Osteoporosis - news item 1 of 136
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Coral reef bacteria found to protect bone health, fight cancer
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(NaturalNews) Scientists from the University of Florida (UF) have identified a substance in the bacterium of some varieties of coral reef that helps heal injured and deteriorating bones, as well as prevent bone loss and degradation. Published in the journal ACS Medicinal Chemistry Letters, the findings reveal that largazole, the...
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RSS Source: Med Worm - Osteoporosis Mon, 7 Mar 2011 6:00:00 am
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Osteoporosis - news item 2 of 136
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Personal Health: Revisiting Bone Drugs and Femur Fractures
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A thorough assessment is needed before bisphosphonates are prescribed. (Source: NYT Health)
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RSS Source: Med Worm - Osteoporosis Sun, 6 Mar 2011 10:45:17 pm
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Osteoporosis - news item 3 of 136
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Lactose intolerance: an unnecessary risk for low bone density.
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Authors: Savaiano D The potential for lactose intolerance causes 25-50 million Americans and an unknown number of people around the world to avoid milk. Milk avoidance is a significant risk factor for low bone density. Individuals who avoid milk, due to intolerance or learned aversion, consume significantly less calcium and...
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RSS Source: Med Worm - Osteoporosis Sun, 6 Mar 2011 12:45:03 pm
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Osteoporosis - news item 4 of 136
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Gene responsible for severe osteoporosis disorder discovered
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Scientists have identified a single mutated gene that causes Hajdu-Cheney syndrome, a disorder of the bones causing progressive bone loss and osteoporosis. (Source: ScienceDaily Headlines)
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RSS Source: Med Worm - Osteoporosis Sun, 6 Mar 2011 4:00:00 am
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Osteoporosis - news item 5 of 136
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Don't miss March 7 pre-registration deadline for Valencia meetings
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(International Osteoporosis Foundation) March 7 is the pre-registration deadline for the most important European bone meetings of the year, to be held in Valencia, Spain. The European Congress on Osteoporosis & Osteoarthritis will be held in Valencia's award-winning congress center from March 23-26, 2011. Participants are eligible for 30 continuing...
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RSS Source: Med Worm - Osteoporosis Fri, 4 Mar 2011 4:00:00 am
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Osteoporosis - news item 6 of 136
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Risk reduction of falls and fractures, reduction of back pain and safety in elderly high risk patients receiving combined therapy with alfacalcidol and alendronate: a prospective study.
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Authors: Schacht E, Ringe JD Efficacy and safety of a new combination package containing 4 or 12 self-explanatory one-week blisters, each with one tablet of 70 mg alendronate (CAS 260055-05-8) and 7 capsules of 1 microg alfacalcidol (CAS 41294-56-8) (Tevabone) on muscle power, muscle function, balance and back pain was...
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RSS Source: Med Worm - Osteoporosis Fri, 4 Mar 2011 12:00:08 am
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Osteoporosis - news item 7 of 136
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Tomatoes help combat heart disease and cancer - and are even more potent when cooked
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Eating tomatoes can help reduce the risk of cancer, osteoporosis and cardiovascular disease, scientists have revealed - and cooking the veg can increase its effect. (Source: the Mail online | Health)
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RSS Source: Med Worm - Osteoporosis Thu, 3 Mar 2011 8:02:43 am
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Osteoporosis - news item 8 of 136
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Osteoporosis Prevention
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This article discusses dietary modifications, exercise, and other preventive measures. Current Opinion in Rheumatology (Source: Medscape Today Headlines)
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RSS Source: Med Worm - Osteoporosis Thu, 3 Mar 2011 3:00:00 am
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Osteoporosis - news item 9 of 136
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Will A Bike Ride a Day Keep the Doctor Away?: Researcher Says Portland’s Bike Paths Will Cut Its Health Costs
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This study appeared in a special issue of the Journal of Physical Activity and Health, funded by the Robert Wood Johnson Foundation through its national program Active Living Research. (Source: RWJF News Digest - Childhood Obesity)
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RSS Source: Med Worm - Osteoporosis Wed, 2 Mar 2011 11:00:00 pm
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Osteoporosis - news item 10 of 136
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Osteoporosis underdiagnosed in people with intellectual disabilities
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Individuals with intellectual disabilities often have several risk factors for osteoporosis but do not receive adequate screening for the disease, UK researchers report. (Source: MedWire News - Bone Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!...
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RSS Source: Med Worm - Osteoporosis Wed, 2 Mar 2011 10:10:34 pm
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Osteoporosis - news item 11 of 136
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Medical Minute: Osteoporosis In Men
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WBZ's Dr. Murray Feingold says women aren't the only ones at risk. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)
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RSS Source: Med Worm - Osteoporosis Wed, 2 Mar 2011 5:31:12 pm
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Osteoporosis - news item 12 of 136
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Tomatoes, The New Superfood
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Eating more tomatoes and tomato products can make people healthier and decrease the risk of conditions such as cancer, osteoporosis and cardiovascular disease, according to a review article the American Journal of Lifestyle Medicine, (published by SAGE). Of all the non-starchy vegetables, Americans eat more tomatoes and tomato products than...
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RSS Source: Med Worm - Osteoporosis Wed, 2 Mar 2011 8:00:00 am
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Osteoporosis - news item 13 of 136
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High fracture probability with FRAX® usually indicates densitometric osteoporosis: implications for clinical practice
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Conclusions A FRAX designation of high risk of fracture is usually associated with a densitometric diagnosis of osteoporosis. Content Type Journal ArticlePages 1-7DOI 10.1007/s00198-011-1592-3Authors W. D. Leslie, University of Manitoba, Winnipeg, CanadaS. R. Majumdar, University of Alberta, Edmonton, CanadaL. M. Lix, University of Saskatchewan, Saskatoon, CanadaH. Johansson, Gothenburg, SwedenA. Oden,...
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RSS Source: Med Worm - Osteoporosis Wed, 2 Mar 2011 6:46:19 am
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Osteoporosis - news item 14 of 136
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Premenopausal women with idiopathic low-trauma fractures and/or low bone mineral density
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Conclusions Higher serum TRAP5b and PTH suggest that increased bone turnover, possibly related to subclinical secondary hyperparathyroidism could contribute to the pathogenesis of IOP. The absence of differences between women with fractures and those with very low BMD indicates that this distinction may not be clinically useful to categorize young...
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RSS Source: Med Worm - Osteoporosis Wed, 2 Mar 2011 6:46:18 am
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Osteoporosis - news item 15 of 136
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Vertebral fracture efficacy during risedronate therapy in patients using proton pump inhibitors
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Conclusions Risedronate significantly reduced the risk of new vertebral fractures compared with placebo, regardless of PPI concomitant use. Content Type Journal ArticlePages 1-8DOI 10.1007/s00198-011-1574-5Authors C. Roux, Department of Rheumatology, AP-HP Cochin Hospital, Paris Descartes University, 27 rue Faubourg Saint Jacques, Paris, 75014 FranceJ. L. Goldstein, Department of Medicine, University of...
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RSS Source: Med Worm - Osteoporosis Wed, 2 Mar 2011 6:46:17 am
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Osteoporosis - news item 16 of 136
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Advances in Glucocorticoid-Induced Osteoporosis
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Abstract Glucocorticoid-induced osteoporosis (GIOP) is one of the most important side effects of glucocorticoid use, as it leads to an increased risk of fractures. Recently, many published studies have focused on the cellular and molecular mechanisms of bone metabolism, the pathophysiology of GIOP, and the intervention options to prevent GIOP....
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RSS Source: Med Worm - Osteoporosis Wed, 2 Mar 2011 6:44:30 am
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Osteoporosis - news item 17 of 136
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Protective effects of fish intake and interactive effects of long-chain polyunsaturated fatty acid intakes on hip bone mineral density in older adults: the Framingham Osteoporosis Study.
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CONCLUSIONS: Fish consumption may protect against bone loss. The protective effects of a high AA intake may be dependent on the amount of EPA+DHA intake. PMID: 21367955 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
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RSS Source: Med Worm - Osteoporosis Tue, 1 Mar 2011 11:00:00 pm
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Osteoporosis - news item 18 of 136
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The Waning of Teriparatide Effect on Bone Formation Markers in Postmenopausal Osteoporosis Is Associated with Increasing Serum Levels of DKK1.
