Hepatitis - news item 1 of 140
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Rituximab: Hepatitis: case report
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(Source: Reactions)
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RSS Source: Med Worm - Hepatitis Sun, 6 Mar 2011 4:02:10 pm
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Hepatitis - news item 2 of 140
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Paracetamol: Hepatitis: case report
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(Source: Reactions)
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RSS Source: Med Worm - Hepatitis Sun, 6 Mar 2011 4:02:10 pm
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Hepatitis - news item 3 of 140
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U.S. FDA Removes Warning About Potential Liver Injury From Boxed Warning Of Prescribing Information For Gilead's Letairis
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Gilead Sciences, Inc. (Nasdaq: GILD) announced that the U.S. Food and Drug Administration (FDA) has approved a change to the prescribing information for Letairis(R) (ambrisentan 5 mg and 10 mg tablets), the company's once-daily treatment to improve exercise ability and delay clinical worsening in pulmonary arterial hypertension (PAH, WHO Group...
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RSS Source: Med Worm - Hepatitis Sat, 5 Mar 2011 8:00:00 am
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Hepatitis - news item 4 of 140
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Activin a in nonalcoholic Fatty liver disease.
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Authors: Yndestad A, Haukeland JW, Dahl TB, Halvorsen B, Aukrust P Nonalcoholic fatty liver disease (NAFLD) is emerging as one of the most common causes of abnormal liver function. NAFLD is a spectrum of disease ranging from simple steatosis (i.e., fat accumulation) of the liver to nonalcoholic steatohepatitis (NASH) with...
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RSS Source: Med Worm - Hepatitis Fri, 4 Mar 2011 10:00:16 pm
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Hepatitis - news item 5 of 140
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Coumarinâˆ'Purine Ribofuranoside Conjugates as New Agents against Hepatitis C Virus
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Journal of Medicinal ChemistryDOI: 10.1021/jm101337v (Source: Journal of Medicinal Chemistry)
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RSS Source: Med Worm - Hepatitis Fri, 4 Mar 2011 7:23:34 pm
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Hepatitis - news item 6 of 140
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CROI: HCV Drug Seems Safe in HIV Coinfected Patients (CME/CE)
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BOSTON (MedPage Today) -- Early results of a phase II trial suggest a new drug for hepatitis C can be used safely in patients also infected with HIV, a researcher said here. (Source: MedPage Today Meeting Coverage) MedWorm Message: Watch the new MedWorm demo and find out how to get...
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RSS Source: Med Worm - Hepatitis Fri, 4 Mar 2011 4:13:04 pm
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Hepatitis - news item 7 of 140
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New drug regimens cut HIV spread from mother to infant, NIH study shows
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Pregnant women who are unaware they have HIV miss the chance for drug treatment that not only can benefit their own health but could also prevent them from transmitting the virus to their infants. When HIV is not diagnosed until women go into labor, their infants are usually treated soon...
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RSS Source: Med Worm - Hepatitis Fri, 4 Mar 2011 4:00:00 pm
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Hepatitis - news item 8 of 140
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High SVR Rates Observed With Telaprevir + Peginterferon/Ribavirin Regardless of Telaprevir Dosing Frequency or Peginterferon Type
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CCO Slideset - Nearly all patients (96%) assigned to 24 total weeks of therapy based on undetectable HCV RNA from Weeks 4-20 achieved SVR. (Source: Clinical Care Options Hepatitis - HCV)
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RSS Source: Med Worm - Hepatitis Fri, 4 Mar 2011 3:59:41 pm
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Hepatitis - news item 9 of 140
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Kidney Transplant Recipients; Get Moving To Save Your Life
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Low physical activity increases kidney transplant patients' likelihood of dying early, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that patients need to exercise to fend off an early death. Inactive people in general face increased...
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RSS Source: Med Worm - Hepatitis Fri, 4 Mar 2011 10:00:00 am
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Hepatitis - news item 10 of 140
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Not Everyone Treated Equally When It Comes To Kidney Transplantation
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Not all racial and ethnic groups have equal access to kidney transplantation, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results indicate that the reasons for these disparities are varied and that more focused efforts are needed to address...
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RSS Source: Med Worm - Hepatitis Fri, 4 Mar 2011 10:00:00 am
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Hepatitis - news item 11 of 140
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Hepatitis B virus X protein impedes the DNA repair via its association with transcription factor, TFIIH
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Conclusions: We conclude that HBx may act as the promoting factor by inhibiting DNA repair causing DNA damage and accumulation of errors, thereby contributing to HCC development. (Source: BMC Microbiology - Latest articles) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest,...
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 12 of 140
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Development and Validation of a High-Throughput Screening Assay for the Hepatitis C Virus p7 Viroporin
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The HCV p7 protein is not involved in viral RNA replication but is essential for production of infectious virus. Based on its putative ion channel activity, p7 belongs to a family of viral proteins known as viroporins that oligomerize after insertion into a lipid membrane. To screen for compounds capable...
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 13 of 140
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ILâ€32: A new proinflammatory cytokine involved in HCVâ€related liver inflammation and fibrosis
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Conclusion:ILâ€32 is a novel proinflammatory cytokine involved in HCVâ€associated liver inflammation/fibrosis. ILâ€32 is expressed by human hepatocytes and hepatoma cells and its expression is regulated by proinflammatory stimuli. (269 words) (HEPATOLOGY 2011.) (Source: Hepatology)
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 14 of 140
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High predictive accuracy of an unbiased proteomic profile for sustained virologic response in chronic hepatitis C patients
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Conclusion:Our preliminary data indicates that a serumâ€based protein signature can accurately predict treatment response to current SOC in most CHC patients. (HEPATOLOGY 2011.) (Source: Hepatology)
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 15 of 140
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Polymyositis associated with hepatitis B: management with entacavir and prednisolone
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We report a 57â€yearâ€old woman with a 20â€year history of hepatitis B presenting with progressive proximal lower limb weakness for the previous 1 month. Previous medical history included a pericardial and pleural effusion, of which no cause was found and pulmonary tuberculosis which has been adequately treated. Examination revealed multiple telangiactasia...
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 16 of 140
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Atherosclerotic heart disease: prevalence and risk factors in hospitalized men with haemophilia A
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Summary.  Atherosclerotic heart disease (ASHD) is a common cause of morbidity and mortality in Western society. Few studies have determined prevalence and predictors of ASHD in haemophilia (HA), a population whose survival is improving with safer blood products and effective treatments for AIDS and hepatitis C. The purpose of this...
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 17 of 140
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Persistent factor VIII inhibitors and orthopaedic complications in children with severe haemophilia A
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This study aimed to evaluate prevalence of FVIII inhibitors in previously treated children with severe HA and the impact of persistent inhibitors on knee joint status and lumbar bone mineral density (BMD). Fifty children with severe HA, FVIII <1%; aged 5†16 years were enrolled in this study; they received plasmaâ€derived...
