Irritable Bowel Syndrome (IBS) - news item 1 of 137
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Probiotic Helps Children with IBS
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The researchers failed to see a larger picture -- that another, much more common, far cheaper source of microbes (fermented foods) has also been shown to have big health benefits.read more (Source: Psychology Today Addiction Center)
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RSS Source: Med Worm - Irritable Bowel Symdrome Sat, 5 Mar 2011 10:39:07 pm
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Irritable Bowel Syndrome (IBS) - news item 2 of 137
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Mucosal serotonin transporter activity reduced in diarrheal IBS, celiac disease
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Patients with diarrhea-type irritable bowel syndrome or celiac disease have reduced platelet serotonin transporter function and depressed levels of serotonin transporter mRNA in the small bowel mucosa, according to results from a UK study. (Source: MedWire News - Gastroenterology)
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RSS Source: Med Worm - Irritable Bowel Symdrome Fri, 4 Mar 2011 4:18:26 pm
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Irritable Bowel Syndrome (IBS) - news item 3 of 137
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Plasma carnitine is associated with fatigue in chronic hepatitis C but not in the irritable bowel syndrome
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Conclusions  In patients with chronic hepatitis C, the severity of fatigue is associated with a low level of carnitine, suggesting that an oral supplementation may be effective to relieve fatigue in chronic hepatitis C. The underlying mechanism of fatigue in IBS does not seem to involve carnitine. (Source: Alimentary Pharmacology...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 1 Mar 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 4 of 137
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Risk factors for intestinal ischaemia among patients registered in a UK primary care database: a nested case†control study
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Conclusions  Results suggest that different risk factors are associated with acute mesenteric ischaemia and ischaemic colitis. However, due to small number of patients, associations should be carefully interpreted. (Source: Alimentary Pharmacology and Therapeutics)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 28 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 5 of 137
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[Guidelines for the Treatment of Irritable Bowel Syndrome.]
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Authors: Kwon JG, Park KS, Park JH, Park JM, Park CH, Lee KJ, Park HJ, Rhee JC, Traditional symptom-based therapies of irritable bowel syndrome (IBS) are directed at the relief of individual IBS symptoms, but they are often of limited efficacy in addressing the entire symptom complex. Combinations of drugs...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 24 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 6 of 137
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Does Exercise Improve Symptoms of IBS?
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Proven effective in the treatment of other conditions, exercise has now been shown to improve the symptoms of irritable bowel syndrome, according to a new study. Dr. David Johnson offers commentary. Medscape Gastroenterology (Source: Medscape Today Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 24 Feb 2011 2:05:48 pm
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Irritable Bowel Syndrome (IBS) - news item 7 of 137
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New laboratory tools in the assessment of bone quality
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Abstract Bone quality is a complex set of intricated and interdependent factors that influence bone strength. A number of methods have emerged to measure bone quality, taking into account the organic or the mineral phase of the bone matrix, in the laboratory. Bone quality is a complex set of different...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 24 Feb 2011 7:02:01 am
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Irritable Bowel Syndrome (IBS) - news item 8 of 137
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Distinct Neurophysiological Profiles In Irritable Bowel Syndrome.
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Conclusions: CEPs are reliable and reproducible measures of early sensory processing. Four IBS neurophysiological patterns were identified, highlighting its heterogenous nature. These findings mark the first step towards personalised medicine in IBS whereby therapy may be directed at the underlying physiological process. PMID: 21350185 [PubMed - as supplied by publisher] (...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 23 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 9 of 137
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Elevated expression of c-fos in central nervous system correlates with visceral hypersensitivity in irritable bowel syndrome (IBS): a new target for IBS treatment
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Conclusions Elevated expression of c-fos in CNS might be one of key mechanisms in etiology of IBS. Therefore, regulation of CNS activation could be a major targeting effect when treating IBS patients. Content Type Journal ArticlePages 1-10DOI 10.1007/s00384-011-1153-4Authors Ru Zhang, Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 21 Feb 2011 3:56:28 pm
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Irritable Bowel Syndrome (IBS) - news item 10 of 137
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Placebos, again | Andrew Brown
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Placebos work because people believe in them. So what do we make of a study that shows they work even when patients are told they are sugar pills?Somewhere towards the bottom of the latest God thrash, we got diverted onto the slightly different topic of placebos, and commenter meeh said...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 21 Feb 2011 8:22:00 am
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Irritable Bowel Syndrome (IBS) - news item 11 of 137
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5-HT(3) receptors: potential of individual isoforms for personalised therapy.
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Authors: Niesler B Serotonin type 3 (5-HT(3)) receptors are ligand-gated ion channels built by five subunits of diverse composition. In humans, five subunits exist (5-HT3A-E) which are encoded by the genes HTR3A-E and are expressed in various isoforms. Recently, the importance of factors influencing receptor expression became clear, such as...
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 20 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 12 of 137
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Constipation and diarrhoea - common adverse drug reactions? A cross sectional study in the general population.
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Conclusions: Use of drugs was associated with constipation and diarrhoea in the general population. The associations are most likely adverse drug reactions and show that drug-induced symptoms need to be considered in subjects with these complaints. (Source: BMC Clinical Pharmacology)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 17 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 13 of 137
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Mucosal inflammation as a potential etiological factor in irritable bowel syndrome: a systematic review
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Conclusions Low-grade mucosal inflammation, particularly mast cell activation, may be a contributory factor in the pathogenesis of IBS. Mast cell stabilizers warrant further assessment as a potential therapy in the condition. Content Type Journal ArticlePages 1-11DOI 10.1007/s00535-011-0379-9Authors Alexander C. Ford, Leeds Gastroenterology Institute, D Floor, Clarendon Wing, Leeds General Infirmary,...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 17 Feb 2011 3:59:40 pm
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Irritable Bowel Syndrome (IBS) - news item 14 of 137
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Behind the headlines: Antibiotic link to bowel problems unclear
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This study looked at the medical records of over 500,000 children in Denmark, and found that children who had been prescribed antibiotics were more likely to develop inflammatory bowel disease (IBD) than those who had not received such prescriptions. IBD is a group of diseases which includes Crohn’s disease, but...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 17 Feb 2011 3:08:43 pm
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Irritable Bowel Syndrome (IBS) - news item 15 of 137
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Microbial community and metabolomic comparison of irritable bowel syndrome faeces.
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In this study, we found no significant difference in total bacterial quantity (p>0.05). The gas chromatography-mass spectrometry (GC-MS) based multivariate analysis delineated the fecal metabolites of IBS from non-IBS samples. We found elevated levels of amino acids (alanine and pyroglutamic acid) and phenol compounds (hydroxyphenyl acetate and hydroxyphenyl propionate) in...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 16 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 16 of 137
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Effects of octreotide on jejunal hypersensitivity triggered by Cryptosporidium parvum intestinal infection in an immunocompetent suckling rat model
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Conclusions & Inferences  Data confirms the relevance of the present rat model to postinfectious IBS studies and prompt further investigation of somatostatinâ€dependent regulatory interactions in cryptosporidiosis. (Source: Neurogastroenterology and Motility)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 14 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 17 of 137
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Active protein aggregates induced by terminally attached self-assembling peptide ELK16 in Escherichia coli
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Conclusions: This has been the first report where a terminally attached self-assembling beta peptide ELK16 can promote the formation of active inclusion bodies or active protein aggregates in E. coli. It has the potential to render E. coli and other recombinant hosts more efficient as microbial cell factories for protein...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 14 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 18 of 137
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The prevalence of irritable bowel syndrome in outpatients with bulimia nervosa
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This study examined the prevalence of irritable bowel syndrome (IBS) in patients with bulimia nervosa (BN), and the relationship between these disorders.Method:Sixtyâ€four participants with a diagnosis of BN or a related condition were recruited from an outpatient eating disorders service. Questionnaire and interview measures were used to assess bulimic symptoms...