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Conclusion: Long-term (>12 months) treatment with TPD is associated with an increase in serum levels of DKK1 that might be associated with the appearance of declining effect on bone formation markers. PMID: 21367927 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
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RSS Source: Med Worm - Osteoporosis Tue, 1 Mar 2011 11:00:00 pm
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Osteoporosis - news item 19 of 136
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Diagnosis and Treatment of Subclinical Hypercortisolism.
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Conclusions: SH is suggested to be associated with some chronic complications of overt cortisol excess. Recovery from this condition seems to improve these complications. However, a large, prospective, randomized study is needed to confirm this hypothesis and to establish the best diagnostic approach to identify patients with adrenal incidentalomas who...
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RSS Source: Med Worm - Osteoporosis Tue, 1 Mar 2011 11:00:00 pm
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Osteoporosis - news item 20 of 136
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Non-pharmacological management of osteoporosis: a consensus of the Belgian Bone Club
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Abstract This consensus article reviews the various aspects of the non-pharmacological management of osteoporosis, including the effects of nutriments, physical exercise, lifestyle, fall prevention, and hip protectors. Vertebroplasty is also briefly reviewed. Non-pharmacological management of osteoporosis is a broad concept. It must be viewed as an essential part of the...
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RSS Source: Med Worm - Osteoporosis Tue, 1 Mar 2011 6:07:49 am
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Osteoporosis - news item 21 of 136
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[Ectopic ACTH-secreting neuroendocrine tumor.]
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Authors: Szabó A, Igaz P, Kiss R, Lakatos G, Varga I, Rácz K The authors report a case of an ectopic ACTH-syndrome that resulted in severe hypercortisolism, hypokalemia, diabetes mellitus and osteoporosis. The ACTH-secreting tumor tissue was localized in the lung. The tumor was removed by segmentectomy and histological evaluation...
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RSS Source: Med Worm - Osteoporosis Mon, 28 Feb 2011 11:00:00 pm
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Osteoporosis - news item 22 of 136
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Bet 1
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(Source: Emergency Medicine Journal)
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RSS Source: Med Worm - Osteoporosis Mon, 28 Feb 2011 11:00:00 pm
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Osteoporosis - news item 23 of 136
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Effects of Nutrition and Alcohol Consumption on Bone Loss
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Abstract It is well established that excessive consumption of high-fat diets results in obesity. However, the consequences of obesity on skeletal development, maturation, and remodeling have been the subject of controversy. New studies suggest that the response of the growing skeleton to mechanical loading is impaired and trabecular bone mass...
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RSS Source: Med Worm - Osteoporosis Mon, 28 Feb 2011 3:45:43 pm
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Osteoporosis - news item 24 of 136
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Hematopoietic Cell Regulation of Osteoblast Proliferation and Differentiation
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Abstract The last several decades have revealed numerous interactions between cells of the hematopoietic lineage and osteoblasts (OBs) of the mesenchymal lineage. For example, OBs are important players in the hematopoietic stem cell (HSC) niche and OBs are known to impact osteoclast (OC) development. Thus, although much is known regarding...
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RSS Source: Med Worm - Osteoporosis Mon, 28 Feb 2011 3:45:42 pm
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Osteoporosis - news item 25 of 136
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A Central Role for Hypoxic Signaling in Cartilage, Bone, and Hematopoiesis
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Abstract Hypoxic signaling plays an essential role in maintaining oxygen homeostasis and cell survival. Hypoxia-inducible transcription factors HIF-1 and HIF-2 are central mediators of the cellular response to hypoxia by regulating the expression of genes controlling metabolic adaptation, oxygen delivery, and survival in response to oxygen deprivation. Recent studies have...
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RSS Source: Med Worm - Osteoporosis Mon, 28 Feb 2011 3:45:41 pm
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Osteoporosis - news item 26 of 136
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Health benefits of eating tomatoes emerge
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(SAGE Publications) Eating more tomatoes and tomato products can make people healthier and decrease the risk of conditions such as cancer, osteoporosis and cardiovascular disease, according to a review article the American Journal of Lifestyle Medicine, published by SAGE. (Source: EurekAlert! - Medicine and Health)
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RSS Source: Med Worm - Osteoporosis Mon, 28 Feb 2011 4:00:00 am
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Osteoporosis - news item 27 of 136
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NICE consults on potential new QOF indicators for 2012/13
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Source: NICE Area: News NICE is consulting on a number of potential new indicators for the 2012/13 Quality and Outcomes Framework (QOF); stakeholders are invited to comment by 5.30pm on Monday 28th March 2011 (please see the link below for details). The 29 potential new indicators cover the following domains: ....
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RSS Source: Med Worm - Osteoporosis Sun, 27 Feb 2011 11:00:00 pm
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Osteoporosis - news item 28 of 136
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Associations of total osteocalcin with all-cause and cardiovascular mortality in older men. The Health In Men Study
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Conclusions TOC predicts all-cause and CVD-related mortality in community-dwelling older men. However, the relationship is U shaped with men at both ends of the distribution at increased risk. Further investigation is required to clarify whether the underlying mechanisms involve altered bone turnover or relate specifically to the biological activity of...
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RSS Source: Med Worm - Osteoporosis Sat, 26 Feb 2011 2:18:08 pm
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Osteoporosis - news item 29 of 136
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Pattern of use of DXA scans in men: a cross-sectional, population-based study
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Conclusions DXA was infrequent in this group of elderly men, despite the presence of risk factors for osteoporosis. DXA was also used despite a low fracture risk. There is a need for improved targeting of DXA scans for men at high risk. Content Type Journal ArticlePages 1-9DOI 10.1007/s00198-011-1589-yAuthors M. Frost,...
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RSS Source: Med Worm - Osteoporosis Sat, 26 Feb 2011 2:18:08 pm
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Osteoporosis - news item 30 of 136
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Osteoporotic changes of subchondral trabecular bone in osteoarthritis of the knee: a 3-T MRI study
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Conclusions To more sensitively detect OA changes in subchondral trabecular bone structure, a focus on osteoporotic changes in the lateral joint and the medial-lateral ratio would be useful. Detectability of early OA remains unknown, but based on a strong correlation with the degree of OA progression, trabecular structural analysis of...
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RSS Source: Med Worm - Osteoporosis Sat, 26 Feb 2011 2:18:06 pm
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Osteoporosis - news item 31 of 136
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Pubertal timing and body mass index gain from birth to maturity in relation with femoral neck BMD and distal tibia microstructure in healthy female subjects
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Conclusion BMI gain during childhood is associated with pubertal timing, which in turn, is correlated with several bone traits measured at PBM including FN aBMD, cortical thickness, and volumetric trabecular density of distal tibia. These data complement the reported relationship between childhood BMI gain and hip fracture risk in later...
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RSS Source: Med Worm - Osteoporosis Sat, 26 Feb 2011 2:18:06 pm
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Osteoporosis - news item 32 of 136
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In peripubertal girls, artistic gymnastics improves areal bone mineral density and femoral bone geometry without affecting serum OPG/RANKL levels
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Conclusion GYM is associated not only with an increase in aBMD but also an improvement in bone geometry associated with an increase in bone remodelling. These adaptations seem to be independent of the OPG/RANKL system. Content Type Journal ArticlePages 1-12DOI 10.1007/s00198-011-1541-1Authors L. Maïmoun, Service d’Hormonologie, Hôpital Lapeyronie, CHU Montpellier et...
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RSS Source: Med Worm - Osteoporosis Sat, 26 Feb 2011 2:18:03 pm
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Osteoporosis - news item 33 of 136
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Poor Status Of Post-Fracture Care And Osteoporosis Management In Eastern Europe And Central Asia Of Concern
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The International Osteoporosis Foundation (IOF) has issued a report - 'Eastern European & Central Asian Regional Audit - Epidemiology, Costs & Burden of Osteoporosis in 2010' - revealing the serious problem of osteoporosis in 21 nations in Central Asia and Eastern Europe, including Russia. The report explains how poor post-fracture...
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RSS Source: Med Worm - Osteoporosis Sat, 26 Feb 2011 7:00:00 am
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Osteoporosis - news item 34 of 136
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The Acid, Alkaline Diet: Eating to Protect Bones?
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Some acid/alkaline diet proponents claim that while the body maintains acid/alkaline balance, this comes at significant cost to health. When one eats a steady diet of high acid forming foods, calcium is leached out of bones to maintain the body's pH, leading to osteoporosis and other problems. What's your view? (...
