Lung Cancer - news item 1 of 144
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Percentage Smokers Lung Cancer
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What percentage of smokers get lung cancer? We know that smoking is responsible for a large percent of lung cancers, but what are the statistics? (Source: About.com Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Fri, 4 Mar 2011 11:00:00 pm
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Lung Cancer - news item 2 of 144
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Connection detected between sudden cessation of smoking and imminent lung cancer diagnosis
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Campling BG. J Thorac Oncol. 2011;6:517-524. (Source: HemOncToday.com)
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RSS Source: Med Worm - Lung Cancer Fri, 4 Mar 2011 4:16:00 pm
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Lung Cancer - news item 3 of 144
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Blood protein may improve lung cancer diagnosis and treatment
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Patients with lung cancer have significantly higher levels of serum amyloid A protein than healthy controls, indicating that the protein may serve as a useful marker of lung adenocarcinoma, say researchers. (Source: MedWire News - Oncology)
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RSS Source: Med Worm - Lung Cancer Fri, 4 Mar 2011 2:27:51 pm
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Lung Cancer - news item 4 of 144
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Cancer Patients' Partners Become Ill Themselves
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Katarina Sjövall has studied partners of individuals with colorectal cancer, lung cancer, breast cancer or prostate cancer. The study shows that the number of diagnosed diseases among partners increased by 25 per cent after the cancer diagnosis. "Having a close relative with cancer entails worry and anxiety and an increased...
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RSS Source: Med Worm - Lung Cancer Fri, 4 Mar 2011 10:00:00 am
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Lung Cancer - news item 5 of 144
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Europe Approves Esbriet, Its First Deadly Lung Cancer Drug
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Idiopathic pulmonary fibrosis (IPF) is a serious condition that has no cure. Many people live only about three to five years after diagnosis. The most common cause of death related to IPF is respiratory failure. However, the European Union (EU) has renewed the fight against IPF by clearing the first...
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RSS Source: Med Worm - Lung Cancer Fri, 4 Mar 2011 8:00:00 am
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Lung Cancer - news item 6 of 144
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Protein Discovery Could Lead To A Diagnostic Test For Lung Cancer And Development Of Drugs That Stop Metastasis
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Scientists are reporting discovery of a protein in the blood of lung cancer patients that could be used in a test for the disease - difficult to diagnose in its earliest and most treatable stages - and to develop drugs that stop lung cancer from spreading. Their study appears in...
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RSS Source: Med Worm - Lung Cancer Fri, 4 Mar 2011 8:00:00 am
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Lung Cancer - news item 7 of 144
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TOF PET Images Compared To Conventional PET Images: Improved Detection, Better For Patients
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For the first time, quantitative - not qualitative - data analysis has demonstrated that time-of-flight (TOF) positron emission tomography (PET) scans can improve cancer detection. Research published in the March issue of The Journal of Nuclear Medicine shows that oncologic TOF fluorodeoxyglucose (FDG) PET scans yielded significant improvements in lesion...
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RSS Source: Med Worm - Lung Cancer Fri, 4 Mar 2011 7:00:00 am
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Lung Cancer - news item 8 of 144
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IASLC to help advocacy organizations attend 14th World Conference on Lung Cancer in Amsterdam
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(International Association for the Study of Lung Cancer) Lung and thoracic cancer advocacy organizations are invited to apply for travel awards to send their representatives to the 14th World Conference on Lung Cancer, to be held July 3-7, 2011, in Amsterdam. (Source: EurekAlert! - Medicine and Health)
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RSS Source: Med Worm - Lung Cancer Fri, 4 Mar 2011 4:00:00 am
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Lung Cancer - news item 9 of 144
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Ect2 Is Regulated by PKC{iota}-mediated Phosphorylation [Signal Transduction]
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The Rho GTPase guanine nucleotide exchange factor Ect2 is genetically and biochemically linked to the PKCι oncogene in non-small cell lung cancer (NSCLC). Ect2 is overexpressed and mislocalized to the cytoplasm of NSCLC cells where it binds the oncogenic PKCι-Par6 complex, leading to activation of the Rac1 small GTPase. Here,...
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 11:00:00 pm
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Lung Cancer - news item 10 of 144
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Health Highlights: March 3, 2011
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Most U.S. Nursing Homes Employ People With Criminal Records: Report Researchers Retract Lung Cancer Study Surgeons Announce First Artificial Bronchus Graft Loss of Unborn Baby Affects Women for Years: Study Long-term Use of Popular Heartburn Drugs May Lower Magnesium Levels: FDA (Source: The Doctors Lounge - Health News)
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 3:24:00 pm
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Lung Cancer - news item 11 of 144
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World's first artificial partial lung transplant 'a success'
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The world's first artificial partial lung transplant carried out on a 78-year-old patient with lung cancer has been declared a success, two and a half years after the operation took place. (Source: Telegraph Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very...
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 3:16:40 pm
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Lung Cancer - news item 12 of 144
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Investigation of Differences in P53 Gene Polymorphisms between Schizophrenia and Lung Cancer Patients in the Turkish Population
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Conclusion. The results of this study suggest a protective effect of A1 allele against lung cancer, and the p53 MspI polymorphism may modify the susceptibility to lung cancer as a single factor rather than in combination with BstUI polymorphism. (Source: Anesthesiology Research and Practice)
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 2:12:13 pm
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Lung Cancer - news item 13 of 144
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Retraction: A Genomic Strategy to Refine Prognosis in Early-Stage Non†Small-Cell Lung Cancer. N Engl J Med 2006;355:570-80
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New England Journal of Medicine, Volume 0, Issue 0, Ahead of Print. (Source: New England Journal of Medicine)
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 7:00:22 am
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Lung Cancer - news item 14 of 144
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Vitamin D linked to lung cancer survival
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ANN ARBOR, Mich., March 3 (UPI) -- The level of an enzyme that plays a role in metabolizing vitamin D -- CYP24A1 -- can predict lung cancer survival, U.S. researchers say. (Source: Health News - UPI.com)
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 4:37:02 am
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Lung Cancer - news item 15 of 144
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Test Identifies Aggressive Lung Cancer in Non-Smokers
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(Ivanhoe Newswire) -- Lung cancer is considered the 6th most common cause of cancer deaths in the United States. (Source: Medical Headlines From Ivanhoe.com)
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 4:00:00 am
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Lung Cancer - news item 16 of 144
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Blood protein in lung cancer could improve diagnosis and treatment
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Scientists are reporting discovery of a protein in the blood of lung cancer patients that could be used in a test for the disease -- difficult to diagnose in its earliest and most treatable stages -- and to develop drugs that stop lung cancer from spreading. (Source: ScienceDaily Headlines) MedWorm...
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 2:52:42 am
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Lung Cancer - news item 17 of 144
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Small cell lung cancer in an elderly patient: efficacy of somatostatin analog treatment, a case report.
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Authors: Bearz A, Lleshi A, Perin T, Fratino L, Venturini S, Giacalone A, Sartor I, Berretta M, Sulfaro S, Tirelli U PMID: 21358216 [PubMed - in process] (Source: Onkologie)
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 2:45:04 am
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Lung Cancer - news item 18 of 144
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Tumor lysis syndrome in small cell lung cancer: a case report and review of the literature.
