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Thu, 15 May 2008 at 22:45:32


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Psoriasis - news item 1 of 43
Fda approves taclonex scalp(r) once daily therapy for treatment of moderate to severe scalp psoriasis
Warner Chilcott and LEO Pharma announced that the United States Food and Drug Administration (FDA) has approved the New Drug Application (NDA) for Taclonex Scalp(R) (calcipotriene 0.005% and betamethasone dipropionate 0.064%) Topical Suspension. LEO Pharma submitted the NDA for Taclonex Scalp(R) to the FDA in July 2007. Taclonex Scalp(R) is...
RSS Source:   Med Worm - Psoriasis Wed, 14 May 2008 7:00:00 am
Psoriasis - news item 2 of 43
Photomedex receives fda clearance for the xtrac(r) velocity(tm) laser
MONTGOMERYVILLE, Pa.--(HSMN NewsFeed)--PhotoMedex, Inc. (NASDAQ:PHMD ), a leader in the development of proprietary excimer laser and fiber optic systems as well as techniques directed toward dermatological applications, today announced that it has received... Devices, Dermatology, FDAPhotoMedex, XTRAC Velocity, excimer laser, psoriasis, vitiligo, dermatitis (Source: HSMN NewsFeed)
RSS Source:   Med Worm - Psoriasis Tue, 13 May 2008 10:07:10 pm
Psoriasis - news item 3 of 43
Discrepant levels of vascular endothelial growth factor in psoriasis patients treated with puva, re-puva and narrow-band uvb
Photodermatology, Photoimmunology & Photomedicine, Volume 24, Issue 3, Page 123-127, June 2008. Summary Background: Previous reports showed that serum levels of vascular endothelial growth factor (VEGF) are increased in patients with psoriasis. However, to our knowledge, no studies have evaluated the effects of PUVA, Re-PUVA and narrow-band UVB (... (Source: Photodermatology,...
RSS Source:   Med Worm - Psoriasis Tue, 13 May 2008 9:19:09 am
Psoriasis - news item 4 of 43
In a case-control analysis, use of thiazolidinediones or metformin was associated with a lower risk of developing psoriasis.
(Source: Inpharma)
RSS Source:   Med Worm - Psoriasis Mon, 12 May 2008 10:31:18 pm
Psoriasis - news item 5 of 43
Fda approves taclonex scalp - once daily therapy for treatment of moderate to severe scalp psoriasis
ST. DAVID'S, Bermuda and COPENHAGEN, Denmark, May 12, 2008 /PRNewswire-FirstCall/ -- Warner Chilcott and LEO Pharma announced today that the United States Food and Drug Administration (FDA) has approved the New Drug Application (NDA) for Taclonex... (Source: Drugs.com - New Drug Approvals)
RSS Source:   Med Worm - Psoriasis Mon, 12 May 2008 2:40:52 pm
Psoriasis - news item 6 of 43
Il-21 and tgf-β are required for differentiation of human th17 cells
IL-21 and TGF-β are required for differentiation of human TH17 cells Nature advance online publication 11 May 2008. doi:10.1038/nature07021 Authors: Li Yang, David E. Anderson, Clare Baecher-Allan, William D. Hastings, Estelle Bettelli, Mohamed Oukka, Vijay K. Kuchroo & David A. Hafler The recent discovery of CD4+ T cells characterized by...
RSS Source:   Med Worm - Psoriasis Sun, 11 May 2008 4:00:00 am
Psoriasis - news item 7 of 43
Calcipotriol plus betamethasone dipropionate scalp formulation is effective and well tolerated in the treatment of scalp psoriasis: a phase ii study
Dermatology 2008;217:107-113 (DOI:10.1159/000130425) (Source: Dermatology)
RSS Source:   Med Worm - Psoriasis Fri, 9 May 2008 11:41:21 pm
Psoriasis - news item 8 of 43
Relevance of compartmentalization of t-cell subsets for clinical improvement in psoriasis: effect of immune-targeted antipsoriatic therapies
British Journal of Dermatology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SummaryBackground Therapies targeting the T cell-mediated pathology of psoriasis have been found to achieve remarkable clinical improvement and have confirmed the crucial role of the immune system either in peripheral blood (PB) or in skin. No analyses of ... (Source: British...
