Senile Dementia/Alzheimer's Disease - news item 1 of 48
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Families shed light on likely causative gene for alzheimer's
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The genetic profile of two large Georgia families with high rates of late-onset Alzheimer's disease points to a gene that may cause the disease, researchers say. (Source: ScienceDaily Headlines)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 15 May 2008 8:21:17 am
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Senile Dementia/Alzheimer's Disease - news item 2 of 48
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Alzheimer's-like brain tangles in nonhuman primates
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Scientists at the Yerkes National Primate Research Center, Emory University, have discovered the first conclusive evidence of Alzheimer's-like neurofibrillary brain tangles in an aged nonhuman primate. The unprecedented finding, described in the online issue of the Journal of Comparative Neurology, has the potential to move the scientific community one step...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 15 May 2008 3:33:02 am
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Senile Dementia/Alzheimer's Disease - news item 3 of 48
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Anti-inflammatory drugs do not improve cognitive function in older adults, study suggests
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The anti-inflammatory drugs naproxen and celecoxib do not appear to improve cognitive function in older adults with a family history of Alzheimer's disease, and naproxen may have a slightly detrimental effect, according to a new article. (Source: ScienceDaily Headlines)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 15 May 2008 3:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 4 of 48
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Ex-justice takes alzheimer's fight public
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Sandra Day O'Connor, whose husband is suffering from Alzheimer's disease, talks to Congress about what it can do to help. (Source: WDSU.com - Health)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Wed, 14 May 2008 7:17:17 pm
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Senile Dementia/Alzheimer's Disease - news item 5 of 48
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Study could aid development of improved blood pressure drugs
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Findings from a new study could aid in the development of safer and more effective blood pressure drugs, according to Loyola University Health System researchers.The results also could help researchers predict whether drugs intended for other conditions, such as Alzheimer's disease and epilepsy, would have either the detrimental effect of...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Wed, 14 May 2008 12:00:00 pm
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Senile Dementia/Alzheimer's Disease - news item 6 of 48
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Essay contest will reward caregivers with respite
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Caring Today magazine and Home Instead Senior Care have teamed up to offer the 2008 "Give a Caregiver a Break" Essay Contest. If you like to write, this could be... (Source: About Alzheimers Disease)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Wed, 14 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 7 of 48
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Multiplicity of cerebrospinal fluid functions: new challenges in health and disease
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This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics: formation rate, pressure, flow, volume, turnover rate, composition, recycling and reabsorption. Novel ways to modulate CSF formation emanate from recent analyses of choroid plexus transcription factors (E2F5), ion transporters (NaHCO3 cotransport), transport enzymes (isoforms of carbonic anhydrase), aquaporin 1...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Wed, 14 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 8 of 48
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Substrate mediated reduction of copper-amyloid-[small beta] complex in alzheimer's disease
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Victor A. Streltsov, Joseph N. Varghese (Communication from Chem. Commun.) Victor A. Streltsov, Chem. Commun., 2008, DOI: 10.1039/b803911a To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem....
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Wed, 14 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 9 of 48
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O'connor urges help for alzheimer's disease
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Associated Press May 14, 2008 WASHINGTON - Retired Justice Sandra Day O'Connor knows the daily balancing act that Alzheimer's caregivers face: When her husband could no longer stay home alone, she had to take him to work with her at the Supreme Court. (Source: PsycPORT.com)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Wed, 14 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 10 of 48
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Older brains don't benefit from painkillers: study
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Results from a large government experiment are dimming hopes that two common painkillers can prevent Alzheimer's disease or slow mental decline in older people. (Source: CTV Health)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Tue, 13 May 2008 10:42:14 pm
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Senile Dementia/Alzheimer's Disease - news item 11 of 48
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Naproxen and celecoxib do not improve cognitive function in elderly patients
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In the Alzheimer's Disease Anti-inflammatory Prevention Trial, use of naproxen or celecoxib did not improve cognitive function, and there was weak evidence for a detrimental effect of naproxen. Medscape Medical News (Source: Medscape PublicHealth Headlines)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Tue, 13 May 2008 9:00:00 pm
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Senile Dementia/Alzheimer's Disease - news item 12 of 48
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Study: older brains don't benefit from painkillers
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CHICAGO -- Results from a large government experiment are dimming hopes that two common painkillers can prevent Alzheimer's disease or slow mental decline in older people. (Source: washingtonpost.com - Health)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Tue, 13 May 2008 8:31:44 pm
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Senile Dementia/Alzheimer's Disease - news item 13 of 48
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Novel regimen through combination of memantine and tea polyphenol for neuroprotection against brain excitotoxicity