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 18 of 140
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New payouts for victims of hepatitis C blood infection
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MORE Scots who were infected with hepatitis C through treatment with NHS blood or blood products will now be eligible for thousands of pounds of extra support. (Source: Scotsman.com News - Health)
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 19 of 140
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Isolation and characterization of two new Hepatitis E Virus Genotype 1 strains from two Mini-outbreaks in Lahore, Pakistan
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Conclusions: Our study suggest that both the human HEV strains were closely related to the Sar-55 but different from the Abb-2B and 87-Pakistan-B HEV isolates sharing 88-91% sequence identity to Pakistani isolate Sar-55. These results indicated that Sar-55 is the main endemic HEV strain in various areas of the country. (...
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 20 of 140
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An immunocompetent adult patient with Hepatitis and Guillain-Barre Syndrome after Cytomegalovirus infection
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Conclusions: This case showed an immunocompetent adult patient with hepatitis and GBS induced by CMV. The physicians should take into account multi-system involvement of severe CMV infection. (Source: Virology Journal)
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 21 of 140
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Trends in prevalence of hepatitis B virus infection among Albanian blood donors, 1999-2009
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Conclusion: The prevalence of HBsAg was lower in voluntary non remunerate blooddonors than commercial donors and family replacement blood donors. In FDs theprevalence was higher than VDs but lower than CDs. So, it is important to encouragethe voluntary blood donors to become regularly blood donors. (Source: Virology Journal) MedWorm Message:...
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 11:00:00 pm
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Hepatitis - news item 22 of 140
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Teva Appeals $500 Million Verdict Over Nightmarish Clinic Practices
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Teva Pharmaceutical Industry has appealed to the Nevada Supreme Court the largest jury verdict of 2010, a $503.5 million whopper it says came down after the trial judge stripped the Israeli drug company of virtually all its defenses. Depending on how the state's highest court rules on this and related...
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 1:33:57 pm
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Hepatitis - news item 23 of 140
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IL28B Gene Predicts Treatment Outcome For Liver Transplantation Patients
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German researchers have found a significant association of IL28B genotypes to interferon-based antiviral treatment outcome, and to graft inflammation caused by hepatitis C virus (HCV). The study determined that the presence of G-allele serves as a marker for severe HCV-induced graft inflammation, as well as a predictor for unsuccessful treatment....
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 10:00:00 am
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Hepatitis - news item 24 of 140
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Simultaneous Occurrence of Pleural Effusion and Interstitial Pneumonitis After Treatment With Pegylated Interferon for Hepatitis C Virus Infection
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This patient with chronic hepatitis C presented with a rare simultaneous occurrence of pleural effusion and interstitial pneumonitis. Was pulmonary toxicity induced by interferon therapy? Southern Medical Journal (Source: Medscape Pharmacist Headlines)
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 3:00:00 am
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Hepatitis - news item 25 of 140
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9 Ohio veterans test positive for hepatitis
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Nine Ohio veterans have tested positive for hepatitis after undergoing routine dental work at a Dayton clinic, according to Ohio Veterans Affairs Communications Officer Todd Sledge. (Source: CNN.com - Health)
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RSS Source: Med Worm - Hepatitis Thu, 3 Mar 2011 1:07:20 am
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Hepatitis - news item 26 of 140
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Managing chronic hepatitis B: A qualitative study exploring the perspectives of people living with chronic hepatitis B in Australia
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Conclusions: People with CHB need culturally and linguistically appropriate education and information, particularly at the point of diagnosis. Primary health care professionals need the knowledge, skills and motivation to provide appropriate information to people with CHB, to ensure they have the capacity to better manage their infection. (Source: BMC Research...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 pm
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Hepatitis - news item 27 of 140
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Irritability: an underappreciated side effect of interferon treatment for chronic hepatitis C?
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Conclusion.  Irritability is an underappreciated psychological side effect of interferon therapy. Although irritability is recognised as a side effect of interferon, there is considerable discordance between clinical observation, patient reports and research evidence as reported in the literature. (Source: Journal of Clinical Nursing)
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 pm
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Hepatitis - news item 28 of 140
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High Hepatitis B Immunity in U.S. Children, Adolescents
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Children and adolescents in the United States have high rates of immunity against hepatitis B virus, although adults have much lower rates, according to a study published in the March 1 issue of the Annals of Internal Medicine. (Source: Modern Medicine)
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 pm
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Hepatitis - news item 29 of 140
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Treatment failure and resistance with direct acting antiviral drugs against hepatitis C virus
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This article reviews patterns of resistance to hepatitis C virus direct acting antiviral drugs in development, the mechanisms underlying treatment failure when these drugs are combined with pegylated interferonâ€Î± and ribavirin, the consequences of treatment failure, and possible means of optimizing therapies using direct acting antivirals in the future. (HEPATOLOGY...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 pm
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Hepatitis - news item 30 of 140
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Erratum to: Hepatology. 2008 Feb;47(2):396â€406. CD161 expression on hepatitis C virusâ€specific CD8+ T cells suggests a distinct pathway of T cell differentiation
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(Source: Hepatology)
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 pm
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Hepatitis - news item 31 of 140
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Occult and previous hepatitis B virus infection are not associated with hepatocellular carcinoma in us patients with chronic hepatitis C
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Conclusion:Although almost half the patients in the HALTâ€C Trial had serological evidence of previous HBV infection there was no difference in prevalence of antiâ€HBc in serum or HBV DNA in liver between patients who did or did not develop HCC. In the United States, neither previous nor occult HBV infection...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 pm
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Hepatitis - news item 32 of 140
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Should patients with abnormal liver function tests in primary care be tested for chronic viral hepatitis: cost minimisation analysis based on a comprehensively tested cohort.