RSS Source:   Med Worm - Psoriasis Fri, 9 May 2008 12:39:12 pm
Psoriasis - news item 9 of 43
Pulmonary hypertension common in psoriasis patients
As much as one-third of patients with psoriasis may have pulmonary hypertension, research suggests. (Source: MedWire News - Dermatology)
RSS Source:   Med Worm - Psoriasis Fri, 9 May 2008 12:00:00 am
Psoriasis - news item 10 of 43
Radiotherapy beneficial in palmo-plantar psoriasis
Radiotherapy achieves excellent results in patients with palmo-plantar eczema or psoriasis, say Swiss researchers who recommend a single dose of 0.5 Gy twice weekly up to a total of 4-5 Gy. (Source: MedWire News - Psoriasis)
RSS Source:   Med Worm - Psoriasis Thu, 8 May 2008 11:02:11 pm
Psoriasis - news item 11 of 43
Psoriasis linked to lichen sclerosus
Psoriasis is often seen in conjunction with lichen sclerosus in gynaecologic patients, suggesting that similar immune dysregulation underlies the two skin conditions, say Austrian researchers. (Source: MedWire News - Psoriasis)
RSS Source:   Med Worm - Psoriasis Thu, 8 May 2008 11:02:11 pm
Psoriasis - news item 12 of 43
New disease loci for psoriasis identified
Personalized Medicine , May 2008, Vol. 5, No. 3, Pages 205-207. (Source: Future Medicine: Personalized Medicine)
RSS Source:   Med Worm - Psoriasis Tue, 6 May 2008 4:22:02 pm
Psoriasis - news item 13 of 43
Immunopathogenesis of psoriatic arthritis: recent advances
Abstract  Psoriatic Arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis. The pathophysiology of PsA includes genetic, environmental and immunologic factors. Recent studies revealed the dynamic role of the immune system in the pathogenesis of the disease. Adhesion molecules, proinflammatory cytokines, angiogenic factors and metalloproteinases appear to orchestrate the inflammatory...
RSS Source:   Med Worm - Psoriasis Mon, 5 May 2008 9:03:31 pm
Psoriasis - news item 14 of 43
Unique three-year data demonstrating long-term efficacy and safety of raptiva in the treatment of psoriasis published in the british journal of dermatology
Longest continuous-treatment prospective study of a biological therapy for psoriasis GENEVA, Switzerland, May 5, 2008 - Final results of the first three-year prospective efficacy and safety study in moderate-to-severe chronic plaque... (Source: Drugs.com - Clinical Trials)
RSS Source:   Med Worm - Psoriasis Mon, 5 May 2008 5:45:29 pm
Psoriasis - news item 15 of 43
Tnf blockade recommended in hiv patients with severe psoriasis
Researchers report that etanercept treatment caused a 'dramatic' improvement in von Zumbusch pustular psoriasis in a patient with HIV infection. (Source: MedWire News - Infectious Diseases)
RSS Source:   Med Worm - Psoriasis Mon, 5 May 2008 8:41:53 am
Psoriasis - news item 16 of 43
Alterations in the desquamation-related proteolytic cleavage of corneodesmosin and other corneodesmosomal proteins in psoriatic lesional epidermis
British Journal of Dermatology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. SummaryBackground Desquamation occurs after proteolysis of corneodesmosomal proteins, including corneodesmosin (CDSN), by proteases of the kallikrein family, particularly KLK7. Impaired desquamation is one of the features of psoriasis, and psoriasis-... (Source: British Journal of Dermatology)
RSS Source:   Med Worm - Psoriasis Fri, 2 May 2008 9:19:59 am
Psoriasis - news item 17 of 43
Methotrexate useful for severe childhood psoriasis in resource-poor settings
Methotrexate therapy, if strictly monitored, is a cheap and convenient treatment for children with severe psoriasis in resource-poor countries, say Indian researchers. (Source: MedWire News - Pediatrics)
RSS Source:   Med Worm - Psoriasis Fri, 2 May 2008 9:10:30 am
Psoriasis - news item 18 of 43
Mims annual dermatology conference (<p>the ibis, earls court</p> <dt><strong>address</strong>: 47 lillie road <dt>earl's court <dt>sw6 1ud london <dt>  <dt><strong>phone:</strong> (+44) 0207 610 0880 <dt><strong>fax:</strong> (+44) 0207 3814450 <dt><strong>website</strong>: <a title=website href="http://www.ibishotel.com/"><u>http://www.ibishotel.com/</u></a> <dt>  <dt> </dt>)
MIMS Dermatology is pleased to present its second annual conference. The conference will explore your key issues around dermatology in primary care, and in particular provide practical advice and expertise in diagnosis and management of dermatological problems.Enjoy a unique combination of clinical sessions, case studies, interactive sessions and hands-on workshops to enable...
