed, 23 Feb 2011 7:08:59 pm
Glaucoma - news item 26 of 146
Toward computers that fit on a pen tip: New technologies usher in the millimeter-scale computing era
A prototype implantable eye pressure monitor for glaucoma patients is believed to contain the first complete millimeter-scale computing system. (Source: ScienceDaily Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Glaucoma Wed, 23 Feb 2011 3:00:00 pm
Glaucoma - news item 27 of 146
New Technologies Usher In The Millimeter-Scale Computing Era
A prototype implantable eye pressure monitor for glaucoma patients is believed to contain the first complete millimeter-scale computing system. And a compact radio that needs no tuning to find the right frequency could be a key enabler to organizing millimeter-scale systems into wireless sensor networks. These networks could one day...
RSS Source:   Med Worm - Glaucoma Wed, 23 Feb 2011 8:00:00 am
Glaucoma - news item 28 of 146
Dilated episcleral veins with secondary open angle glaucoma
We report a case of dilated episcleral vein with secondary open angle glaucoma. A 65-year-old female presented with redness of both the eyes without any prior systemic history. Her ocular examination revealed dilated episcleral veins and a high intraocular pressure (IOP) of 38 mm Hg in the right eye. Systemic...
RSS Source:   Med Worm - Glaucoma Tue, 22 Feb 2011 11:00:00 pm
Glaucoma - news item 29 of 146
A comparative study between intravitreal triamcinolone and bevacizumab for macular edema due to central retinal vein occlusion with poor vision
Conclusion: In patients with CRVO and poor vision, intravitreal bevacizumab and intravitreal triamcinolone were associated with a reduction in macular edema; however, neither treatment achieved significant visual acuity improvement by the 12-month follow-up. (Source: Indian Journal of Ophthalmology)
RSS Source:   Med Worm - Glaucoma Tue, 22 Feb 2011 11:00:00 pm
Glaucoma - news item 30 of 146
Myocilin, a glaucoma‐associated protein, promotes cell migration through activation of integrin‐focal adhesion kinase‐serine/threonine kinase signaling pathway
AbstractThe MYOCILIN gene encodes a secreted glycoprotein which is highly expressed in eye drainage structures. Mutations in this gene may lead to juvenile open‐angle glaucoma and adult onset primary open‐angle glaucoma, one of the leading causes of irreversible blindness in the world. Functions of wild‐type myocilin are still unclear. We...
RSS Source:   Med Worm - Glaucoma Mon, 21 Feb 2011 11:00:00 pm
Glaucoma - news item 31 of 146
MfERG responses to long-duration white stimuli in glaucoma patients
Abstract The intent of our study was to evaluate whether the response to a long-duration white stimulus in the multifocal electroretinogram (mfERG) is sufficiently sensitive to detect early retinal dysfunction in glaucoma. On†off mfERGs were recorded from 15 NTG and 15 HTG patients and compared with 14 control subjects....
RSS Source:   Med Worm - Glaucoma Mon, 21 Feb 2011 3:57:46 pm
Glaucoma - news item 32 of 146
Happy birthday, President Lincoln. Now, about that Marfan syndrome …
We know he was tall, honest and a great speaker, but did America’s most beloved president also have a serious genetic disorder? According to many in the scientific community, the answer is yes.  A standing theory is that Abe Lincoln may have had Marfan syndrome, a serious genetic disorder that...
RSS Source:   Med Worm - Glaucoma Mon, 21 Feb 2011 2:08:30 pm
Glaucoma - news item 33 of 146
Novel Insights Into Glaucoma Pathology Following Identification Of Glaucoma Gene
Glaucoma - a leading cause of vision loss and blindness worldwide - runs in families. A team of investigators from Vanderbilt University and the University of Florida has identified a new candidate gene for the most common form of the eye disorder, primary open angle glaucoma (POAG). The findings, reported...
RSS Source:   Med Worm - Glaucoma Sat, 19 Feb 2011 7:00:00 am
Glaucoma - news item 34 of 146
Identification of glaucoma gene brightens view for future therapies
Glaucoma -- a leading cause of vision loss and blindness worldwide -- runs in families. A team of investigators has identified a new candidate gene for the most common form of the eye disorder, primary open angle glaucoma. The findings offer novel insights into glaucoma pathology and could lead to...
RSS Source:   Med Worm - Glaucoma Fri, 18 Feb 2011 9:00:00 pm
Glaucoma - news item 35 of 146
Obesity Linked to Lower Glaucoma Risk in Women
Each additional unit of BMI drops open-angle glaucoma risk by 7% in women. Medscape Medical News (Source: Medscape Today Headlines)
RSS Source:   Med Worm - Glaucoma Fri, 18 Feb 2011 7:52:51 pm
Glaucoma - news item 36 of 146
Female reproductive factors and primary open-angle glaucoma in the Nurses’ Health Study
Female reproductive factors and primary open-angle glaucoma in the Nurses’ Health Study Eye advance online publication, February 18, 2011. doi:10.1038/eye.2011.34 Authors: L R Pasquale & J H Kang (Source: Eye)
RSS Source:   Med Worm - Glaucoma Fri, 18 Feb 2011 7:00:00 am
Glaucoma - news item 37 of 146
Comparison of scheimpflug imaging and spectral domain anterior segment optical coherence tomography for detection of narrow anterior chamber angles
Authors: D S Grewal, G S Brar, R Jain & S P S Grewal (Source: Eye) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Glaucoma Fri, 18 Feb 2011 7:00:00 am
Glaucoma - news item 38 of 146
Intravitreal bevacizumab for iris metastasis of small-cell lung carcinoma with neovascular glaucoma
Content Type Journal ArticlePages 80-81DOI 10.1007/s10384-010-0892-zAuthors Chikae Nakashima, Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, JapanHiroshi Keino, Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, JapanTakayo Watanabe, Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, JapanWakako Taki, Department of Ophthalmology, Kyorin University School of Medicine, Tokyo,...
RSS Source:   Med Worm - Glaucoma Fri, 18 Feb 2011 5:55:09 am
Glaucoma - news item 39 of 146
Retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: A comparison using optical coherence tomography
Conclusion Participants with mild POAG had deeper and more localized RNFL defects than did participants with PACG. The pattern was similar in participants with moderate or advanced disease. Content Type Journal ArticlePages 28-34DOI 10.1007/s10384-010-0898-6Authors Anita Manassakorn, Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandSoontaree Aupapong, Department...
RSS Source:   Med Worm - Glaucoma Fri, 18 Feb 2011 5:54:59 am
Glaucoma - news item 40 of 146
[Bilateral acute angle-closure glaucoma due to an infection with Hantavirus.]