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Conclusions: Based on this analysis and on widely accepted clinical principles, a "fast and frugal" heuristic was produced to guide general practitioners with respect to diagnosing cases of viral hepatitis in asymptomatic patients with abnormal LFTs. It recommends testing all patients where a clear clinical indication of infection is present (...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 pm
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Hepatitis - news item 33 of 140
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Hepatitis A outbreak predominantly affecting men who have sex with men in Northern Ireland, October 2008 to July 2009
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(Source: Eurosurveillance latest news)
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 pm
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Hepatitis - news item 34 of 140
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Infected blood inquiry in city
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A PUBLIC inquiry into how blood transfusion patients contracted HIV and hepatitis C is to take place in Edinburgh next week. (Source: Scotsman.com News - Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 pm
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Hepatitis - news item 35 of 140
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U.S. Adults Still Have Low Rates of HBV Immunity
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Kids in the U.S. these days are largely immune to the hepatitis B virus (HBV), but high-risk adults still have low vaccination rates, according to a new study. Reuters Health Information (Source: Medscape Allergy Headlines)
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 6:50:27 pm
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Hepatitis - news item 36 of 140
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Community-Acquired MRSA Pyomyositis: Case Report and Review of the Literature
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We report the case of a 46-year-old gentleman with a history of untreated, uncomplicated Hepatitis C who presented with a 2-month history of back pain and was found to have abscesses in his psoas and right paraspinal muscles with subsequent lumbar spine osteomyelitis. Despite drainage and appropriate antibiotic management the...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 4:46:35 pm
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Hepatitis - news item 37 of 140
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Torsade de Pointes due to Methadone Use in a Patient with HIV and Hepatitis C Coinfection
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We present a case of Torsade de Pointes secondary to multiple factors including patient susceptibility and iatrogenic influences. Contributing causes are presented, and the approach to treatment is discussed. (Source: Anesthesiology Research and Practice)
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 2:47:49 pm
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Hepatitis - news item 38 of 140
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Chronic Elevation of Liver Enzymes in Acute Intermittent Porphyria Initially Misdiagnosed as Autoimmune Hepatitis
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We describe a 32-year-old woman with elevated transaminases, autoantibodies, and a liver biopsy result suggestive of autoimmune hepatitis. The indicated treatment was administered without showing a satisfactory response. The patient had a family history of acute intermittent porphyria (AIP) so we decided to begin treatment with hematin, achieving a complete...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 2:47:49 pm
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Hepatitis - news item 39 of 140
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Huge Implications Of Discovery Of Hormone Pathway To Fatty Liver Disease
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Scientists at the UCSF Cardiovascular Research Institute have discovered how a change in growth hormone activity in mice leads to fatty liver disease, a condition whose human counterpart is of rising concern worldwide. Disruption of a key protein in the pathway that responds to growth hormone could explain how fatty...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 am
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Hepatitis - news item 40 of 140
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News From The Journal Of Clinical Investigation: March 1, 2011
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METABOLISM - New mechanism explains the role of growth hormone in fatty liver Non-alcoholic fatty liver disease (NAFLD) is a common condition that is linked to obesity and insulin resistance. If left untreated, this build up of fat deposits within the liver cells can lead to fibrosis and scarring of...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 am
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Hepatitis - news item 41 of 140
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BARACLUDE(R) (entecavir) Approved By The European Commission For The Treatment Of Chronic Hepatitis B In Adult Patients
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Bristol-Myers Squibb (NYSE: BMY) announced that BARACLUDE(R) (entecavir) has been approved by the European Commission on February 28th 2011 to treat chronic hepatitis B (CHB) in adult patients with evidence of decompensated liver disease. BARACLUDE(r) was already approved in Europe in June 2006 for use in adult patients with CHB...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 11:00:00 am
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Hepatitis - news item 42 of 140
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BARACLUDE(R) (Entecavir) Approved By The European Commission For The Treatment Of CHB In Adult Patients With Evidence Of Decompensated Liver Disease
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Bristol-Myers Squibb (NYSE:BMY) announced that BARACLUDE® (entecavir) has been approved by the European Commission on February 28th 2011 to treat chronic hepatitis B (CHB) in adult patients with evidence of decompensated liver disease. BARACLUDE(R) was already approved in Europe in June 2006 for use in adult patients with CHB with...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 8:00:00 am
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Hepatitis - news item 43 of 140
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Towards a More Coordinated Federal Response to Improving HIV Prevention and Sexual Health among Men Who Have Sex with Men
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Content Type Journal ArticlePages 1-5DOI 10.1007/s10461-011-9908-zAuthors Dianne Rausch, Division of AIDS Research, National Institutes of Mental Health, National Institutes of Health, Bethesda, USACarl Dieffenbach, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USALaura Cheever, HIV/AIDS Bureau, Health Resources and Services Administration, Rockville, USAKevin...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 6:47:32 am
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Hepatitis - news item 44 of 140
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Metachronous multiple adenocarcinomas of the pancreas
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We report a rare case of metachronous multiple adenocarcinoma of the pancreas. A 59-year-old Japanese man visited our institute for a routine workup as a hepatitis C virus carrier, resulting in detection of a 3-cm tumor in the pancreatic body by screening echogram. Results from several imaging modalities were consistent...
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RSS Source: Med Worm - Hepatitis Wed, 2 Mar 2011 6:09:30 am
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Hepatitis - news item 45 of 140
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Impact of Acute Hepatitis A Virus (HAV) Infection on HIV Viral Load in HIV-Infected Patients and Influence of HIV Infection on Acute HAV Infection
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Conclusions: Acute HAV infection may have an impact on HIV VL. The interactions between the 2 viruses may not only prolong the HAV viremia, with a potential increase in the transmission of infection, but the impact on HIV may increase the risk of HIV transmission. Studies with higher sample size...
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RSS Source: Med Worm - Hepatitis Tue, 1 Mar 2011 11:00:00 pm
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Hepatitis - news item 46 of 140
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Effect of interferon treatment on hearing of patients with chronic Hepatitis C
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Conclusions: Our results indicate that PEG-IFN\RBV therapy does not have any impact on the hearing thresholds of patients with HCV. (Source: The Saudi Journal of Gastroenterology)
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RSS Source: Med Worm - Hepatitis Tue, 1 Mar 2011 11:00:00 pm
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Hepatitis - news item 47 of 140
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Plasma carnitine is associated with fatigue in chronic hepatitis C but not in the irritable bowel syndrome
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Conclusions  In patients with chronic hepatitis C, the severity of fatigue is associated with a low level of carnitine, suggesting that an oral supplementation may be effective to relieve fatigue in chronic hepatitis C. The underlying mechanism of fatigue in IBS does not seem to involve carnitine. (Source: Alimentary Pharmacology...
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RSS Source: Med Worm - Hepatitis Tue, 1 Mar 2011 11:00:00 pm
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Hepatitis - news item 48 of 140
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Tenofovir gel protects rectal tissue against HIV, UCLA-led study finds
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This study is the first clinical trial of tenofovir gel for rectal use. Last year, tenofovir gel was shown in a separate trial to reduce the risk of HIV infection in women who used it before and after vaginal sex. Conducted at UCLA and the University of Pittsburgh, the current...
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RSS Source: Med Worm - Hepatitis Tue, 1 Mar 2011 7:00:00 pm
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Hepatitis - news item 49 of 140
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Comparable Ten-Year Outcome in Hemodialysis Patients with Hepatitis C Virus and Hepatitis B Virus Coinfection and Single Hepatitis B Virus Infection
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Blood Purif 2011;32:89†95 (DOI:10.1159/000324196) (Source: Karger Publishers)
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RSS Source: Med Worm - Hepatitis Tue, 1 Mar 2011 4:07:56 pm
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Hepatitis - news item 50 of 140
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Slideset: Future Generations: Understanding the Similarities and Differences Among Direct-Acting Antivirals for Hepatitis C
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CCO Slideset - Stefan Zeuzem, MD, describes the development of new classes of drugs for treatment of patients with hepatitis C infection and reviews parameters that will govern the use of these drugs. (Source: Clinical Care Options Hepatitis - HCV) MedWorm Message: Watch the new MedWorm demo and find out...
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RSS Source: Med Worm - Hepatitis Tue, 1 Mar 2011 3:43:08 pm
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Hepatitis - news item 51 of 140
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Protein nanotubes trap viruses
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Nanotubes made from human proteins used to ensnare hepatitis B (Source: Chemistry World | Latest News)
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RSS Source: Med Worm - Hepatitis Tue, 1 Mar 2011 8:34:06 am
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Hepatitis - news item 52 of 140
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Resection of a Transplantable Single-Nodule Hepatocellular Carcinoma in Child-Pugh Class A Cirrhosis: Factors Affecting Survival and Recurrence
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Conclusions R0 resection for HCC on compensated cirrhosis may offer good long-term survival in the absence of satellites nodules and macrovascular invasion. Thus, a “first approach†resection is proposed with the possibility of “salvage transplantation.†In other cases, resection may be a bridge to transplantation (“transplantation de principeâ€). Content Type...
