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Thu, 15 May 2008 at 20:22:11


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Multiple Sclerosis - news item 1 of 49
A new eae model of brain demyelination induced by intracerebroventricular pertussis toxin.
Related Articles A new EAE model of brain demyelination induced by intracerebroventricular pertussis toxin. Biochem Biophys Res Commun. 2008 May 23;370(1):16-21 Authors: Zhao CB, Coons SW, Cui M, Shi FD, Vollmer TL, Ma CY, Kuniyoshi SM, Shi J Experimental autoimmune encephalomyelitis (EAE) is a primary animal model of multiple sclerosis (...
RSS Source:   Med Worm - Multiple Sclerosis Wed, 14 May 2008 12:01:20 am
Multiple Sclerosis - news item 2 of 49
Uk lawmakers to debate limits of embryo research
Parliament on Monday will debate legislation allowing human-animal embryo research that scientists say could help treat conditions like Parkinson's or multiple sclerosis but that opponents say is unethical. Reuters Health Information (Source: Medscape Business of Medicine Headlines)
RSS Source:   Med Worm - Multiple Sclerosis Tue, 13 May 2008 5:01:20 pm
Multiple Sclerosis - news item 3 of 49
Ms can affect children's iq, thinking skills
Multiple sclerosis (MS) typically starts in young adulthood, but about five percent of cases start in childhood or the teen years. Children with MS are at risk to exhibit low IQ scores and problems with memory, attention and other thinking skills, according to a study published in the May 13,...
RSS Source:   Med Worm - Multiple Sclerosis Tue, 13 May 2008 8:00:00 am
Multiple Sclerosis - news item 4 of 49
Childhood ms affects iq, thinking skills
When multiple sclerosis strikes in childhood or during teenage years, victims tend to have cognitive and language difficulties. (Source: Medical Headlines From Ivanhoe.com)
RSS Source:   Med Worm - Multiple Sclerosis Tue, 13 May 2008 5:00:00 am
Multiple Sclerosis - news item 5 of 49
Delayed infusion reactions during natalizumab therapy for ms
In this article, the authors report their experience with natalizumab, with a focus on the types and frequency of acute and delayed infusion reactions. They note that allergic reactions and acute infusion reactions typically occur during or shortly after infusion, with a peak at the second infusion; delayed infusion reactions...
RSS Source:   Med Worm - Multiple Sclerosis Tue, 13 May 2008 12:00:00 am
Multiple Sclerosis - news item 6 of 49
Mental impairment common in children with ms
NEW YORK (Reuters Health) - Low IQ scores and cognitive problems (problems related to thinking and reasoning) are common in children and adolescents with multiple sclerosis (MS), according to an Italian study reported in the journal Neurology. (Source: Reuters: Health)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 9:57:11 pm
Multiple Sclerosis - news item 7 of 49
Pediatric ms linked to cognitive impairment
FLORENCE, Italy -- Multiple sclerosis in childhood and adolescence, a relatively rare form of the disease, is associated with impaired cognitive function and low IQ, said investigators here. (Source: MedPage Today Pediatrics)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 9:32:07 pm
Multiple Sclerosis - news item 8 of 49
Pediatric ms affects thinking, memory
Multiple sclerosis (MS) that strikes during childhood may disrupt a key phase of brain development and appears to have a profound negative impact on a child's ability to think and pay attention. (Source: WebMD Health)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 5:00:00 am
Multiple Sclerosis - news item 9 of 49
Correspondence: differential diagnosis between acute disseminated encephalomyelitis and multiple sclerosis during the first episode--reply
(Source: Archives of Neurology)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 10 of 49
Correspondence: differential diagnosis between acute disseminated encephalomyelitis and multiple sclerosis during the first episode
(Source: Archives of Neurology)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 11 of 49
Correspondence: monophasic acute, recurrent, and multiphasic disseminated encephalomyelitis and multiple sclerosis--reply
(Source: Archives of Neurology)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 12 of 49
Correspondence: monophasic acute, recurrent, and multiphasic disseminated encephalomyelitis and multiple sclerosis
(Source: Archives of Neurology)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 13 of 49
Correspondence: multiple sclerosis and recurrent disseminated encephalomyelitis are different diseases--reply
(Source: Archives of Neurology)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 14 of 49
Correspondence: multiple sclerosis and recurrent disseminated encephalomyelitis are different diseases
(Source: Archives of Neurology)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 15 of 49
Research letters: atorvastatin does not alter interferon beta-induced changes of serum matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 in patients with multiple sclerosis
(Source: Archives of Neurology)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 16 of 49
Observation: allergic and nonallergic delayed infusion reactions during natalizumab therapy
Background  The monoclonal antibody natalizumab is a novel therapeutic option in the treatment of relapsing forms of multiple sclerosis. In general, therapy with natalizumab is well tolerated. Allergic reactions and acute infusion reactions typically occur during or shortly after infusion, with a peak at the second infusion. Delayed infusion reactions...