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 13 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 19 of 137
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Meta-analysis and meta-regression of hypothalamic-pituitary-adrenal axis activity in functional somatic disorders.
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In conclusion, we did not find evidence to consider all three main FSD as hypocortisolemic disorders, as significant reduction in basal cortisol compared to healthy controls was only found in CFS and in females with FM, but not in IBS. PMID: 21315796 [PubMed - as supplied by publisher] (Source: Biological...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 8 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 20 of 137
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Efficacy and safety of oral lubiprostone in constipated patients with or without irritable bowel syndrome: a randomized, placeboâ€controlled and doseâ€finding study
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Conclusions & Inferences  Our results suggest that lubiprostone produced a steady and effective improvement in the symptoms of CIC with or without IBS in a doseâ€dependent manner with a good safety profile and tolerability in a Japanese population. (Source: Neurogastroenterology and Motility)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 8 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 21 of 137
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Clinical Trials Update: Feb. 7, 2011
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Irritable Bowel Syndrome (IBS) Menstrual Migraines Shingles Vaccine (Source: The Doctors Lounge - Health News) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 7 Feb 2011 3:22:00 pm
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Irritable Bowel Syndrome (IBS) - news item 22 of 137
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Therapeutic potential of ketotifen in irritable bowel syndrome (IBS) may involve changes in mast cells at sites beyond the rectum
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(Source: Gut)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 3 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 23 of 137
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Combined oro-caecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects oro-caecal transit, not small intestinal bacterial overgrowth in patients with IBS
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Conclusions These findings demonstrate that an abnormal rise in H2 measured in the LHBT can be explained by variations in oro-caecal transit time in patients with IBS and therefore do not support the diagnosis of SIBO. (Source: Gut)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 3 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 24 of 137
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Subtypes of Irritable Bowel Syndrome Based on Abdominal Pain/Discomfort Severity and Bowel Pattern
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Conclusions Overall, the distress of IBS is more strongly related to the severity of abdominal pain/discomfort than is the predominant stool pattern in patients with IBS. Categorizing IBS patients by abdominal pain/discomfort severity in conjunction with predominant bowel pattern may be useful to clinicians and researchers in developing more effective...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 3 Feb 2011 7:53:54 pm
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Irritable Bowel Syndrome (IBS) - news item 25 of 137
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Dietary intakes in people with irritable bowel syndrome
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Conclusions: The IBS subpopulation appear to have an adequate and balanced macronutrient intake with no evidence of inadequate micronutrient intake. (Source: BioMed Central)
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 2 Feb 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 26 of 137
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IBS Relief
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Source: HealthDay - Related MedlinePlus Page: Irritable Bowel Syndrome (Source: MedlinePlus Health News) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 2 Feb 2011 1:02:02 pm
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Irritable Bowel Syndrome (IBS) - news item 27 of 137
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Methane on Breath Testing Is Associated with Constipation: A Systematic Review and Meta-analysis
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Conclusions We demonstrate that methane present on breath testing is significantly associated with constipation in both IBS and functional constipation. These results suggest there may be merit in using breath testing in constipation. Moreover, methane may be used to identify candidates for antibiotic treatment of constipation. Content Type Journal ArticlePages...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 1 Feb 2011 7:48:32 am
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Irritable Bowel Syndrome (IBS) - news item 28 of 137
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Evidence for Mast Cell Activation in Patients with Therapy-Resistant Irritable Bowel Syndrome.
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Authors: Frieling T, Meis K, Kolck UW, Homann J, Hülsdonk A, Haars U, Hertfelder HJ, Oldenburg J, Seidel H, Molderings GJ Previous findings suggested an involvement of mast cells in the pathogenesis of irritable bowel syndrome (IBS). The pathophysiological significance of mast cells is defined both by their number in...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 31 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 29 of 137
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Physical activity helps improve IBS
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Physical activity improves symptoms in patients with irritable bowel syndrome, according to Swedish researchers (Source: Nursing Times Breaking News)
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 30 Jan 2011 1:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 30 of 137
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Colonic soluble mediators from the maternal separation model of irritable bowel syndrome activate submucosal neurons via an interleukin-6-dependent mechanism
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Irritable bowel syndrome (IBS) is characterized by episodic bouts of abdominal pain, bloating, and altered bowel habit. Accumulating evidence has linked immune activation with IBS, including reports of increases in circulating levels of the proinflammatory cytokine interleukin (IL)-6. However, it is unknown whether IL-6 contributes directly to disease manifestation. As...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 27 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 31 of 137
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Cisapride for Intestinal Constipation
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Background Cisapride is a propulsive agent, withdrawn from most of the world's health institutes because of its recorded fatalities in addition to serious side effects such as severe arrhythmias. However it is widely available in third world countries and can be easily purchased through the Internet. We did a systematic...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 27 Jan 2011 2:51:32 pm
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Irritable Bowel Syndrome (IBS) - news item 32 of 137
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Symptoms In Irritable Bowel Syndrome Improved By Exercise
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The study, which was conducted at Sahlgrenska University Hospital in Gothenburg and at Alingsas Hospital, included 102 IBS patients between the ages of 18 and 65. Half the group was randomly allocated to increase their physical activity and the other half to maintain their usual lifestyle. Both groups received supportive...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 27 Jan 2011 7:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 33 of 137
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Irritable Bowel Syndrome (IBS)
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Title: Irritable Bowel Syndrome (IBS)Category: Diseases and ConditionsCreated: 2/25/2002Last Editorial Review: 1/27/2011 (Source: MedicineNet Chronic Pain General)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 27 Jan 2011 6:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 34 of 137
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Prevalence of Functional Gastrointestinal Diseases in a Cohort of Sri Lankan Adolescents: Comparison Between Rome II and Rome III Criteria
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In conclusion, FGDs were present in more than one-fourth of adolescents in the study group, of which IBS was the most common. Rome III criteria were able to diagnose FGDs more comprehensively than Rome II. (Source: Journal of Tropical Pediatrics)
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 26 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 35 of 137
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Brain Response to Rectal Distension Different in IBS
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Patients with irritable bowel syndrome experience greater brain activation in regions associated with emotional arousal and endogenous pain modulation when subjected to rectal distension, compared to controls, according to a meta-analysis published in the January issue of Gastroenterology. (Source: Modern Medicine)
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 26 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 36 of 137
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Exercise improve symptoms in irritable bowel syndrome
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Physical activity improves symptoms in patients with IBS and is protective against symptom deterioration, according to new research. (Source: ScienceDaily Headlines)
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 26 Jan 2011 3:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 37 of 137
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Exercise Improves Irritable Bowel Syndrome Symptoms
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The study, which was conducted at Sahlgrenska University Hospital in Gothenburg and at Alingsas Hospital, included 102 IBS patients between the ages of 18 and 65. (Source: Disabled World) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 25 Jan 2011 7:28:29 pm
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Irritable Bowel Syndrome (IBS) - news item 38 of 137
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Exercise improves symptoms in irritable bowel syndrome
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(University of Gothenburg) Physical activity improves symptoms in patients with IBS and is protective against symptom deterioration. This has recently been shown in a study from the University of Gothenburg, Sweden. (Source: EurekAlert! - Social and Behavioral Science)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 25 Jan 2011 4:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 39 of 137
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Factors associated with coâ€morbid irritable bowel syndrome and chronic fatigueâ€like symptoms in functional dyspepsia
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Conclusions & Inferences  ‘Somatization’ is a common risk factor for coâ€morbid IBS and CFâ€like symptoms in FD and mediates the effect of abuse. Gastric sensorimotor function and depression are specific risk factors for coâ€morbid IBS and CFâ€like symptoms, respectively. (Source: Neurogastroenterology and Motility)
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 23 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 40 of 137
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Attention to pain words in irritable bowel syndrome: Increased orienting and speeded engagement.