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RSS Source: Med Worm - Hepatitis Tue, 1 Mar 2011 6:07:46 am
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Hepatitis - news item 53 of 140
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Sequence heterogeneity of NS5A and core proteins of hepatitis C virus and virological responses to pegylatedâ€interferon/ribavirin combination therapy
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In conclusion, sequence heterogeneity within the IRRDR and ISDR, and a single point mutation at position 70 of the core region of HCVâ€1b are likely to be correlated with virological responses to PEGâ€IFN/RBV therapy. (Source: Microbiology and Immunology)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 54 of 140
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Optimal duration of treatment for acute hepatitis c in human immunodeficiency virus†positive individuals?
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(Source: Hepatology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 55 of 140
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Further analysis is required to identify an early stopping rule for peginterferon therapy that is valid for all hepatitis B e antigen†positive patients
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(Source: Hepatology)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 56 of 140
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Triglyceride synthesis and hepatitis C virus production: Identification of a novel host factor as antiviral target
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(Source: Hepatology)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 57 of 140
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IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection
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Conclusion: Polymorphisms near the IL28B gene show association with rapid viral response but not sustained viral response to PEGâ€IFN/ribavirin therapy in HCV genotype 3â€infected patients. (HEPATOLOGY 2011;) (Source: Hepatology)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 58 of 140
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Mutations selected in the hepatitis C virus NS3 protease domain during sequential treatment with boceprevir with and without pegylated interferon alfaâ€2b
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Summary.  Treatment with hepatitis C virus (HCV)â€NS3â€protease inhibitors lead to the selection of resistant variants. Viral kinetics and resistance profiles in patients who are reâ€treated with the same protease inhibitor are unknown. Viral kinetics and NS3â€resistance mutations obtained by clonal sequencing of the NS3â€protease were analyzed in nine HCVâ€genotypeâ€1â€infected nonresponder...
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 59 of 140
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Discriminant value of serum HBV DNA levels as predictors of liver fibrosis in chronic hepatitis B
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Summary.  Current guidelines recommend antiviral therapy in chronic hepatitis B (HBV) patients with significant histological disease. We aimed to compare histological fibrosis (METAVIR, ≥F2) in patients with HBV DNA ≥20 000 IU/mL vs≥2000 IU/mL and identify predictors of fibrosis. We performed prospective liver biopsies on 203 HBeAgâ€negative patients in four groups: Group I (...
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 60 of 140
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Hepatitis C virus persistence after sustained virological response to antiviral therapy in patients with or without past exposure to hepatitis B virus
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In conclusion, the prevalence of OCI after SVR is comparable in individuals with or without past exposure to HBV. HCV loads and liver alterations in OCI appear to be unaffected by lowâ€level HBV DNA carriage. (Source: Journal of Viral Hepatitis)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 61 of 140
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Frequency and clinical outcomes of flares related to nucleos(t)ide analogue therapy in patients with chronic hepatitis B
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In this study, flares related to NA therapy never led to immune control and sustained disease remission, and sometimes resulted in decompensated liver disease. (Source: Journal of Viral Hepatitis)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 62 of 140
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Human genetic susceptibility to intracellular pathogens
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Summary:  Intracellular pathogens contribute to a significant proportion of infectious disease morbidity and mortality worldwide. Increasing evidence points to a major role for host genetics in explaining interâ€individual variation in susceptibility to infectious diseases. A number of monogenic disorders predisposing to infectious disease have been reported, including susceptibility to intracellular...
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 63 of 140
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Association of IL28B gene variations with mathematical modeling of viral kinetics in chronic hepatitis C patients with IFN plus ribavirin therapy [Medical Sciences]
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In conclusion, Taiwanese patients with CHC receiving Peg-IFN plus ribavirin therapy have a lower daily viral production rate than Western patients, and the rs8099917 TT genotype may contribute to the increased viral clearance rate and better virological responses in these patients. (Source: Proceedings of the National Academy of Sciences)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 64 of 140
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Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication.
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In HIV-1 infected patients, increase of liver enzymes may be mainly due to viral coinfections, alcohol intake, hepatotoxic drugs or autoimmune diseases. Three cases of aminotransferase elevation occurred during a phase of uncontrolled viral replication combined with a severe immunodeficiency and resolved by an effective HAART are described, focusing on...
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 65 of 140
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The DRESS Syndrome: The Great Clinical Mimicker
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We describe a 44-year-old woman who was brought to the emergency department with new-onset hemorrhagic stroke. She was admitted to the intensive care unit where she received supportive care that included clonidine and hydralazine for blood pressure control and phenytoin for seizure prophylaxis. On hospital day 21, the patient developed...
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 66 of 140
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Clinical Implications of the Nelfinavir-Proton Pump Inhibitor Drug Interaction in Patients with Human Immunodeficiency Virus
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Conclusion. Use of PPIs should be minimized or avoided in patients who have attained an undetectable HIV viral load while taking a nelfinavir-based antiretroviral regimen. However, concomitant use of these drugs may be acceptable for indications where PPIs are required for fewer than 30 days. (Source: Pharmacotherapy: Official Journal of...
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 11:00:00 pm
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Hepatitis - news item 67 of 140
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Hepatitis B Rates Drop Among Kids Due To Effective Vaccination Programs, More Efforts Needed For Adults
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Approximately 5.1% of the American population had been exposed to HBV (Hepatitis B virus) between 1988 and 1994, researchers wrote in Annals of Internal Medicine. Since that date, extensive vaccination campaigns for children, as well as education about safe practices should have led to a drop in HBV infection rates....
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 9:00:00 pm
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Hepatitis - news item 68 of 140
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Nearly $1 Million To Improve HBV And HCV Awareness, Prevention And Care In China And India Awarded By Bristol-Myers Squibb Foundation
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The Bristol-Myers Squibb Foundation has awarded four new grants to help improve awareness, prevention and care of hepatitis B (HBV) and hepatitis C (HCV) in China and India. The grants total nearly $1 million USD and bring the Foundation's commitment to reducing hepatitis-related health disparities in Asia to $8 million...
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 7:00:00 am
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Hepatitis - news item 69 of 140
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B
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In conclusion, FibroTest and LSM were the most validated biomarkers of fibrosis in CHB. However, the reliability of Fibroscan must be better assessed. Content Type Journal ArticlePages 1-11DOI 10.1007/s11901-011-0096-0Authors Thierry Poynard, Assistance Publique Hôpitaux de Paris-University Pierre et Marie Curie, Liver Center, Groupe Hospitalier Pitié Salpêtrière, 75013 Paris, FranceYen Ngo,...
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 5:43:52 am
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Hepatitis - news item 70 of 140
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Make the diagnosis, Sherlock!