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 17 of 49
Original contribution: increased osteopontin levels in the cerebrospinal fluid of patients with multiple sclerosis
Objective  To determine cerebrospinal fluid levels of osteopontin (OPN), a proinflammatory cytokine that was found to be overexpressed in multiple sclerosis lesions and increased in plasma during relapses and in secondary progressive multiple sclerosis. Design  Case series. Osteopontin, interleukin 12p40 (IL-12p40), IL-10, and matrix metalloproteinase 9 were measured by enzyme-linked...
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 18 of 49
Cooling via one hand improves physical performance in heat-sensitive individuals with multiple sclerosis: a preliminary study.
Background: Many individuals afflicted with multiple sclerosis (MS), experience a transient worsening of symptoms when body temperature increases due to ambient conditions or physical activity. Resulting symptom exacerbations can limit performance. We hypothesized that extraction of heat from the body through the subcutaneous retia venosa that underlie the palmar surfaces...
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 19 of 49
[letters] coexistence of spondyloarthropathy and multiple sclerosis: a series of 21 cases
(Source: Annals of the Rheumatic Diseases)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 20 of 49
Cognitive and psychosocial features of childhood and juvenile ms
Objective: To assess the impact of multiple sclerosis (MS) on cognitive and psychosocial functioning in childhood and juvenile cases. Methods: We used an extensive neuropsychological battery assessing IQ, memory, attention/concentration, executive functions, and language. Fatigue and depression were also measured. An interview on school and daily living activities was obtained...
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 4:00:00 am
Multiple Sclerosis - news item 21 of 49
Prozac may benefit patients with multiple sclerosis
Amsterdam - Prozac can delay the symptoms of multiple sclerosis (MS), according to a study by Dutch researchers from (Source: Monsters and Critics Health News)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 12 May 2008 3:07:15 am
Multiple Sclerosis - news item 22 of 49
Il-21 and tgf-β are required for differentiation of human th17 cells
IL-21 and TGF-β are required for differentiation of human TH17 cells Nature advance online publication 11 May 2008. doi:10.1038/nature07021 Authors: Li Yang, David E. Anderson, Clare Baecher-Allan, William D. Hastings, Estelle Bettelli, Mohamed Oukka, Vijay K. Kuchroo & David A. Hafler The recent discovery of CD4+ T cells characterized by...
RSS Source:   Med Worm - Multiple Sclerosis Sun, 11 May 2008 4:00:00 am
Multiple Sclerosis - news item 23 of 49
Comparison of disability and quality of life measures in patients with long-term psychotic disorders and patients with multiple sclerosis: an application of the who disability assessment schedule ii and who quality of life-bref.
Page: 141DOI: 10.1097/MRR.0b013e32830150e6Authors: Chopra, Prem a b; Herrman, Helen a; Kennedy, Genevieve b (Source: International Journal of Rehabilitation Research)
RSS Source:   Med Worm - Multiple Sclerosis Fri, 9 May 2008 11:47:57 pm
Multiple Sclerosis - news item 24 of 49
Pharmacogenomics of the response to ifn-β in multiple sclerosis: ramifications from the first genome-wide screen
Pharmacogenomics , May 2008, Vol. 9, No. 5, Pages 639-645. Evaluation of: Byun E, Caillier SJ, Montalban X et al.: Genome-wide pharmacogenomic analysis of the response to interferon-β therapy in multiple sclerosis. Arch. Neurol. 65(3) 337–344 (2008). Specifically, IFN-β is the most widely used disease-modifying ... (Source: Future Medicine: Pharmacogenomics)
RSS Source:   Med Worm - Multiple Sclerosis Fri, 9 May 2008 10:22:34 am
Multiple Sclerosis - news item 25 of 49
High-dose immunosuppressive therapy with autologous hematopoietic stem cell transplantation as a treatment option in multiple sclerosis.