RSS Source:   Med Worm - Psoriasis Fri, 2 May 2008 9:05:37 am
Psoriasis - news item 19 of 43
Pruritus particularly common among female psoriasis patients
Pruritus is common among patients with chronic plaque psoriasis, particularly women, Swedish study findings indicate. (Source: MedWire News - Psoriasis)
RSS Source:   Med Worm - Psoriasis Fri, 2 May 2008 12:00:00 am
Psoriasis - news item 20 of 43
Facial involvement indicates severe psoriasis
Facial involvement in psoriasis is more common than generally realized, and serves as a marker of severe disease, Turkish investigators have discovered. (Source: MedWire News - Psoriasis)
RSS Source:   Med Worm - Psoriasis Fri, 2 May 2008 12:00:00 am
Psoriasis - news item 21 of 43
Alefacept effective for treating scalp psoriasis
Alefacept, an immunomodulatory biologic agent that targets T cells, is effective in treating scalp psoriasis in adults, according to a report in the April issue of the Journal of the American Academy of Dermatology. Reuters Health Information (Source: Medscape Dermatology Headlines)
RSS Source:   Med Worm - Psoriasis Thu, 1 May 2008 6:04:11 pm
Psoriasis - news item 22 of 43
Incidence and prevalence of psoriatic arthritis: a systematic review.
Related Articles Incidence and Prevalence of Psoriatic Arthritis: A Systematic Review. J Rheumatol. 2008 May 1; Authors: Alamanos Y, Voulgari PV, Drosos AA OBJECTIVE: Descriptive epidemiological studies of psoriatic arthritis (PsA) in the general population were very limited until the year 2000. Recently, several incidence and prevalence studies of PsA...
RSS Source:   Med Worm - Psoriasis Thu, 1 May 2008 4:00:00 am
Psoriasis - news item 23 of 43
Psoriasis and vascular disease: an unsolved mystery.
Psoriasis and vascular disease: an unsolved mystery. Am J Med. 2008 May;121(5):360-5 Authors: Shelling ML, Federman DG, Prodanovich S, Kirsner RS Psoriasis is an immune disease most commonly recognized for its skin and joint manifestations. These produce significant physical, social, and psychological distress in affected patients and resultant reductions in...
RSS Source:   Med Worm - Psoriasis Thu, 1 May 2008 4:00:00 am
Psoriasis - news item 24 of 43
High prevalence of concomitant anogenital lichen sclerosus and extragenital psoriasis in adult women.
High Prevalence of Concomitant Anogenital Lichen Sclerosus and Extragenital Psoriasis in Adult Women. Obstet Gynecol. 2008 May;111(5):1143-1147 Authors: Eberz B, Berghold A, Regauer S OBJECTIVE: To analyze the prevalence of lichen sclerosus and psoriasis in gynecologic patients. METHODS: The prevalence of lichen sclerosus and psoriasis individually, as well as the...
RSS Source:   Med Worm - Psoriasis Thu, 1 May 2008 4:00:00 am
Psoriasis - news item 25 of 43
Exacerbation of psoriatic skin lesions in a patient with psoriatic arthritis receiving adalimumab
Journal of Clinical Pharmacy and Therapeutics, Volume 33, Issue 3, Page 321-325, June 2008. SummaryObjective: To report a case of a patient with psoriatic arthritis (PsA) receiving adalimumab, who developed an exacerbation of palmoplantaris pustulosa psoriasis.Case summary: A 38-year-old woman diagnosed with PsA had received treatment with non-... (Source: Journal of Clinical...