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Life in the Fast Lane recently posted a neat clinical challenge featuring a young man with abnormal liver enzymes. Light up your meerschaum and see if you can make the diagnosis. (Source: The Poison Review)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 3:45:36 am
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Hepatitis - news item 71 of 140
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HBV-specific T-cell Responses in Healthy Seronegative Sexual Partners of Patients With Chronic HBV Infection
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This study looks at the ways to prevent transmission of hepatitis B, particularly sexual transmission. Journal of Viral Hepatitis (Source: Medscape Gastroenterology Headlines)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 3:00:00 am
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Hepatitis - news item 72 of 140
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Long-term Follow-up of Patients With Hepatitis B e Antigen Negative Chronic Hepatitis B
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How can future liver disease be predicted in certain patients with chronic hepatitis B? Journal of Gastroenterology and Hepatology (Source: Medscape Today Headlines)
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RSS Source: Med Worm - Hepatitis Mon, 28 Feb 2011 3:00:00 am
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Hepatitis - news item 73 of 140
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Parenchymal expression of CD40 exacerbates adenovirusâ€induced hepatitis
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Conclusion:Our results demonstrated that hepatic CD40 expression does not accelerate adenoviral clearance, but rather exacerbates liver injury. This study unveils a previously unknown deleterious effect of hepatic CD40 in adenovirusâ€induced liver inflammation. (HEPATOLOGY 2011.) (Source: Hepatology)
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RSS Source: Med Worm - Hepatitis Sun, 27 Feb 2011 11:00:00 pm
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Hepatitis - news item 74 of 140
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PNPLA3 genotype and hepatocellular carcinoma in chronic hepatitis C
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(Source: Hepatology)
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RSS Source: Med Worm - Hepatitis Sun, 27 Feb 2011 11:00:00 pm
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Hepatitis - news item 75 of 140
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Estimating the net contribution of IL28B variation to spontaneous hepatitis C virus clearance
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Conclusions:We identified IL28B haplotypes highly predictive of spontaneous HCV clearance. The high linkage disequilibrium between IL28B SNPs indicates that association studies need to be complemented by functional experiments to identify single causal variant(s). The point estimate for the genetic effect was higher in the single source cohort, which effectively controls...
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RSS Source: Med Worm - Hepatitis Sun, 27 Feb 2011 11:00:00 pm
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Hepatitis - news item 76 of 140
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Employers in China flout laws which ban the testing of employees for hepatitis B
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(Source: BMJ Online First) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Hepatitis Sun, 27 Feb 2011 11:00:00 pm
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Hepatitis - news item 77 of 140
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Hepatitis Associated Aplastic Anemia: A review
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Hepatitis-associated aplastic anemia (HAAA) is an uncommon but distinct variant of aplastic anemia in which pancytopenia appears two to three months after an acute attack of hepatitis. HAAA occurs most frequently in young male children and is lethal if leave untreated. The etiology of this syndrome is proposed to be...
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RSS Source: Med Worm - Hepatitis Sun, 27 Feb 2011 11:00:00 pm
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Hepatitis - news item 78 of 140
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Tribulus terrestris: Acute kidney injury, hepatitis and seizures: case report
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(Source: Reactions)
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RSS Source: Med Worm - Hepatitis Sun, 27 Feb 2011 5:11:29 pm
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Hepatitis - news item 79 of 140
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Corticosteroids: Hepatitis B reactivation: 12 case reports
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(Source: Reactions) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Hepatitis Sun, 27 Feb 2011 5:11:29 pm
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Hepatitis - news item 80 of 140
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BCG: Granulomatous hepatitis following intravesicular administration in an elderly patient: case report
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(Source: Reactions)
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RSS Source: Med Worm - Hepatitis Sun, 27 Feb 2011 5:11:29 pm
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Hepatitis - news item 81 of 140
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Elderly And Disabled STD Testing Considered By Medicare And Medicaid Services
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Apart from already covering beneficiaries for HIV tests, CMS (Centers for Medicare and Medicaid Service) says it is considering whether to cover screenings for other STDs, such as chlamydia, syphilis, hepatitis B, and gonorrhea. CMS is also considering paying for preventive counseling. In the USA approximately 39 million elderly people...
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RSS Source: Med Worm - Hepatitis Sat, 26 Feb 2011 8:00:00 pm
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Hepatitis - news item 82 of 140
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Investigation of Interferon-α Response by a Single Amino Acid Substitution of Nonstructural Protein 5A in Hepatitis C Virus-Infected Patients
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Journal of Interferon & Cytokine Research , Vol. 0, No. 0. (Source: Journal of Interferon)
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RSS Source: Med Worm - Hepatitis Sat, 26 Feb 2011 3:01:50 am
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Hepatitis - news item 83 of 140
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Kaposi's sarcomaâ€associated herpesvirus infection in Chinese patients with chronic hepatitis B
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AbstractThe seroprevalence of Kaposi's sarcomaâ€associated herpesvirus (KSHV) in Chinese patients with chronic hepatitis B, the relationship between KSHV and hepatitis B virus (HBV) infection, and the influence of glycyrrhizic acid on KSHV replication in vivo are undefined. Plasma was collected from 211 patients with chronic hepatitis B. Antibody to KSHV...
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RSS Source: Med Worm - Hepatitis Sat, 26 Feb 2011 12:35:40 am
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Hepatitis - news item 84 of 140
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U.S. May Pay for Sex Disease Tests for Elderly
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U.S. health officials are considering including tests for sexually transmitted diseases like syphilis and hepatitis B for the elderly and disabled covered under Medicare. Reuters Health Information (Source: Medscape ObGyn and Womens Health Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very...
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 10:02:57 pm
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Hepatitis - news item 85 of 140
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Adding Telaprevir Shortens HCV Treatment for Many
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Adding telaprevir to interferon alfa and ribavirin shortens primary treatment for hepatitis C virus (HCV) type 1, no matter whether telaprevir is given two or three times a day, a multicenter study shows. Reuters Health Information (Source: Medscape Pharmacist Headlines)
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 10:02:56 pm
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Hepatitis - news item 86 of 140
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Study looks at how homeless kids' use of online social networks can affect sexual behavior
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A new UCLA AIDS Institute study suggests that the use of social networking websites by homeless youth can lead to an increase in risky sexual behaviors. But interestingly, homeless kids who used these sites were also more likely to have been tested for sexually transmitted infections and to be better...
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 10:00:00 pm
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Hepatitis - news item 87 of 140
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Hepatitis C virus†associated polyarteritis nodosa
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ConclusionHCVâ€PAN accounts for 19.3% of our cohort of HCV vasculitis. HCVâ€PAN displays a more severe and acute clinical presentation and a higher rate of clinical remission. (Source: Arthritis Care and Research)
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 8:24:51 pm
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Hepatitis - news item 88 of 140
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Scripps Pioneers Individualized Medicine by Offering Genetic Testing to Hepatitis C Patients
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SAN DIEGO, Feb. 25, 2011 (GLOBE NEWSWIRE) -- Scripps Health is one of the first health systems in the United States to offer genetic testing as part of its care for hepatitis C patients planning to undergo drug treatment. (Source: Medical News (via PRIMEZONE))
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 4:52:00 pm
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Hepatitis - news item 89 of 140
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What is expected from the pathologist in the diagnosis of viral hepatitis?