Related Articles High-dose immunosuppressive therapy with autologous hematopoietic stem cell transplantation as a treatment option in multiple sclerosis. Exp Hematol. 2008 May 9; Authors: Shevchenko YL, Novik AA, Kuznetsov AN, Afanasiev BV, Lisukov IA, Kozlov VA, Rykavicin OA, Ionova TI, Melnichenko VY, Fedorenko DA, Kulagin AD, Shamanski SV, Ivanov RA,...
RSS Source:   Med Worm - Multiple Sclerosis Fri, 9 May 2008 4:00:00 am
Multiple Sclerosis - news item 26 of 49
Hla-dr2 and white matter lesion distribution in ms
Journal of Neuroimaging, Volume 0, Issue 0, Page ???, OnlineEarly Articles. ABSTRACT  Human leukocyte antigen DR2 (HLA-DR2) is a well-established genetic risk factor for multiple sclerosis (MS). However, it is still unknown whether this factor is associated with a specific disease phenotype, and in particular, to a regional ... (Source: Journal of...
RSS Source:   Med Worm - Multiple Sclerosis Thu, 8 May 2008 6:32:11 pm
Multiple Sclerosis - news item 27 of 49
Pathogenesis of autoimmune diseases: antibodies against transglutaminase, peptidylarginine deiminase and protein-bound citrulline in primary sjögren’s syndrome, multiple sclerosis and alzheimer’s disease
Scandinavian Journal of Immunology, Volume 67, Issue 6, Page 626-631, June 2008. AbstractCoeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific residues of gliadins have been identified. A similar situation is seen in ... (Source: Scandinavian Journal...
RSS Source:   Med Worm - Multiple Sclerosis Thu, 8 May 2008 2:56:08 pm
Multiple Sclerosis - news item 28 of 49
Smoke exposure increases the risk for multiple sclerosis
European Journal of Neurology, Volume 15, Issue 6, Page 579-583, June 2008. Purpose and methods: To estimate the effect of exposure to smoking on the risk for multiple sclerosis (MS), we analyzed nicotine metabolite (cotinine) levels in biobank samples from 109 MS cases and 218 matched referents.Results: Elevated cotinine levels, ... (Source: European...
RSS Source:   Med Worm - Multiple Sclerosis Thu, 8 May 2008 2:10:59 pm
Multiple Sclerosis - news item 29 of 49
Activity, tolerability and efficacy of levetiracetam on cerebellar symptoms in multiple sclerosis patients: a pilot kinematic study
European Journal of Neurology, Volume 15, Issue 6, Page 619-626, June 2008. Background and purpose: The aim of this study was to evaluate the activity measured by kinematic analysis, tolerability and efficacy of levetiracetam (LEV) in multiple sclerosis (MS) patients affected by cerebellar symptoms, in a randomized single-blind, ... (Source: European Journal...
RSS Source:   Med Worm - Multiple Sclerosis Thu, 8 May 2008 2:10:09 pm
Multiple Sclerosis - news item 30 of 49
Gelsolin concentration in cerebrospinal fluid from patients with multiple sclerosis and other neurological disorders
European Journal of Neurology, Volume 15, Issue 6, Page 584-588, June 2008. Background: Gelsolin is a highly conserved intracellular actin-binding protein with an extracellular isoform, plasma gelsolin, for which there is not yet a clearly defined function. Materials and methods: In this study, we determined gelsolin ... (Source: European Journal of Neurology)
RSS Source:   Med Worm - Multiple Sclerosis Thu, 8 May 2008 2:09:44 pm
Multiple Sclerosis - news item 31 of 49
Marijuana called effective treatment for neuropathic pain
A new study finds that patients given mild doses of marijuana can experience relief from neuropathic pain -- often related to spinal-cord injuries, multiple sclerosis, and other never injuries -- without becoming intoxicated. (Source: Alcohol, Tobacco and Other Drugs News)
RSS Source:   Med Worm - Multiple Sclerosis Wed, 7 May 2008 3:27:13 pm
Multiple Sclerosis - news item 32 of 49
The immunogenetics of multiple sclerosis
Abstract  The discoveries in the 1970s of strong associations between various diseases and certain human leukocyte antigen (HLA) factors were a revolution within genetic epidemiology in the last century by demonstrating for the first time how genetic markers can help unravel the genetics of disorders with complex genetic backgrounds. HLA controls...