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Authors: Jallad B, Hamdi T, Latta S, Alhosaini MN, Kheir F, Iroegbu N PMID: 21358219 [PubMed - in process] (Source: Onkologie)
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RSS Source: Med Worm - Lung Cancer Thu, 3 Mar 2011 2:45:04 am
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Lung Cancer - news item 19 of 144
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Lung Disease May Raise Risk of Lung Cancer
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As I wrote this title I can already hear my kids. "Mom - is there anything that doesn't raise the risk of cancer?" So I'll jump to my defense first. Lung cancer is most treatable in the earlier stages of the disease. If people know they are at risk, perhaps...
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RSS Source: Med Worm - Lung Cancer Wed, 2 Mar 2011 11:00:00 pm
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Lung Cancer - news item 20 of 144
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Chemoprevention of lung carcinogenesis by the combination of aerosolized budesonide and oral pioglitazone in A/J mice
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AbstractBudesonide, a synthetic glucocorticoid used for treating asthma, and pioglitazone, a synthetic peroxisome proliferatorâ€activated receptors γ ligand used for the treatment of diabetes, were evaluated for their combinational chemopreventive efficacy on mouse lung cancer using female A/J mice with benzo(a)pyrene used as the carcinogen. All chemopreventive treatments began 2â€wk postâ€carcinogen...
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RSS Source: Med Worm - Lung Cancer Wed, 2 Mar 2011 11:00:00 pm
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Lung Cancer - news item 21 of 144
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Authors Retract Paper on NSCLC Prognosis
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(MedPage Today) -- Citing an inability to replicate their findings, researchers have retracted their much-cited 2006 study in the New England Journal of Medicine that promised to identify non-small cell lung cancer patients who could benefit from adjuvant chemotherapy. (Source: MedPage Today Pulmonary) MedWorm Message: Watch the new MedWorm demo...
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RSS Source: Med Worm - Lung Cancer Wed, 2 Mar 2011 10:43:09 pm
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Lung Cancer - news item 22 of 144
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David Cockayne obituary
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Scientist who played a key role in the field of electron microscopyIn the late 1950s and 60s, pioneering advances were made in the study of the interior structures of crystals by passing high-energy electrons through thin foils in an electron microscope. David Cockayne, who has died from lung cancer aged...
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RSS Source: Med Worm - Lung Cancer Wed, 2 Mar 2011 5:15:58 pm
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Lung Cancer - news item 23 of 144
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A Future With Fewer Cases Of Lung Cancer Requiring Lymph Node Dissection
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Lymph node dissection, the current standard surgical treatment for localized non-small cell lung cancers, may be unnecessary in certain screen-detected early stage cases , according to a study published in the March issue of the Journal of Thoracic Oncology (JTO), the official journal of the International Association for the Study of...
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RSS Source: Med Worm - Lung Cancer Wed, 2 Mar 2011 11:00:00 am
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Lung Cancer - news item 24 of 144
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Finding It Easy To Quit Smoking Could Be An Early Symptom Of Lung Cancer
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Many longtime smokers quit spontaneously with little effort shortly before their lung cancer is diagnosed, leading some researchers to speculate that sudden cessation may be a symptom of lung cancer. Most patients who quit did so before noticing any symptoms of cancer, according to the study, which was published in...
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RSS Source: Med Worm - Lung Cancer Wed, 2 Mar 2011 11:00:00 am
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Lung Cancer - news item 25 of 144
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Study Links Vitamin D To Lung Cancer Survival
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Recent research suggests vitamin D may be able to stop or prevent cancer. Now, a new study finds an enzyme that plays a role in metabolizing vitamin D can predict lung cancer survival. The study, from researchers at the University of Michigan Comprehensive Cancer Center, suggests that this enzyme stops...
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RSS Source: Med Worm - Lung Cancer Wed, 2 Mar 2011 9:00:00 am
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Lung Cancer - news item 26 of 144
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Chemoradiotherapy Prior To Surgery Improves Survival In Non-Small Lung Cancer
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Researchers from Boston University School of Medicine (BUSM) have found that patients with node negative T3 and T4 non-small lung cancer who underwent chemotherapy before surgery had more than three times the survival rate than patients who only underwent surgery. These findings currently appear on-line in the Journal of Thoracic...
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RSS Source: Med Worm - Lung Cancer Wed, 2 Mar 2011 7:00:00 am
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Lung Cancer - news item 27 of 144
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Identification of annexin A1 as a proinvasive and prognostic factor for lung adenocarcinoma
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In conclusion, annexin A1 expression correlated with tumor stage, lymph node metastasis, relapse, and patient survival. Annexin A1 is proposed to function importantly in the progression of lung AdC. Content Type Journal ArticlePages 1-13DOI 10.1007/s10585-011-9380-1Authors Ying-Fu Liu, Department of Basic Medical Sciences, Medical College, Xiamen University, 168# Daxue Road, Xiamen,...
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RSS Source: Med Worm - Lung Cancer Wed, 2 Mar 2011 6:48:10 am
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Lung Cancer - news item 28 of 144
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Fish Oil May Help Lung Cancer Patients Maintain Weight
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Just last week I wrote about a study in which fish oil combined with chemotherapy for lung cancer improved the response and possibly survival. Now another study suggests fish oil may help with maintaining weight and muscle mass as well....Read Full Post (Source: About.com Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 11:00:00 pm
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Lung Cancer - news item 29 of 144
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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
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Authors: Ingrid E. Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto, Wendy Sandoval, Daniel J. Anderson, Elizabeth Helgason, James A. Ernst, Mike Eby, Jinfeng Liu, Lisa D. Belmont, Josh S. Kaminker, Karen M. O’Rourke, Kanan Pujara, Pawan Bir Kohli, Adam R. Johnson, Mark L. Chiu, Jennie R. Lill, Peter K. Jackson,...
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 11:00:00 pm
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Lung Cancer - news item 30 of 144
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Fish Oil May Help Cancer Patients Maintain Weight
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Supplementation with fish oil may help non-small-cell lung cancer patients maintain weight and muscle mass during chemotherapy, according to research published online Feb. 28 in Cancer. (Source: Modern Medicine)
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 11:00:00 pm
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Lung Cancer - news item 31 of 144
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Lung Cancer Prevention Non-Smokers
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Since lung cancer in non-smokers is the 7th leading cause of cancer deaths each year, lung cancer prevention in non-smokers is a very important topic. Being aware of lung cancer causes such as radon, secondhand smoke, and environmental exposures is critical if we want to understand lung cancer prevention in...
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 11:00:00 pm
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Lung Cancer - news item 32 of 144
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Subsequent chemotherapy reverses acquired tyrosine kinase inhibitor resistance and restores response to tyrosine kinase inhibitor in advanced non-small-cell lung cancer
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Conclusion: NSCLC patients with acquired TKI resistance should be managed aggressively whenever possible. Subsequent chemotherapy and target treatment is one of the reasonable choices for those with an initial dramatic clinical response with erlotinib/gefitinib treatment. Further studies are warranted to substantiate the association of erlotinib /gefitinib treatment with the efficacy...
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 11:00:00 pm
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Lung Cancer - news item 33 of 144
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Admixture mapping of lung cancer in 1812 African-Americans
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Lung cancer continues to be the leading cause of cancer death in the USA and the best example of a cancer with undisputed evidence of environmental risk. However, a genetic contribution to lung cancer has also been demonstrated by studies of familial aggregation, family-based linkage, candidate gene studies and most...