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Conclusions.  These results support atypical attention to pain in IBS and suggest these attentional biases are associated with increased pain report and illness behaviour. A vicious circle maintenance model of IBS, in which attentional biases exacerbate symptom perception and illness behaviour, increasing focus on pain, is a potential explanation of...
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RSS Source: Med Worm - Irritable Bowel Symdrome Fri, 21 Jan 2011 7:45:40 am
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Irritable Bowel Syndrome (IBS) - news item 41 of 137
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Identification of an Inhibitory Budding Signal that Blocks the Release of HIV Particles and Exosome/Microvesicle Proteins.
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Authors: Gan X, Gould SJ Animal cells bud exosomes and microvesicles (EMVs) from endosome and plasma membranes. The combination of higher-order oligomerization and plasma membrane-binding is a positive budding signal that targets diverse proteins into EMVs and retrovirus particles. Here we describe an inhibitory budding signal (IBS) from the HIV...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 18 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 42 of 137
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Antibiotic link to bowel problems unclear
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Conclusion Overall, this large study has suggested a link between antibiotic use and IBD, although it should not be assumed that antibiotic use is necessarily the cause of the condition. There are a number of alternative explanations for the association, such as the possibility that antibiotics had been given to...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 18 Jan 2011 4:30:00 pm
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Irritable Bowel Syndrome (IBS) - news item 43 of 137
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Antibiotics increase risk of IBS and Crohn's disease in children
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Scientists believe the drugs may encourage harmful bacteria and other organisms to grow in the gut, which trigger the conditions. (Source: the Mail online | Health)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 18 Jan 2011 8:10:57 am
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Irritable Bowel Syndrome (IBS) - news item 44 of 137
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Rifaximin (Xifaxan) for Irritable Bowel Syndrome (IBS) Treatment
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Title: Rifaximin (Xifaxan) for Irritable Bowel Syndrome (IBS) TreatmentCategory: Doctor's ViewsCreated: 1/18/2011 2:18:00 PMLast Editorial Review: 1/18/2011 2:18:56 PM (Source: MedicineNet Crohn's Disease General)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 18 Jan 2011 6:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 45 of 137
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Microporous bi-layer osmotic tablet for colon specific delivery.
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Authors: Chaudhary A, Tiwari N, Jain V, Singh R Microporous bi-layer osmotic tablet bearing dicyclomine hydrochloride and diclofenac potassium were developed using a new oral drug delivery system for colon targeting. The tablets were coated with microporous semipermeable membrane and enteric polymer using conventional pan-coating process. The developed microporous bilayer...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 17 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 46 of 137
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Relationships Among the Lactulose Breath Test, Intestinal Gas Volume, and Gastrointestinal Symptoms in Patients with Irritable Bowel Syndrome
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Conclusions Subjects with positive LBT had more gas-related symptoms and greater gas volume scores. Gas-related symptoms, positive LBT and increased GVS were significantly associated to each other. These findings can broaden the understanding of the pathophysiologic mechanisms of gas-related symptoms in IBS. Content Type Journal ArticlePages 1-8DOI 10.1007/s10620-011-1569-2Authors Young Hoon...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 17 Jan 2011 7:30:07 pm
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Irritable Bowel Syndrome (IBS) - news item 47 of 137
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A Promising New Treatment Option for IBS
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Dr. David Johnson comments on a recent study that found the antibiotic rifaximin to be an effective treatment for patients with irritable bowel syndrome. How will it affect clinical practice? Medscape Gastroenterology (Source: Medscape Pharmacist Headlines)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 11 Jan 2011 2:10:16 pm
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Irritable Bowel Syndrome (IBS) - news item 48 of 137
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Antibiotic Prophylaxis Prevents the Development of a Post-Infectious Phenotype in a New Rat Model of Post-Infectious IBS
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Conclusions Prophylactic treatment of rats with the antibiotic rifaximin in a new animal model of post-infectious IBS with C. jejuni mitigated the development of long-term altered stool form and function. Content Type Journal ArticlePages 1-5DOI 10.1007/s10620-010-1548-zAuthors Mark Pimentel, GI Motility Program, Division of Gastroenterology, Cedars-Sinai Medical Center, 8730 Alden Drive,...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 10 Jan 2011 7:06:42 pm
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Irritable Bowel Syndrome (IBS) - news item 49 of 137
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Research Led By Cedars-Sinai Shows Antibiotic Treatment Effective For Patients With IBS.
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A ground-breaking antibiotic therapy developed at Cedars-Sinai Medical Center is the first potential drug treatment to provide irritable bowel syndrome patients with long-lasting relief of their symptoms even after they stop taking the medication, according to a study published in the Jan. 6 issue of the New England Journal of...