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Abstract The clinician expects from the pathologist a clinically relevant diagnosis on the basis of liver biopsy interpretation. Today, a liver biopsy, as invasive procedure, is only justified when a significant benefit for the patient can be expected particularly with respect to the clinical management. Consequently, liver biopsy is usually...
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 4:07:04 pm
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Hepatitis - news item 90 of 140
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Organs-on-a-Chip for Faster Drug Development
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One of the most challenging aspects of drug development is testing. Scientists are forced either to experiment on whole animals, which is expensive, raises ethical issues and may not predict effects in humans, or to perform tests on microscopic human cells found in tissue cultures, which have been altered to...
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 12:00:00 pm
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Hepatitis - news item 91 of 140
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Lack Of Health Insurance Limits Hepatitis C Patients' Access To Latest Antiviral Therapy
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New research has determined that patients in the U.S. with hepatitis C virus (HCV) are twice as likely to not have health insurance coverage compared with those without the disease. In fact researchers found only a third of HCV infected Americans have access to antiviral therapy; the remaining are either...
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 12:00:00 pm
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Hepatitis - news item 92 of 140
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Mice Protected From Hepatitis C Virus Using New Vaccine Technology
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Three percent of the world's population is currently infected by hepatitis C. The virus hides in the liver and can cause cirrhosis and liver cancer, and it's the most frequent cause of liver transplants in Denmark. Since the virus mutates strongly, we have no traditional vaccine, but researchers at the...
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 9:00:00 am
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Hepatitis - news item 93 of 140
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Fatty Liver May Herald Impending Type 2 Diabetes
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A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that individuals with fatty liver were five times more likely to develop type 2 diabetes than those without fatty liver. This higher risk seemed to occur regardless of the patient's fasting insulin...
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 8:00:00 am
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Hepatitis - news item 94 of 140
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Medical Groups Warn Of Climate Change's Potential Impact on Health
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Title: Medical Groups Warn Of Climate Change's Potential Impact on HealthCategory: Health NewsCreated: 2/24/2011 8:05:00 PMLast Editorial Review: 2/25/2011 (Source: MedicineNet Hepatitis C General)
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RSS Source: Med Worm - Hepatitis Fri, 25 Feb 2011 6:00:00 am
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Hepatitis - news item 95 of 140
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Early activation of p38 mitogen activated protein kinase is associated with interferon-alpha-induced depression and fatigue.
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Authors: Felger JC, Alagbe O, Pace TW, Woolwine BJ, Hu F, Raison CL, Miller AH Cytokine-induced stimulation of p38 mitogen activated protein kinase (MAPK) has been shown to influence behaviorally-relevant pathophysiologic pathways including monoamine neurotransmission and neuroendocrine function and thus may contribute to behavioral changes that occur during chronic administration...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 11:00:00 pm
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Hepatitis - news item 96 of 140
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Psychiatrists' knowledge and practices in screening and assessment of Hepatitis C for inpatients with severe mental illness.
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Conclusion: Improving knowledge about HCV, especially current management, may facilitate better health care for patients with severe mental illness. PMID: 21348789 [PubMed - as supplied by publisher] (Source: Australasian Psychiatry)
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 11:00:00 pm
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Hepatitis - news item 97 of 140
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Republished paper: Managing HBV in patients with impaired immunity
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Chronic hepatitis B is one of the most common infectious diseases worldwide. In patients with an impaired immune system the prevalence of HBsAg is even higher and the course of hepatitis B infection is often aggravated. In HIV/HBV co-infected patients, liver related morbidity and mortality can be reduced by implementing...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 11:00:00 pm
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Hepatitis - news item 98 of 140
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Hepatitis E virus ORF3 antigens derived from genotype 1 and 4 viruses are detected with varying efficiencies by an antiâ€hev enzyme immunoassay
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AbstractThe function of the hepatitis E virus (HEV) open reading frame 3 (ORF3) protein product remains unclear but it is able to induce a strong antibody response following HEV infection. Therefore, it has been used in some enzyme immunoassays (EIAs) for detecting antiâ€HEV antibody. In order to evaluate the difference...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 11:00:00 pm
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Hepatitis - news item 99 of 140
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Association of IL28B variants with response to pegylatedâ€interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b
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In conclusion, ILâ€28B polymorphism affects responses to PEGâ€IFNâ€based treatment in difficultâ€toâ€treat HCV patients. J. Med. Virol. © 2011 Wileyâ€Liss, Inc. (Source: Journal of Medical Virology)
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 11:00:00 pm
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Hepatitis - news item 100 of 140
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Motherâ€toâ€infant transmission of hepatitis B virus: A chinese experience
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AbstractOver 90% of infants infected with hepatitis B virus (HBV) caused by motherâ€toâ€infant transmission will evolve to carrier status, and this cannot be prevented until widespread administration of the HB vaccine and hepatitis B immune globulin (HBIG) is implemented. This prospective study of 214 infants born to HBsAgâ€positive mothers was...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 11:00:00 pm
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Hepatitis - news item 101 of 140
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Impact of universal vaccination on intrafamilial transmission of hepatitis B virus
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In conclusion, this small study showed that both maternal and paternal transmissions are important of the intrafamilial spread of HBV infection. In addition, the introduction of HBV vaccination has resulted in a reduction of intrafamilial transmission, but a study of a large population is needed. J. Med. Virol. © 2011...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 11:00:00 pm
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Hepatitis - news item 102 of 140
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Identification of T cell epitopes on soluble liver antigen in Chinese patients with autoâ€immune hepatitis
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Conclusion: T cell response to SLA in Chinese patients with AIH is broad and associated with hepatocyte damage. (Source: Liver International) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 11:00:00 pm
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Hepatitis - news item 103 of 140
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Risk of Occult Hepatitis B Virus Infection From Blood Transfusion Is Low
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The transmissibility of occult hepatitis B virus (HBV) infection by blood transfusion from patients appears to be quite low, according to findings published in the January 18th online Clinical Infectious Diseases. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 6:30:52 pm
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Hepatitis - news item 104 of 140
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Association between occult hepatitis B infection and the risk of hepatocellular carcinoma: a metaâ€analysis
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Conclusion: Our findings suggest that occult HBV infection was associated with an increased risk of HCC. Occult HBV may serve as a cofactor in the development of HCVâ€related HCC, and it may also play a direct role in promoting Nonâ€B and Nonâ€C HCC growth. Suggestive evidence indicates that individuals with...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 4:05:19 pm
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Hepatitis - news item 105 of 140
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New vaccine technology protects mice from hepatitis C virus
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HCV mutates so strongly that traditional vaccines are useless. However, researchers have now developed a vaccine, which provides future hope for medical protection from the hepatitis C virus. (Source: ScienceDaily Headlines)
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 9:00:00 am
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Hepatitis - news item 106 of 140
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Future Generations: Understanding the Similarities and Differences Among Direct-Acting Antivirals for Hepatitis C
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Resource - Stefan Zeuzem, MD, reviews the characteristics of directly acting antivirals currently in development and discusses the role these agents may have in future combination regimens for HCV. (Source: Clinical Care Options Hepatitis - HCV)
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 8:30:51 am