RSS Source:   Med Worm - Multiple Sclerosis Wed, 7 May 2008 2:41:42 pm
Multiple Sclerosis - news item 33 of 49
Pupillary function in early multiple sclerosis
Abstract  Autonomic pupillary function was assessed with pupillometry in 95 mildly or moderately disabled patients with multiple sclerosis (MS) and 81 healthy subjects. The parasympathetic pupillary function was measured as initial diameter (mm), time to minimum diameter (seconds), reflex amplitude (mm), relative reflex amplitude (%), and maximal constriction velocity (mm/seconds). To reflect...
RSS Source:   Med Worm - Multiple Sclerosis Wed, 7 May 2008 2:38:47 pm
Multiple Sclerosis - news item 34 of 49
Mr. lube canada supports the multiple sclerosis society of canada and ms awareness month through its founder's day campaign
On Saturday, May 10th, 2008 Mr. Lube Canada will be supporting the Multiple Sclerosis (MS) Society of Canada and MS Awareness Month by donating $5 from every oil change purchase at Mr. Lube locations across the country. Canada has one of the highest rates of MS in the world and...
RSS Source:   Med Worm - Multiple Sclerosis Wed, 7 May 2008 12:00:00 pm
Multiple Sclerosis - news item 35 of 49
Multiple sclerosis, a communication breakdown - research profile from the canadian institutes of health research (cihr)
Multiple sclerosis (MS) is, essentially, a failure to communicate. In a person with MS, the immune system has run amok, destroying the protective myelin coat that surrounds nerve cells. Without this myelin, messages cannot travel between the brain and the body as quickly as they can in a healthy person,...
RSS Source:   Med Worm - Multiple Sclerosis Wed, 7 May 2008 10:00:00 am
Multiple Sclerosis - news item 36 of 49
Depression drug for multiple sclerosis
A drug prescribed to treat depression could be beneficial to those with multiple sclerosis (MS). (Source: Medical Headlines From Ivanhoe.com)
RSS Source:   Med Worm - Multiple Sclerosis Wed, 7 May 2008 5:00:00 am
Multiple Sclerosis - news item 37 of 49
Serum and cerebrospinal fluid uric acid levels in multiple sclerosis patients.
Related Articles Serum and cerebrospinal fluid uric acid levels in multiple sclerosis patients. Clin Neurol Neurosurg. 2008 May 7; Authors: Zamani A, Rezaei A, Khaeir F, Hooper DC PMID: 18471958 [PubMed - as supplied by publisher] (Source: Clinical Neurology and Neurosurgery)
RSS Source:   Med Worm - Multiple Sclerosis Wed, 7 May 2008 4:00:00 am
Multiple Sclerosis - news item 38 of 49
Simvastatin inhibits il-17 secretion by targeting multiple il-17-regulatory cytokines and by inhibiting the expression of il-17 transcription factor rorc in cd4+ lymphocytes.
Simvastatin Inhibits IL-17 Secretion by Targeting Multiple IL-17-Regulatory Cytokines and by Inhibiting the Expression of IL-17 Transcription Factor RORC in CD4+ Lymphocytes. J Immunol. 2008 May 15;180(10):6988-96 Authors: Zhang X, Jin J, Peng X, Ramgolam VS, Markovic-Plese S Statins, extensively used as cholesterol-lowering agents, have recently been identified as immunomodulatory...
RSS Source:   Med Worm - Multiple Sclerosis Tue, 6 May 2008 7:55:09 pm
Multiple Sclerosis - news item 39 of 49
Early anisotropy changes in the corpus callosum of patients with optic neuritis
Abstract Introduction  Optic neuritis (ON) and any other early manifestation of multiple sclerosis (MS) are referred to as clinically isolated syndrome (CIS) as long as MS is suspected. In this prospective study we aimed to determine whether diffusion tensor imaging (DTI) could quantify structural changes in patients with early MS. Methods  A...
RSS Source:   Med Worm - Multiple Sclerosis Tue, 6 May 2008 6:58:08 pm
Multiple Sclerosis - news item 40 of 49
Bone marrow treatments restore nerves, expert says
BETHESDA, Maryland (Reuters) - An experiment that went wrong may provide a new way to treat multiple sclerosis, a Canadian researcher said on Tuesday. (Source: Reuters: Health)
RSS Source:   Med Worm - Multiple Sclerosis Tue, 6 May 2008 6:37:06 pm
Multiple Sclerosis - news item 41 of 49
Oral prednisone taper following intravenous steroids fails to improve disability or recovery from relapses in multiple sclerosis
European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. Background: A short course of intravenous methylprednisolone (IVMP) followed by oral prednisone taper (OPT) is often used for the treatment of relapses in multiple sclerosis (MS). We examined the effect of IVMP plus OPT compared with IVMP only on ... (Source:...
