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Mon, 07 Mar 2011 at 20:45:58


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Testicular Cancer - news item 1 of 136
Cancer rise and sperm quality fall 'due to chemicals' (BBC News Online, 4 March 2011)
A Finnish study published in the International Journal of Andrology has shown a link between trends in sperm quality and testicular cancer between generations, and has suggested an environmental cause for the findings. Full article (Source: Society for Endocrinology)
RSS Source:   Med Worm - Testicular Cancer Fri, 4 Mar 2011 11:00:00 am
Testicular Cancer - news item 2 of 136
Cancers up as sperm quality down
Sperm quality has significantly deteriorated as rates of testicular cancer have risen, a study in Finland has found. (Source: BBC News | Health | UK Edition)
RSS Source:   Med Worm - Testicular Cancer Fri, 4 Mar 2011 8:40:27 am
Testicular Cancer - news item 3 of 136
Interdisciplinary evidence-based recommendations for the follow-up of testicular germ cell cancer patients.
This article summarizes the recommendations for follow-up of testicular cancer patients of an interdisciplinary multinational working group consisting of urologists, medical oncologists, and radiation oncologists. PMID: 21346388 [PubMed - in process] (Source: Onkologie)
RSS Source:   Med Worm - Testicular Cancer Thu, 3 Mar 2011 2:45:04 am
Testicular Cancer - news item 4 of 136
Recent adverse trends in semen quality and testis cancer incidence among Finnish men
SummaryImpaired semen quality and testicular cancer may be linked through a testicular dysgenesis syndrome of foetal origin. The incidence of testis cancer has been shown to increase among Finnish men, whereas there is no recent publication describing temporal trends in semen quality. Therefore, we carried out a prospective semen quality...
RSS Source:   Med Worm - Testicular Cancer Tue, 1 Mar 2011 11:00:00 pm
Testicular Cancer - news item 5 of 136
A Diagnostic Dilemma: Metastatic Testicular Cancer and Systemic Sarcoidosis †A Review of the Literature
Case Rep Oncol 2011;4:118†124 (DOI:10.1159/000324184) (Source: Karger Publishers) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Testicular Cancer Tue, 1 Mar 2011 4:07:56 pm
Testicular Cancer - news item 6 of 136
Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes [Cell Biology]
TAp63, but not its homolog p53, eliminates oocytes that suffered DNA damage. An equivalent gene for guarding the male germ line is currently not known. Here we identify hitherto unknown human p63 transcripts with unique 5′-ends derived from incorporated exons upstream of the currently mapped TP63 gene. These unique p63...
RSS Source:   Med Worm - Testicular Cancer Mon, 28 Feb 2011 11:00:00 pm
Testicular Cancer - news item 7 of 136
Urological cancer care pathways: development and use in the context of systematic reviews and clinical practice guidelines
Conclusion The process provides a useful framework for improving urological cancer care through evidence synthesis, research prioritisation, stakeholder involvement and international collaboration. Although the focus of this work is urological cancers, the methodology can be applied to all aspects of urology and is transferable to other clinical specialties. Content Type...
RSS Source:   Med Worm - Testicular Cancer Thu, 24 Feb 2011 4:36:54 pm
Testicular Cancer - news item 8 of 136
CT Detects Relapse of Testicular Cancer
Late computed tomography (CT) scans were able to spot significant abnormalities in patients treated for nonseminoma germ cell tumors, leading to appropriate surgery or surveillance. Medscape Medical News (Source: Medscape Med Students Headlines)
RSS Source:   Med Worm - Testicular Cancer Wed, 23 Feb 2011 8:10:10 pm
Testicular Cancer - news item 9 of 136
Screening for testicular cancer.
Authors: Ilic D, Misso ML Testicular cancer commonly affects men aged between 20 and 35 years. Screening for testicular cancer may reduce both morbidity and mortality, yet the effectiveness of any method is unknown. Equally, screening may also promote treatment procedures that are unwarranted or may adversely affect the health...
RSS Source:   Med Worm - Testicular Cancer Sat, 19 Feb 2011 1:00:09 pm
Testicular Cancer - news item 10 of 136
[AH-10/04 - international study on testicular cancer : Randomized phase III study 1xBEP in comparison to 2xBEP for patients with non-seminomatous testicular cancer in clinical stage I (high risk).]
Authors: Rexer H PMID: 21327899 [PubMed - as supplied by publisher] (Source: Der Urologe. Ausg. A)
RSS Source:   Med Worm - Testicular Cancer Thu, 17 Feb 2011 11:00:00 pm
Testicular Cancer - news item 11 of 136
Semen quality and reproductive hormone levels in men from Southern Spain
SummaryIn North European countries, a significant difference in semen quality among young men has been shown. Men from the western countries, Denmark, Germany and Norway, have lower semen quality than men from the eastern countries Finland, Estonia and Lithuania. Similarly, men in the western countries have a higher risk of...