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 11:00:00 pm
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Lung Cancer - news item 34 of 144
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Vitamin D linked to lung cancer survival, study suggests
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Recent research suggests vitamin D may be able to stop or prevent cancer. Now, a new study finds an enzyme that plays a role in metabolizing vitamin D can predict lung cancer survival. (Source: ScienceDaily Headlines)
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 6:00:00 pm
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Lung Cancer - news item 35 of 144
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Lymph node dissection is not essential in small screen-detected lung cancers, new research shows
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(International Association for the Study of Lung Cancer) Lymph node dissection, the current standard surgical treatment for localized non-small cell lung cancers, may be unnecessary in certain screen-detected early stage cases. (Source: EurekAlert! - Medicine and Health)
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 4:00:00 am
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Lung Cancer - news item 36 of 144
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Spontaneous smoking cessation may be an early symptom of lung cancer, research suggests
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(International Association for the Study of Lung Cancer) Many longtime smokers quit spontaneously with little effort shortly before their lung cancer is diagnosed, leading some researchers to speculate that sudden cessation may be a symptom of lung cancer. (Source: EurekAlert! - Medicine and Health) MedWorm Message: Watch the new MedWorm...
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 4:00:00 am
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Lung Cancer - news item 37 of 144
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A precursor microRNA in a cancer cell nucleus: Get me out of here!
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Authors: Melo SA, Esteller M In line with their broad-based effects, microRNAs (miRNAs), small non-coding RNA molecules ~22 nucleotides long that silence target mRNAs, are thought to act as oncogenes or tumor suppressor genes based on their inhibition of tumor-suppressive and oncogenic mRNAs, respectively. We and others previously showed that...
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RSS Source: Med Worm - Lung Cancer Tue, 1 Mar 2011 3:17:09 am
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Lung Cancer - news item 38 of 144
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[Symptoms and diagnostics of lung neuroendocrine tumors.]
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Authors: Tamási L, Müller V Pulmonary neuroendocrine tumors comprise 20% of all lung cancers. They are separated into 4 subgroups: typical carcinoid tumor, atypical carcinoid tumor, large-cell neuroendocrine carcinoma, and small-cell lung carcinoma. The major symptoms present in 60% of patients are cough, hemoptysis, and obstructive pneumonia. They may also...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 39 of 144
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[News] Explaining trends in lung cancer deaths in women
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Lung cancer mortality rates in British women are stabilising but not yet falling, contrary to some press reports. The UK has one of the highest death rates in Europe for lung cancer in women; in 2007†08, over 15 000 women in the UK died of the disease. “Lung cancer is...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 40 of 144
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[Editorial] Cancer in developing countries: can the revolution begin?
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On Feb 4, 2011, World Cancer Day once again had the theme “Cancer can be preventedâ€. A few days later, European cancer mortality predictions for 2011 were published reporting a downward trend in mortality for nearly all cancers studied. The report highlighted that nearly 1·3 million cancer deaths are predicted...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 41 of 144
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A Population-Based Assessment of Specialty Physician Involvement in Cancer Clinical Trials
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Conclusions Features of specialty physicians’ practice environments are associated with their trial participation, but many physicians at CCOPs and cancer centers do not participate. (Source: JNCI) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 42 of 144
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MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer [Medical Sciences]
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The efficacy of computed tomography (CT) screening for early lung cancer detection in heavy smokers is currently being tested by a number of randomized trials. Critical issues remain the frequency of unnecessary treatments and impact on mortality, indicating the need for biomarkers of aggressive disease. We explored microRNA (miRNA) expression...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 43 of 144
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Impaired endothelial progenitor cell mobilization and colonyâ€forming capacity in chronic obstructive pulmonary disease
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Conclusions:  The number of circulating EPC and EPCâ€CFU was not increased during thoracic surgery in COPD patients. These results indicate that both the mobilization and proliferative capacity of EPC are severely impaired in COPD patients. (Source: Respirology)
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 44 of 144
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The WST survival assay: an easy and reliable method to screen radiation-sensitive individuals
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An easy, fast and reliable method was developed to screen hundreds of Epstein–Barr virus-transformed cell lines (lymphoblastoid cell lines, LCLs) for radiation sensitivity that were generated from lymphocytes isolated from young lung cancer patients. The WST-1 test explores the metabolic activity of the mitochondria as an indicator for the vital...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 45 of 144
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Modelling lung cancer due to radon and smoking in WISMUT miners: preliminary results
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A mechanistic two-stage carcinogenesis model has been applied to model lung-cancer mortality in the largest uranium-miner cohort available. Models with and without smoking action both fit the data well. As smoking information is largely missing from the cohort data, a method has been devised to project this information from a...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 46 of 144
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Mediastinal Staging Procedures in Non-Small Cell Lung Cancer--Reply [Letters]
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(Source: JAMA) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 47 of 144
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Mediastinal Staging Procedures in Non-Small Cell Lung Cancer [Letters]
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(Source: JAMA)
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 48 of 144
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Tobacco firms move to stop FDA banning menthol cigarettes
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(Source: BMJ Online First)
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 49 of 144
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Conference report: Erlotinib comparable efficacy to chemotherapy for NSCLC
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Source: BioSpace Area: News According to findings from the TITAN study presented at the European Multidisciplinary Conference in Thoracic Oncology, erlotinib has comparable efficacy to standard chemotherapy in the second-line treatment of patients with non-small cell lung cancer (NSCLC). The open-label study randomised patients with NSCLC that had progressed after...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 50 of 144
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Small study suggests fish oil supplements may help prevent weight and muscle loss during chemotherapy for NSCLC
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Source: Cancer Area: News According to the results of a small open-label study published early online in the journal Cancer, fish oil supplementation may help patients to maintain their weight and muscle mass during chemotherapy for non-small cell lung cancer (NSCLC). The authors note that involuntary weight loss is a...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 51 of 144
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Two Consecutive Cases of Platinum-Refractory Pulmonary Pleomorphic Carcinoma that Showed Dramatic Responses to MAID (Mesna, Doxorubicin, Ifosfamide and Dacarbazine) Chemotherapy
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This report describes two consecutive patients with platinum-refractory pulmonary pleomorphic carcinoma who received doxorubicin, ifosfamide plus dacarbazine chemotherapy. Both patients showed dramatic responses to this combination chemotherapy and the treatment effect was sustained for 7 and 9 months, respectively. Our report strongly suggests that the treatment approaches to patients with...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 52 of 144
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The Influence of Health Behaviors on Survival in Lung Cancer Patients in Taiwan
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Conclusions This study presented evidence showing that smoking, alcohol consumption behavior, routine physical check-ups and stage at diagnosis play an important role in determining the survival of lung cancer patients. (Source: Japanese Journal of Clinical Oncology)
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 11:00:00 pm
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Lung Cancer - news item 53 of 144
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Much overlooked causes of lung cancer.