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RSS Source: Med Worm - Osteoporosis Sat, 26 Feb 2011 12:28:59 am
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Osteoporosis - news item 35 of 136
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Director's Comments: NIH MedlinePlus Magazine Winter 2011
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Listen to the NLM Director's Comments on "NIH MedlinePlus Magazine Winter 2011". The transcript is also available. The new edition of NIH MedlinePlus magazine helps you quit smoking and understand osteoporosis †plus the current issue provides information about sickle cell disease, mobile technology, and NLM's 175th anniversary... (Source: What's...
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RSS Source: Med Worm - Osteoporosis Fri, 25 Feb 2011 3:47:52 pm
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Osteoporosis - news item 36 of 136
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Serum 25-hydroxyvitamin D, bone mineral density, and non-vertebral fracture risk in community-dwelling older men: results from Mr. Os, Hong Kong
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Conclusions Vitamin D deficiency was not common in this sample of Chinese men. Higher serum 25OHD level was associated with higher BMD at cross-sectional level. There was no association between serum 25OHD level and bone loss or fracture risk. Content Type Journal ArticlePages 1-10DOI 10.1007/s11657-011-0053-0Authors Ruth Chan, Department of Medicine...
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RSS Source: Med Worm - Osteoporosis Fri, 25 Feb 2011 6:20:55 am
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Osteoporosis - news item 37 of 136
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Prevalence of vertebral fractures in patients with rheumatoid arthritis: revisiting the role of glucocorticoids
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Conclusion Rheumatoid arthritis is a risk factor of VF (OR = 6.5). VFA is a convenient tool for this diagnosis. Presence of VF is inversely related to the use of DMARD and glucocorticoids, enhancing the hypothesis that an appropriate control of the disease may be a protective factor against bone fragility. Content...
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RSS Source: Med Worm - Osteoporosis Fri, 25 Feb 2011 6:20:43 am
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Osteoporosis - news item 38 of 136
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Assessment of health claims in the field of bone: a view of the Group for the Respect of Ethics and Excellence in Science (GREES)
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Conclusion The consensus reached is that the level of health claim may differ according to the surrogate endpoint used and on additional animal studies provided to support the claim. Content Type Journal ArticlePages 1-7DOI 10.1007/s00198-011-1561-xAuthors O. Bruyère, Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, BelgiumR....
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RSS Source: Med Worm - Osteoporosis Fri, 25 Feb 2011 6:20:42 am
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Osteoporosis - news item 39 of 136
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Advancing maternal age is associated with lower bone mineral density in young adult male offspring
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Conclusions In conclusion, our results suggest that advancing maternal age could negatively affect bone mass in young adult men. Content Type Journal ArticlePages 1-8DOI 10.1007/s00198-011-1558-5Authors R. Rudäng, Center for Bone and Arthritis Research at the Sahlgrenska Academy, Institute of Medicine, University of Gothenburg, 413 45 Gothenburg, SwedenD. Mellström, Center for...
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RSS Source: Med Worm - Osteoporosis Fri, 25 Feb 2011 6:20:42 am
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Osteoporosis - news item 40 of 136
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Osteoporosis Drug Linked To Fractures
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(Ivanhoe Newswire) -- An osteoporosis drug designed to improve bone health may be associated with femoral fractures. (Source: Medical Headlines From Ivanhoe.com)
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RSS Source: Med Worm - Osteoporosis Fri, 25 Feb 2011 4:00:00 am
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Osteoporosis - news item 41 of 136
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Nitrates: Cheap Osteoporosis Treatment?
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(Ivanhoe Newswire) -- The same medicines used to treat angina and chronic heart failure, may also help treat osteoporosis. (Source: Medical Headlines From Ivanhoe.com) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Osteoporosis Fri, 25 Feb 2011 4:00:00 am
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Osteoporosis - news item 42 of 136
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[Does osteoporosis lead to reduction the primary stability of cementless hip cups?]
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CONCLUSION: Impaired osseointegration in osteoporotic bone because of increased micromovement is not to be expected in the investigated cementless hip cups as no relevant differences in micromovement were found between normal and osteoporotic bone stock. On the basis of the good clinical results with the Monoblock cup, the upper limit...
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RSS Source: Med Worm - Osteoporosis Thu, 24 Feb 2011 11:00:00 pm
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Osteoporosis - news item 43 of 136
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Quantitative analysis of vertebral bone marrow perfusion using dynamic contrastâ€enhanced MRI: Initial results in osteoporotic patients with acute vertebral fracture
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Conclusion:Perfusion parameters were decreased significantly in normalâ€appearing vBM of patients. Furthermore, significant perfusion alterations were observed in acute osteoporotic vertebral fractures compared to normalâ€appearing vertebrae. J. Magn. Reson. Imaging 2011;33:676†683. © 2011 Wileyâ€Liss, Inc. (Source: Journal of Magnetic Resonance Imaging)
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RSS Source: Med Worm - Osteoporosis Thu, 24 Feb 2011 8:18:04 pm
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Osteoporosis - news item 44 of 136
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Genetic profiling may improve fracture risk prediction
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Genetic profiling could enhance the predictive accuracy of fracture risk assessment and help to identify high-risk individuals for appropriate management of osteoporosis or fracture prevention interventions, according to Australian researchers. (Source: MedWire News - Bone Health)
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RSS Source: Med Worm - Osteoporosis Thu, 24 Feb 2011 7:14:17 pm
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Osteoporosis - news item 45 of 136
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Does Strontium Ranelate Affect Smell or Taste?
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This dietary supplement is commonly used for osteoporosis. Medscape Pharmacists (Source: Medscape Today Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Osteoporosis Thu, 24 Feb 2011 2:24:36 pm
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Osteoporosis - news item 46 of 136
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Hypercalcemia in Pregnancy: A Case of Milk-Alkali Syndrome
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We report a case of a 26-year-old woman in her second trimester of pregnancy who presented with 2 weeks of flank pain, nausea, vomiting, anorexia, headache, and lightheadedness. The history revealed consumption of a large quantity of milk, calcium carbonate antacid, and calcium-containing prenatal vitamins. Her symptoms and hypercalcemia resolved...
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RSS Source: Med Worm - Osteoporosis Thu, 24 Feb 2011 7:02:39 am
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Osteoporosis - news item 47 of 136
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Fasting and postprandial spot urine calcium-to-creatinine ratios do not detect hypercalciuria
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Conclusions The SUCCR is not interchangeable with the 24HUC. The fasting SUCCR systematically underestimates, and the postprandial SUCCR systematically overestimates, 24HUC. The average SUCCR demonstrates low sensitivity and specificity for hypercalciuria. Clinicians must use the 24HUC to diagnose hypercalciuria in postmenopausal women. Content Type Journal ArticlePages 1-10DOI 10.1007/s00198-011-1580-7Authors A. N....
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RSS Source: Med Worm - Osteoporosis Thu, 24 Feb 2011 7:02:02 am
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Osteoporosis - news item 48 of 136
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New laboratory tools in the assessment of bone quality
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Abstract Bone quality is a complex set of intricated and interdependent factors that influence bone strength. A number of methods have emerged to measure bone quality, taking into account the organic or the mineral phase of the bone matrix, in the laboratory. Bone quality is a complex set of different...
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RSS Source: Med Worm - Osteoporosis Thu, 24 Feb 2011 7:02:01 am
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Osteoporosis - news item 49 of 136
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8 special sessions at European Congress on Osteoporosis and Osteoarthritis in Valencia
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(International Osteoporosis Foundation) ECCEO11-IOF (CME accredited) will feature plenary lectures, oral presentations, Meet-the-Professor sessions, satellite symposia and, for the first time, eight special ESCEO-FROMO symposia. (Source: EurekAlert! - Medicine and Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized...
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RSS Source: Med Worm - Osteoporosis Thu, 24 Feb 2011 4:00:00 am
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Osteoporosis - news item 50 of 136
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IOF calls for action following release of Eastern European & Central Asian Regional Audit
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(International Osteoporosis Foundation) An audit report by the International Osteoporosis Foundation consolidates information on the status and burden of osteoporosis in 21 countries of Eastern Europe and Central Asia, including the Russian Federation. The publication includes projections and data for Armenia, Azerbaijan, Belarus, Bulgaria, Czech Republic, Estonia, Georgia, Hungary, Kazakhstan,...
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RSS Source: Med Worm - Osteoporosis Thu, 24 Feb 2011 4:00:00 am
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Osteoporosis - news item 51 of 136
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QCT-based finite element models predict human vertebral strength in vitro significantly better than simulated DEXA
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Conclusions The QCT-based hFE method provides a quantitative and significantly improved prediction of vertebral strength in vitro when compared to simulated DXA. This superior predictive power needs to be verified for loading conditions that simulate even more the in vivo case for human vertebrae. Content Type Journal ArticlePages 1-10DOI 10.1007/s00198-011-1568-3Authors...