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RSS Source: Med Worm - Irritable Bowel Symdrome Fri, 7 Jan 2011 7:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 50 of 137
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Calming Irritable Bowel Syndrome with an antibiotic
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Affecting up to one in five Americans, irritable bowel syndrome (IBS) is a common gastrointestinal ailment that may cause abdominal pain, bloating, diarrhea and constipation, particularly in women. (Source: Health Facts and Fears) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest,...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 51 of 137
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Antibiotic Rifaximin Extremely Effective In Irritable Bowel Syndrome Treatment
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Rifaximin, a minimally absorbed antibiotic that stays in the gut has been found to provide long-lasting relief for patients with irritable bowel syndrome (IBS), researchers have revealed in NEJM (New England Journal of Medicine). IBS patients experienced relief long after they had stopped taking the drug. The authors report that...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 52 of 137
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Antiobotic shown effective for IBS
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LOS ANGELES, Jan. 6 (UPI) -- A two-week course of antibiotics can reduce symptoms in many patients with irritable bowel syndrome for at least 10 weeks or even longer, U.S. researchers say. (Source: Health News - UPI.com)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 8:00:40 pm
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Irritable Bowel Syndrome (IBS) - news item 53 of 137
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Antibiotic eases IBS pain, study finds
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Some people suffering from irritable bowel syndrome can benefit from a two-week course of antibiotics, a study has shown (Source: Nursing in Practice)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 8:00:35 pm
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Irritable Bowel Syndrome (IBS) - news item 54 of 137
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Antibiotic Passes Test for Use in IBS (CME/CE)
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(MedPage Today) -- Patients with nonconstipation irritable bowel syndrome had significant improvement in symptoms following two weeks of treatment with the antibiotic rifaximin (Xifaxan), results of two randomized trials showed. (Source: MedPage Today Gastroenterology)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 4:13:02 pm
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Irritable Bowel Syndrome (IBS) - news item 55 of 137
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Antibiotic helps IBS bowel disorder symptoms in some
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Two weeks of treatment with an already well-known antibiotic appears to offer relief to those suffering from at least one type of irritable bowl syndrome, new research finds. (Source: CTV Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 3:37:49 pm
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Irritable Bowel Syndrome (IBS) - news item 56 of 137
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Antibiotic used to treat travellers' stomach bugs could help ease pain of IBS
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A U.S. study has shown for the first time that the condition - which causes abdominal discomfort - could be relieved by administering antibiotics. (Source: the Mail online | Health)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 10:22:52 am
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Irritable Bowel Syndrome (IBS) - news item 57 of 137
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Health Headlines: Flu, IBS and Asthma
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Welcome to our daily round-up of health stories making the national news. Don't forget to tell us your views. (Source: HealthcareRepublic Pharmacist News)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 9:18:00 am
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Irritable Bowel Syndrome (IBS) - news item 58 of 137
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Antibiotic Therapy Relieves IBS
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2 Weeks of Antibiotic Therapy Relieves IBS (Source: eMedicineHealth.com) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 6:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 59 of 137
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2 Weeks of Antibiotic Therapy Relieves IBS
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Title: 2 Weeks of Antibiotic Therapy Relieves IBSCategory: Health NewsCreated: 1/6/2011 11:00:00 AMLast Editorial Review: 1/6/2011 (Source: MedicineNet Crohn's Disease General)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 6 Jan 2011 6:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 60 of 137
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Rifaximin improves symptoms in some patients with irritable bowel syndrome
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Source: N Engl J Med Area: News Treatment with rifaximin improves symptoms of irritable bowel disease (IBS) without constipation, according to a pair of linked controlled trials published in the NEJM today. IBS is common, but there are few treatments of proven efficacy. There is evidence that IBS patients may...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 5 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 61 of 137
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Antibiotic Passes Test for Use in IBS (CME/CE, with video)
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(MedPage Today) -- Patients with nonconstipation irritable bowel syndrome had significant improvement in symptoms following two weeks of treatment with the antibiotic rifaximin (Xifaxan), results of two randomized trials showed. (Source: MedPage Today Gastroenterology)
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 5 Jan 2011 9:43:52 pm
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Irritable Bowel Syndrome (IBS) - news item 62 of 137
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Antibiotic may ease IBS
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An antibiotic widely used to treat diarrhea in travelers may also provide some relief to people with the common and difficult-to-treat condition known as irritable bowel syndrome, according to a pair of new studies in the New England Journal of Medicine. (Source: CNN.com - Health)
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 5 Jan 2011 9:11:25 pm
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Irritable Bowel Syndrome (IBS) - news item 63 of 137
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Review article: the functional abdominal pain syndrome
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Conclusion  Although few studies have assessed functional abdominal pain syndrome or its treatment specifically, the treatment strategies outlined in this paper appear to be effective. (Source: Alimentary Pharmacology and Therapeutics)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 3 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 64 of 137
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The Association between Irritable Bowel Syndrome and the Anxiety Vulnerability Factors: Body Vigilance and Discomfort Intolerance
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Individuals with Irritable Bowel Syndrome (IBS) endorse greater negative affect, including anxiety psychopathology. To examine the role anxiety plays in the maintenance and exacerbation of IBS the links between IBS and two anxiety related constructs, body vigilance and discomfort intolerance, were examined. A non-treatment seeking college sample (N = 476) completed...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 3 Jan 2011 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 65 of 137
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Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome.
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Authors: Manning DD, Cioffi CL, Usyatinsky A, Fitzpatrick K, Masih L, Guo C, Zhang Z, Choo SH, Sikkander MI, Ryan KN, Naginskaya J, Hassler C, Dobritsa S, Wierschke JD, Earley WG, Butler AS, Brady CA, Barnes NM, Cohen ML, Guzzo PR Serotonin type 3 (5-HT(3)) receptor partial agonists are being...
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RSS Source: Med Worm - Irritable Bowel Symdrome Fri, 31 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 66 of 137
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Modulation of visceral hypersensitivity by glial cell line-derived neurotrophic factor (GDNF) family receptor alpha-3 in colorectal afferents.
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Authors: Tanaka T, Shinoda M, Feng B, Albers KM, Gebhart GF Irritable bowel syndrome (IBS) is characterized by colorectal hypersensitivity and contributed to by sensitized mechanosensitive primary afferents and recruitment of mechano-insensitive (silent) afferents. Neurotrophic factors are well known to orchestrate dynamic changes in the properties of sensory neurons. Although...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 29 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 67 of 137
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Kiwifruit improves bowel function in patients with irritable bowel syndrome with constipation.
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Authors: Chang CC, Lin YT, Lu YT, Liu YS, Liu JF Irritable bowel syndrome (IBS) is a common functional disorder of the gastrointestinal system, and is characterized by abdominal pain, diarrhea (IBS/D), constipation (IBS/C), and alternating diarrhea and constipation (IBSC/A). The purpose of this study was to examine the impact...