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Authors: Hajdu SI PMID: 21325264 [PubMed - in process] (Source: Annals of Clinical and Laboratory Science)
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 10:45:06 pm
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Lung Cancer - news item 54 of 144
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Fish Oil Fights Wasting During Chemo (CME/CE)
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(MedPage Today) -- Fish oil supplements may help prevent weight and muscle loss during chemotherapy for non-small cell lung cancer (NSCLC), according to results from a small open-label study. (Source: MedPage Today Hematology/Oncology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest,...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 5:13:07 pm
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Lung Cancer - news item 55 of 144
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Study Uncovers Mechanisms That Control Rb2/p130 Gene Expression In Lung Cancer
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Despite innumerable studies on lung cancer, many aspects of the disease have yet to be understood, including the role played by the retinoblastoma-related protein Rb2/p130 in the evolution of the disease... (Source: Health News from Medical News Today)
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 7:00:00 am
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Lung Cancer - news item 56 of 144
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Aggressive Type Of Lung Cancer In Never-Smokers Identified By Quick, Easy Test
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An inexpensive and rapid testing method can effectively identify a sub-group of never-smoking lung cancer patients whose tumors express a molecule associated with increased risk of disease progression or recurrence, US researchers have found. Dr Ping Yang from the Mayo Clinic, Rochester, USA, and colleagues, reported the findings at the...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 7:00:00 am
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Lung Cancer - news item 57 of 144
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Oncogene AEG-1 Strongly Predicts Response To Erlotinib Treatment In EGFR-Mutant Lung Cancer
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Spanish researchers have identified a gene whose expression level strongly predicts how well certain lung cancer patients will respond to treatment with the drug erlotinib. Dr Rafael Rosell and colleagues reported their findings at the European Multidisciplinary Conference in Thoracic Oncology (EMCTO), 24-26 February 2011 in Lugano, Switzerland. The researchers...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 7:00:00 am
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Lung Cancer - news item 58 of 144
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Bone Drug Zoledronic Acid May Help Prevent Spread Of Early Lung Cancer
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A drug that is currently used to help treat bone metastases in patients with lung cancer could also be useful at an earlier stage of treatment, to prevent the cancer from spreading in the first place, Italian researchers have found. Dr Michela Quirino and colleagues from the Catholic University of...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 7:00:00 am
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Lung Cancer - news item 59 of 144
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BUSM study shows chemoradiotherapy prior to surgery improves survival
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(Boston University Medical Center) Researchers from Boston University School of Medicine have found that patients with node negative T3 and T4 non-small lung cancer who underwent chemotherapy before surgery had more than three times the survival rate than patients who only underwent surgery. (Source: EurekAlert! - Medicine and Health) MedWorm...
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 4:00:00 am
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Lung Cancer - news item 60 of 144
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Lung Cancer in 2010: One Size Does Not Fit All
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2010 saw continued advancement in our understanding of the molecular genetics of lung cancer and of specific targeted inhibitors with remarkable clinical benefit in selected populations. Nature Reviews Clinical Oncology (Source: Medscape Today Headlines)
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RSS Source: Med Worm - Lung Cancer Mon, 28 Feb 2011 3:00:00 am
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Lung Cancer - news item 61 of 144
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Man with Prostate, Lung, and Thyroid Cancer to Embark on 2600 Mile Trek
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A man with three types of diagnosed cancer including stage 4 lung cancer says he will embark on a 2600 mile trek along the entire length of the Pacific Coast Trail which stretches from Mexico into Canada....Read Full Post (Source: About.com Prostate Cancer) MedWorm Message: Watch the new MedWorm demo...
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RSS Source: Med Worm - Lung Cancer Sun, 27 Feb 2011 11:00:00 pm
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Lung Cancer - news item 62 of 144
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Nutritional intervention with fish oil provides a benefit over standard of care for weight and skeletal muscle mass in patients with nonsmall cell lung cancer receiving chemotherapy
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CONCLUSIONS:Nutritional intervention with 2.2 g of FO per day appears to provide a benefit over SOC, resulting in the maintenance of weight and muscle mass during chemotherapy. Cancer 2011. © 2011 American Cancer Society. (Source: Cancer)
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RSS Source: Med Worm - Lung Cancer Sun, 27 Feb 2011 11:00:00 pm
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Lung Cancer - news item 63 of 144
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GABAB receptor antibodies in limbic encephalitis and anti-GAD-associated neurologic disorders
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Conclusions: GABABR-ab are the most common antibodies found in LE associated with SCLC previously considered "seronegative." In patients with GAD-ab, the frequency of GABABR-ab is low and only observed in the context of cancer. (Source: Neurology)
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RSS Source: Med Worm - Lung Cancer Sun, 27 Feb 2011 11:00:00 pm
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Lung Cancer - news item 64 of 144
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MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14)
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Authors: R Wang, Z-X Wang, J-S Yang, X Pan, W De & L-B Chen (Source: Oncogene)
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RSS Source: Med Worm - Lung Cancer Sun, 27 Feb 2011 11:00:00 pm
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Lung Cancer - news item 65 of 144
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Automatic definition of the central-chest lymph-node stations
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Conclusions The system accurately defines the regional nodal stations in a given high-resolution 3D MDCT chest scan and eases a physician’s burden for analyzing a given MDCT scan for lymph-node station assessment. It also shows potential as an aid for preplanning lung-cancer staging procedures. Content Type Journal ArticlePages 1-17DOI 10.1007/s11548-011-0547-7Authors...
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RSS Source: Med Worm - Lung Cancer Sat, 26 Feb 2011 8:43:25 pm
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Lung Cancer - news item 66 of 144
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Synta Announces Phase 2b/3 Trial For Ganetespib (STA-9090) In Advanced 2nd-Line Non-Small Cell Lung Cancer
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Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that a Phase 2b/3 clinical trial of ganetespib (STA-9090) in combination with docetaxel in non-small cell lung cancer (NSCLC) will be initiated in the second quarter of 2011. (...
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RSS Source: Med Worm - Lung Cancer Sat, 26 Feb 2011 3:36:00 pm
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Lung Cancer - news item 67 of 144
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Targeted Lung Cancer Drug, Crizotinib Shows Promise in Typically Unresponsive Non†Small-Cell Lung Cancer
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Pfizer’s crizotinib, an oral, selective, small-molecule inhibitor for non-small cell lung cancer (NSCLC) has gone remarkably fast from lab bench to late-stage trials and now to the FDA for review. (Source: Cancer Network)
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RSS Source: Med Worm - Lung Cancer Sat, 26 Feb 2011 2:00:01 pm
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Lung Cancer - news item 68 of 144
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Cheap, fast test for type of lung cancer
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LUGANO, Switzerland, Feb. 25 (UPI) -- An inexpensive and rapid test can effectively identify a sub-group of lung cancer for patients who have never smoked, U.S. researchers say. (Source: Health News - UPI.com) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest,...
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RSS Source: Med Worm - Lung Cancer Sat, 26 Feb 2011 3:11:44 am
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Lung Cancer - news item 69 of 144
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Molecular mechanisms that control Rb2/p130 gene expression in lung cancer explored
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A new study uncovers mechanisms that control Rb2/p130 gene expression in lung cancer and reveals why the gene is expressed differently in small and non-small lung cancer cells. (Source: ScienceDaily Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized...