Authors: Zimmermann A, Lorenz B, Schmidt W A poor general condition of patients with hemorrhagic fever and elevated creatinine should raise suspicion of a systemic infection with Hantavirus. This can often also cause ocular changes. Above all, changes of intraocular pressure, in our case bilateral acute angle-closure glaucoma, due to...
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 11:00:00 pm
Glaucoma - news item 41 of 146
Glaucoma‐like optic neuropathy in patients with intracranial tumours
Conclusions:  Large perisellar tumours were associated with a glaucoma‐like appearance of the optic nerve head in eyes. It may diagnostically and pathogenetically be of importance. (Source: Acta Ophthalmologica)
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 11:00:00 pm
Glaucoma - news item 42 of 146
Thickness of the lamina cribrosa and peripapillary sclera in Rhesus monkeys with nonglaucomatous or glaucomatous optic neuropathy
Conclusions:  In monkey eyes with a temporary CRAO as a model for nonglaucomatous optic nerve damage, the lamina cribrosa is significantly thicker than in monkey eyes with experimental glaucomatous optic nerve damage. It may suggest that the loss of optic nerve fibres might not be the reason for the thinning...
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 11:00:00 pm
Glaucoma - news item 43 of 146
Normal tension glaucoma and Alzheimer disease: comorbidity?
Conclusion:  Normal tension glaucoma was not associated with an increased risk of developing dementia/AD. (Source: Acta Ophthalmologica)
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 11:00:00 pm
Glaucoma - news item 44 of 146
Decreased Glaucoma Risk Seen in Obese Women
Obesity in women is linked to increased intraocular pressure and a reduced risk of developing open-angle glaucoma, according to a study published online Feb. 14 in the Archives of Ophthalmology. (Source: Modern Medicine)
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 11:00:00 pm
Glaucoma - news item 45 of 146
Optic disc area and correlation with central corneal thickness, corneal hysteresis and ocular pulse amplitude in glaucoma patients and controls: comment
(Source: Clinical and Experimental Ophthalmology)
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 11:00:00 pm
Glaucoma - news item 46 of 146
Economic impact of primary open angle glaucoma in Australia
Conclusion: POAG poses a significant economic burden, which will increase substantially by 2025. This dynamic model provides a valuable tool for ongoing policy formulation and determining the economic impact of interventions to better prevent visual impairment and blindness from glaucoma. (Source: Clinical and Experimental Ophthalmology)
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 11:00:00 pm
Glaucoma - news item 47 of 146
Comparison of standard trabeculectomy versus microtrabeculectomy as a surgical treatment for glaucoma: a randomised clinical trial
Conclusion: Both trabeculectomy techniques achieved good IOP reduction and had similar complication rates. Scleral flap size had no significant effect on medium‐term IOP control and complication profile. (Source: Clinical and Experimental Ophthalmology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant,...
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 11:00:00 pm
Glaucoma - news item 48 of 146
Optic disc area and correlation with central corneal thickness, corneal hysteresis and ocular pulse amplitude in glaucoma patients and controls: response
(Source: Clinical and Experimental Ophthalmology)
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 11:00:00 pm
Glaucoma - news item 49 of 146
Ephedrine/general anaesthetics: Angle closure glaucoma in an elderly patient: case report
(Source: Reactions)
RSS Source:   Med Worm - Glaucoma Thu, 17 Feb 2011 3:50:41 pm
Glaucoma - news item 50 of 146
Mutations in Zebrafish lrp2 Result in Adult-Onset Ocular Pathogenesis That Models Myopia and Other Risk Factors for Glaucoma
In this study, we present analysis of a zebrafish mutant, bugeye, which shows complex inheritance of multiple ocular phenotypes that are known risk factors for glaucoma, including high myopia, elevated intraocular pressure, and up-regulation of stress-response genes in retinal ganglion cells. Molecular genetic analysis revealed that mutations in low density...
RSS Source:   Med Worm - Glaucoma Wed, 16 Feb 2011 11:00:00 pm
Glaucoma - news item 51 of 146
Mapping of the Disease Locus and Identification of ADAMTS10 As a Candidate Gene in a Canine Model of Primary Open Angle Glaucoma
Author Summary Primary open angle glaucoma (POAG) is a leading cause of vision loss and blindness affecting tens of millions of people. Ocular hypertension is a strong risk factor for the disease and the only effective target of treatment. Ocular hypertension results from increased resistance to outflow of aqueous humor...
RSS Source:   Med Worm - Glaucoma Wed, 16 Feb 2011 11:00:00 pm
Glaucoma - news item 52 of 146
Applications of the multifocal electroretinogram in the detection of glaucoma
Glaucoma is one of the most important eye diseases resulting in blindness worldwide. It affects the inner retina and is without signs and symptoms in the early stages, making early detection of glaucoma important for eye care professionals. Electroretinography (ERG) is an objective technique used to measure retinal electrical responses,...
RSS Source:   Med Worm - Glaucoma Tue, 15 Feb 2011 11:00:00 pm
Glaucoma - news item 53 of 146
Pupillary block glaucoma secondary to vitreous prolapse after Nd:YAG capsulotomy
(Source: Clinical and Experimental Optometry)
RSS Source:   Med Worm - Glaucoma Tue, 15 Feb 2011 11:00:00 pm
Glaucoma - news item 54 of 146
GRF applauds donors
"The Glaucoma Research Foundation (GRF) ?applauded those who give? at its annual benefit and celebration Jan. 26. The theme of this year?s dinner, auction, and presentations was ?Applauding Those Who Give,? and the benefit focused on recent results from GRF-funded research and the donors who made it possible. " (Source:...