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 26 Dec 2010 5:10:04 am
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Irritable Bowel Syndrome (IBS) - news item 68 of 137
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IBS Patients Cite Benefits After Knowingly Taking Dummy Pill
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IBS patients cite benefits after knowingly taking a placebo. WebMD Health News (Source: Medscape Today Headlines)
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 23 Dec 2010 3:59:06 pm
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Irritable Bowel Syndrome (IBS) - news item 69 of 137
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Placebos Without Deception Still Work in IBS
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The placebo effect appears to work in some irritable bowel syndrome patients even when they know their treatment contains nothing more than an inert substance, according to research published online Dec. 22 in PLoS ONE. (Source: Modern Medicine)
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 22 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 70 of 137
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In the News: The Placebo Effect
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The placebo effect is a beneficial health outcome resulting from a person's anticipation that an intervention—pill, procedure, or injection, for example—will help them. A clinician's style in interacting with patients also may bring about a positive response that is independent of any specific treatment.According to a recent study published in...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 22 Dec 2010 9:17:52 pm
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Irritable Bowel Syndrome (IBS) - news item 71 of 137
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Placebo effect works even if patients know they're getting a sham drug
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Study suggests patients benefit from the placebo effect even when told explicitly that they're taking an 'inert substance'Ben Goldacre: Can a placebo have side-effects?Patients can benefit from being treated with sham drugs even if they are told they contain no active ingredient, scientists have found. The finding suggests that the...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 22 Dec 2010 8:59:01 pm
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Irritable Bowel Syndrome (IBS) - news item 72 of 137
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Lubiprostone Reverses the Inhibitory Action of Morphine on Mucosal Secretion in Human Small Intestine
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Conclusions Antisecretory action of morphine results from suppression of excitability of secretomotor neurons in the enteric nervous system. Lubiprostone, which does not affect enteric neurons directly, bypasses the action of morphine by directly opening mucosal chloride channels. Content Type Journal ArticleDOI 10.1007/s10620-010-1515-8Authors Xiaohong Sun, Department of Physiology and Cell Biology,...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 22 Dec 2010 7:19:40 pm
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Irritable Bowel Syndrome (IBS) - news item 73 of 137
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Neural Autoantibody Evaluation in Functional Gastrointestinal Disorders: A Population-Based Case†Control Study
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Conclusions Our data do not support neural autoimmunity as the basis for most IBS or functional dyspepsia cases. Content Type Journal ArticleDOI 10.1007/s10620-010-1514-9Authors Sean J. Pittock, Division of Multiple Sclerosis and Autoimmune Neurology, Department of Neurology, Mayo Clinic, 200 First Street S.W., Rochester, MN 55905, USAVanda A. Lennon, Division of...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 22 Dec 2010 7:19:35 pm
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Irritable Bowel Syndrome (IBS) - news item 74 of 137
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Reply
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We are grateful to Drs Wang and Chang for their thoughtful review of our study of the 8-year prognosis of postinfectious irritable bowel syndrome (IBS) in the Walkerton Health Study cohort. The outbreak of acute gastroenteritis in this community in 2000 was a public health tragedy, but has provided valuable...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 21 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 75 of 137
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How Fiber Helps Digestive Health
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Fiber aids digestive health and helps prevent GERD, inflammatory bowel syndrome (IBS), obesity, and diverticulitis. (Source: WebMD Health)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 21 Dec 2010 4:07:58 pm
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Irritable Bowel Syndrome (IBS) - news item 76 of 137
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Surprising Information About Placebos
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A placebo is a pill or other treatment that has no real effect. Once called "sugar pills," doctors would give them to patients because even though they contained no medication, they often worked. Today placebos are commonly used in clinical trials to test the effectiveness and sometimes side effectiveness of...
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 19 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 77 of 137
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Text messaging: an innovative way of data collection in medical research
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Conclusions: This study found using text messaging via mobile phone an excellent instrument for collecting weekly symptom reports in response to trial medication, reminding trial subjects to attend face to face visits and completing more complex paper based evaluation. The 100% response rate of weekly symptom reports was facilitated by...
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 19 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 78 of 137
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Keratin gene mutations in disorders of human skin and its appendages.
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Authors: Chamcheu JC, Siddiqui IA, Syed DN, Adhami VM, Liovic M, Mukhtar H Keratins, the major structural protein of all epithelia, are a diverse group of cytoskeletal scaffolding proteins that form intermediate filament networks, providing structural support to keratinocytes that maintain the integrity of the skin. Expression of keratin genes...
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RSS Source: Med Worm - Irritable Bowel Symdrome Sat, 18 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 79 of 137
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For Treatment Of Irritable Bowel Syndrome, Linaclotide Will Emerge As The Market Leader And Will Achieve Blockbuster Status In 2019
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Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, owing to its superb efficacy, acceptable safety profile and anticipated launch in all major markets, Ironwood/Forest/Almirall/Astellas's linaclotide will emerge as the market leader for the treatment of irritable bowel syndrome (IBS). In...
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RSS Source: Med Worm - Irritable Bowel Symdrome Fri, 17 Dec 2010 11:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 80 of 137
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Colonic hypersensitivity is a major determinant of the efficacy of bloating treatment in constipation-predominant irritable bowel syndrome
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Abstract The pathophysiology of bloating is largely unknown, and many mechanisms have been proposed. An alteration of intestinal gas production may have a role in a subgroup of patients, but available data are conflicting. We have previously shown that hypersensitivity to colonic fermentation is associated with severe bloating in a...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 16 Dec 2010 5:54:56 am
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Irritable Bowel Syndrome (IBS) - news item 81 of 137
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Altered Purinergic Signaling in Colorectal Dorsal Root Ganglion Neurons Contributes to Colorectal Hypersensitivity
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Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by pain and hypersensitivity in the relative absence of colon inflammation or structural changes. To assess the role of P2X receptors expressed in colorectal dorsal root ganglion (c-DRG) neurons and colon hypersensitivity, we studied excitability and purinergic signaling of retrogradely...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 14 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 82 of 137
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LXâ€1031, a tryptophan 5â€hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin
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Abstract  LXâ€1031 is an oral, small molecule tryptophan 5â€hydroxylase (TPH) inhibitor that reduces serotonin (5â€HT) synthesis peripherally. It has potential for illnesses characterized by excess 5â€HT, such as diarrheaâ€predominant irritable bowel syndrome (IBSâ€D) and carcinoid diarrhea. In vitro, inhibition of TPH1 occurred in 10âˆ'8†10âˆ'7 mol Lâˆ'1 range. In vivo in rodents,...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 14 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 83 of 137
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Clinical Trials Update: Dec. 13, 2010
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Overactive Bladder (OAB) IBS-D Osteoarthritis of the Knee (Source: The Doctors Lounge - Health News)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 13 Dec 2010 6:08:00 pm
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Irritable Bowel Syndrome (IBS) - news item 84 of 137
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Effects of the N-Methyl-D-Aspartate Receptor on Temporal Summation of Second Pain (Wind-up) in Irritable Bowel Syndrome
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This study evaluates temporal summation of second pain in a subset of IBS patients that is blocked by Dextromethorphan, an NMDA receptor antagonist. Theses results could lead to the use of an NMDA receptor antagonist in the treatment of pain in a subset of IBS patients. (Source: The Journal of...
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 12 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 85 of 137
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Increased fatigability of external anal sphincter in inflammatory bowel disease
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I read with a great interest the recent article by Papathanasopoulos AA et al. The article has very important outcomes related with pathophysiology of fecal incontinence (FI) in inflammatory bowel disease (IBD) patients. But, there are some items to be clarified. First issue of my concern is related with the...