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RSS Source: Med Worm - Lung Cancer Fri, 25 Feb 2011 4:00:00 am
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Lung Cancer - news item 70 of 144
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New study finds molecular mechanisms that control Rb2/p130 gene expression in lung cancer
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(Sbarro Health Research Organization) A new study uncovers mechanisms that control Rb2/p130 gene expression in lung cancer and reveals why the gene is expressed differently in small and non-small lung cancer cells. (Source: EurekAlert! - Medicine and Health)
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RSS Source: Med Worm - Lung Cancer Fri, 25 Feb 2011 4:00:00 am
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Lung Cancer - news item 71 of 144
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Quick, easy test identifies aggressive type of lung cancer in never-smokers
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(European Society for Medical Oncology) An inexpensive and rapid testing method can effectively identify a sub-group of never-smoking lung cancer patients whose tumors express a molecule associated with increased risk of disease progression or recurrence, US researchers have found (Source: EurekAlert! - Medicine and Health)
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RSS Source: Med Worm - Lung Cancer Fri, 25 Feb 2011 4:00:00 am
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Lung Cancer - news item 72 of 144
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Whole-Tumor Perfusion CT in Patients with Advanced Lung Adenocarcinoma Treated with Conventional and Antiangiogenetic Chemotherapy: Initial Experience [Thoracic Imaging]
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Conclusion: Perfusion CT imaging may allow evaluation of lung cancer angiogenesis demonstrating alterations in vascularity following treatment. © RSNA, 2011 (Source: Continuous Publishing articles)
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 73 of 144
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Phase I Study of Navitoclax (ABT-263), a Novel Bcl-2 Family Inhibitor, in Patients With Small-Cell Lung Cancer and Other Solid Tumors [Thoracic Oncology]
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Conclusion Navitoclax is safe and well tolerated, with dose-dependent thrombocytopenia as the major adverse effect. Preliminary efficacy data are encouraging in SCLC. Efficacy in SCLC and the utility of pro-GRP as a marker of treatment response will be further evaluated in phase II studies. (Source: Journal of Clinical Oncology)
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 74 of 144
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Clinical Dutch-English Lambert-Eaton Myasthenic Syndrome (LEMS) Tumor Association Prediction Score Accurately Predicts Small-Cell Lung Cancer in the LEMS [Thoracic Oncology]
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Conclusion The simple clinical DELTA-P score discriminated patients with LEMS with and without SCLC with high accuracy early in the course of LEMS. (Source: Journal of Clinical Oncology)
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 75 of 144
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Pathologic Complete Responses After Chemotherapy Plus Figitumumab in Stage IV Non-Small-Cell Lung Cancer [DIAGNOSIS IN ONCOLOGY]
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(Source: Journal of Clinical Oncology)
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 76 of 144
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Lung Cancer in Association With Yellow Nail Syndrome [DIAGNOSIS IN ONCOLOGY]
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(Source: Journal of Clinical Oncology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 77 of 144
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High Prevalence of Lung Cancer in a Surgical Cohort of Lung Cancer Patients A Decade After Smoking Cessation
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This study was designed to assess the prevalence of smoking at time of lung cancer diagnosis in a surgical patient cohort referred for cardiothoracic surgery. Methods: Retrospective study of lung cancer patients (n= 626) referred to three cardiothoracic surgeons at a tertiary care medical center in Southern California from January...
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 78 of 144
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Reply to Mier [Letters to the Editor]
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(Source: European Journal of Cardio-Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 79 of 144
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Pleural suction or not, in the lung resections? Role of the digital thoracic drainages [Letters to the Editor]
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(Source: European Journal of Cardio-Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 80 of 144
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Reply to Mordant et al. [Letters to the Editor]
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(Source: European Journal of Cardio-Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 81 of 144
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Concordance between epidermal growth factor receptor status in primary non-small-cell lung cancer and metastases: still to be established [Letters to the Editor]
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(Source: European Journal of Cardio-Thoracic Surgery) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 82 of 144
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How successful is lung-preserving radical surgery in the mesothelioma and radical surgery-trial environment? A case-controlled analysis [Original articles]
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Conclusion: Radical open-lung-sparing surgery may confer a survival advantage to patients with malignant mesothelioma, who are fit to undergo radical decortication followed by chemotherapy and radiotherapy. Trials of radical surgery versus no surgery should include lung-sparing operations. (Source: European Journal of Cardio-Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 83 of 144
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Determining the appropriate sleeve lobectomy versus pneumonectomy ratio in central non-small cell lung cancer patients: an audit of an aggressive policy of pneumonectomy avoidance [Original articles]
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Conclusions: Parenchyma-sparing procedures can reduce the PN rate to less than 10%. A PN:SL index lower than 1:1.5 as a quality standard in a specialised thoracic unit should encourage the use of broncho-angioplastic procedures and improve patient outcomes. Long-term survival, QoL, postoperative lung function test and tolerance of adjuvant therapies...
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 84 of 144
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Is radiofrequency thermal ablation a safe and effective procedure in the treatment of pulmonary malignancies? [Original articles]
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Conclusion: RAF is a safe and well-tolerated procedure with satisfied efficacy in the treatment of malignant lung nodules. To avoid complications with potential fatal outcome, adequate training and careful patient selection by a multidisciplinary team might be helpful. (Source: European Journal of Cardio-Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 85 of 144
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Targeting PKC mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid Leukemiaâ€Derived cell lines and blast cells
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AbstractRecent studies in acute myeloid leukemia (AML) suggest activation of proâ€proliferative signaling cascades including those mediated by Protein Kinase C (PKC) represent a poor prognostic factor for patients. The classical PKC isoforms α and β generally support survival signaling and have emerged as important targets for antiâ€cancer therapy. Enzastaurin is...
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 11:00:00 pm
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Lung Cancer - news item 86 of 144
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American Cancer Society announces Cancer Facts & Figures for African Americans, 2011-2012 available
|
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The report finds:Death rates among African Americans for all cancers combined have been decreasing since the early 1990s. The decline has been larger in men (2.5% per year since 1995) than in women (1.5% per year since 1999). A similar decline in death rates has been observed among whites since...
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 8:55:00 pm
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Lung Cancer - news item 87 of 144
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Targeting angiogenesis from multiple pathways simultaneously: BIBF 1120, an investigational novel triple angiokinase inhibitor
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Summary Angiogenesis is considered one of the major components of tumor progression and metastasis. Interfering with the formation and stabilization of tumor blood vessels could increase tumor response rates and may translate into improved clinical outcomes in cancer patients. The clinical efficacy demonstrated in phase III trials with bevacizumab, a...
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 4:23:18 pm
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Lung Cancer - news item 88 of 144
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Higher levels of compound in blood associated with lower risk of respiratory disease
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An analysis of data including more than 500,000 adults indicates that levels in the blood of bilirubin (a compound produced by the breakdown of hemoglobin from red blood cells) in the normal range but relatively higher were associated with a reduced risk of lung cancer, chronic obstructive pulmonary disease and...
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 9:00:00 am
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Lung Cancer - news item 89 of 144
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Radiotherapy in rectal cancer: development, adequacy and radiotherapy utilisation rate. A comparative analysis with the most frequent tumour sites
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Conclusions The “radiotherapy utilisation rate†for rectal cancer was equivalent to the estimated optimum rate as defined on the basis of reference groups. The therapy utilised developed chronologically in parallel with the available scientific evidence. The radiotherapy utilisation rates for breast and prostate cancer gradually increased, with a tendency to...
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 6:38:02 am
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Lung Cancer - news item 90 of 144
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Stem cell and lung cancer development: blaming the Wnt, Hh and Notch signalling pathway
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Abstract Primary lung cancer may arise from the central (bronchial) or peripheral (bronchiolo-alveolar) compartments. However the origins of the different histological types of primary lung cancer are not well understood. Stem cells are believed to be crucial players in tumour development and there is much interest in identifying those compartments...
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RSS Source: Med Worm - Lung Cancer Thu, 24 Feb 2011 6:37:55 am
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Lung Cancer - news item 91 of 144
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Genome Wide Expression Analysis of the Effect of the Chinese Patent Medicine Zilongjin Tablet on Four Human Lung Carcinoma Cell Lines
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In this study, four lung cancer cell lines, A549, H446, H460 and H520, were treated with 2.2 mg/mL of ZLJ solution for 24 h at 37 °C under 5% CO2. RNA was isolated and a microarray experiment using the Affymetrix Human Genome U133 plus 2.0 Array was employed to differentiate the expression patterns...