RSS Source:   Med Worm - Glaucoma Tue, 15 Feb 2011 8:16:22 pm
Glaucoma - news item 55 of 146
Obese women may be less likely to develop glaucoma
Obesity may be associated with higher eye pressure and a decreased risk of open-angle glaucoma in women but not men, according to a new article. (Source: ScienceDaily Headlines)
RSS Source:   Med Worm - Glaucoma Tue, 15 Feb 2011 6:00:00 pm
Glaucoma - news item 56 of 146
Obesity Seems to Cut Women's Risk of Open-Angle Glaucoma
Title: Obesity Seems to Cut Women's Risk of Open-Angle GlaucomaCategory: Health NewsCreated: 2/14/2011 8:05:00 PMLast Editorial Review: 2/15/2011 (Source: MedicineNet Menopause General) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Glaucoma Tue, 15 Feb 2011 6:00:00 am
Glaucoma - news item 57 of 146
Genetic architecture of open angle glaucoma and related determinants
Conclusions We found evidence for a polygenic model underlying one of the major traits of OAG, VCDR, and OAG itself. The IOP did not show any evidence for such a model. (Source: Journal of Medical Genetics)
RSS Source:   Med Worm - Glaucoma Mon, 14 Feb 2011 11:00:00 pm
Glaucoma - news item 58 of 146
Glaucoma Risk in Women Falls With Rising BMI (CME/CE)
(MedPage Today) -- Women's risk of open-angle glaucoma (OAG) decreased significantly as body mass index (BMI) increased, according to data from a large cohort study. (Source: MedPage Today Ophthalmology)
RSS Source:   Med Worm - Glaucoma Mon, 14 Feb 2011 9:43:07 pm
Glaucoma - news item 59 of 146
Obesity Seems to Cut Women’s Risk of Open-Angle Glaucoma
Researchers suspect association may be due to estrogen (Source: The Doctors Lounge - Health News)
RSS Source:   Med Worm - Glaucoma Mon, 14 Feb 2011 9:00:00 pm
Glaucoma - news item 60 of 146
Overweight women show lower glaucoma risk
NEW YORK (Reuters Health) - Overweight older women may be less likely than their thinner peers to develop the potentially blinding eye disease glaucoma, a study published Monday suggests. (Source: Reuters: Health)
RSS Source:   Med Worm - Glaucoma Mon, 14 Feb 2011 8:18:14 pm
Glaucoma - news item 61 of 146
Dendritic changes in visual pathways in glaucoma and other neurodegenerative conditions.
Authors: Liu M, Duggan J, Salt TE, Cordeiro MF Visual information is sent from the retina to central visual targets through the optic nerve formed of retinal ganglion cells' (RGCs) axons. In rodents, the superior colliculus (SC) is the major site of termination of retinal axons, whilst in primates and...
RSS Source:   Med Worm - Glaucoma Sun, 13 Feb 2011 11:00:00 pm
Glaucoma - news item 62 of 146
Effect of Glucose on the Stress-Strain Behavior of ex-vivo Rabbit Cornea.
Authors: Ni S, Yu J, Bao F, Li J, Elsheikh A, Wang Q The biomechanical changes in rabbit cornea preserved in storage media with different glucose concentrations are experimentally assessed. Two groups of eight fresh rabbit corneas were preserved for 10 days in storage medium Optisol-GS with glucose concentrations of...
RSS Source:   Med Worm - Glaucoma Sun, 13 Feb 2011 11:00:00 pm
Glaucoma - news item 63 of 146
An Unusual Manifestation of Herpes Simplex Virus-Associated Acute Iris Depigmentation and Pigmentary Glaucoma [Research Letters]
(Source: Archives of Opthalmology)
RSS Source:   Med Worm - Glaucoma Sun, 13 Feb 2011 11:00:00 pm
Glaucoma - news item 64 of 146
Glaucoma Medication Adherence: Room for Improvement in Both Performance and Measurement [Editorial]
(Source: Archives of Opthalmology)
RSS Source:   Med Worm - Glaucoma Sun, 13 Feb 2011 11:00:00 pm
Glaucoma - news item 65 of 146
An Investigation Into LOXL1 Variants in Black South African Individuals With Exfoliation Syndrome [Ophthalmic Molecular Genetics]
Conclusion The LOXL1 SNPs R141L and G153D are significantly associated with XFS in this black South African population. The AA genotype of G153D confers XFS risk in this population, as opposed to the GG genotype described in all other populations, suggesting that unidentified genetic or environmental factors independent of these...
RSS Source:   Med Worm - Glaucoma Sun, 13 Feb 2011 11:00:00 pm
Glaucoma - news item 66 of 146
Trabeculectomy With Mitomycin for Open-Angle Glaucoma in Phakic vs Pseudophakic Eyes After Phacoemulsification [Clinical Sciences]
Conclusion Previous phacoemulsification is a prognostic factor for surgical failure of trabeculectomy with mitomycin for open-angle glaucoma. (Source: Archives of Opthalmology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Glaucoma Sun, 13 Feb 2011 11:00:00 pm
Glaucoma - news item 67 of 146
Intravitreal Bevacizumab in Refractory Neovascular Glaucoma: A Prospective, Observational Case Series [Clinical Sciences]
Conclusions Intravitreal bevacizumab is a useful adjunct in the management of refractory neovascular glaucoma, producing rapid relief of pain. However, we found no evidence to suggest that intravitreal bevacizumab lowers intraocular pressure in eyes with angle closure; conventional medical, laser, and surgical treatment are still needed in these eyes. (Source:...
RSS Source:   Med Worm - Glaucoma Sun, 13 Feb 2011 11:00:00 pm
Glaucoma - news item 68 of 146
Lifestyle and Risk of Developing Open-Angle Glaucoma: The Rotterdam Study [Epidemiology]
Conclusions Obesity appears to be associated with a higher intraocular pressure and a lower risk of developing OAG. These associations were only present in women. Other lifestyle-related factors, such as socioeconomic status, smoking, and alcohol consumption, were not associated with OAG. (Source: Archives of Opthalmology)
RSS Source:   Med Worm - Glaucoma Sun, 13 Feb 2011 11:00:00 pm
Glaucoma - news item 69 of 146
Postoperative Infection in Penetrating Versus Non-penetrating Glaucoma Surgery
What types of infections can present after glaucoma surgery? The British Journal of Ophthalmology (Source: Medscape Ophthalmology Headlines)
RSS Source:   Med Worm - Glaucoma Fri, 11 Feb 2011 7:26:14 pm
Glaucoma - news item 70 of 146
Short-Term Results of Canaloplasty Surgery for Primary Open-Angle Glaucoma in Japanese Patients
Case Rep Ophthalmol 2011;2:65†68 (DOI:10.1159/000324808) (Source: Karger Publishers)
RSS Source:   Med Worm - Glaucoma Fri, 11 Feb 2011 2:24:39 pm
Glaucoma - news item 71 of 146
Agreement in detecting glaucomatous visual field progression by using guided progression analysis ?and Humphrey overview printout.
Conclusions. Agreement among expert clinicians about visual field progression status was moderate when GPA printouts were used. Clinicians' agreement about patients' visual field progression status was better when HFA overview printouts were used than with GPA printouts. PMID: 21319135 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)...