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 12 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 86 of 137
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In IBS, A Patient's Response To Hypnotherapy Can Be Predicted By Color Test
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When people with irritable bowel syndrome (IBS) were asked to relate their mood to a color, those choosing a positive color were nine times more likely to respond to hypnotherapy than those who chose a negative color or no color at all. Researchers writing in the open access journal BMC...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 8 Dec 2010 8:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 87 of 137
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The interpretation of Rome III criteria and method of assessment affect the irritable bowel syndrome classification of children
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Conclusions  Poor congruence among methods suggests that Rome III IBS criteria need better specification, and efforts to improve parentâ€child agreement are necessary. (Source: Alimentary Pharmacology and Therapeutics) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 7 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 88 of 137
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Mood color choice helps to predict response to hypnotherapy in patients with irritable bowel syndrome
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Background: Approximately two thirds of patients with irritable bowel syndrome (IBS) respond well to hypnotherapy. However, it is time consuming as well as expensive to provide and therefore a way of predicting outcome would be extremely useful. The use of imagery and color form an integral part of the hypnotherapeutic...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 6 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 89 of 137
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Dandelion juice may soothe eczema, antibiotics could treat IBS and jelly could ease creaky knees
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Researchers point to anecdotal reports over the years that the dandelion juice has benefits in the treatment of dyshidrotic eczema. (Source: the Mail online | Health)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 6 Dec 2010 10:13:17 pm
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Irritable Bowel Syndrome (IBS) - news item 90 of 137
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Toll-like receptors may point to immune changes in IBS
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Individuals with irritable bowel syndrome have alterations in levels of toll-like receptors that suggest the innate immune system plays a role in the pathogenesis of the syndrome, conclude investigators. (Source: MedWire News - Gastroenterology)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 6 Dec 2010 3:18:51 pm
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Irritable Bowel Syndrome (IBS) - news item 91 of 137
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Implications of Melatonin Therapy in Irritable Bowel Syndrome; A systematic Review.
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In conclusion melatonin can be a target of interest in IBS because of its potentials to regulate GI motility. PMID: 21128901 [PubMed - as supplied by publisher] (Source: Current Pharmaceutical Design) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 2 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 92 of 137
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Current Developments for the Diagnosis and Treatment of Irritable Bowel Syndrome.
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Authors: Grundmann O, Yoon SL, Moshiree B Current treatment options for the chronic gastrointestinal disorder irritable bowel syndrome (IBS) have long been limited to symptomatic treatments due to lack of pathophysiologic understanding of the syndrome. Within the past 10 years, however, a number of new pharmacological targets have been identified...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 2 Dec 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 93 of 137
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Are GPS Missing A Trick When It Comes To Lactose Intolerance?
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A new survey, commissioned by Lactofree, has identified a potential 'quick win' in terms of dealing with patients complaining of recurrent bouts of bloating, wind, nausea, diarrhoea and stomach cramps. Three quarters of GPs (76 per cent) faced with such symptoms would diagnose IBS1, however it is estimated that up...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 2 Dec 2010 10:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 94 of 137
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Endoscopic and symptoms analysis in Mexican patients with irritable Bowel syndrome, dyspepsia, and gastroesophageal reflux disease.
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In conclusion, nearly half of the Mexican patients with NERD, EE and dyspepsia fulfill criteria for IBS. A large number of symptoms were correlated with endoscopy, which can be used to improve the indication of the endoscopy and its implementation in clinical studies. PMID: 21152770 [PubMed - in process] (Source:...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 30 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 95 of 137
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Serotonin Synthesis Inhibitor Improves IBS Symptoms
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Major Finding: LX1031 is a novel, orally administered serotonin synthesis inhibitor that produced a statistically significant improvement in IBS symptoms over a 4-week period in patients with nonconstipating IBS. There was a significant correlation between percent reduction in urinary 5-HIAA and global response, with the best responders to high-dose LX1031...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 30 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 96 of 137
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Linaclotide Effective for IBS With Constipation
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Linaclotide was associated with significant improvement in symptoms of irritable bowel syndrome with constipation, including abdominal pain, within 1 week of therapy, Dr. Jeffrey M. Johnston and colleagues reported in Gastroenterology. (Source: Family Practice News)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 30 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 97 of 137
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Pathogenic Factors Involved in the Development of Irritable Bowel Syndrome: Focus on a Microbial Role
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Irritable bowel syndrome (IBS) is a symptom complex characterized by recurrent abdominal pain or discomfort, and accompanied by abnormal bowel habits, in the absence of any discernible organic abnormality. Its origin remains unclear, partly because multiple pathophysiologic mechanisms are likely to be involved. A significant proportion of patients develop IBS...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 30 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 98 of 137
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PhyloChip microarray analysis reveals altered gastrointestinal microbial communities in a rat model of colonic hypersensitivity
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Conclusions & Inferences  The PhyloChip is a useful and convenient method to study enteric microflora. Further, this rat model system may be a useful experimental platform to study the causes and consequences of changes in microbial community composition associated with IBS. (Source: Neurogastroenterology and Motility)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 30 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 99 of 137
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Mechanisms underlying gut dysfunction in a murine model of chronic parasitic infection
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Irritable bowel syndrome (IBS) is common in countries where chronic parasitic infestations are endemic. However, the relationship between parasitic infection and IBS is not clear. The aim of this study was to examine whether chronic parasitic infection is accompanied by gut dysfunction and whether the continued presence of the parasite...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 30 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 100 of 137
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Differences between risk factors among irritable bowel syndrome subtypes in Japanese adults
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Conclusions & Inferences  Irritable bowel syndrome was common and associated with young age, female gender, low BMI, and presence of allergic diseases in Japanese adults. Several differences were noted between the risk factors among different IBS subtypes. (Source: Neurogastroenterology and Motility)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 30 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 101 of 137
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A Randomized Controlled Trial of Lactobacillus GG in Children With Functional Abdominal Pain
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CONCLUSIONS: LGG significantly reduces the frequency and severity of abdominal pain in children with IBS; this effect is sustained and may be secondary to improvement of the gut barrier. (Source: PEDIATRICS)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 30 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 102 of 137
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Pooled analysis of brain activity in irritable bowel syndrome and controls during rectal balloon distension
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Conclusions & Inferences  Our pooled analysis demonstrates that the literature reports are quite heterogeneous but there is some evidence that there may be patterns of higher activity more common in individuals with IBS than in controls. A consensus, though, regarding study designs, analysis approach and reporting could create a clearer...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 30 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 103 of 137
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Clinical Trials Update: Nov. 29, 2010
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High Cholesterol Excessive Urination Irritable Bowel Syndrome (IBS) (Source: The Doctors Lounge - Health News)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 29 Nov 2010 6:44:00 pm
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Irritable Bowel Syndrome (IBS) - news item 104 of 137
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Glucagon-like Peptide-1 gastrointestinal regulatory role in metabolism and motility.
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Authors: Hellström PM Gastrointestinal (GI) motility, primarily gastric emptying, balances the hormonal output that takes place after food intake in order to maintain stable blood sugar. The incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), work together to reduce postprandial hyperglycemia by glucose-dependent insulin secretion and inhibition of...
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RSS Source: Med Worm - Irritable Bowel Symdrome Sat, 27 Nov 2010 8:05:03 pm
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Irritable Bowel Syndrome (IBS) - news item 105 of 137
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Abdominal Pain Beyond IBS
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Question: A 26-year-old woman presented with abdominal pain, nausea, and vomiting. Her history revealed episodes of abdominal pain over the past 5 years, and bloating and diarrhea lasting approximately 2 days without an obvious nutritional precipitant. She had been classified as having irritable bowel syndrome, because previous investigations including endoscopy (...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 24 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 106 of 137
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Breaking Down Bowel Barriers
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Last month, all of the health guides on about.com were challenged by the guide to Irritable Bowel Syndrome (http://ibs.about.com). The goal was to get readers talking about the unmentionables- bowel ...Read Full Post (Source: About.com Lymphoma)
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 21 Nov 2010 10:18:34 pm
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Irritable Bowel Syndrome (IBS) - news item 107 of 137
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Abdominal Pain in Irritable Bowel Syndrome: A Review of Putative Psychological, Neural and Neuro-Immune Mechanisms.