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 11:00:00 pm
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Lung Cancer - news item 92 of 144
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A comparison between diuretics and angiotensin-receptor blocker agents in patients with stage I hypertension (PREVER-treatment trial): study protocol for a randomized double-blind controlled trial
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DiscussionThe putative pleiotropic effects of ARB agents, particularly renal protection, have been disputed, and they have been scarcely compared with diuretics in large clinical trials, despite that they have been at least as efficacious as newer agents in managing hypertension. Even if the null hypothesis is not rejected, the information...
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 11:00:00 pm
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Lung Cancer - news item 93 of 144
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A functional single nucleotide polymorphism at the promoter region of cyclin A2 is associated with increased risk of colon, liver, and lung cancers
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CONCLUSIONS:The current results suggested that an SNP (rs769236) at the promoter of CCNA2 may be associated significantly with increased risk of colon, liver, and lung cancers. Cancer 2011;. © 2011 American Cancer Society. (Source: Cancer)
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 11:00:00 pm
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Lung Cancer - news item 94 of 144
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Prognostic significance of angiogenesis and angiogenic growth factors in nonsmall cell lung cancer
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AbstractCurrently, nonsmallâ€cell lung cancer (NSCLC) is the leading cause of cancerâ€related death in the United States. Angiogenesis, the formation of new vasculature, is a complex and tightly regulated process that promotes metastasis and disease progression in lung cancer and other malignancies. Developmental antiangiogenic agents have shown activity in NSCLC, and...
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 11:00:00 pm
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Lung Cancer - news item 95 of 144
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New cheek swab technique may detect lung cancer
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(Source: Cancer)
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 2:20:11 pm
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Lung Cancer - news item 96 of 144
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Women Have Options For Colorectal Cancer Screenings
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Although colonoscopy is the preferred method of screening for colorectal cancer, physicians should discuss all screening options with their patients, according to a new Committee Opinion released today by The American College of Obstetricians and Gynecologists. Women should be screened using the method that they are most comfortable with and...
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 11:00:00 am
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Lung Cancer - news item 97 of 144
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Hepatocellular carcinoma occurring in hepatobiliary fibropolycystic disease
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Congenital hepatic fibrosis (CHF) and bile duct hamartomas (von Meyenburg complexes) are hepatobiliary fibropolycystic diseases. There have been several reports of liver neoplasias arising in hepatobiliary fibropolycystic diseases. However, most of them were cholangiocarcinomas and cases involving hepatocellular carcinoma (HCC) are rare. A 51â€yearâ€old woman was found to have multiple...
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 10:30:09 am
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Lung Cancer - news item 98 of 144
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Conference Report: Early/Adjuvant Non-Small-Cell Lung Cancer
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Learning Module - Corey J. Langer, MD, FACP, and Heather Wakelee, MD, discuss new clinical findings related to screening, prognosis, and treatment of early-stage NSCLC as presented at the 2010 Multidisciplinary Symposium in Thoracic Oncology. (Source: Clinical Care Options Oncology - Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 8:51:42 am
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Lung Cancer - news item 99 of 144
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European Multidisciplinary Conference in Thoracic Oncology -- press program
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(European Society for Medical Oncology) The following studies will be presented in the Press Program of the second European Multidisciplinary Conference in Thoracic Oncology, a multipartner initiative for physicians of all medical disciplines dealing with lung cancer and other thoracic malignancies. (Source: EurekAlert! - Cancer)
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 4:00:00 am
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Lung Cancer - news item 100 of 144
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Repeat stereotactic radiosurgery in the management of brain metastases from non-small cell lung cancer.
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In conclusion, repeat SRS is a preferred option to manage brain metastases from NSCLC, leading to a long survival with a decreased neurological decline. Repeat SRS is promising to preserve neurocognition, because the convergent dose distribution decreases the unfavorable influences from radiation on germinal niches, thereby preserving neural stem cells...
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 3:30:03 am
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Lung Cancer - news item 101 of 144
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A Benefit-Risk Assessment of Erlotinib in Non-Small-Cell Lung Cancer and Pancreatic Cancer
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(Source: Drug Safety) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Lung Cancer Wed, 23 Feb 2011 1:06:11 am
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Lung Cancer - news item 102 of 144
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Krebs von den Lungenâ€6 (KLâ€6) is a prognostic biomarker in patients with surgically resected nonâ€small cell lung cancer
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AbstractBy immunizing mice with a lung adenocarcinoma cell line, we previously established a murine IgG1 monoclonal antibody that recognizes a sialylated sugar chain designated Krebs von den Lungenâ€6 (KLâ€6). KLâ€6 is a high†molecularâ€weight glycoprotein classified as a human MUC1 mucin. The aim of this study was to determine whether...
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 103 of 144
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Single-port video-assisted thoracoscopic lobectomy [Case report - Thoracic oncologic]
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We describe a case report of a 74-year-old female operated by a single-port approach for a lower-lobe VATS lobectomy. (Source: Interactive CardioVascular and Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 104 of 144
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Postoperative complications and respiratory function following segmentectomy of the lung - comparison of the methods of making an inter-segmental plane [Institutional report - Thoracic oncologic]
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Segmentectomy could be one of the standard modes of surgery for the treatment of early lung cancer. However, segmentectomy could be more difficult than lobectomy as to the management of inter-segmental plane. The relationship between methods of dividing an inter-segmental plane and postoperative complication/pulmonary function was investigated in this study....
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 105 of 144
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Vascular endothelial growth factor in pleural fluid for differential diagnosis of benign and malignant origin and its clinical applications [Institutional report - Thoracic oncologic]
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Our goal was to determine the role of vascular endothelial growth factor (VEGF) in diagnosing of pleural effusion (PE) in order to select patients deserving of more aggressive procedures. Seventy-nine consecutive patients with undiagnosed unilateral PE were enrolled. Pleural VEGF levels, measured using enzyme-linked immunosorbent assay (ELISA), were correlated to...
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 106 of 144
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Subpleural Honeycombing on High Resolution Computed Tomography is Risk Factor for Fatal Pneumonitis [ORIGINAL ARTICLES: GENERAL THORACIC]
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Conclusions Subpleural honeycombing on high-resolution computed tomography is a significant predictor of postoperative interstitial pneumonia in asymptomatic patients who undergo resection for lung cancer. (Source: The Annals of Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 107 of 144
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Invited Commentary [ORIGINAL ARTICLES: GENERAL THORACIC]
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(Source: The Annals of Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 108 of 144
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Risk Factors of Acute Kidney Injury According to RIFLE Criteria After Lung Cancer Surgery [ORIGINAL ARTICLES: GENERAL THORACIC]
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Conclusions The RIFLE classification is a valuable tool to assess AKI after lung cancer surgery. The severity of perioperative renal impairment is associated with increased mortality and morbidity. (Source: The Annals of Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 109 of 144
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Human Transplantation of a Biologic Airway Substitute in Conservative Lung Cancer Surgery [ORIGINAL ARTICLES: GENERAL THORACIC]
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Conclusions We demonstrate the feasibility of this surgical innovation to prevent the high-risk procedure of pneumonectomy in a single case. If confirmed in larger series of selected patients, it could bring new perspectives in conservative lung cancer surgery. (Source: The Annals of Thoracic Surgery) MedWorm Message: Watch the new MedWorm...