RSS Source:   Med Worm - Glaucoma Thu, 10 Feb 2011 11:00:00 pm
Glaucoma - news item 72 of 146
Favourable outcome after cataract surgery with IOL implantation in uveitis associated with juvenile idiopathic arthritis
Conclusions:  Phacoemulsification and in‐the‐bag IOL implantation may improve visual outcome in JIA‐associated uveitis with minimally invasive surgical technique and intravitreal TA injection. Well‐controlled uveitis with appropriate use of topical steroids and systemic immunosuppression or biologicals appears as a perioperative requirement. (Source: Acta Ophthalmologica)
RSS Source:   Med Worm - Glaucoma Thu, 10 Feb 2011 11:00:00 pm
Glaucoma - news item 73 of 146
Evaluation of a combined index of optic nerve structure and function for glaucoma diagnosis
Conclusions: The SFI reflects the traditional clinical diagnosis of glaucoma by combining optic nerve structure and function. In doing so, it identifies a different subset of patients than either visual field testing or optic nerve head imaging alone. Analysis of prospective data will allow us to determine whether the combined...
RSS Source:   Med Worm - Glaucoma Thu, 10 Feb 2011 11:00:00 pm
Glaucoma - news item 74 of 146
The optic nerve head is the site of axonal transport disruption, axonal cytoskeleton damage and putative axonal regeneration failure in a rat model of glaucoma
Abstract The neurodegenerative disease glaucoma is characterised by the progressive death of retinal ganglion cells (RGCs) and structural damage to the optic nerve (ON). New insights have been gained into the pathogenesis of glaucoma through the use of rodent models; however, a coherent picture of the early pathology remains elusive....
RSS Source:   Med Worm - Glaucoma Thu, 10 Feb 2011 6:55:56 pm
Glaucoma - news item 75 of 146
Decision making in chronic glaucoma †optometrists vs ophthalmologists in a shared care service
Conclusion:  An audit model of decision‐making in shared care is demonstrated that in this case supported the apprenticeship model of training utilised in the clinic. (Source: Ophthalmic and Physiological Optics)
RSS Source:   Med Worm - Glaucoma Thu, 10 Feb 2011 6:37:45 pm
Glaucoma - news item 76 of 146
AAO encourages patient visits during Save Your Vision Month
February is ?Save Your Vision Month,? and the American Academy of Ophthalmology (AAO) is encouraging Americans over the age of 40 to make an appointment for an eye examination. According to AAO, by 2020 43 million Americans will be at risk for significant vision loss or blindness from age-related eye...
RSS Source:   Med Worm - Glaucoma Tue, 8 Feb 2011 5:00:35 pm
Glaucoma - news item 77 of 146
Outcome of repeat trabeculectomies
Conclusions: Repeating trabeculectomy augmented with MMC is an effective method of controlling IOP and preventing further visual deterioration in the majority of patients treated. However, visual loss was seen in a significant proportion of patients. (Source: Clinical and Experimental Ophthalmology)
RSS Source:   Med Worm - Glaucoma Sun, 6 Feb 2011 11:00:00 pm
Glaucoma - news item 78 of 146
Extent of asymmetry and unilaterality among juvenile onset primary open angle glaucoma patients
Conclusions: One fourth of juvenile onset primary open angle glaucoma patients present as a unilateral optic neuropathy with 60% of these having normal IOP in the fellow eyes. Primary JOAG may present with considerable asymmetry with a small proportion presenting as a unilateral disease. (Source: Clinical and Experimental Ophthalmology) MedWorm...
RSS Source:   Med Worm - Glaucoma Sun, 6 Feb 2011 11:00:00 pm
Glaucoma - news item 79 of 146
Vogt‐Koyanagi‐Harada disease presenting as acute angle closure glaucoma at onset
Conclusion: VKH disease presenting with a bilateral increased IOP is mostly occurs in older females. The strikingly decreased visual acuity associated with mild to moderate increased IOP is a clue to the diagnosis. The increased IOP responded well to corticosteroids but not to anti‐glaucoma treatment. (Source: Clinical and Experimental Ophthalmology)
RSS Source:   Med Worm - Glaucoma Sun, 6 Feb 2011 11:00:00 pm
Glaucoma - news item 80 of 146
Atropa belladonna/pseudoephedrine/chlorphenamine: Acute angle closure glaucoma: case report
(Source: Reactions)
RSS Source:   Med Worm - Glaucoma Sun, 6 Feb 2011 3:33:07 pm
Glaucoma - news item 81 of 146
Compartment syndrome in the optic nerve: a new hypothesis in the pathogenesis of glaucoma
(Source: Acta Ophthalmologica)
RSS Source:   Med Worm - Glaucoma Fri, 4 Feb 2011 11:00:00 pm
Glaucoma - news item 82 of 146
Generation and characterization of the first inhibitory antibody targeting tumour-associated carbonic anhydrase XII
In conclusion, we generated the first specific and efficient biological inhibitor of tumour-associated CA XII. This antibody may serve as a valuable tool for in vivo diagnosis and adjuvant treatment of different types of cancer. Content Type Journal ArticlePages 1-10DOI 10.1007/s00262-011-0980-zAuthors Christina Battke, Department of Gene Vectors, Helmholtz-Center, Marchioninistr. 25,...
RSS Source:   Med Worm - Glaucoma Fri, 4 Feb 2011 4:33:57 pm
Glaucoma - news item 83 of 146
Do reducing regimens of fluorometholone for paediatric ocular surface disease cause glaucoma?
Conclusions In this cohort, reducing regimens of FML proved to be a safe anti-inflammatory treatment in terms of avoiding steroid-induced glaucoma. PMID: 21296793 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
RSS Source:   Med Worm - Glaucoma Thu, 3 Feb 2011 11:00:00 pm
Glaucoma - news item 84 of 146
Should unilateral congenital corneal opacities in Peters' anomaly be grafted?
Conclusions. Operating on a unilateral congenital corneal opacity is a challenging decision and should be taken after explaining the need for long-term follow-up to the parents. Useful vision can be achieved and maintained after strict amblyopia therapy. A multidisciplinary ophthalmologic follow-up is necessary. PMID: 21298629 [PubMed - as supplied by...
RSS Source:   Med Worm - Glaucoma Thu, 3 Feb 2011 11:00:00 pm
Glaucoma - news item 85 of 146
Diode laser cyclophotocoagulation versus cyclocryotherapy in the treatment of refractory glaucoma.
Conclusions. Both DCPC and CCT proved to be safe and effective IOP-lowering methods in patients with refractory glaucoma. Diode laser cyclophotocoagulation should be considered as the primary treatment option in refractory glaucoma using an individual treatment dosage. PMID: 21298630 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)...