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 11:07:42 pm
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Osteoporosis - news item 52 of 136
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Novel oxysterols have proâ€osteogenic and antiâ€adipogenic effects in vitro and induce spinal fusion in vivo
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AbstractStimulation of bone formation by osteoinductive materials is of great clinical importance in spinal fusion surgery, repair of bone fractures, and in the treatment of osteoporosis. We previously reported that specific naturally occurring oxysterols including 20(S)â€hydroxycholesterol (20S) induce the osteogenic differentiation of pluripotent mesenchymal cells, while inhibiting their adipogenic differentiation....
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 11:00:00 pm
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Osteoporosis - news item 53 of 136
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Current and Future Economic Burden of Osteoporosis in New Zealand
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(Source: Applied Health Economics and Health Policy)
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 10:05:01 pm
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Osteoporosis - news item 54 of 136
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Nitroglycerin cream may improve bone density: study
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Could a drug commonly used to ease chest pain in millions of people with angina help prevent bone loss in those with osteoporosis? New research suggests there is reason for hope. (Source: CTV Health)
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 5:14:31 pm
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Osteoporosis - news item 55 of 136
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Bisphosphonate Treatment Can Increase Thigh Bone Breaks
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In curious research, it is found that women who use bone mass loss inhibitors, or bisphosphonates, have a higher incidence of breaking their thigh bones, or femoral shaft, than women who use this defensive medication less. In the primary analysis, researchers found that use of bisphosphonates for five years or...
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 4:00:00 pm
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Osteoporosis - news item 56 of 136
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Osteoporosis drug raises risk of thigh fracture: study
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Older women who take osteoporosis drugs known as bisphosphonates for at least five years are more likely to sustain atypical fractures of the thigh bone, compared to women who take the medications for a shorter period, a study suggests. (Source: CTV Health)
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 3:05:29 pm
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Osteoporosis - news item 57 of 136
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Atypical Fracture Risk with Bone Drugs Quantified (CME/CE)
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(MedPage Today) -- Long-term treatment with bisphosphonates for osteoporosis hikes the chances of atypical femur fractures nearly three-fold, researchers said, but the absolute risk remains very small. (Source: MedPage Today Endocrinology)
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 2:43:02 pm
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Osteoporosis - news item 58 of 136
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Study probes use of nitroglycerin to treat osteoporosis
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Nitroglycerin is often prescribed for patients with a heart condition, but now it's being looked as a possible treatment for osteoporosis. (Source: CTV Health)
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 10:53:40 am
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Osteoporosis - news item 59 of 136
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Nitroglycerin Boosts Bone Density And Bone Strength
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Nitroglycerin is best known as a high explosive or a treatment for angina, but a new study in the February 23rd issue of the Journal of the American Medical Association says it may also be an effective therapy to strengthen bones and treat osteoporosis. "Our findings demonstrate that nitroglycerin ointment,...
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 10:00:00 am
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Osteoporosis - news item 60 of 136
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Health Headlines: Jobs cuts, Allergy tests and Osteoporosis
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Welcome to our daily round-up of health stories making the national news. Don't forget to tell us your views. (Source: HealthcareRepublic Pharmacist News) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 8:34:00 am
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Osteoporosis - news item 61 of 136
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Osteoporosis drugs 'raise the risk of thigh fractures' warn researchers
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Those taking bisphosphonate drugs for five years – the recommended duration to improve bone strength – are at risk of broken legs, the Canadian study found. (Source: the Mail online | Health)
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 6:49:04 am
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Osteoporosis - news item 62 of 136
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Preview of oral presentations at the 1st IOF-ESCEO Pre-Clinical Symposium
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(International Osteoporosis Foundation) This release contains a preview of oral presentations at the new forum for basic and translational bone research: IOF-ESCEO 1st Pre-Clinical Symposium. (Source: EurekAlert! - Medicine and Health)
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 4:00:00 am
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Osteoporosis - news item 63 of 136
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Study links long-term use of osteoporosis drugs to unusual fractures
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Women who take commonly prescribed drugs for osteoporosis known as bisphosphonates for five years or more may be at higher risk of certain kinds of fractures of their thigh bone, a new study has found. (Source: St. Michael's Hospital News and Media)
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RSS Source: Med Worm - Osteoporosis Wed, 23 Feb 2011 12:33:14 am
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Osteoporosis - news item 64 of 136
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The Genetics of Bone Loss: Challenges and Prospects.
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Conclusions: Although recent genome-wide association and candidate gene studies have begun to identify genes that influence BMD, efforts to identify susceptibility genes specific for bone loss have proceeded more slowly. Nevertheless, clues are beginning to emerge on where to look, and as population studies accumulate, there is hope that important...
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RSS Source: Med Worm - Osteoporosis Tue, 22 Feb 2011 11:00:00 pm
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Osteoporosis - news item 65 of 136
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Nitroglycerin May Help Prevent Osteoporosis (CME/CE)
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(MedPage Today) -- An ointment containing nitroglycerin modestly reduced bone loss and increased bone formation in postmenopausal women in a two-year randomized trial -- raising the possibility of a new approach for preventing osteoporosis. (Source: MedPage Today Endocrinology) MedWorm Message: Watch the new MedWorm demo and find out how to...
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RSS Source: Med Worm - Osteoporosis Tue, 22 Feb 2011 8:44:17 pm
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Osteoporosis - news item 66 of 136
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More Unusual, Fewer Usual Breaks with Bone Drugs
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Women who take bone drugs for several years have a slightly increased chance of suffering an unusual type of thigh fracture, according to a large Canadian study.Source: Reuters Health Related MedlinePlus Pages: Fractures, Medicines, Osteoporosis (Source: MedlinePlus Health News)
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RSS Source: Med Worm - Osteoporosis Tue, 22 Feb 2011 8:28:53 pm
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Osteoporosis - news item 67 of 136
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Nitroglycerin Ointment Might Strengthen Bones
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Inexpensive heart drug appears to slow bone loss and build new bone, researchers say Source: HealthDay Related MedlinePlus Pages: Medicines, Osteoporosis (Source: MedlinePlus Health News)
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RSS Source: Med Worm - Osteoporosis Tue, 22 Feb 2011 8:00:00 pm
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Osteoporosis - news item 68 of 136
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The factor-of-risk biomechanical approach predicts hip fracture in men and women: the Framingham Study
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Conclusions Thus, both Φ peak and Φ attenuated predict hip fracture in men and women. These findings suggest additional studies of Φ predicting hip fracture using direct measurements of trochanteric soft tissue. Content Type Journal ArticlePages 1-8DOI 10.1007/s00198-011-1569-2Authors A. B. Dufour, Department of Biostatistics, Boston University School of Public Health,...
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RSS Source: Med Worm - Osteoporosis Tue, 22 Feb 2011 4:08:33 pm
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Osteoporosis - news item 69 of 136
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New Study Shows Taking Oral Bisphosphonates Reduces Colorectal Cancer Risk
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The use of oral bisphosphonates, typically used to treat osteoporosis and bone metastases in breast cancer, has recently been found to reduce breast cancer risk. (Source: Cancer Network)
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RSS Source: Med Worm - Osteoporosis Tue, 22 Feb 2011 2:30:01 pm
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Osteoporosis - news item 70 of 136
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Is Nitroglycerin a Novel and Inexpensive Treatment for Osteoporosis? [Editorial]
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(Source: JAMA) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Osteoporosis Mon, 21 Feb 2011 11:00:00 pm
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Osteoporosis - news item 71 of 136
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Effect of Nitroglycerin Ointment on Bone Density and Strength in Postmenopausal Women: A Randomized Trial [Preliminary Communication]
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Conclusion Among postmenopausal women, nitroglycerin ointment modestly increased BMD and decreased bone resorption. Trial Registration isrctn.org Identifier: ISRCTN94484747 (Source: JAMA)
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RSS Source: Med Worm - Osteoporosis Mon, 21 Feb 2011 11:00:00 pm
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Osteoporosis - news item 72 of 136
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Bisphosphonate Use and the Risk of Subtrochanteric or Femoral Shaft Fractures in Older Women [Original Contribution]
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Conclusion Among older women, treatment with a bisphosphonate for more than 5 years was associated with an increased risk of subtrochanteric or femoral shaft fractures; however, the absolute risk of these fractures is low. (Source: JAMA)
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RSS Source: Med Worm - Osteoporosis Mon, 21 Feb 2011 11:00:00 pm
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Osteoporosis - news item 73 of 136
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Body composition, metabolic syndrome and type 2 diabetes in Klinefelter syndrome
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Conclusion:  Preventable causes of the increased morbidity and mortality, such as osteoporosis, chronic obstructive airway disease or type 2 diabetes should be screened for. Despite the lack of randomised controlled studies, we recommend testosterone treatment in case of increased LH or low serum testosterone or, and weight reduction programmes if...