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 110 of 144
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Utility of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in the Diagnosis of Mediastinal Masses of Unknown Etiology [ORIGINAL ARTICLES: GENERAL THORACIC]
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Conclusions Endobronchial ultrasound guided transbronchial needle aspiration is a safe and minimally invasive approach for sampling of mediastinal tissues. It should be considered for evaluation of mediastinal masses of unknown origin early in the diagnoses process. It spares more invasive procedures for tissue sampling of the mediastinum. (Source: The Annals...
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 111 of 144
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Pneumonectomy for Lung Cancer: A Further Step in Minimally Invasive Surgery [HOW TO DO IT]
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We describe 2 patients with centrally located non-small cell lung cancer requiring pneumonectomy and radical lymph node dissection. The operations, consisting of a left and a right pneumonectomy, were successfully performed by a totally video-assisted robotic approach. Tips and pitfalls in this latest innovation in the minimally invasive surgery for...
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 112 of 144
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Post-Lobectomy Pulmonary Artery Stump Thrombosis: How Dangerous Is It? [IMAGES IN CARDIOTHORACIC SURGERY]
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(Source: The Annals of Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 113 of 144
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Coexistent Pulmonary Inflammatory Pseudotumor and Carcinoma in One Patient: Does Positron Emission Tomography/Computed Tomography Help [IMAGES IN CARDIOTHORACIC SURGERY]
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(Source: The Annals of Thoracic Surgery)
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 11:00:00 pm
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Lung Cancer - news item 114 of 144
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U.S. Senate Must Reject H.R.1 - American Lung Association
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Statement of Charles D. Connor, President and CEO of the American Lung Association The U.S. House of Representatives failed to protect the public health of all Americans by passing H.R.1. This bill ignores public health and will have dire consequences for all Americans, especially people with lung diseases, including lung...
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RSS Source: Med Worm - Lung Cancer Tue, 22 Feb 2011 7:00:00 am
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Lung Cancer - news item 115 of 144
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[Maintenance therapy in advanced non-small cell lung cancer: A new paradigm?]
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Authors: Pérol M, Arpin D Standard treatment of advanced non-small cell lung cancer is based on several lines of therapy separated by treatment-free intervals in which each new line is started when tumour progression is detected. The maintenance strategy consists of pursuing an appropriate, well-tolerated treatment after the end of...
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 116 of 144
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Development of topotecan loaded lipid nanoparticles for chemical stabilization and prolonged release.
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Authors: Souza LG, Silva EJ, Martins AL, Mota MF, Braga RC, Lima EM, Valadares MC, Taveira SF, Marreto RN Topotecan is an important cytotoxic drug that has gained broad acceptance in clinical use for the treatment of refractory ovarian and small-cell lung cancer. The lactone active form of topotecan can...
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 117 of 144
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Former Smokers at Risk for Lung Cancer Decades Later
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I'm often surprised by the response I get when I mention that the majority of people who develop lung cancer now are non-smokers. "What? You've gotta be kidding! Where did you hear that?"...Read Full Post (Source: About.com Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 118 of 144
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Increased killer immunoglobulin-like receptor expression and functional defects in natural killer cells in lung cancer.
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Authors: Al Omar SY, Marshall E, Middleton D, Christmas SE Frequencies of natural killer (NK) cells from patients with non-small cell lung cancer (NSCLC) or small cell lung cancer (SCLC) did not differ from healthy controls. A higher proportion of NK cells from NSCLC patients expressed the killer immunoglobulin-like receptor (...
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 119 of 144
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Lower lung cancer mortality in obesity
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Conclusion Obesity was associated with lower lung cancer mortality in this prospective cohort analysis. As the effect was rather specific for lung cancer, further studies are indicated to explore the underlying mechanism. (Source: International Journal of Epidemiology)
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 120 of 144
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ERCC1 influence on the incidence of brain metastases in patients with non-squamous NSCLC treated with adjuvant cisplatin-based chemotherapy
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Conclusions: This study suggests that adjuvant cisplatin-based chemotherapy is associated with an increased risk of BMs in patients with resected chemosensitive non-SCCs. If confirmed, these data could provide a rationale for new follow-up and/or prophylactic strategies. (Source: Annals of Oncology) MedWorm Message: Watch the new MedWorm demo and find out...
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 121 of 144
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Addition of cetuximab to first-line chemotherapy in patients with advanced non-small-cell lung cancer: a cost-utility analysis
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Conclusions: From a health economic perspective, the addition of cetuximab to standard first-line chemotherapy in patients with epidermal growth factor receptor-expressing advanced NSCLC cannot be recommended to date, due to a high ICER compared with other health care interventions. Treatment schedules resulting in more favorable cost–utility ratios should be evaluated. (...
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 122 of 144
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First-line erlotinib and bevacizumab in patients with locally advanced and/or metastatic non-small-cell lung cancer: a phase II study including molecular imaging
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Conclusions: First-line treatment with bevacizumab and erlotinib in stage IIIb/IV NSCLC resulted in an NPR of 75%. OS was however disappointing. Early response evaluation with FDG–PET is the best predictive test for PFS. (Source: Annals of Oncology)
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 123 of 144
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A randomized phase II study comparing induction or consolidation chemotherapy with cisplatin-docetaxel, plus radical concurrent chemoradiotherapy with cisplatin-docetaxel, in patients with unresectable locally advanced non-small-cell lung cancer
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Conclusion: Both study arms merit further testing in patients with limited volume stage III NSCLC. (Source: Annals of Oncology)
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 124 of 144
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EGFR gene copy number as a predictive biomarker for patients receiving tyrosine kinase inhibitor treatment: a systematic review and meta-analysis in non-small-cell lung cancer
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Conclusion: Among TKI-treated patients, increased EGFR gene copy number appears to be associated with improved survival outcomes. The effect on OS appears to be limited to patients of non-Asian descent. (Source: Annals of Oncology)
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 125 of 144
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Is FISH floating or still swimming in the lung cancer ocean?
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(Source: Annals of Oncology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 126 of 144
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Nanoscaled carborane ruthenium(II)-arene complex inducing lung cancer cells apoptosis
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Conclusion: In this study, the ruthenium(II)-arene complex could significantly induce apoptosis in human lung cancer HCC827 cell line. Treatment of HCC827 cells with the ruthenium(II)-arene complex resulted in dose-dependent cell apoptosis as indicated by high cleaved Caspase-8,9 ratio. Besides ruthenium(II)-arene complex caused a rapid induction of cleaved Caspase-3 activity and...
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 127 of 144
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Genotoxic effect of occupational exposure to cadmium
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In conclusion, the study adds more proof that Cd exposure has a genotoxic effect and highlighted the importance of using cytogenetic studies as a sensitive and effective means for early detection of Cd-induced mutagenicity (Source: Toxicology and Industrial Health current issue)
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 128 of 144
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Methylenetetrahydrofolate reductase C677T polymorphism in patients with lung cancer in a Korean population
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Conclusions: This is the first reported study focusing on the association between MTHFR C677T polymorphisms and the risk of lung cancer in a Korean population. The T allele was found to provide a weak protective association with lung squamous cell carcinoma. (Source: BMC Medical Genetics - Latest articles)
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 129 of 144
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Health consequences of pipe versus cigarette smoking
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Conclusions Between pipe and cigarette smokers, no or only minor differences were found in mortality from any cause and the specified smoking-related diseases. Pipe smoking is not safer than cigarette smoking. (Source: Tobacco Control)
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 130 of 144
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Social Normative Beliefs Regarding Cigarette Smoking in Hungarian Adolescents
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Conclusions: Youth smoking prevention programs should consider assessing and taking into account normative beliefs and develop strategies that provide accurate information about the actual prevalence of smoking, the types of individuals who smoke, and approval/disapproval of smoking by parents and peers. (Source: Pediatrics International) MedWorm Message: Watch the new MedWorm...