RSS Source:   Med Worm - Glaucoma Thu, 3 Feb 2011 11:00:00 pm
Glaucoma - news item 86 of 146
The parameters of the porcine eyeball
Conclusion This paper describes the anatomy of the pig eyeball for easy use and interpretation by researchers who are considering their choice of animal model in vision sciences research. Content Type Journal ArticlePages 1-8DOI 10.1007/s00417-011-1617-9Authors Irene Sanchez, IOBA-Eye Institute and CIBER-BBN, University of Valladolid, Valladolid, SpainRaul Martin, IOBA-Eye Institute and...
RSS Source:   Med Worm - Glaucoma Thu, 3 Feb 2011 6:14:56 am
Glaucoma - news item 87 of 146
Different spatial and temporal protein expressions of repulsive guidance molecule a and neogenin in the rat optic nerve after optic nerve crush with and without lens injury
In this study, we evaluated the spatial and temporal localization pattern of RGMA and its receptor neogenin in the optic nerve after optic nerve crush (ONC) without or with lens injury (LI) at up to nine time points (6 hr to 20 days) postsurgery by performing immunohistochemistry and Western blots....
RSS Source:   Med Worm - Glaucoma Thu, 3 Feb 2011 12:50:37 am
Glaucoma - news item 88 of 146
Involvement of the CD200 receptor complex in microglia activation in experimental glaucoma.
Authors: Taylor S, Calder CJ, Albon J, Erichsen JT, Boulton ME, Morgan JE The interaction of the myeloid restricted molecule CD200R with its widely expressed ligand CD200 is involved in the down-regulation of microglia activation. In the present study, we examined the involvement of CD200R in microglia activation in experimental...
RSS Source:   Med Worm - Glaucoma Wed, 2 Feb 2011 11:00:00 pm
Glaucoma - news item 89 of 146
Retinal Ganglion Cell Gene Therapy and Visual System Repair.
Authors: Hellström M, Harvey AR Recent clinical trials have shown that the use of replication deficient viral vectors to genetically modify cells in the retina can be of therapeutic benefit in the treatment of certain inherited degenerative conditions that compromise photoreceptor, and hence visual, function. This review is focussed primarily...
RSS Source:   Med Worm - Glaucoma Wed, 2 Feb 2011 11:00:00 pm
Glaucoma - news item 90 of 146
Medical interventions for traumatic hyphema.
Authors: Gharaibeh A, Savage HI, Scherer RW, Goldberg MF, Lindsley K Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye. Hyphema uncommonly causes permanent loss of vision. Associated trauma (e.g., corneal...
RSS Source:   Med Worm - Glaucoma Wed, 2 Feb 2011 3:15:07 pm
Glaucoma - news item 91 of 146
S1P2 receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology.
Authors: Sumida GM, Stamer WD Elevated intraocular pressure is the main risk-factor in primary open-angle glaucoma, involving an increased resistance to aqueous humor outflow in the juxtacanalicular region of the conventional outflow pathway which includes the trabecular meshwork (TM) and the inner wall of Schlemm's canal (SC). Previously, sphingosine-1-phosphate (S1P)...
RSS Source:   Med Worm - Glaucoma Tue, 1 Feb 2011 11:00:00 pm
Glaucoma - news item 92 of 146
Corneal biomechanics measured with the ocular response analyser in patients with unilateral open‐angle glaucoma
Conclusions:  Corneal hysteresis but not corneal resistance factor is dependent on IOP. In patients with unilateral POAG, IOP is higher in the affected eye. When CH is corrected for IOP, corneal biomechanical properties do not differ in both eyes of patients with unilateral POAG. (Source: Acta Ophthalmologica)
RSS Source:   Med Worm - Glaucoma Tue, 1 Feb 2011 11:00:00 pm
Glaucoma - news item 93 of 146
Automated alternation flicker for the detection of optic disc haemorrhages
Conclusion:  Automated alternation flicker was a more sensitive method for disc haemorrhage detection than the current clinical standards and may have an important role in the management of glaucoma. (Source: Acta Ophthalmologica)
RSS Source:   Med Worm - Glaucoma Tue, 1 Feb 2011 11:00:00 pm
Glaucoma - news item 94 of 146
Outcomes of Goniotomy for Primary Congenital Glaucoma in East Africa
Objective: To evaluate the effectiveness of goniotomy to treat primary congenital glaucoma in an east African population.Design: A retrospective series using case records. For patients who underwent goniotomies in both eyes, only the first was analyzed.Participants: Forty-seven children undergoing goniotomy (47/80 operated eyes analyzed). Thirty-six children (77%) were male. Mean...
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 95 of 146
Primary Congenital Glaucoma in the Developing World
Despite its rarity, primary congenital glaucoma and other forms of childhood glaucoma were once a leading cause of admission to schools for the blind in the United States in the first part of the 20th century. Goniotomy and trabeculotomy surgery were introduced in the middle part of the 20th century,...
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 96 of 146
A Simple Vista en Este Número
Mwanza y otros (p. 241) han observado que tanto los parámetros de la cabeza del nervio óptico (ONH) como los de la capa peripapilar de fibras nerviosas de la retina (RNFL), medidos con el HD-OCT (tomografía de coherencia óptica), de Cirrus no sólo permiten diferenciar entre los ojos sanos y...
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 97 of 146
This Issue at a Glance
Mwanza et al (p. 241) have found that both optic nerve head (ONH) and peripapillary retinal nerve fiber layer (RNFL) parameters, as measured by spectral domain Cirrus HD-OCT (optical coherence tomography), cannot only distinguish between healthy and glaucomatous eyes in general, but between healthy and mildly diseased eyes as well....
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 98 of 146
In vitro fluid dynamics of the ahmed glaucoma valve modified with expanded polytetrafluoroethylene.
Conclusions: Modifying the outflow tract of the Ahmed valve with a porous membrane adds resistance that decreases with increasing flow. The Ahmed valve implant behaves as a variable resistor. It is partially open at low pressures and provides reduced resistance at physiologic flow rates. PMID: 21281065 [PubMed - in process] (...
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 99 of 146
Effect of Avosentan (SPP-301) in Porcine Ciliary Arteries.
Conclusions: Avosentan has a strong inhibitory effect on the endothelin-1-induced contractions. Blockade of ET receptors is potentially an attractive target in many eye diseases including glaucoma. Further studies are needed to evaluate the usefulness of endothelin blockers in ophthalmology. PMID: 21281066 [PubMed - in process] (Source: Current Eye Research)
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 100 of 146
Comparison of Goldmann Applanation Tonometer, Noncontact Tonometer, and TonoPen XL for Intraocular Pressure Measurement in Different Types of Glaucomatous, Ocular Hypertensive, and Normal Eyes.