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RSS Source: Med Worm - Osteoporosis Mon, 21 Feb 2011 11:00:00 pm
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Osteoporosis - news item 74 of 136
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Role of Altered Signal Transduction in Heterotopic Ossification and Fibrodysplasia Ossificans Progressiva
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Abstract Heterotopic ossification is a pathologic condition in which bone tissue is formed outside of the skeleton, within soft tissues of the body. The extraskeletal bone that forms in these disorders is normal; the cellular mechanisms that direct cell fate decisions are dysregulated. Patients with fibrodysplasia ossificans progressiva (FOP), a...
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RSS Source: Med Worm - Osteoporosis Mon, 21 Feb 2011 4:07:25 pm
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Osteoporosis - news item 75 of 136
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Improving Calcium Supplement With The Help OF Crustaceans
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Ben-Gurion University of the Negev (BGU) researchers have developed a unique technology that stabilizes an otherwise unstable form of calcium carbonate. This mineral form provides significantly higher biological absorption and retention rates than other sources presently used as dietary calcium supplements. Calcium is considered to be one of the most...
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RSS Source: Med Worm - Osteoporosis Mon, 21 Feb 2011 8:00:00 am
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Osteoporosis - news item 76 of 136
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Does whole-body vibration with alternative tilting increase bone mineral density and change bone metabolism in senior people ?
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Conclusions: The present study suggested that WBVAT treatment could increase BMD in senior people, particularly in people with OP and women. Changes of bone metabolism following the WBVAT treatment were not observed in most cases. PMID: 21339698 [PubMed - as supplied by publisher] (Source: Aging Clinical and Experimental Research)
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RSS Source: Med Worm - Osteoporosis Sun, 20 Feb 2011 11:00:00 pm
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Osteoporosis - news item 77 of 136
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Algorithms can be used to identify fragility fracture cases in physician-claims databases
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Conclusion Algorithms using PCDs are accurate and reliable for identifying incident fractures associated with osteoporosis-related fracture sites. The identification of these fractures in the community is important for helping to estimate the burden associated with osteoporosis and the utility of programs designed to reduce the rates of fragility fracture. Content...
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RSS Source: Med Worm - Osteoporosis Sat, 19 Feb 2011 6:02:22 am
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Osteoporosis - news item 78 of 136
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Effectiveness of interventions to improve the detection and treatment of osteoporosis in primary care settings: a systematic review and meta-analysis
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This study aims to evaluate the effectiveness of primary care interventions to improve the detection and treatment of osteoporosis. Eight electronic databases and six gray literature sources were searched. Randomized controlled trials, controlled clinical trials, quasi-randomized trials, controlled before†after studies, and interrupted time series written in English or French...
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RSS Source: Med Worm - Osteoporosis Sat, 19 Feb 2011 6:02:22 am
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Osteoporosis - news item 79 of 136
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Erratum to: Effects of calcium-fortified ice cream on markers of bone health
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Content Type Journal ArticlePages 1-1DOI 10.1007/s00198-011-1576-3Authors L. Ferrar, Sheffield NIHR Bone Biomedical Research Unit, University of Sheffield and Sheffield Teaching Hospital Foundation Trust, Centre for Biomedical Research, Herries Road, Sheffield, S5 7AU South Yorkshire UKR. M. van der Hee, Unilever R&D Vlaardingen, Vlaardingen, The NetherlandsM. Berry, Unilever R&D Colworth, Colworth...
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RSS Source: Med Worm - Osteoporosis Sat, 19 Feb 2011 6:02:21 am
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Osteoporosis - news item 80 of 136
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A role for suppressed bone formation favoring catch-up fat in the pathophysiology of catch-up growth after food restriction
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Conclusion CUGFR induces the differential differentiation of MSCs, potentially suppressing bone formation and favoring catch-up fat, which might be responsible for the increased risk of osteoporosis and obesity during CUGFR. Content Type Journal ArticlePages 1-11DOI 10.1007/s00394-011-0174-7Authors Xiangfei Guo, Department of Pain, Xuanwu Hospital, Capital Medical University, 100053 Beijing, ChinaWeihong Yang,...
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RSS Source: Med Worm - Osteoporosis Sat, 19 Feb 2011 5:59:05 am
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Osteoporosis - news item 81 of 136
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Elderly Women on Bone Drugs May Live Longer
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While bone drugs have gotten a bad rap in the media recently, experts hope mounting evidence of benefits may convince patients not to shun the medicines.Source: Reuters Health Related MedlinePlus Pages: Medicines, Osteoporosis, Seniors' Health (Source: MedlinePlus Health News)
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RSS Source: Med Worm - Osteoporosis Fri, 18 Feb 2011 9:26:50 pm
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Osteoporosis - news item 82 of 136
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Can improved obstacle avoidance performance explain the effectiveness of a multimodal falls prevention program for persons with osteoporosis? - Smulders E, Van Lankveld W, Laan R, Duysens J, Duysens J, Weerdesteyn V.
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[Abstract unavailable] Language: Eng... (Source: SafetyLit: All (Unduplicated))
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RSS Source: Med Worm - Osteoporosis Fri, 18 Feb 2011 9:06:08 pm
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Osteoporosis - news item 83 of 136
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Male idiopathic osteoporosis linked to low bone matrix mineralization
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Men with idiopathic osteoporosis have significantly reduced bone matrix mineralization, relative to normal mineralized bone, without evidence of increased bone turnover, Austrian researchers report. (Source: MedWire News - Bone Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information...
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RSS Source: Med Worm - Osteoporosis Fri, 18 Feb 2011 6:49:31 pm
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Osteoporosis - news item 84 of 136
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Relationship of body composition with prevalence of osteoporosis in central south Chinese postmenopausal women
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Conclusions  In central south Chinese postmenopausal women, both fat mass and lean mass are correlated with BMD at the lumbar spine and hip. Fat mass was the most significant determinant of BMD at the lumbar spine, while lean mass had more impact on the total hip value. Both lower values...
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RSS Source: Med Worm - Osteoporosis Fri, 18 Feb 2011 1:15:24 pm
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Osteoporosis - news item 85 of 136
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Research Midwife/Nurse and Paediatric Research Nurse (2 posts): Maternal Vitamin D Osteoporosis Study - University of Southampton
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Added via www.jobs.ac.uk Two Research Nurse positions are available to work on the MAVIDOS Maternal Vitamin D Osteoporosis Study, a trial of vitamin D supplements in pregnant women from 12 weeks to delivery. The trial will investigate the effect of vitamin D supplementation on intrauterine bone mineral accrual in the...
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RSS Source: Med Worm - Osteoporosis Fri, 18 Feb 2011 11:00:00 am
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Osteoporosis - news item 86 of 136
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Osteoporosis Drugs Linked to Lower Cancer Risk
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Title: Osteoporosis Drugs Linked to Lower Cancer RiskCategory: Health NewsCreated: 2/18/2011 11:00:00 AMLast Editorial Review: 2/18/2011 11:00:12 AM (Source: MedicineNet Chronic Pain General)
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RSS Source: Med Worm - Osteoporosis Fri, 18 Feb 2011 6:00:00 am
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Osteoporosis - news item 87 of 136
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Treatment with acetaminophen/paracetamol or ibuprofen alleviates post-dose symptoms related to intravenous infusion with zoledronic acid 5 mg
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Conclusion Oral acetaminophen/paracetamol or ibuprofen effectively managed the transient influenza-like symptoms associated with zoledronic acid 5 mg. Content Type Journal ArticlePages 1-10DOI 10.1007/s00198-011-1563-8Authors J. D. Wark, University of Melbourne Department of Medicine and Bone & Mineral Service, The Royal Melbourne Hospital, Melbourne, 3050 Victoria AustraliaW. Bensen, St. Joseph’s Hospital, McMaster...