RSS Source:   Med Worm - Multiple Sclerosis Tue, 6 May 2008 6:19:52 pm
Multiple Sclerosis - news item 42 of 49
Is there any evidence for the use of vitamin b for the treatment of fatigue in patients with multiple sclerosis?
We searched the NLH Neurological Conditions Specialist Library and the TRIP and Medline databases but found little robust information on the use of vitamin B to treat fatigue in patients with multiple sclerosis. In fact, we found just one study examining the use of vitamin B12 as part of a...
RSS Source:   Med Worm - Multiple Sclerosis Tue, 6 May 2008 5:08:14 pm
Multiple Sclerosis - news item 43 of 49
Is there evidence to support the use of the herbal supplement kalawalla in patients with ms?
We could find no evidence to support the use of kalawalla. The Multiple Sclerosis Trust has a factsheet on kalawalla [1] and this reports:"Kalawalla is the brand name of an herbal supplement derived from a type of fern native to Central and South America. (Source: NLH Question Answering Service)
RSS Source:   Med Worm - Multiple Sclerosis Tue, 6 May 2008 3:48:35 pm
Multiple Sclerosis - news item 44 of 49
Social support as a predictor of perceived health status in patients with multiple sclerosis.
Related Articles Social support as a predictor of perceived health status in patients with multiple sclerosis. Patient Educ Couns. 2008 May 6; Authors: Krokavcova M, van Dijk JP, Nagyova I, Rosenberger J, Gavelova M, Middel B, Gdovinova Z, Groothoff JW OBJECTIVE: The main aim of this study was to investigate...
RSS Source:   Med Worm - Multiple Sclerosis Tue, 6 May 2008 4:00:00 am
Multiple Sclerosis - news item 45 of 49
Rituximab in a patient with multiple sclerosis – effect on b cells, plasma cells and intrathecal igg synthesis
Acta Neurologica Scandinavica, Volume 117, Issue 6, Page 399-403, June 2008. Petereit HF, Moeller-Hartmann W, Reske D, Rubbert A. Rituximab in a patient with multiple sclerosis – effect on B cells, plasma cells and intrathecal IgG synthesis.Acta Neurol Scand 2008: 117: 399–403.© 2007 The Authors Journal compilation © 2007 ... (Source:...
RSS Source:   Med Worm - Multiple Sclerosis Tue, 6 May 2008 1:52:01 am
Multiple Sclerosis - news item 46 of 49
Fluoxetine may retard progression of ms
Dutch researchers have evidence that the antidepressant fluoxetine can reduce formation of new enhancing lesions in patients with multiple sclerosis (MS). Reuters Health Information (Source: Medscape Pharmacist Headlines)
RSS Source:   Med Worm - Multiple Sclerosis Mon, 5 May 2008 3:25:27 pm
Multiple Sclerosis - news item 47 of 49
Multiple sclerosis activity may be affected by prozac
A new study published in the Journal ofNeurology Neurosurgery and Psychiatry finds that Prozac, acommonly prescribed antidepressant, may be an agent in slowingdown the disease process of the relapsing remitting form of multiplesclerosis (MS).Multiple sclerosis is an autoimmune disease where the immune systemattacks the central nervous system. In the relapsing...
RSS Source:   Med Worm - Multiple Sclerosis Sat, 3 May 2008 7:00:00 am
Multiple Sclerosis - news item 48 of 49
Currents
Currents: Therapeutic targets of multiple sclerosis | Screen for extracellular protein interactions | Cracking combinatorial codes in embryonic stem cells | NMR metabonomic profiling of bipolar disorder | Evaluating the core proteome of bacteria | Correlating proteomics and mRNA microarray data | Porous gold protein arrays and MS | Top-down proteotyping of human leukocytes (Source: Journal of...
RSS Source:   Med Worm - Multiple Sclerosis Fri, 2 May 2008 2:00:00 pm
Multiple Sclerosis - news item 49 of 49
Multiple sclerosis awareness month: ms society reflects on 60 years of progress, canada
Since 1948, the Multiple Sclerosis Society of Canada has led Canada to become one of the world's premier destinations for MS research and has improved hundreds of thousands lives through client care. These are just two reflections to consider during a May, MS Awareness Month. (Source: Multiple Sclerosis News From...
RSS Source:   Med Worm - Multiple Sclerosis Fri, 2 May 2008 10:00:00 am