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NMDA receptors are abundant, ubiquitously distributed throughout the brain, fundamental to excitatory neurotransmission, and critical for normal CNS function. However, excessive glutamate overstimulates NMDA receptors, leading to increased intracellular calcium and excitotoxicity. Mitochondrial dysfunction associated with loss of Ca2+homeostasis and enhanced cellular oxidative stress has long been recognized to play...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Tue, 13 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 14 of 48
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[chemistry] platinum-based inhibitors of amyloid-{beta} as therapeutic agents for alzheimer's disease
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Amelyoid-β peptide (Aβ) is a major causative agent responsible for Alzheimer's disease (AD). Aβ contains a high affinity metal binding... (Source: Proceedings of the National Academy of Sciences)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Tue, 13 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 15 of 48
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The accuracy of the mmse in detecting cognitive impairment when administered by general practitioners: a prospective observational study
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Background: The Mini-Mental State Examination (MMSE) has contributed to detecting cognitive impairment, yet few studies have evaluated its accuracy when used by general practitioners (GP) in an actual public-health setting. We evaluated the accuracy of MMSE scores obtained by GPs by comparing them to scores obtained by Alzheimer's Evaluation Units (...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Tue, 13 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 16 of 48
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Study: painkillers don't slow elder mental decline
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Results from a large government experiment are dimming hopes that two common painkillers can prevent Alzheimer's disease or slow ... (Source: USATODAY.com Health)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Tue, 13 May 2008 12:03:48 am
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Senile Dementia/Alzheimer's Disease - news item 17 of 48
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Results from the adapt trial – naproxen and celecoxib not beneficial in prevention of alzheimer's disease
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Research findings from the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT) have been published early online in the Archives of Neurology, suggesting that neither celecoxib nor naproxen improves cognitive function in older adults with a family history of Alzheimer’s disease (AD). The authors note that observational studies have shown an association...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Tue, 13 May 2008 12:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 18 of 48
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How one mutation tips biochemistry to cause alzheimer's disease
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Forms of early-onset Alzheimer's disease are known to be hereditary, caused by single point mutations. Now, using sophisticated computer simulations, a team of physical chemists have shown precisely how the substitution of one amino acid for one that is very similar causes a subtle change in the shape of a...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 9:00:00 pm
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Senile Dementia/Alzheimer's Disease - news item 19 of 48
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The molecular basis of memory loss in transgenic models of alzheimer's disease
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The Molecular Basis of Memory Loss in Transgenic Models of Alzheimer's DiseasePresented by: Karen Hsiao Ashe, M.D., Ph.D., University of MinnesotaCategory: NeuroscienceAired date: 05/12/2008 (Source: Videocast - All Events)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 8:14:00 pm
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Senile Dementia/Alzheimer's Disease - news item 20 of 48
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Nsaids don't keep the brain nimble
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BALTIMORE -- Patients at risk for Alzheimer's disease may see no cognitive benefits from the nonsteroidal anti-inflammatory drugs naproxen (Aleve) and celecoxib (Celebrex), researchers found. (Source: MedPage Today Psychiatry)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 8:01:55 pm
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Senile Dementia/Alzheimer's Disease - news item 21 of 48
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Anti-inflammatory drugs do not improve cognitive function in older adults
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The anti-inflammatory drugs naproxen and celecoxib do not appear to improve cognitive function in older adults with a family history of Alzheimer's disease, and naproxen may have a slightly detrimental effect, according to an article posted online that will appear in the July 2008 print issue of Archives of Neurology,...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 8:00:00 pm
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Senile Dementia/Alzheimer's Disease - news item 22 of 48
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Mechanism uncovered of action of antibiotic able to reduce neuronal cell death in brain
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Research Highlights: Mechanism of action of compound found to induce neurotransmitter activity in brain cells The findings may lead researchers to develop potential novel therapies to treat Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, (Source: Alzheimer's / Dementia News From Medical News Today)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 10:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 23 of 48
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Study: pain relievers do not deter alzheimer's disease
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Results from a large government experiment are dimming hopes that two common painkillers can prevent Alzheimer's disease or slow mental decline in older people. (Source: FOXNews.com)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 9:39:38 am
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Senile Dementia/Alzheimer's Disease - news item 24 of 48
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Mechanism of action of antibiotic able to reduce neuronal cell death in brain uncovered
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Researchers have discovered how an antibiotic works to modulate the activity of a neurotransmitter that regulates brain functions, which eventually could lead to therapies to treat Alzheimer's disease, Huntington's disease, epilepsy, stroke, dementia and malignant gliomas. (Source: ScienceDaily Headlines)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 9:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 25 of 48