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RSS Source: Med Worm - Osteoporosis Fri, 18 Feb 2011 5:46:57 am
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Osteoporosis - news item 88 of 136
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Important for Cancer Survivors to Follow Nutrition Advice
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Cancer survivors are at higher risk than the general population for cardiovascular disease, diabetes, and osteoporosis. Medscape Medical News (Source: Medscape Today Headlines) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
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RSS Source: Med Worm - Osteoporosis Fri, 18 Feb 2011 3:33:53 am
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Osteoporosis - news item 89 of 136
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Bisphosphonates, specific inhibitors of osteoclast function and a class of drugs for osteoporosis therapy
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AbstractOsteoporosis is a result of the disruption of bone homeostasis that is carried out by boneâ€forming osteoblasts and boneâ€degrading osteoclasts. The most common treatment of osteoporosis is Nâ€containing bisphosphonates, a class of nonâ€hydrolyzable pyrophosphate analogues. They have strong affinity to Ca2+ of hydroxyapatite with high specificity and can only be...
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RSS Source: Med Worm - Osteoporosis Thu, 17 Feb 2011 11:29:11 pm
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Osteoporosis - news item 90 of 136
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Group of enzymes could have a positive impact on health, from cholesterol to osteoporosis
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Recent studies on a group of PCSK enzymes could have a positive impact on health, from cholesterol to osteoporosis. (Source: ScienceDaily Headlines)
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RSS Source: Med Worm - Osteoporosis Thu, 17 Feb 2011 11:15:25 pm
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Osteoporosis - news item 91 of 136
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Application of the BRAFO tiered approach for benefit-risk assessment to case studies on natural foods.
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Authors: Bernhard W, Eva G, Jeljer H, Sabine K, Eva LO, Ian R, Benoît S, Jakob VK, Alessandro C There is evidence that consumption of fish, especially oily fish, has substantial beneficial effects on health. In particular an inverse relationship of oily fish intake to coronary heart disease incidence has...
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RSS Source: Med Worm - Osteoporosis Thu, 17 Feb 2011 11:00:00 pm
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Osteoporosis - news item 92 of 136
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Longitudinal Changes in Bone Mineral Density in Male Master Cyclists and Nonathletes
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This study tracked changes in bone mineral density (BMD) over a 7-year period in competitive male master cyclists (n = 19) and nonathletes (n = 18). Participants completed health/exercise history and food frequency (for calcium intake) questionnaires and underwent BMD testing by dual-energy X-ray absorptiometry. At initial and 7-year assessments, there was...
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RSS Source: Med Worm - Osteoporosis Thu, 17 Feb 2011 9:00:17 pm
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Osteoporosis - news item 93 of 136
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Hibernating bears teach scientists tricks for human hibernation
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A study of hibernating black bears paves the way for using hibernation-like states in humans for treating the critically ill and helping astronauts survive journeys through deep spaceThe black bears of Alaska spend up to seven months in hibernation every year, without eating, drinking, urinating or defecating, and when they...
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RSS Source: Med Worm - Osteoporosis Thu, 17 Feb 2011 6:00:00 pm
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Osteoporosis - news item 94 of 136
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1 Group Of Enzymes Could Have A Positive Impact On Health, From Cholesterol To Osteoporosis
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Recent studies conducted at the Institut de recherches cliniques de Montreal (IRCM) on a group of PCSK enzymes could have a positive impact on health, from cholesterol to osteoporosis. A team led by Dr. Nabil G. Seidah, Director of the Biochemical Neuroendocrinology research unit, has published six articles in prestigious...
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RSS Source: Med Worm - Osteoporosis Thu, 17 Feb 2011 8:00:00 am
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Osteoporosis - news item 95 of 136
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Australia to host IOF Regionals -- 2nd Asia-Pacific Osteoporosis and Bone Meeting
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(International Osteoporosis Foundation) IOF announces the 2nd Asia-Pacific Osteoporosis and Bone Meeting, to be held in conjunction with the Australian & New Zealand Bone & Mineral Society Annual Scientific Meeting and with the Japanese Bone and Mineral Research Society, from Sept. 4-8, 2011, in Queensland. The meeting will provide current...
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RSS Source: Med Worm - Osteoporosis Thu, 17 Feb 2011 4:00:00 am
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Osteoporosis - news item 96 of 136
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Suppression of PTH by the vitamin D analog eldecalcitol is modulated by its high affinity for the serum vitamin D binding protein and resistance to metabolism
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AbstractEldecalcitol [1α,25â€dihydroxyâ€2βâ€(3â€hydroxypropyloxy)vitamin D3], a vitamin D analog with enhanced efficacy for treatment of osteoporosis, has been found to be less potent than 1,25â€dihydroxyvitamin D3 (calcitriol) in suppressing PTH in vivo. To define the mechanism for the latter observation, we compared the effects of eldecalcitol and calcitriol on PTH secretion by...
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RSS Source: Med Worm - Osteoporosis Wed, 16 Feb 2011 11:00:00 pm
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Osteoporosis - news item 97 of 136
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High frequency of osteoporosis and fractures in women with dermatomyositis/polymyositis
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Abstract Bone mass was only previously studied in juvenile dermatomyositis/polymyositis (DM/PM) patients. Therefore, the objective this study was to evaluate the prevalence of osteoporosis and fractures in adult DM/PM. Forty female DM/PM and 78 age-, gender-, and BMI-matched healthy controls were studied. Medical charts and clinical interviews of all patients...
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RSS Source: Med Worm - Osteoporosis Wed, 16 Feb 2011 6:05:50 am
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Osteoporosis - news item 98 of 136
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Pregnancy-associated spinal osteoporosis treated with bisphosphonates: long-term follow-up of maternal and infants outcome
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Abstract Pregnancy-associated spinal osteoporosis (PPSO) is a rare condition characterized by severe back pain occurring near the end of the first pregnancy or shortly afterward. The aim of this report is to present a 12-year follow-up of a patient with PPSO. Also, the outcomes of patient’s two pregnancies and her...
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RSS Source: Med Worm - Osteoporosis Wed, 16 Feb 2011 6:05:44 am
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Osteoporosis - news item 99 of 136
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Current and future treatment options in osteoporosis
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Conclusion This review discusses the evidence supporting the use of currently available treatment options for osteoporosis and potential future advances in drug therapy. Particular consideration should be given when prescribing for certain older patients who have issues with compliance or tolerance and also in those with co-morbidities or levels of...
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RSS Source: Med Worm - Osteoporosis Wed, 16 Feb 2011 6:01:38 am
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Osteoporosis - news item 100 of 136
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Bone Health Issues in Sarcoidosis
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Abstract Sarcoidosis affects the bone directly in only a minority of patients. Nonetheless, bone health should be considered in the management of all patients with sarcoidosis. Deficiency in vitamin D, an important contributor to bone health, has been linked to autoimmune disease incidence. Studies have shown that patients with sarcoidosis...
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RSS Source: Med Worm - Osteoporosis Wed, 16 Feb 2011 6:00:03 am
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Osteoporosis - news item 101 of 136
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Osteoporosis drug, rare jaw disease link?
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PORTLAND, Ore., Feb. 16 (UPI) -- An osteoporosis drug is linked to an elevated risk of developing a rare but serious jaw disease, but the risk remains extremely low, U.S. researchers say. (Source: Health News - UPI.com) MedWorm Message: Watch the new MedWorm demo and find out how to get...
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RSS Source: Med Worm - Osteoporosis Wed, 16 Feb 2011 5:06:16 am
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Osteoporosis - news item 102 of 136
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Osteoporosis as a Risk Factor for Distal Radial Fractures: A Case-Control Study
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Conclusions: The prevalence of osteoporosis in patients with distal radial fractures is high compared with that in control subjects, and osteoporosis is a risk factor for distal radial fractures in both women and men. Thus, patients of both sexes with an age of fifty years or older who have a...