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 pm
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Lung Cancer - news item 131 of 144
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A New Expert System for Diagnosis of Lung Cancer: GDA†LS_SVM
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Abstract In nowadays, there are many various diseases, whose diagnosis is very hardly. Lung cancer is one of this type diseases. It begins in the lungs and spreads to other organs of human body. In this paper, an expert diagnostic system based on General Discriminant Analysis (GDA) and Least Square...
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 4:04:44 pm
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Lung Cancer - news item 132 of 144
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Ultrasensitive Characterization of Site-Specific Glycosylation of Affinity-Purified Haptoglobin from Lung Cancer Patient Plasma Using 10 μm i.d. Porous Layer Open Tubular Liquid Chromatographyâˆ'Linear Ion Trap Collision-Induced Dissociation/Electron Transfer Dissociation Mass Spectrometry
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Analytical ChemistryDOI: 10.1021/ac102825g (Source: Analytical Chemistry)
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 2:17:53 pm
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Lung Cancer - news item 133 of 144
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Canadian Cancer Society Applauds Health Canada's Release Of New Cigarette Package Warnings
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Health Canada released a set of new picture health warnings for cigarette and little cigar packages. The new labels include 16 warnings that will cover 75 per cent of the package front and back, eight additional messages to be printed inside the package (or on an insert), and four toxic...
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RSS Source: Med Worm - Lung Cancer Mon, 21 Feb 2011 11:00:00 am
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Lung Cancer - news item 134 of 144
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Role of 18F-Fluorodeoxyglucose Positron Emission Tomography in Predicting Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer.
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Conclusions. In this retrospective study, high FDG avidity (normalized SUV(max) ≥5) correlated with EGFR-wild-type genotype. Although genotyping remains the gold standard, further work to validate FDG-PET as a surrogate for tumor genotype may provide useful information in patients without available tumor tissue. PMID: 21339258 [PubMed - as supplied by publisher] (...
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 11:00:00 pm
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Lung Cancer - news item 135 of 144
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Outcomes of Patients with Advanced Non-Small Cell Lung Cancer Treated in a Phase I Clinic.
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Conclusion. Phase I clinical trials were well tolerated by selected patients with advanced NSCLC treated at M.D. Anderson. Nonsmokers and patients with a good PS survived longer. PFS in our population was shorter in smokers/ex-smokers and patients with a PS score of 2. It is reasonable to refer pretreated patients...
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 11:00:00 pm
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Lung Cancer - news item 136 of 144
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Study Shows Improved Detection Of Lung Cancer Nodules With Riverain Medical's CAD Chest X-Ray Technology
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Riverain Medical, an industry leader and innovator in computer-aided detection (CAD) and advanced visualization technologies, announced a poster presentation, "A Superior Chest X-Ray Computer-Aided Detection (CXR CADe) Application: A Reader Study," has been published on the European Society of Radiology's website. Investigators compared two versions of Riverain Medical's computer-aided detection (...
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 7:00:00 am
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Lung Cancer - news item 137 of 144
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Changes on Mitochondrial DNA Content in Non-small Cell Lung Cancer
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Conclusion The change of mtDNA content may play an important role in NSCLC. DOI: 10.3779/j.issn.1009-3419.2011.02.07 (Source: Chinese Journal of Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 4:00:00 am
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Lung Cancer - news item 138 of 144
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A Randomized study on the Effects of Paclitaxel Liposme and Cisplatin Induction Chemotherapy Followed Concurrent Chemoradiotherapy and Sequential Radiotherapy on Locally Advanced Non-small Cell Lung Cancer Patients
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Conclusion The recent effects of induction chemotherapy followed by concurrent chemoradiotherapy group were better than sequential radiotherapy group on locally advanced NSCLC and there was no significant difference in side effects between the two groups. DOI: 10.3779/j.issn.1009-3419.2011.02.06 (Source: Chinese Journal of Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 4:00:00 am
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Lung Cancer - news item 139 of 144
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Correlation between Chlamydia Pneumoniae IgG Positive in Lung Cancer Patients and Cytokines Related to Radiation-induced Pulmonary Lesion
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Conclusion Cpn IgG positive in lung cancer patients influenced levels of IL-1β, SP-A, TGF-β during chest radiotherapy. This might aggravate radiation-induced pulmonary lesion.DOI: 10.3779/j.issn.1009-3419.2011.02.05 (Source: Chinese Journal of Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 4:00:00 am
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Lung Cancer - news item 140 of 144
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Comparison of EGFR Mutation Status in Paired Pre- and Post-chemotherapy Serum for Advanced Pulmonary Adenocarcinoma
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Conclusion Chemotherapy may have influence on serum EGFR mutation status in advanced adenocacinoma patients. DOI: 10.3779/j.issn.1009-3419.2011.02.04 (Source: Chinese Journal of Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 4:00:00 am
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Lung Cancer - news item 141 of 144
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Estimates of Lung Cancer Mortality at the Province Level in China
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Conclusion The models for lung cancer mortality at the province level have been established and the data will provide valuable scientific reference for describing the epidemic of lung cancer as well as estimating other site-specific cancer mortality in China. DOI: 10.3779/j.issn.1009-3419.2011.02.03 (Source: Chinese Journal of Lung Cancer) MedWorm Message: Watch...
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 4:00:00 am
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Lung Cancer - news item 142 of 144
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Descriptive Study on the Epidemiology of Lung Cancer in Coal-producing Area in Eastern Yunnan, China
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Conclusion In Xuanwei country of China, lung cancer was associated with exposure to smoky coal emissions and family susceptibility. Smoking, coking and mining were not the major risk factors lead to lung cancer for women. DOI: 10.3779/j.issn.1009-3419.2011.02.02 (Source: Chinese Journal of Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 4:00:00 am
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Lung Cancer - news item 143 of 144
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Long-term Survival of Personalized Surgical Treatment of Locally Advanced Non-small Cell Lung Cancer Based on Molecular Staging
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Conclusion (1) Micrometastasis was existed in peripheral blood of patients with lung cancer, which can not be detected with conventional methods. (2) Detecting of CK19 mRNA expression in peripheral blood in lung cancer patients can be used for diagnosis of micrometastasis of lung cancer and “molecular staging†and “molecular P-TNM...
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 4:00:00 am
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Lung Cancer - news item 144 of 144
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Establishment of A Novel Chinese Human Lung Adenocarcinoma Cell Line CPA-Yang3 and Its Real Bone Metastasis Clone CPA-Yang3BM in Immunodeficient Mice
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Conclusion Tne characteristics of novel strain CPAYang3 is a highly metastasis cell line of Chinese lung adenocarcinoma and CPA-Yang3BM is a real bone-seeking clone. DOI: 10.3779/j.issn.1009-3419.2011.02.01 (Source: Chinese Journal of Lung Cancer)
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RSS Source: Med Worm - Lung Cancer Sun, 20 Feb 2011 4:00:00 am
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