RSS Source:   Med Worm - Psoriasis Wed, 30 Apr 2008 8:50:32 pm
Psoriasis - news item 26 of 43
Importance of screening for comorbidities in psoriasis patients
Psoriasis is a common complex inflammatory disease that shares many immunological features with other common complex disorders, such as cardiovascular disease, obesity, diabetes, depression and inflammatory arthritis. Expert Review of Dermatology (Source: Medscape Dermatology Headlines)
RSS Source:   Med Worm - Psoriasis Wed, 30 Apr 2008 4:21:10 pm
Psoriasis - news item 27 of 43
Differential mrna expression of antimicrobial peptides and proteins in atopic dermatitis as compared to psoriasis vulgaris and healthy skin
Int Arch Allergy Immunol 2008;147:17-24 (DOI:10.1159/000128582) (Source: International Archives of Allergy and Immunology)
RSS Source:   Med Worm - Psoriasis Wed, 30 Apr 2008 8:36:33 am
Psoriasis - news item 28 of 43
Increased frequency of pulmonary hypertension in psoriasis patients
Abstract  Several reports have demonstrated an association between psoriasis and cardiovascular diseases such as hypertension, valvular disease and arrhythmia. However, the data is scarce. Forty-seven psoriasis patients and 20 healthy people underwent transthoracic echocardiographic examination including pulse- and tissue Doppler analysis and 24-h ambulatory electrocardiographic monitoring including heart rate variability (HRV)...
RSS Source:   Med Worm - Psoriasis Wed, 30 Apr 2008 7:24:58 am
Psoriasis - news item 29 of 43
Regeneration of human epidermis on acellular dermis is impeded by small-molecule inhibitors of egf receptor tyrosine kinase
Abstract  The family of human epidermal growth factor receptors (EGFR, HER2–4) exerts key functions in normal and malignant epithelial cells. Both EGFR and HER2 are valuable targets for anti-cancer drugs by interfering with ligand binding, receptor dimerization, or tyrosine kinase activity. A similar therapeutic strategy has been advocated for chronic psoriasis...
RSS Source:   Med Worm - Psoriasis Wed, 30 Apr 2008 7:24:57 am
Psoriasis - news item 30 of 43
A high viral load of epstein-barr virus dna in ocular fluids in an hla-b27-negative acute anterior uveitis patient with psoriasis
A high viral load of Epstein-Barr virus DNA in ocular fluids in an HLA-B27-negative acute anterior uveitis patient with psoriasis Content Type Journal ArticleCategory LettersDOI 10.1007/s10384-007-0508-4Authors Hidemi Takahashi, Tokyo Medical and Dental University Graduate School of Medicine Department of Ophthalmology & Visual Science 1-5-45 Yushima, Bunkyo-ku Tokyo 113-8519 JapanSunao Sugita,...
RSS Source:   Med Worm - Psoriasis Wed, 30 Apr 2008 7:00:47 am
Psoriasis - news item 31 of 43
Ilv-094 for psoriasis
Researchers are seeking volunteer research subjects with psoriasis to evaluate the safety and tolerability of an investigational medicine for psoriasis. (Source: dukehealth.org: Duke Clinical Trials)
RSS Source:   Med Worm - Psoriasis Tue, 29 Apr 2008 7:25:24 pm
Psoriasis - news item 32 of 43
Disseminated eruptive giant mollusca contagiosa in an adult psoriasis patient during efalizumab therapy
Dermatology 2008;217:85-86 (DOI:10.1159/000128282) (Source: Dermatology)
RSS Source:   Med Worm - Psoriasis Mon, 28 Apr 2008 1:54:54 pm
Psoriasis - news item 33 of 43
Infliximab: psoriasis: case report
(Source: Reactions)
RSS Source:   Med Worm - Psoriasis Mon, 28 Apr 2008 7:25:59 am
Psoriasis - news item 34 of 43
Etanercept/infliximab: psoriasis: 3 case reports
(Source: Reactions)
RSS Source:   Med Worm - Psoriasis Mon, 28 Apr 2008 7:25:59 am
Psoriasis - news item 35 of 43
Nice final appraisal determination: adalimumab for the treatment of psoriasis
The National Institute for Health and Clinical Excellence (NICE) has published a “Final Appraisal Determination” on the use of adalimumab for the treatment of plaque psoriasis in adults. The Institute makes the following recommendations (taken directly from source): • Adalimumab is recommended as a treatment option for adults with plaque...