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Authors: Elsenbruch S Chronic abdominal pain is a common symptom of great clinical significance in several areas of medicine. In many cases no organic cause can be established resulting in the classification as functional gastrointestinal disorder. Irritable Bowel Syndrome (IBS) is the most common of these conditions and is considered...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 18 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 108 of 137
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Management of Irritable Bowel Syndrome in Primary Care: Feasibility Randomised Controlled Trial of mebeverine, methylcellulose, placebo and a patient self-management cognitive behavioural therapy website. (MIBS Trial).
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DiscussionThis pilot will provide valuable information for a larger trial. Determining the effectiveness of commonly used drug treatments will help patients and doctors make informed treatment decisions regarding drug management of IBS symptoms, enabling better targeting of treatment. A web-based self-management CBT programme for IBS developed in partnership with patients...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 17 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 109 of 137
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Lactobacillus GG May Help Treat Abdominal Pain in Children With IBS
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Lactobacillus rhamnosus strain GG reduces the frequency and severity of abdominal pain in children with irritable bowel syndrome, with persistent benefit once treatment is stopped. Medscape Medical News (Source: Medscape Today Headlines)
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 17 Nov 2010 8:49:22 pm
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Irritable Bowel Syndrome (IBS) - news item 110 of 137
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Stability of the Irritable Bowel Syndrome and Subgroups as Measured by Three Diagnostic Criteria -- A 10-year Follow-up Study
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What are the diagnostic criteria for determining the degree of illness in IBS? Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 16 Nov 2010 11:38:47 am
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Irritable Bowel Syndrome (IBS) - news item 111 of 137
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Hypnotherapy for children with functional abdominal pain or irritable bowel syndrome: Long term follow-up
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Objectives: Functional abdominal pain (FAP) and irritable bowel syndrome (IBS) in childhood are among the most common reasons for consultation in paediatrics with reported prevalence of 1†19%. Treatment usually consists of education, reassurance and dietary advices. Nevertheless, a significant proportion continues to experience symptoms and for long, efficient therapies...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 16 Nov 2010 4:37:54 am
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Irritable Bowel Syndrome (IBS) - news item 112 of 137
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Probiotic Helps Children's Stomach Pain
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A common probiotic may help ease tummy troubles for children with chronic stomach pain caused by irritable bowel syndrome (IBS). (Source: WebMD Health)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 16 Nov 2010 3:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 113 of 137
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Lactobacillus GG Linked to Benefits in Childhood IBS
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Lactobacillus rhamnosus GG may reduce abdominal pain in children with irritable bowel syndrome, possibly due to improvement of the gut barrier, according to research published online Nov. 15 in Pediatrics. (Source: Modern Medicine)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 15 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 114 of 137
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Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome
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Conclusions & Inferences  This study is the first to assess associations of TPH gene variants with IBSâ€related GI symptoms and stool characteristics. The possible association of TPH gene variants with diarrhea needs to be verified in an independent sample. (Source: Neurogastroenterology and Motility)
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RSS Source: Med Worm - Irritable Bowel Symdrome Sat, 13 Nov 2010 3:42:22 am
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Irritable Bowel Syndrome (IBS) - news item 115 of 137
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Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota
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Conclusion: Molecular profiling of faecal bacteria revealed abnormalities of intestinal microbiota in UC and IBS patients, while different patterns of Bacteroides species loss in particular, were associated with UC and IBS. (Source: BMC Gastroenterology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 11 Nov 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 116 of 137
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Prospective Diary Evaluation of Unexplained Abdominal Pain and Bowel Dysfunction: A Population-Based Colonoscopy Study
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Conclusions Current criteria for IBS that rely on recall of the relationship between abdominal pain and bowel disturbance may overcall this association when measured prospectively. Content Type Journal ArticleDOI 10.1007/s10620-010-1468-yAuthors Susanna A. Walter, Institution of Clinical and Experimental Medicine (IKE), Division of Gastroenterology, Linköping University, Linköping, SwedenLars Kjellström, Department of...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 10 Nov 2010 9:53:18 am
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Irritable Bowel Syndrome (IBS) - news item 117 of 137
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Ironwood And Forest Announce Positive Linaclotide Results From Second Phase 3 Trial In Patients With Irritable Bowel Syndrome With Constipation
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Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) and Forest Laboratories, Inc. (NYSE: FRX) today announced positive top-line results from a 26-week Phase 3 clinical trial assessing the efficacy and safety of the investigational drug linaclotide in patients with irritable bowel syndrome with constipation (IBS-C). (Source: Pharmaceutical Online News)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 1 Nov 2010 7:30:00 pm
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Irritable Bowel Syndrome (IBS) - news item 118 of 137
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Efficacy of IBS Drug Reflects Gene Variation: Screening for common polymorphisms may help predict patients' response to chenodeoxycholate.
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Major Finding: In women with constipation-predominant IBS (IBS-C), genetic variations in bile acid regulatory genes may determine the therapeutic response to the drug sodium chenodeoxycholate. (Source: Family Practice News)
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 31 Oct 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 119 of 137
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This Month in Gastroenterology
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Irritable bowel syndrome (IBS) is probably the most common condition that gastroenterologists see in clinical practice. Based on the Rome consensus recommendations, IBS is subcategorized based on bowel patterns into IBS with constipation (IBS-C), IBS with diarrhea, and mixed or alternating IBS. The number of available and effective treatments for...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 27 Oct 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 120 of 137
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Serum S100A12 helps distinguish IBD from IBS patients
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The calcium binding, pro-inflammatory protein S100A12 is present at higher levels in patients with inflammatory bowel disease than in those with irritable bowel syndrome, say researchers who believe it may serve as an inflammatory marker. (Source: MedWire News - Gastroenterology) MedWorm Message: Watch the new MedWorm demo and find out...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 26 Oct 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 121 of 137
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[Usefulness of Lactulose Breath Test for the Prediction of Small Intestinal Bacterial Overgrowth in Irritable Bowel Syndrome.]
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Conclusions: LBT was not useful to discriminate IBS/FBD patients from the control. The assessment of SIBO by LBT in IBS should be revalidated in the future. PMID: 20962560 [PubMed - as supplied by publisher] (Source: Korean J Gastroenter...)
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RSS Source: Med Worm - Irritable Bowel Symdrome Sun, 24 Oct 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 122 of 137
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Preparation and Reactivity of Polystyrene-Supported Iodosylbenzene Sulfate: An Efficient Recyclable Oxidizing System
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SynlettDOI: 10.1055/s-0030-1259011AbstractA new polymer-supported hypervalent iodine reagent, polystyrene-supported iodosylbenzene sulfate (PS-IBS), can be conveniently prepared by the reaction of polystyrene-supported (diacetoxyiodo)benzene (PS-DIB) with sodium bisulfate monohydrate under solvent-free conditions. This new recyclable reagent effects clean and efficient oxidation of a wide range of alcohols and sulfides to the corresponding carbonyl...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 21 Oct 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 123 of 137
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New Book From The AGA Helps Patients Achieve Greater Freedom From IBS
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A new book from the American Gastroenterological Association (AGA) offers patients with irritable bowel syndrome (IBS) a variety of strategies to lessen the burden that IBS puts on their everyday lives. IBS is a common disorder of the intestines that leads to crampy pain, gassiness, bloating and changes in bowel...