Conclusion:?IOP measurement differences between the three tonometers are affected by age, type of glaucoma, and especially CCT and IOP levels. PMID: 21284505 [PubMed - as supplied by publisher] (Source: Current Eye Research)
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 101 of 146
Implants suggested for glaucoma case.
Authors: Bergman F PMID: 21276569 [PubMed - in process] (Source: Optometry) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 102 of 146
Phacoviscocanalostomy in pseudoexfoliation glaucoma versus primary open-angle glaucoma.
Conclusions: Phacoviscocanalostomy achieved excellent IOP control and VA improvement in both PEXG and POAG groups. PEXG demonstrated greater IOP reduction and fewer postoperative medications than POAG. The complication rate was low and did not affect surgical outcome. Phacoviscocanalostomy can be an effective and safe surgical alternative to phacotrabeculectomy in both...
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 103 of 146
New glaucoma diagnostic technologies: a systematic review of economic studies.
Authors: Tarride JE, Burke N, Hopkins RB, Goeree R, Hodge WG PMID: 21283168 [PubMed - in process] (Source: Canadian Journal of Ophthalmology)
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 104 of 146
High-Resolution Multifocal Pupillographic Objective Perimetry in Glaucoma [Glaucoma]
Conclusions. mfPOP produces separate information on response delay and afferent and efferent defects at every point in the field. The diagnostic accuracy of the 40-region, 150-ms stimulus is comparable to that of commonly used subjective perimeters and encourages further investigation of this technique. (Source: Investigative Ophthalmology)
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 105 of 146
Optineurin in neurodegenerative diseases
This study indicates that optineurin is widely distributed in neurodegenerative conditions; however, its significance is obscure. (Source: Neuropathology)
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 pm
Glaucoma - news item 106 of 146
California physicians sue over glaucoma treatment by optometrists
They say patient safety would be jeopardized because new standards don't call for adequate training. Optometrists say the rules increase access to care. (Source: American Medical News - PROFESSION)
RSS Source:   Med Worm - Glaucoma Mon, 31 Jan 2011 11:00:00 am
Glaucoma - news item 107 of 146
Latanoprost Promotes Neurite Outgrowth in Differentiated RGC-5 Cells via the PI3K-Akt-mTOR Signaling Pathway.
This study presents novel in vitro evidence that latanoprost could promote neurite outgrowth through an FP receptor-mediated modulation of the PI3K-Akt-mTOR signaling pathway. This finding may provide insight into a better understanding of a new mechanism of latanoprost for glaucoma therapy and into the physiological-modulating activities of prostaglandins. PMID: 21279434 [...
RSS Source:   Med Worm - Glaucoma Fri, 28 Jan 2011 11:00:00 pm
Glaucoma - news item 108 of 146
Author response: least invasive option seems best
The patient presented a very complicated case of glaucoma. In such situations, there are often alternate management modalities, and Dr. Bergman suggests a very reasonable option. When a patient presents with a lens-induced glaucoma, it seems intuitive that the best option would be to remove the lens unless there was...
RSS Source:   Med Worm - Glaucoma Fri, 28 Jan 2011 5:47:07 pm
Glaucoma - news item 109 of 146
Endothelin-1 and Nitric Oxide Levels in Patients with Glaucoma
Ophthalmic Res 2011;46:98†102 (DOI:10.1159/000323584) (Source: Karger Publishers)
RSS Source:   Med Worm - Glaucoma Fri, 28 Jan 2011 1:20:07 pm
Glaucoma - news item 110 of 146
Use of the Anterior Chamber Maintainer in Trabeculectomy Following Vitrectomy.
Conclusion: ACM is effective in maintaining IOP and reducing complications during trabeculectomy following vitrectomy, thereby increasing surgical success rates. PMID: 21275521 [PubMed - as supplied by publisher] (Source: Current Eye Research)
RSS Source:   Med Worm - Glaucoma Thu, 27 Jan 2011 11:00:00 pm
Glaucoma - news item 111 of 146
Processing of Optineurin [Neurobiology]
This study thus provides compelling evidence that in a normal homeostatic situation, the turnover of endogenous optineurin involves mainly UPP. When optineurin is up-regulated or mutated, the UPP function is compromised, and autophagy comes into play. A decreased PSMB5 level and an induced autophagy were also demonstrated in vivo in...
RSS Source:   Med Worm - Glaucoma Thu, 27 Jan 2011 11:00:00 pm
Glaucoma - news item 112 of 146
Retinal nerve fiber layer measurement and diagnostic capability of spectral-domain versus time-domain optical coherence tomography.
Conclusions. Retinal nerve fiber layer measurements on the CirrusTM and Stratus® OCT correlate well but do not have clinically acceptable agreement between their measurements. The instruments may not be used interchangeably. PMID: 21279977 [PubMed - as supplied by publisher] (Source: European Journal of Ophthalmology)
RSS Source:   Med Worm - Glaucoma Wed, 26 Jan 2011 11:00:00 pm
Glaucoma - news item 113 of 146
Ultrasound biomicroscopic assessment of angle parameters in patients with primary angle closure glaucoma undergoing phacoemulsification.
Conclusions. Phacoemulsification in eyes with PACG results in significant widening of the anterior chamber angle. This results in better IOP control after surgery and decreases the need for glaucoma medications. These findings are of clinical significance in obviating the need for simultaneous filtering surgery in eyes with PACG undergoing phacoemulsification...
RSS Source:   Med Worm - Glaucoma Wed, 26 Jan 2011 11:00:00 pm
Glaucoma - news item 114 of 146
Letter to the editor: 24-hour versus daytime intraocular pressure phasing in the management of patients with treated glaucoma.
Authors: Mansouri K, Medeiros FA, Weinreb RN PMID: 21270436 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
RSS Source:   Med Worm - Glaucoma Tue, 25 Jan 2011 11:00:00 pm
Glaucoma - news item 115 of 146
On and off responses of the photopic fullfield ERG in normal subjects and glaucoma patients
We examined 19 healthy subjects, 27 patients with glaucomatous optic disc atrophy and 7 ocular hypertensive patients. The amplitudes and implicit times of the on and off responses of the human ERG depended on flash luminance. Comparing patients with glaucoma and healthy subjects for the 60 cd/m² flash, there was...
RSS Source:   Med Worm - Glaucoma Tue, 25 Jan 2011 10:21:33 pm
Glaucoma - news item 116 of 146
Glaucoma Research Foundation Announces 2011 Annual Benefit & Celebration
"Applauding Those Who Give" is the theme of this year's Glaucoma Research Foundation Annual Benefit and Celebration. The dinner, auction, and presentations take place on Wednesday, January 26, 2011 at The Palace Hotel in San Francisco. As the Glaucoma Research Foundation's annual fundraiser, the benefit focuses on recent results from...