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Weight link to dementia
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"Obesity doubles the risk of Alzheimer's" is the headline in the Daily Express. It and other news sources report new research which found that people who are obese have an increased risk of all types of dementia. Being underweight "increased the risk of any kind of dementia by 36 per...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 9:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 26 of 48
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The synthetic triterpenoid cddo-methyl ester modulates microglial activities, inhibits tnf production, and provides dopaminergic neuroprotection
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Background: Recent animal and human studies implicate chronic activation of microglia in the progressive loss of CNS neurons. The inflammatory mechanisms that have neurotoxic effects and contribute to neurodegeneration need to be elucidated and specifically targeted without interfering with the neuroprotective effects of glial activities. Synthetic triterpenoid analogs of oleanolic...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 27 of 48
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Brief screening for mild cognitive impairment in elderly outpatient clinic: validation of the korean version of the montreal cognitive assessment
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The Montreal Cognitive Assessment (MoCA) is a brief cognitive screening tool with high sensitivity for screening patients with mild cognitive impairment (MCI). The authors examined the validity and reliability of the Korean version of the MoCA (MoCA-K) in elderly outpatients. The MoCA-K, a Korean version of the Mini-Mental State Examination (...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 28 of 48
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Clinical trials: cognitive function over time in the alzheimer's disease anti-inflammatory prevention trial (adapt): results of a randomized, controlled trial of naproxen and celecoxib
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Background Observational studies have shown reduced risk of Alzheimer dementia in users of nonsteroidal anti-inflammatory drugs.Objective To evaluate the effects of naproxen sodium and celecoxib on cognitive function in older adults.Design Randomized, double-masked chemoprevention trial.Setting Six US memory clinics.Participants Men and women aged 70 years and older with a family...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 29 of 48
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Model shows how mutation tips biochemistry to cause alzheimer's
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(University of North Carolina at Charlotte) Forms of early-onset Alzheimer's disease are known to be hereditary, caused by single point mutations. Now, using sophisticated computer simulations, a team of physical chemists have shown precisely how the substitution of one amino acid for one that is very similar causes a subtle...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Mon, 12 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 30 of 48
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Discovery of mechanism of action of antibiotic able to reduce neuronal cell death in brain
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Virginia Commonwealth University researchers have discovered how an antibiotic works to modulate the activity of a neurotransmitter that regulates brain functions, which eventually could lead to therapies to treat Alzheimer's disease, Huntington's disease, epilepsy, stroke, dementia and malignant gliomas. (Source: News-Medical News Feed)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Sun, 11 May 2008 10:45:55 pm
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Senile Dementia/Alzheimer's Disease - news item 31 of 48
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Happy mother's day
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This is a special day for individuals with Alzheimer's and caregivers who are also mothers. I wish you a restful, peaceful day spent with family and filled with the knowledge... (Source: About Alzheimers Disease)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Sun, 11 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 32 of 48
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Sage's health fair to include information about alzheimer's disease
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There isn't a lot of information or support for older adults with diverse sexual orientations and gender identities who are dealing with Alzheimer's disease. That's why I was so pleased... (Source: About Alzheimers Disease)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Sat, 10 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 33 of 48
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May is older americans month
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May is Older Americans Month, an opportunity to honor older members of our society for their priceless contributions to family, community, education, the arts, science, and many other areas of... (Source: About Alzheimers Disease)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Sat, 10 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 34 of 48
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More families post videos of etanercept results
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About a month ago, I posted an update on etanercept treatment of Alzheimer's that included YouTube videos of real people with the disease before and after receiving the treatment. Since... (Source: About Alzheimers Disease)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Sat, 10 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 35 of 48
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Serum magnesium level and clinical deterioration in alzheimer's disease
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Gerontology 2007;53:419-422 (DOI:10.1159/000110873) (Source: Gerontology)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Fri, 9 May 2008 11:41:28 pm
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Senile Dementia/Alzheimer's Disease - news item 36 of 48
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Court of appeal makes decision following ruling that nice process on anti-dementia medicines unfair, uk
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Eisai Limited, the licence holder of Aricept® (donepezil hydrochloride) and Pfizer Limited, its co-promotion partner, announced today that the Court of Appeal has released its decision on the consequential issues arising from Court of Appeal's recent ruling that the process by which the National Institute for Health and Clinical Excellence (...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Fri, 9 May 2008 5:00:00 pm
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Senile Dementia/Alzheimer's Disease - news item 37 of 48
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Molecules in plants may have beneficial effect on alzheimer's disease