RSS Source:   Med Worm - Psoriasis Mon, 28 Apr 2008 12:00:00 am
Psoriasis - news item 36 of 43
[ifn-alpha-induced psoriatic arthritis and hcv-related liver cirrhosis. therapeutic options and patient's opinion.]
Related Articles [IFN-alpha-induced psoriatic arthritis and HCV-related liver cirrhosis. Therapeutic options and patient's opinion.] Reumatismo. 2008;60(1):57-60 Authors: Cauli A, Porru G, Vacca A, Mameli A, Ibba V, Mura V, Piga M, Mathieu A Hepatitis C virus (HCV) infection in the setting of Psoriatic Arthritis is an additional variable to be...
RSS Source:   Med Worm - Psoriasis Fri, 25 Apr 2008 7:54:59 pm
Psoriasis - news item 37 of 43
Photography allows accurate psoriasis assessment
It is possible to accurately and consistently assess the severity and progression of psoriasis from photographs, say French researchers. (Source: MedWire News - Psoriasis)
RSS Source:   Med Worm - Psoriasis Fri, 25 Apr 2008 11:30:49 am
Psoriasis - news item 38 of 43
Abt-874, a fully human monoclonal anti-il-12/il-23 antibody for the potential treatment of autoimmune diseases
ABT-874, a fully human mAb that blocks the binding of IL-12 and IL-23 to their shared IL-12 receptor β1, is currently being developed by Abbott Laboratories for the potential treatment of Crohn's disease and psoriasis. The compound is currently in phase III clinical trials for psoriasis and phase II trials...
RSS Source:   Med Worm - Psoriasis Fri, 25 Apr 2008 4:00:00 am
Psoriasis - news item 39 of 43
Xtoll, a recombinant chaperonin 10 as an anti-inflammatory immunomodulator
CBio Ltd, under license from the University of Queensland, is developing a recombinant form of chaperonin 10, known as XToll, for the potential anti-inflammatory treatment of rheumatoid arthritis, psoriasis and multiple sclerosis. All three indications have been evaluated in phase IIa clinical trials. By May 2005, a phase IIa trial...
RSS Source:   Med Worm - Psoriasis Fri, 25 Apr 2008 4:00:00 am
Psoriasis - news item 40 of 43
Efalizumab benefits maintained in long term
The longest study of efalizumab in psoriasis to date shows that patients continue to improve for about 18 months and maintain these improvements throughout at least 3 years of therapy. (Source: MedWire News - Psoriasis)
RSS Source:   Med Worm - Psoriasis Fri, 25 Apr 2008 12:00:00 am
Psoriasis - news item 41 of 43
Added acitretin allows reduced etanercept frequency in psoriasis
Adding acitretin to etanercept treatment allows a reduction of etanercept dosing from twice weekly to once a week without loss of efficacy, Italian researchers have discovered. (Source: MedWire News - Psoriasis)
RSS Source:   Med Worm - Psoriasis Fri, 25 Apr 2008 12:00:00 am
Psoriasis - news item 42 of 43
Patient characteristics impact biological efficacy in clinical practice
Doctors treating psoriasis patients should not expect biologicals to always be as effective in clinical practice as they are in RCTs, researchers warn. (Source: MedWire News - Psoriasis)
RSS Source:   Med Worm - Psoriasis Fri, 25 Apr 2008 12:00:00 am
Psoriasis - news item 43 of 43
Psoriasis and dilated cardiomyopathy: coincidence or associated diseases?
Cardiology 2008;111:202-206 (DOI:10.1159/000121605) (Source: Cardiology)
RSS Source:   Med Worm - Psoriasis Thu, 24 Apr 2008 11:07:03 am