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Hepatitis - news item 107 of 140
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Nanotechnology May Lead To New Treatment Of Liver Cancer
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Nanotechnology may open a new door on the treatment of liver cancer, according to a team of Penn State College of Medicine researchers. They used molecular-sized bubbles filled with chemotherapy drugs to prevent cell growth and initiate cell death in test tubes and mice. Researchers evaluated the use of molecular-sized...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 7:00:00 am
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Hepatitis - news item 108 of 140
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The role of iron in tumour cell proliferation
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Abstract Iron has a pivotal role in homeostasis due to its participation in virtually all of the body’s oxidationreduction processes. However, iron can also be considered a double-edged weapon, as its excess may lead to an increased risk of developing cancer, presumably by the generation of reactive oxygen species, and...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 6:37:56 am
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Hepatitis - news item 109 of 140
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Timely Care May Be Key to Treating Infected Cuts
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Title: Timely Care May Be Key to Treating Infected CutsCategory: Health NewsCreated: 2/23/2011 8:05:00 PMLast Editorial Review: 2/24/2011 (Source: MedicineNet Hepatitis C General)
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 6:00:00 am
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Hepatitis - news item 110 of 140
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Safety and efficacy of treatment for chronic hepatitis C with a focus on pegylated interferons: the backbone of therapy today and in the future
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Expert Opinion on Drug Safety, Volume 0, Issue 0, Page 1-16, Early Online. (Source: Expert Opinion: Expert Opinion on Drug Safety: Table of Contents)
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 5:09:16 am
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Hepatitis - news item 111 of 140
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Bristol-Myers Squibb Foundation awards nearly $1M to HBV, HCV awareness, prevention and care
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(TogoRun) The Bristol-Myers Squibb Foundation has awarded four new grants to help improve awareness, prevention and care of hepatitis B and hepatitis C in China and India. The grants total nearly $1 million and bring the Foundation's commitment to reducing hepatitis-related health disparities in Asia to $8 million over the...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 4:00:00 am
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Hepatitis - news item 112 of 140
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A Survey of Chronic Hepatitis B Patient Management Practices in the European Union
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What is the public health strategy in the European Union for treating and managing chronic hepatitis B? Journal of Viral Hepatitis (Source: Medscape Today Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 3:00:00 am
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Hepatitis - news item 113 of 140
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Genotypes and viral load of hepatitis C virus among persons attending a voluntary counseling and testing center in Ethiopia
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AbstractThe prevalence of different genotypes of hepatitis C virus (HCV) in Ethiopia is not known. HCV genotypes influence the response to therapy with alphaâ€interferon alone or in combination with ribavirin. A cross sectional study was conducted on attendees of voluntary counseling and testing center. Serum samples from 1,954 (734 HIV...
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RSS Source: Med Worm - Hepatitis Thu, 24 Feb 2011 12:24:50 am
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Hepatitis - news item 114 of 140
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A Multicenter Retrospective Study on Clinical Characteristics, Treatment Patterns, and Outcome in Elderly Patients with Hepatocellular Carcinoma.
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Conclusions. Characteristics that distinguish elderly from younger HCC patients include lower M/F ratio, worse performance status, lower rate of HCV infection, and less advanced underlying cirrhosis. Elderly patients were less likely to have a liver transplant and more likely to receive supportive care only. However, overall and HCC-specific survival were...
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 11:00:00 pm
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Hepatitis - news item 115 of 140
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Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver
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Authors: T R O'Brien, I Kohaar, R M Pfeiffer, D Maeder, M Yeager, E E Schadt & L Prokunina-Olsson (Source: Genes and Immunity)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 11:00:00 pm
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Hepatitis - news item 116 of 140
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IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-α plus ribavirin therapy in Taiwanese chronic HCV infection
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IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-α plus ribavirin therapy in Taiwanese chronic HCV infection Genes and Immunity advance online publication, February 24, 2011. doi:10.1038/gene.2011.1 Authors: J-Y Chen, C-Y Lin, C-M Wang, Y-T Lin, S-N Kuo, C-F Shiu, S-W Chang, J Wu & I-S...
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 11:00:00 pm
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Hepatitis - news item 117 of 140
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Granulocyte colonyâ€stimulating factor for hepatitis C therapyâ€associated neutropenia: systematic review and economic evaluation
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Summary.  Hepatitis C virus (HCV) treatment requires maximal adherence to pegylated interferon (Pegâ€IFN) and ribavirin to achieve a sustained virologic response (SVR). Neutropenia is the most common cause for Pegâ€IFN dose reduction. Our objectives were to evaluate the effectiveness, safety and costâ€effectiveness of granulocyte colonyâ€stimulating factor (Gâ€CSF) versus Pegâ€IFN dose...
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 11:00:00 pm
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Hepatitis - news item 118 of 140
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US federal funding for the screening and treatment of viral hepatitis is to increase to $US25 million in 2012
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(Source: PharmacoEconomics and Outcomes News)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 10:05:03 pm
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Hepatitis - news item 119 of 140
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Chromosome Remodeling Related to Hepatitis B Virus Replication in HepG2 Cells
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DNA and Cell Biology , Vol. 0, No. 0. (Source: DNA and Cell Biology)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 9:13:53 pm
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Hepatitis - news item 120 of 140
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FDA Okays Finger Stick for Hep C Test
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WASHINGTON (MedPage Today) -- The FDA has approved the use of blood obtained through a finger stick for a hepatitis C virus (HCV) test. (Source: MedPage Today Public Health)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 6:02:52 pm
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Hepatitis - news item 121 of 140
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Management of hepatitis B virus infection in the underprivileged world
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(Source: Liver International)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 4:07:30 pm
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Hepatitis - news item 122 of 140
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Cutaneous sarcoidosis developing after treatment with pegylated interferon and ribavirin: a new case and review of the literature
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We present a new case of cutaneous sarcoidosis after treatment with pegylated IFN, and a review of the literature. (Source: International Journal of Dermatology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 3:30:20 pm
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Hepatitis - news item 123 of 140
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Subgenotype and Genetic Variability in the Precore/Core Regions of Hepatitis B Virus in Korean Patients with Chronic Liver Disease
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Intervirology (DOI:10.1159/000321359) (Source: Karger Publishers)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 2:17:51 pm
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Hepatitis - news item 124 of 140
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Late diagnosed Wilson disease with hepatic and neurological manifestations
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A 50â€yearâ€old woman was referred to our hospital due to liver dysfunction and progressive neurological symptoms. She had previously been diagnosed with nonalcoholic steatohepatitis (NASH). Ursodeoxycholic acid (UDCA) had effectively normalized her serum aminotransferase levels, however, she presented with loss of balance, dysarthria and difficulty in handwriting. Autoantibodies and hepatitis...
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 10:30:08 am
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Hepatitis - news item 125 of 140
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Changes in hepatitis C viral load during first 14 days can predict the undetectable time point of serum viral load by pegylated interferon and ribavirin therapy
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Conclusion:  We created a formula for predicting the undetectable time point from viral load measurements early in PEGâ€IFNâ€Î±â€2b/ribavirin combination therapy. An early response reflects sensitivity to therapy, and the estimation of an undetectable time point would be useful for determining the optimal duration of treatment for chronic hepatitis C patients. (...