RSS Source:   Med Worm - Glaucoma Tue, 25 Jan 2011 12:00:00 pm
Glaucoma - news item 117 of 146
Lack of neuroprotection against experimental glaucoma in c-Jun N-terminal kinase 3 knockout mice.
Authors: Quigley HA, Cone FE, Gelman SE, Yang Z, Son JL, Oglesby EN, Pease ME, Zack DJ To determine if the absence of c-Jun N-terminal kinase 3 (JNK3) in the mouse retina would reduce retinal ganglion cell (RGC) loss in mice with experimental glaucoma. C57BL/6 mice underwent experimental intraocular pressure (...
RSS Source:   Med Worm - Glaucoma Mon, 24 Jan 2011 11:00:00 pm
Glaucoma - news item 118 of 146
A Comparison of Functional and Structural Measures for Identifying Progression of Glaucoma [Glaucoma]
Conclusions. Each test showed evidence of progression in some eyes. However, agreement among tests and stereophotography regarding which eyes showed progression was poor, illustrating the importance of following up patients with a combination of functional and structural tests. (Source: Investigative Ophthalmology)
RSS Source:   Med Worm - Glaucoma Mon, 24 Jan 2011 11:00:00 pm
Glaucoma - news item 119 of 146
Cell Proliferation and Interleukin-6-Type Cytokine Signaling Are Implicated by Gene Expression Responses in Early Optic Nerve Head Injury in Rat Glaucoma [Glaucoma]
Conclusions. Cell proliferation and IL-6–type cytokine gene expression, rather than astrocyte hypertrophy, characterize early pressure-induced ONH injury. (Source: Investigative Ophthalmology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Glaucoma Mon, 24 Jan 2011 11:00:00 pm
Glaucoma - news item 120 of 146
Home Glaucoma Test
(Ivanhoe Newswire) -- They call it the silent killer of vision. (Source: Medical Headlines From Ivanhoe.com)
RSS Source:   Med Worm - Glaucoma Mon, 24 Jan 2011 4:00:00 am
Glaucoma - news item 121 of 146
Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model
AbstractWe investigated whether endoplasmic reticulum (ER) stress was involved in the pathophysiological mechanisms underlying neuronal death of the lateral geniculate nucleus (LGN) after intraocular pressure (IOP) elevation. Five cynomolgus monkeys, four with a glaucomatous left eye after laser photocoagulation treatment and one normal monkey, were studied. At 4, 11, 15...
RSS Source:   Med Worm - Glaucoma Sun, 23 Jan 2011 11:00:00 pm
Glaucoma - news item 122 of 146
The role of blood pressure in glaucoma
Although intraocular pressure (IOP) remains an important risk factor for glaucoma, it is clear that other factors can also influence disease development and progression. More recently, the role that blood pressure (BP) has in the genesis of glaucoma has attracted attention, as it represents a clinically modifiable risk factor and...
RSS Source:   Med Worm - Glaucoma Sun, 23 Jan 2011 11:00:00 pm
Glaucoma - news item 123 of 146
Travoprost/timolol fixed combination in the management of open-angle glaucoma: a clinical review
Expert Opinion on Pharmacotherapy, Volume 12, Issue 3, Page 463-471, February 2011. (Source: Expert Opinion: Expert Opinion on Pharmacotherapy: Table of Contents)
RSS Source:   Med Worm - Glaucoma Sat, 22 Jan 2011 10:34:20 am
Glaucoma - news item 124 of 146
January is Glaucoma Awareness Month
. For more information, visit the MedlinePlus Glaucoma topic page and the National Eye Institute. (Source: What's New on MedlinePlus)
RSS Source:   Med Worm - Glaucoma Fri, 21 Jan 2011 8:39:50 pm
Glaucoma - news item 125 of 146
Rapid, cell-based toxicity screen of potentially therapeutic post-transcriptional gene silencing agents.
Authors: Kolniak TA, Sullivan JM Post-transcriptional gene silencing (PTGS) agents such as antisense, ribozymes and RNA interference (RNAi) have great potential as therapeutics for a variety of eye diseases including retinal and macular degenerations, glaucoma, corneal degenerations, inflammatory and viral conditions. Despite their great potential and over thirty years of...
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 126 of 146
24-Hour intraocular pressure phasing remains an important tool in glaucoma diagnostics.
Authors: Schiefer U, Meisner C, Ziemssen F PMID: 21258077 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 127 of 146
Thyroxin substitution and open-angle glaucoma: a nationwide register-based study on filled prescriptions.
Authors: Calissendorff J, Ljung R PMID: 21258079 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 128 of 146
Persistence of glaucoma medical therapy in the Glasgow Glaucoma Database.
Conclusion The introduction of the first prostaglandin analogue, latanoprost, dramatically improved treatment persistence for glaucoma patients. In the current prostaglandin-rich treatment environment, these data do not show any significant differences between prostaglandins with respect to treatment persistence. PMID: 21258080 [PubMed - as supplied by publisher] (Source: The British Journal of...
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 129 of 146
Cytokine-Dependent ELAM-1 Induction and Concomitant Intraocular Pressure Regulation in Porcine Anterior Eye Perfusion Culture [Glaucoma]
Conclusions. Simultaneous demonstration of IL-1's lowering of IOP and inducing trabecular ELAM-1 was achieved for the first time in one experiment, and its possible implications in the pathogenesis of glaucoma was further emphasized. The involvement of an autocrine feedback loop was confirmed in the porcine system. TGF-β2 constitutes a potent...
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 130 of 146
Retinal Ganglion Cell Loss in a Rat Ocular Hypertension Model Is Sectorial and Involves Early Optic Nerve Axon Loss [Glaucoma]
Conclusions. These data demonstrate that the pattern of RGC loss after laser-induced ocular hypertension in rats is similar to that previously reported in DBA/2J mice. The results support the view that in glaucoma RGC axons are damaged at the optic nerve head and degenerate within the optic nerve before there...
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 131 of 146
Deformation of the Early Glaucomatous Monkey Optic Nerve Head Connective Tissue after Acute IOP Elevation in 3-D Histomorphometric Reconstructions [Glaucoma]
Conclusions. The data suggest that, in monkey EEG, ONH connective tissue hypercompliance may occur only in a subset of eyes and that early ONH connective tissue deformation is maximized in the superior temporal and/or inferior nasal quadrants. (Source: Investigative Ophthalmology)
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 132 of 146
Prevalence of visual impairment, cataract surgery and awareness of cataract and glaucoma in Bhaktapur district of Nepal: The Bhaktapur Glaucoma Study
This study was undertaken to determine the prevalence of visual impairment, cataract surgery and awareness of cataract and glaucoma among subjects residing in this district of Nepal. Methods: Subjects aged 40 years and above was selected using a cluster sampling methodology and a door to door enumeration was conducted for...