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RSS Source: Med Worm - Osteoporosis Tue, 15 Feb 2011 11:00:00 pm
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Osteoporosis - news item 103 of 136
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Osteoporosis treatment persistence poor in Sweden
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Persistence to osteoporosis treatment in Sweden is poor, with approximately half of all patients discontinuing therapy during the first year, researchers report. (Source: MedWire News - Bone Health)
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RSS Source: Med Worm - Osteoporosis Tue, 15 Feb 2011 10:28:59 pm
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Osteoporosis - news item 104 of 136
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Merck Wins Lawsuit Brought By Fosamax Patient
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From Associated Press (February 14, 2011) NEW YORK -- Merck & Co. said Monday it won a third lawsuit brought by a patient who said the company’s former blockbuster osteoporosis drug Fosamax caused dental and jaw problems. The company... (Source: Drugs.com - Pharma News)
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RSS Source: Med Worm - Osteoporosis Tue, 15 Feb 2011 1:05:06 pm
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Osteoporosis - news item 105 of 136
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Commonly Prescribed Osteoporosis Drug Associated With Very Low Risk Of Serious Jaw Disease
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A commonly prescribed osteoporosis drug is associated with a slightly elevated risk of developing the rare, but serious condition, osteonecrosis of the jaw; nonetheless the risk remains extremely low. These findings are published online in the Journal of Dental Research, the official journal of the International and American Associations for...
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RSS Source: Med Worm - Osteoporosis Tue, 15 Feb 2011 8:00:00 am
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Osteoporosis - news item 106 of 136
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Osteoporosis prevention. - Grossman JM.
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PURPOSE OF REVIEW: Patients with osteoporosis suffer from the morbidity and mortality associated with resultant fractures. The number of persons at risk for fractures is increasing as the US population ages. This review addresses preventive strategies that... (Source: SafetyLit: All (Unduplicated))
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RSS Source: Med Worm - Osteoporosis Tue, 15 Feb 2011 5:17:01 am
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Osteoporosis - news item 107 of 136
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An Educational Intervention for Providers to Promote Bone Health in Highâ€Risk Older Patients - Simone MJ, Roberts DH, Irish JT, Neeman N, Schulze JE, Lipsitz LA, Schwartzstein R, Aronson MD, Tan ZS.
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OBJECTIVES: To design, implement, and assess an educational intervention for providers focused on osteoporosis screening and management in older patients with chronic obstructive pulmonary disease or asthma who have been prescribed prolonged cou... (Source: SafetyLit: All (Unduplicated))
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RSS Source: Med Worm - Osteoporosis Tue, 15 Feb 2011 5:17:01 am
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Osteoporosis - news item 108 of 136
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Calcium supplementation in postmenopausal women to reduce the risk of osteoporotic fractures.
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Conclusion Results of recent clinical trials indicate that calcium supplementation does not significantly reduce fracture risk in postmenopausal women. However, evidence from the same studies suggests that beneficial effects on fracture risk may be seen in women who are adherent to therapy. Postmenopausal women should continue calcium supplementation to reduce...
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RSS Source: Med Worm - Osteoporosis Mon, 14 Feb 2011 11:00:00 pm
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Osteoporosis - news item 109 of 136
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A clinical trial alert tool to recruit large patient samples and assess selection bias in general practice research
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Conclusion: Although the recruitment target was unreachable for most practices, the practice staff in the participating practices used the CTA tool successfully to identify, document and survey a large patient sample. The tool also helped the research team to precisely determine a slight selection bias. (Source: BMC Medical Research Methodology...
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RSS Source: Med Worm - Osteoporosis Mon, 14 Feb 2011 11:00:00 pm
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Osteoporosis - news item 110 of 136
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Denosumab: a novel biological therapy for osteoporosis
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Aging Health , February 2011, Vol. 7, No. 1, Pages 13-43. (Source: Future Medicine: Aging Health)
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RSS Source: Med Worm - Osteoporosis Mon, 14 Feb 2011 4:36:20 pm
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Osteoporosis - news item 111 of 136
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Health Tip: Learn the Benefits of a Bone-Density Test
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It can help detect osteoporosisSource: HealthDay Related MedlinePlus Page: Osteoporosis (Source: MedlinePlus Health News)
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RSS Source: Med Worm - Osteoporosis Mon, 14 Feb 2011 11:00:00 am
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Osteoporosis - news item 112 of 136
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Sex steroids and bone health in older Chinese men
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Conclusion Chinese men with low serum estradiol levels display elevated bone loss and increased risk of fractures similar to findings in Caucasians. Content Type Journal ArticlePages 1-10DOI 10.1007/s00198-011-1552-yAuthors J. Woo, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR ChinaT. Kwok, Faculty of Medicine, The Chinese...
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RSS Source: Med Worm - Osteoporosis Mon, 14 Feb 2011 6:11:23 am
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Osteoporosis - news item 113 of 136
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Maintaining femoral bone density in adults: how many steps per day are enough?
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Conclusions Our results suggest a gender, weight, and speed sensitivity of walking interventions for osteoporosis. In persons of low BW, the necessary steps per day to maintain BMD can be substantially greater than the often-quoted 10,000 steps. Content Type Journal ArticlePages 1-8DOI 10.1007/s00198-011-1538-9Authors Katherine A. Boyer, Bone and Joint Center,...
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RSS Source: Med Worm - Osteoporosis Mon, 14 Feb 2011 6:11:21 am
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Osteoporosis - news item 114 of 136
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Fragility Fractures in Men with Idiopathic Osteoporosis Are Associated with Undermineralization of the Bone Matrix without Evidence of Increased Bone Turnover
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Abstract The pathogenesis of primary osteoporosis in younger individuals is still elusive. An important determinant of the biomechanical competence of bone is its material quality. In this retrospective study we evaluated bone material quality based on quantitative backscattered electron imaging to assess bone mineralization density distribution (BMDD) in bone biopsies...
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RSS Source: Med Worm - Osteoporosis Mon, 14 Feb 2011 6:05:16 am
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Osteoporosis - news item 115 of 136
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Vertebroplasty: benefits are more than risks in selected and evidence-based informed patients. A retrospective study of 59 cases
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In conclusion, percutaneous vertebroplasty is an effective and safe procedure for treating vertebral compression fractures in the elderly. It provides immediate pain relief and allows early mobilization, thus avoiding potentially severe complications related to persistent back pain and prolonged bed rest. When performed by experienced surgeon complication rate is low,...
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RSS Source: Med Worm - Osteoporosis Fri, 11 Feb 2011 10:50:43 am
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Osteoporosis - news item 116 of 136
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Fibula-pro-tibia in plating tibial non-unions
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Conclusion The fibula-pro-tibia plating technique is an effective variation in plating diaphyseal tibial non-unions. Content Type Journal ArticlePages 1-6DOI 10.1007/s00264-011-1211-0Authors Galal Z. Said, Department of Orthopaedic and Trauma Surgery, Assiut University Hospitals, Assiut, EgyptMohammad M. El-Sharkawi, Department of Orthopaedic and Trauma Surgery, Assiut University Hospitals, Assiut, EgyptHatem G. Said, Department...
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RSS Source: Med Worm - Osteoporosis Fri, 11 Feb 2011 10:50:03 am
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Osteoporosis - news item 117 of 136
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Influence of sagittal balance and physical ability associated with exercise on quality of life in middle-aged and elderly people
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Conclusions QOL of middle-aged and elderly subjects was related to sagittal balance and physical ability. Thus, exercises for spine, muscle, and physical ability may improve QOL in middle-aged and elderly people. Content Type Journal ArticlePages 1-8DOI 10.1007/s11657-011-0052-1Authors Shiro Imagama, Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65...
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RSS Source: Med Worm - Osteoporosis Fri, 11 Feb 2011 5:46:15 am
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Osteoporosis - news item 118 of 136
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The impact of two educational interventions on osteoporosis diagnosis and treatment after fragility fracture: a population-based randomized controlled trial
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Conclusions The educational interventions assessed in this trial were not satisfactory to increase osteoporosis diagnosis or treatment in recently fractured women to a clinically meaningful degree. Content Type Journal ArticlePages 1-10DOI 10.1007/s00198-011-1533-1Authors L. Bessette, Department of Medicine, CHUL Research Centre, Laval University, Quebec City, PQ CanadaK. S. Davison, Department of...
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RSS Source: Med Worm - Osteoporosis Fri, 11 Feb 2011 5:44:36 am
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Osteoporosis - news item 119 of 136
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Osteoporosis education program improves care for asthma patients
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Results from a US study show that an educational program designed specifically for pulmonary specialists improves adherence to osteoporosis management guidelines for patients with asthma and chronic obstructive pulmonary disease. (Source: MedWire News - Respiratory)
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 8:13:17 pm
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Osteoporosis - news item 120 of 136
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Exercise for Bone Health: Rationale and Prescription
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This review takes a close look at the benefits of exercise in the prevention of osteoporosis and in reducing fracture risk in an older population. Current Opinion in Rheumatology (Source: Medscape Rheumatology Headlines)
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 7:51:30 pm
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Osteoporosis - news item 121 of 136
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Potential and Pitfalls of Using Large Administrative Claims Data to Study the Safety of Osteoporosis Therapies
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Abstract Long-term bisphosphonate use may be associated with several rare adverse events. Such associations are not optimally evaluated in conventional randomized controlled trials due to the requirements of large numbers of patients and long-term follow-up. Alternatively, administrative claims data from various sources such as Medicare have been used. Because claims...