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RSS Source: Med Worm - Irritable Bowel Symdrome Fri, 15 Oct 2010 7:00:00 am
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Irritable Bowel Syndrome (IBS) - news item 124 of 137
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Molecular analysis of faecal and duodenal samples reveals significantly higher prevalence and numbers of Pseudomonas aeruginosa in IBS.
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This study shows that P. aeruginosa is detected more frequently and in higher levels in IBS patients than in HS suggesting its potential role in the pathophysiology of IBS. PMID: 20947663 [PubMed - as supplied by publisher] (Source: Journal of Medical Microbiology) MedWorm Message: Watch the new MedWorm demo and...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 13 Oct 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 125 of 137
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Moderate performance of serum S100A12, in distinguishing inflammatory bowel disease from irritable bowel syndrome
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In this study, the utility of serum S100A12, in discriminating IBD from irritable bowel syndrome (IBS), was tested. Methods: S100A12 serum levels were determined in 64 patients with ulcerative colitis (UC), 64 with Crohn's disease (CD) and 73 with IBS, by means of an enzyme-linked immunosorbent assay. S100A12 serum levels...
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RSS Source: Med Worm - Irritable Bowel Symdrome Wed, 13 Oct 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 126 of 137
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Melatonin, a Potential Therapeutic Agent for Smooth Muscle-Related Pathological Conditions and Aging.
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In conclusion, melatonin may be a promising candidate for future research of agents that modulate smooth muscle motility. PMID: 20939818 [PubMed - as supplied by publisher] (Source: Current Medicinal Chemistry)
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 12 Oct 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 127 of 137
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Parasites in Mexican patients with irritable bowel syndrome: a case-control study
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One hundred and fifteen patients with symptoms suggestive of irritable bowel syndrome (IBS) according to Rome III criteria and two hundred and nine patients with gastrointestinal symptoms different from IBS (control) were identified through medical records from the Gastroenterology Clinic of the "Dr. Manuel Gea Gonzalez General Hospital" from January...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 12 Oct 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 128 of 137
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Gut inflammation in chronic fatigue syndrome
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Chronic fatigue syndrome (CFS) is a debilitating disease characterized by unexplained disabling fatigue and a combination of accompanying symptoms the pathology of which is incompletely understood. Many CFS patients complain of gut dysfunction. In fact, patients with CFS are more likely to report a previous diagnosis of irritable bowel syndrome (...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 11 Oct 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 129 of 137
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Gut Check: Test Your Gastro Knowledge
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Test your knowledge of a range of common GI complaints. Duke gastroenterologist Rahul Shimpi, MD, helps digest the information. 1. True or false? Diet plays an important role in gastrointestinal complaints. Often true -- but not always. “though I’m not convinced there’s a dietary link with all things digestive,†says...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 5 Oct 2010 4:23:57 am
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Irritable Bowel Syndrome (IBS) - news item 130 of 137
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Maternal separation as a model of brain†gut axis dysfunction
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Conclusion Thus, maternally separated animals are an excellent model of brain†gut axis dysfunction for the study of disorders such as IBS and for the development of novel therapeutic interventions. Content Type Journal ArticleDOI 10.1007/s00213-010-2010-9Authors Siobhain M. O’Mahony, Alimentary Pharmabiotic Centre, Biosciences Institute, University College Cork, Cork, IrelandNiall P. Hyland,...
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RSS Source: Med Worm - Irritable Bowel Symdrome Fri, 1 Oct 2010 6:11:25 am
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Irritable Bowel Syndrome (IBS) - news item 131 of 137
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Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome
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Abstract: Irregularities of serotonin function in irritable bowel syndrome (IBS) may be due to changes in the metabolism of the serotonin precursor l-tryptophan. Dietary alteration of tryptophan intake may impact upon the mood and bowel symptoms of IBS. We hypothesized that diarrhea-predominant irritable bowel syndrome (d-IBS) patients would exhibit an...
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RSS Source: Med Worm - Irritable Bowel Symdrome Thu, 30 Sep 2010 11:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 132 of 137
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Reconciling the analysis of IBD and IBS in complex trait studies
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Authors: Joseph E. Powell, Peter M. Visscher & Michael E. Goddard Identity by descent (IBD) is a fundamental concept in genetics and refers to alleles that are descended from a common ancestor in a base population. Identity by state (IBS) simply refers to alleles that are the same, irrespective of...
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 27 Sep 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 133 of 137
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Increased accumulation of intron-containing transcripts in rice mitochondria caused by low temperature: is cold-sensitive RNA editing implicated?
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Authors: Kurihara-Yonemoto S, Kubo T An increase in the unspliced cox2 transcript and accompanying decrease in the frequency of RNA editing near the exon/intron junction (intron binding site 1, IBS1) have been reported in cold-treated wheat. Here, an attempt was made to clarify whether a similar phenomenon occurs in rice....
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 27 Sep 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 134 of 137
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Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome.
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CONCLUSION: Bacteria seemingly affecting the symptom scores are unlikely to be the underlying cause or cure of IBS, but they may serve as biomarkers of the condition. PMID: 20857523 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 27 Sep 2010 10:00:00 pm
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Irritable Bowel Syndrome (IBS) - news item 135 of 137
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Myocardial Tissue Characterization and Aortic Stenosis
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In this issue of JASE, Fijalkowski et al. describe an improvement in myocardial reflectivity induced by aortic valve replacement (AVR) in severe aortic stenosis (AS), using integrated backscatter (IBS) analysis, one of the ultrasonic methods for tissue characterization currently available. Furthermore, they found that IBS parameters have a predictive value for...
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RSS Source: Med Worm - Irritable Bowel Symdrome Fri, 24 Sep 2010 4:12:54 am
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Irritable Bowel Syndrome (IBS) - news item 136 of 137
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Recognition and discrimination of target mRNAs by Sib RNAs, a cis-encoded sRNA family
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Five Sib antitoxin RNAs, members of a family of cis-encoded small regulatory RNAs (sRNAs) in Escherichia coli, repress their target mRNAs, which encode Ibs toxins. This target repression occurs only between cognate sRNA–mRNA pairs with an exception of ibsA. We performed co-transformation assays to assess the ability of SibC derivatives...
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RSS Source: Med Worm - Irritable Bowel Symdrome Tue, 21 Sep 2010 2:24:17 pm
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Irritable Bowel Syndrome (IBS) - news item 137 of 137
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For TEN YEARS Lucy was told not to worry about stomach cramps. In fact, a chronic disease was eating away at her gut
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Her symptoms were dismissed as a grumbling appendix (‘mild’ appendicitis) or irritable bowel syndrome (IBS). (Source: the Mail online | Health)
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RSS Source: Med Worm - Irritable Bowel Symdrome Mon, 20 Sep 2010 11:31:34 pm
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