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A set of molecules found in certain plants appears to have a beneficial effect in brain tissue associated with Alzheimer's disease, according to a new study conducted in mice. The study was led by researchers at the University of South Florida and Cedars-Sinai Medical Center. An article in the Journal...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Fri, 9 May 2008 7:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 38 of 48
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Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain
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(Virginia Commonwealth University) Virginia Commonwealth University researchers have discovered how an antibiotic works to modulate the activity of a neurotransmitter that regulates brain functions, which eventually could lead to therapies to treat Alzheimer's disease, Huntington's disease, epilepsy, stroke, dementia and malignant gliomas. (Source: EurekAlert! - Biology)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Fri, 9 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 39 of 48
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Long-term use of ibuprofen lowers alzheimer's disease risk
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Long-term use of nonsteroidal anti-inflammatory drugs, specifically ibuprofen, lowers the risk for Alzheimer's disease. Medscape Medical News (Source: Medscape Internal Medicine Headlines)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 9:00:00 pm
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Senile Dementia/Alzheimer's Disease - news item 40 of 48
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New target for alzheimer's disease identified
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In a new study, published in the Journal of Neuroscience, researchers have determined in mouse models that modulating the activity of enkephalin peptides in the brain might reduce the cognitive deficits seen in Alzheimer's disease. (Source: ScienceDaily Headlines)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 6:00:00 pm
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Senile Dementia/Alzheimer's Disease - news item 41 of 48
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Alzheimer's disease: modulating enkephalin may reduce cognitive deficits
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Alzheimer's disease (AD) is an incurable disease that is increasing in prevalence and will increase even more rapidly as the Baby Boom generation enters the age of highest risk. The available AD drugs are only partially effective in some patients. New strategies are urgently needed. (Source: Seniors / Aging News From...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 10:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 42 of 48
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Patent claims allowed covering samaritan's alzheimer's memory recovery drug in australia
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Samaritan Pharmaceuticals (OTCBB:SPHC), a biopharmaceutical company committed to commercializing new innovative therapeutic drugs, has received notification that the claims in the patent application for "Neuroprotective Spirostenol Pharmaceutical Compositions" covering Caprospinol (SP-233) have been allowed by the Australian Patent Office. The hallmark of Alzheimer's disease is plaque formation in areas of...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 9:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 43 of 48
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Obesity significantly raises dementia risk - underweight also raises risk
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Being obese can increase the risk of Alzheimer's Disease by as much as 80 percent, according to a study in the May issue of Obesity Reviews.But it's not just weight gain that poses a risk. People who are underweight also havean elevated risk of dementia, unlike people who are normal...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 8:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 44 of 48
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To avoid dementia, watch your weight
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A study published in the May 2008 issue of Obesity Reviews shows that weight matters when it comes to warding off dementia: Obese people have an 80% increased risk for Alzheimer's disease compared to those with normal weight. (Source: WebMD Health)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 5:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 45 of 48
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Novel phage peptides attenuate beta amyloid-42 catalysed hydrogen peroxide production and associated neurotoxicity.
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Related Articles Novel phage peptides attenuate beta amyloid-42 catalysed hydrogen peroxide production and associated neurotoxicity. Neurobiol Aging. 2008 May 8; Authors: Taddei K, Laws SM, Verdile G, Munns S, D'Costa K, Harvey AR, Martins IJ, Hill F, Levy E, Shaw JE, Martins RN Amyloid-beta (Abeta) peptides play a central role...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 46 of 48
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Significant effect of apoe epsilon 4 genotype on the risk of dementia in alzheimer's disease and mortality in persons with down syndrome
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Virtually all adults with Down syndrome (DS) have neuropathological manifestations of Dementia in Alzheimer's disease (DAD) but not all develop clinical psychopathology. The effect of allelic variants of Apolipoprotein (APOE) gene in development and progression of DAD and mortality in persons with DS is examined.Recruited participants with DS underwent two...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 47 of 48
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Camcog as a screening tool for diagnosis of mild cognitive impairment and dementia in a brazilian clinical sample of moderate to high education
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The CAMCOG is a brief neuropsychological battery designed to assess global cognitive function and ascertain the impairments that are required for the diagnosis of dementia. To date, the cut-off scores for mild cognitive impairment (MCI) have not been determined. Given the need for an earlier diagnosis of mild dementia, new...
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 4:00:00 am
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Senile Dementia/Alzheimer's Disease - news item 48 of 48
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Obesity increases alzheimer's risk
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OBESITY can increase the risk of Alzheimer's disease by up to 80 per cent, researchers say. (Source: Scotsman.com News - Health)
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RSS Source: Med Worm - Seniile Dementia and Alzheimer's Disease Thu, 8 May 2008 12:00:00 am
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