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 7:08:05 pm
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Osteoporosis - news item 122 of 136
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Treatment of resistant nonunion of supracondylar fractures femur by megaprosthesis
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Conclusion Megaprosthesis can be offered as a one-stage salvage procedure for difficult nonunion in distal femoral fractures associated with bone loss, osteoporosis, and secondary knee arthritis. Level of evidence IV. Content Type Journal ArticlePages 1-4DOI 10.1007/s00167-011-1416-1Authors Raju Vaishya, Department of Orthopaedics, Indraprastha Apollo Hospitals, Delhi, IndiaAjay Pal Singh, Orthopaedic Surgeon,...
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 6:55:07 pm
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Osteoporosis - news item 123 of 136
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Vivacta Initiates Development Of Point Of Care Test For Vitamin D
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Vivacta Limited, the medical diagnostics company with a revolutionary system for point-of-care testing, announces it has initiated development of a new rapid diagnostic test for measuring Vitamin D. Diagnosis of Vitamin D deficiencies and regular monitoring of Vitamin D levels and obtaining results rapidly is potentially important in improving management...
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 7:00:00 am
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Osteoporosis - news item 124 of 136
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Low calcidiol levels and risk of progression of aortic calcification
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Conclusions An increase by 10 ng/mL of calcidiol was associated with a decrease in the risk of aortic calcifications progression by 44%. This figure was even higher than that observed if we increased age by 10 years. Levels of calcidiol higher than 30 ng/mL seem to be desirable to reduce...
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 5:47:23 am
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Osteoporosis - news item 125 of 136
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Determinants of forearm strength in postmenopausal women
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Conclusions Bone strength at the UDR, as quantified by μFE, can be predicted from variables obtained by HRpQCT. Predicted bone strength declines with age with changes in UDR trabecular vBMD and cortical area, related in turn to reduced skeletal loading and sex steroid levels. The predicted bone strength formula should...
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 5:47:18 am
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Osteoporosis - news item 126 of 136
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Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys
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Conclusions Balicatib partially prevented ovariectomy-induced changes in bone mass, inhibited bone turnover at most sites, and had an unexpected stimulatory effect on periosteal bone formation. Content Type Journal ArticlePages 1-11DOI 10.1007/s00198-011-1529-xAuthors C. Jerome, Think Bone Consulting, Inc, PO Box 1611, Langley, WA 98260, USAM. Missbach, Novartis Institutes for Biomedical Research,...
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 5:47:17 am
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Osteoporosis - news item 127 of 136
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Densitometry, radiography, and histological assessment of collagen as methods to evaluate femoral bones in an experimental model of osteoporosis
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Conclusions In conclusion, histological analysis could not be quantitatively compared with the methods of bone densitometry and conventional radiography; however, all of these methods were qualitatively valid for assessing the loss of bone stemming from ovariectomy and the therapeutic effect of teriparatide in the prevention of osteoporosis. Content Type Journal...
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 5:47:16 am
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Osteoporosis - news item 128 of 136
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GRAND: the German retrospective cohort analysis on compliance and persistence and the associated risk of fractures in osteoporotic women treated with oral bisphosphonates
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Conclusions Compliance and persistence with oral bisphosphonates in German women with osteoporosis were inadequate. Better compliance and persistence can prevent fractures in these women. Content Type Journal ArticlePages 1-9DOI 10.1007/s00198-011-1535-zAuthors P. Hadji, Klinik für Gynäkologie, Gynäkologische Endokrinologie und Onkologie, Philipps-University, Marburg, GermanyV. Claus, Health Economics & Outcomes Research, IMS Health...
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RSS Source: Med Worm - Osteoporosis Thu, 10 Feb 2011 5:47:14 am
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Osteoporosis - news item 129 of 136
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Older Men's Explanatory Model for Osteoporosis.
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Authors: Solimeo SL, Weber TJ, Gold DT PURPOSE: To explore the nature of men's experiences of osteoporosis by developing an understanding of men's explanatory models.  DESIGN AND METHODS:  This descriptive study invited community-residing male osteoporosis patients aged 50+ to participate in interviews about osteoporosis. Participants were recruited from a hospital-affiliated...
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RSS Source: Med Worm - Osteoporosis Wed, 9 Feb 2011 11:00:00 pm
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Osteoporosis - news item 130 of 136
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Sbds is required for Rac2-mediated monocyte migration and signaling downstream of RANK during osteoclastogenesis
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We report that Sbds is required for in vitro and in vivo osteoclastogenesis (OCG). Sbds-null murine monocytes formed osteoclasts of reduced number and size because of impaired migration and fusion required for OCG. Phenotypically, Sbds-null mice exhibited low-turnover osteoporosis consistent with findings in SDS patients. Western blotting of Rho GTPases...
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RSS Source: Med Worm - Osteoporosis Wed, 9 Feb 2011 11:00:00 pm
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Osteoporosis - news item 131 of 136
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Bisphosphonates for Osteoporosis
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New England Journal of Medicine, Volume 364, Issue 6, Page 582-584, February 2011. (Source: New England Journal of Medicine)
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RSS Source: Med Worm - Osteoporosis Wed, 9 Feb 2011 9:00:12 pm
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Osteoporosis - news item 132 of 136
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Percutaneous Vertebroplasty in Multiple Myeloma: Prospective Long-Term Follow-Up in 106 Consecutive Patients
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Conclusion PV is a safe, effective, and long-lasting procedure for the treatment of vertebral compression pain resulting from MM. Content Type Journal ArticlePages 1-7DOI 10.1007/s00270-011-0111-4Authors Giovanni Carlo Anselmetti, Interventional Radiology Unit, Institute for Cancer Research and Treatment, 10060 Candiolo, Turin, ItalyAntonio Manca, Interventional Radiology Unit, Institute for Cancer Research and...
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RSS Source: Med Worm - Osteoporosis Wed, 9 Feb 2011 4:35:37 pm
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Osteoporosis - news item 133 of 136
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Association between Bone Mineral Density and Arterial Stiffness in Hypertensive Patients.
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In conclusion, nutritional status is an important indicator of bone mineral density in hypertensive patients. Moreover, increased arterial stiffness is associated with reduced bone mineral density in hypertensive patients. Therefore, hypertensive patients with increased arterial stiffness may have a high risk of bone fracture due to osteoporosis. PMID: 21263208 [PubMed...
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RSS Source: Med Worm - Osteoporosis Wed, 9 Feb 2011 12:45:03 am
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Osteoporosis - news item 134 of 136
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The role of glucococorticoids in the immediate vs. delayed effects of acute ethanol exposure on cytokine production in a binge drinking model.
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CONCLUSION: These results indicate that the short-term effects of acute ethanol on poly I:C-induced cytokine production are not primarily mediated by corticosterone in male or female mice. In female mice, however, corticosterone does appear to mediate the persistent effects of acute ethanol administration on poly I:C-induced IL-6 levels. Since many...
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RSS Source: Med Worm - Osteoporosis Tue, 8 Feb 2011 11:00:00 pm
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Osteoporosis - news item 135 of 136
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Good long-term adherence to osteoporosis prophylaxis decreases fracture risk but may be uncommon
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Source: Osteoporosis Int Area: News A large observational study from Sweden found that only a quarter of patients started on drugs for prophylaxis of osteoporosis were still taking them after 3 years, dropping to 14% after 4 years; however long-term use did reduce risk of fractures significantly. There is much...
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RSS Source: Med Worm - Osteoporosis Tue, 8 Feb 2011 11:00:00 pm
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Osteoporosis - news item 136 of 136
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[Original Articles] Depression and Hypothalamic-Pituitary-Adrenal Activation: A Quantitative Summary of Four Decades of Research
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Conclusions: The current study suggests that the degree of HPA hyperactivity can vary considerably across patient groups. Results are consistent with HPA hyperactivity as a link between depression and increased risk for conditions, such as diabetes, dementia, coronary heart disease, and osteoporosis. Such a link is strongest among older inpatients...
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RSS Source: Med Worm - Osteoporosis Tue, 8 Feb 2011 11:00:00 pm
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