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 133 of 146
Assessing the diagnostic validity of a blind register
Conclusions: The blind register diagnoses and legal blindness status are of high accuracy. This information allows useful linkages to other databases for studies of blindness interactions. A regular updating mechanism would improve the future accuracy of this valuable regional asset. The presence of untreated cataract suggests that regular follow‐up and...
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 134 of 146
Preservation of myelinated nerve fibres in advance glaucoma
(Source: Clinical and Experimental Ophthalmology)
RSS Source:   Med Worm - Glaucoma Thu, 20 Jan 2011 11:00:00 pm
Glaucoma - news item 135 of 146
MRI of the Ex-PRESS stainless steel glaucoma drainage device
Conclusions The Ex-PRESS glaucoma drainage device, manufactured from grade 316L stainless steel, does move in the presence of high magnetic fields. The clinical significance of this finding and translation to in vivo conditions are not currently known. Further studies are needed to better understand how patients might be affected by...
RSS Source:   Med Worm - Glaucoma Wed, 19 Jan 2011 11:00:00 pm
Glaucoma - news item 136 of 146
Long-term perimetric fluctuation in patients with different stages of glaucoma
Conclusions In this study, the authors showed that the lower the visual-field defect, the lower was LF, except at stage 5 of GSS2. As test–retest changes exceeding LF could represent a sign of progression, the authors suggest that clinicians using this classification system calculate LF, in order to better differentiate...
RSS Source:   Med Worm - Glaucoma Wed, 19 Jan 2011 11:00:00 pm
Glaucoma - news item 137 of 146
Retinal optical coherence tomography: past, present and future perspectives
Optical coherence tomography (OCT) has undergone substantial changes since its first use in the 1990s. Although the first generation of OCT systems heralded a new era in the non-invasive diagnostic options in ophthalmology, they did not reveal much detail. Later devices offered more information and helped in the diagnosis and...
RSS Source:   Med Worm - Glaucoma Wed, 19 Jan 2011 11:00:00 pm
Glaucoma - news item 138 of 146
Monitoring visual field progression
(Source: British Journal of Ophthalmology)
RSS Source:   Med Worm - Glaucoma Wed, 19 Jan 2011 11:00:00 pm
Glaucoma - news item 139 of 146
Acute bilateral angle-closure glaucoma and choroidal effusion associated with acetazolamide administration after cataract surgery
We present an interventional case report of a 76-year-old man who developed bilateral angle-closure glaucoma with extensive choroidal detachment following administration of oral acetazolamide immediately after routine cataract extraction and intraocular lens implantation. Rapid clinical improvement occurred after acetazolamide was stopped and high-dose intravenous steroid therapy was given. Although extremely...
RSS Source:   Med Worm - Glaucoma Wed, 19 Jan 2011 5:40:28 pm
Glaucoma - news item 140 of 146
Graft Failure After Penetrating Keratoplasty in Eyes With Ahmed Valves
We read with interest the recently published article “Graft Failure after Penetrating Keratoplasty in Eyes with Ahmed Valves,” by Hollander and associates. They concluded that corneal graft failure in eyes with Ahmed valves (AVs) was high. They also report that poor intraocular pressure control may be related to graft failure....
RSS Source:   Med Worm - Glaucoma Wed, 19 Jan 2011 5:39:57 pm
Glaucoma - news item 141 of 146
Yellow-Tinted Intraocular Lenses on Short-Wavelength Automated Perimetry
I read with great interest the article by Jang and associates regarding the effect of yellow-tinted intraocular lenses (IOLs) on short-wavelength automated perimetry (SWAP). The study showed that when SWAP was performed, assuming normal structures in both eyes, mean deviation (MD) and pattern standard deviation (PSD) of eyes implanted with...
RSS Source:   Med Worm - Glaucoma Wed, 19 Jan 2011 5:39:57 pm
Glaucoma - news item 142 of 146
Early microglia activation in a mouse model of chronic glaucoma
AbstractChanges in microglial cell activation and distribution are associated with neuronal decline in the central nervous system (CNS), particularly under pathological conditions. Activated microglia converge on the initial site of axonal degeneration in human glaucoma, yet their part in its pathophysiology remains unresolved. To begin with, it is unknown whether...
RSS Source:   Med Worm - Glaucoma Wed, 19 Jan 2011 4:29:54 pm
Glaucoma - news item 143 of 146
Investors sought for glaucoma test
A home test for glaucoma has been developed by a University of Arizona (UA) engineer and a Phoenix ophthalmologist with funding from the National Science Foundation. The two now are seeking investors to help fund final development and commercialization of the product. (Source: Modern Medicine)
RSS Source:   Med Worm - Glaucoma Tue, 18 Jan 2011 11:00:00 pm
Glaucoma - news item 144 of 146
Investors sought for home glaucoma test
A home test for glaucoma has been developed by a University of Arizona (UA) engineer and a Phoenix ophthalmologist with funding from the National Science Foundation. The two now are seeking investors to help fund final development and commercialization of the product. (Source: Modern Medicine)
RSS Source:   Med Worm - Glaucoma Tue, 18 Jan 2011 1:28:11 pm
Glaucoma - news item 145 of 146
Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma [Neuroscience]
Optic nerve head (ONH) astrocytes have been proposed to play both protective and deleterious roles in glaucoma. We now show that, within the postlaminar ONH myelination transition zone (MTZ), there are astrocytes that normally express Mac-2 (also known as Lgals3 or galectin-3), a gene typically expressed only in phagocytic cells....
RSS Source:   Med Worm - Glaucoma Mon, 17 Jan 2011 11:00:00 pm
Glaucoma - news item 146 of 146
Successful treatment of acquired hemophilia A, complicated by chronic GVHD, with tocilizumab
Abstract A 65-year-old woman who had suffered from chronic graft-versus-host disease (GVHD) presented with extensive purpura and was diagnosed with acquired hemophilia A. Because she was refractory to corticosteroids and her condition was complicated with diabetes mellitus, glaucoma, and hypoglobulinemia, she was treated with tocilizumab. Tocilizumab treatment increased the activity...
RSS Source:   Med Worm - Glaucoma Mon, 17 Jan 2011 7:14:57 pm