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 10:30:05 am
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Hepatitis - news item 126 of 140
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Evolution of hepatic fibrosis research
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Molecular analysis of hepatic fibrogenesis has progressed with respect to both fibrosis progression and regression by using cell biological, molecular biological and (epi)genetic approaches. Recent researches have revealed sources of collagenâ€producing cells other than hepatic stellate cells in the liver, and the involvement of the innate immune system and oxidative...
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 10:30:03 am
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Hepatitis - news item 127 of 140
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BCG reaction in a Health Worker †A Medical Error
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Exposure to blood-borne pathogens from sharp injuries continue to pose a significant risk to healthcare workers (HCW). The number of sharps injuries sustained by HCW is still unclear, primarily due to under-reporting of events. Healthcare professionals are at risk of sustaining such injuries from hollow-bore needles. Sharps injuries are associated with...
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 10:17:57 am
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Hepatitis - news item 128 of 140
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The Medical City, Lombard's Portfolio Investment, Performs First Successful Liver Transplant In The Philippines
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Lombard Investments is very proud to share the news of the first successful pediatric liver transplant surgery performed in the Philippines by an all-Filipino team at The Medical City, one of the country's premier healthcare organizations. The transplant, which entailed two simultaneous operations, took place on January 7. By January...
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 10:00:00 am
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Hepatitis - news item 129 of 140
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Vancomycin-Resistant Enterococci (VRE)
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Title: Vancomycin-Resistant Enterococci (VRE)Category: Diseases and ConditionsCreated: 5/8/2007Last Editorial Review: 2/23/2011 (Source: MedicineNet Hepatitis C General)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 6:00:00 am
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Hepatitis - news item 130 of 140
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Do You Know When NOT to Call 911?
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Title: Do You Know When NOT to Call 911?Category: Health NewsCreated: 2/23/2011 11:00:00 AMLast Editorial Review: 2/23/2011 (Source: MedicineNet Hepatitis C General)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 6:00:00 am
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Hepatitis - news item 131 of 140
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Impetigo
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Title: ImpetigoCategory: Diseases and ConditionsCreated: 12/3/1999 3:39:00 PMLast Editorial Review: 2/23/2011 (Source: MedicineNet Hepatitis C General)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 6:00:00 am
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Hepatitis - news item 132 of 140
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Clinical Features of Acute Renal Failure Associated With Hepatitis A Virus Infection
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This study takes a look. Journal of Viral Hepatitis (Source: Medscape Today Headlines)
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 3:00:00 am
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Hepatitis - news item 133 of 140
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Mass spectrometry measurement of plasma hepcidin for the prediction of iron overload
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Clinical Chemistry and Laboratory Medicine 49 (2): 197-206 Abstract Background: Hepcidin has emerged as the primary regulator of iron homeostasis. Previous studies on assessing urinary hepcidin are limited. We developed a method for quantifying hepcidin-25 (Hep-25) in plasma using surface-enhanced laser-desorption-ionization time-of-flight mass spectrometry (SELDI-TOF/MS) and a 25-AA peptide as...
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RSS Source: Med Worm - Hepatitis Wed, 23 Feb 2011 1:13:28 am
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Hepatitis - news item 134 of 140
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Development of a multiplex bead-based assay for hepatitis c diagnosis.
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DEVELOPMENT OF A MULTIPLEX BEAD-BASED ASSAY FOR HEPATITIS C DIAGNOSIS. Clin Vaccine Immunol. 2011 Feb 23; Authors: Fonseca BP, Marques CF, Nascimento LD, Mello MB, Silva LB, Rubim NM, Foti L, Silva ED, Ferreira AG, Krieger MA Hepatitis C (HCV) infection is a major burden to public health worldwide, affecting...
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RSS Source: Med Worm - Hepatitis Tue, 22 Feb 2011 11:00:00 pm
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Hepatitis - news item 135 of 140
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Fibroblast growth factorâ€2 enhances NK sensitivity of hepatocellular carcinoma cells
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In this study, we investigated the expression of FGFâ€2 in chronic hepatitis type C patients with or without HCC and the immunoregulation of FGFâ€2 in NK sensitivity of HCC cells. The FGFâ€2 expressions were detected in the liver tissues of patients, but not in normal liver. The serum FGFâ€2 levels...
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RSS Source: Med Worm - Hepatitis Tue, 22 Feb 2011 11:00:00 pm
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Hepatitis - news item 136 of 140
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Enhanced specific immune responses by CpG DNA in mice immunized with recombinant hepatitis B surface antigen and HB vaccine
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Conclusions: Our results confirmed the adjuvant effect of CpG DNA for HBsAg in the mouse model. The increase of IL10 and IL12 production suggested the involvement of Th1 cell activation. The activation of CD80 and CD86 molecules by CpG-ODN might be part of the mechanism of T /B cells coordination...
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RSS Source: Med Worm - Hepatitis Tue, 22 Feb 2011 11:00:00 pm
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Hepatitis - news item 137 of 140
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Peginterferon with or without ribavirin has minimal effect on quality of life, behavioral/emotional, and cognitive outcomes in children
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Conclusion:Overall QOL and psychosocial functioning are not deleteriously impacted by PEG 2a + RV or PL treatment of children with HCV. (HEPATOLOGY 2011.). (Source: Hepatology)
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RSS Source: Med Worm - Hepatitis Tue, 22 Feb 2011 11:00:00 pm
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Hepatitis - news item 138 of 140
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Genetic control of hepatitis A severity and susceptibility to allergy
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Hepatitis A virus (HAV) usually results in asymptomatic infection or mild disease, but in a small subset of patients it can lead to severe disease and even liver failure. In this issue of the JCI, Kim et al. identify a polymorphism associated with this increased disease risk in the gene...
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RSS Source: Med Worm - Hepatitis Tue, 22 Feb 2011 10:57:13 pm
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Hepatitis - news item 139 of 140
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A polymorphism in TIM1 is associated with susceptibility to severe hepatitis A virus infection in humans
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During infection with the hepatitis A virus (HAV), most patients develop mild or asymptomatic disease. However, a small number of patients develop serious, life-threatening hepatitis. We investigated this variability in disease severity by examining 30 Argentinean patients with HAV-induced acute liver failure in a case-control, cross-sectional, observational study. We found...
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RSS Source: Med Worm - Hepatitis Tue, 22 Feb 2011 10:57:13 pm
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Hepatitis - news item 140 of 140
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OraSure Technologies Receives FDA Approval for Its OraQuick(R) HCV Rapid Test Using Fingerstick Whole Blood
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BETHLEHEM, Pa., Feb. 22, 2011 --(HSMN NewsFeed) -- OraSure Technologies, Inc. (Nasdaq:OSUR ) announced today that its OraQuick(R) HCV Rapid Antibody Test has now been approved by the U.S. Food and Drug Administration ("FDA") for use in detecting ... Diagnostics, FDAOraSure Technologies, OraQuick, hepatitis C , HCV Rapid Antibody Test (Source: HSMN NewsFeed)
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RSS Source: Med Worm - Hepatitis Tue, 22 Feb 2011 2:03:32 pm
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