RSS Source:   Med Worm - Testicular Cancer Thu, 17 Feb 2011 11:00:00 pm
Testicular Cancer - news item 12 of 136
Management of Seminomatous Testicular Cancer: A Binational Prospective Population-Based Study From the Swedish Norwegian Testicular Cancer Study Group [Urologic Oncology]
Conclusion An international, population-based treatment protocol for testicular seminoma is feasible with excellent results. Surveillance remains a good option for CS1 patients. No factors predicted relapse in CS1 patients on surveillance. Despite resulting in a lower rate of relapse than with adjuvant carboplatin, adjuvant radiotherapy has been abandoned in the...
RSS Source:   Med Worm - Testicular Cancer Wed, 16 Feb 2011 11:00:00 pm
Testicular Cancer - news item 13 of 136
Sexual Functioning in Male Survivors of Lymphoma: A Systematic Review
Conclusions.  Conclusions are limited by methodological issues including lack of utilization of standardized measures of sexual function and longitudinal research. Even so, there is evidence of sexual dysfunction among lymphoma survivors. Clinicians need to be sensitive to these issues. Future longitudinal work is necessary to determine the likelihood of recovery....
RSS Source:   Med Worm - Testicular Cancer Tue, 15 Feb 2011 11:00:00 pm
Testicular Cancer - news item 14 of 136
Men over 40 'have double the risk of dying from testicular cancer'
A study of 28,000 men in the U.S found men over 40 had twice the risk of dying from testicular cancer when taking treatments and economic status into account. (Source: the Mail online | Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very...
RSS Source:   Med Worm - Testicular Cancer Thu, 10 Feb 2011 1:41:47 pm
Testicular Cancer - news item 15 of 136
Testicular cancer deaths double with after 40 diagnosis
NEW YORK (Reuters) - Men diagnosed with testicular cancer at 40 years of age or older have twice the risk of dying from the disease as younger patients, according to a study of nearly 28,000 men. (Source: Reuters: Health)
RSS Source:   Med Worm - Testicular Cancer Thu, 10 Feb 2011 12:34:43 am
Testicular Cancer - news item 16 of 136
Surveillance/chemo recommended for testicular cancer
Active surveillance or chemotherapy work well for most men diagnosed with seminomatous (more) (Source: AuntMinnie.com Headlines)
RSS Source:   Med Worm - Testicular Cancer Mon, 7 Feb 2011 6:00:00 am
Testicular Cancer - news item 17 of 136
Regional variations in testicular cancer rates in Ireland: clusters and communities
Content Type Journal ArticlePages 1-2DOI 10.1007/s11845-011-0688-2Authors U. B. Fallon, Department of Public Health Medicine, HSE Dublin Mid-Leinster, Tullamore, Co. Offaly IrelandM. T. O’Mahony, Department of Public Health Medicine, HSE-S (Cork and Kerry), Cork, Ireland Journal Irish Journal of Medical ScienceOnline ISSN 1863-4362Print ISSN 0021-1265 (Source: Irish Journal of Medical Science)...
RSS Source:   Med Worm - Testicular Cancer Thu, 3 Feb 2011 6:07:58 am
Testicular Cancer - news item 18 of 136
The Surgery after… retroperitoneal lymph node dissection and surgery of the residual masses after chemotherapy for advanced testicular cancer.
Authors: Guillemin F, Betala Belinga JF, Marchal F, Rauch P, Verhaeghe JL Thirty-six cases of retroperitoneal lymph node dissections for residual mass after chemotherapy for testicular cancer are reported. In a reference center, the recruitment is modified by the severity of the situations related to very big masses, tumors of...
RSS Source:   Med Worm - Testicular Cancer Wed, 26 Jan 2011 11:00:00 pm
Testicular Cancer - news item 19 of 136
Testicular cancer: seminoma
New evidence; conclusion confirmed for: Surveillance New evidence added. Categorisation unchanged (Trade-off between benefits and harms). Different adjuvant radiotherapy regimens New evidence added. Categorisation unchanged (Beneficial). Different number of cycles of adjuvant chemotherapy New evidence added. Categorisation unchanged (Unknown effectiveness), as there remains insufficient evidence to define the optimum number...
RSS Source:   Med Worm - Testicular Cancer Tue, 25 Jan 2011 10:00:00 pm
Testicular Cancer - news item 20 of 136
Testicular cancer in patients after treatment of cryptorchidism
Conclusion The undescended testicle is the most common genital malformation in boys. When diagnosed, it should be treated as early as possible, but successful treatment appears not to lessen the risk of testicular cancer, patients must be closely monitored follow-up. Content Type Journal ArticlePages 40-42DOI 10.1007/s10330-011-0735-5Authors Tao Ma, Department of...
RSS Source:   Med Worm - Testicular Cancer Fri, 21 Jan 2011 6:54:11 am
Testicular Cancer - news item 21 of 136
Gene expression profiling of rat spermatogonia and Sertoli cells reveals signaling pathways from stem cells to niche and testicular cancer cells to surrounding stroma
Conclusions: Our data suggest that SSC and their niche specifically express complementary factors for cell communication and that the same factors might be implicated in the communication between tumor cells and their micro-enviroment in testicular cancer. (Source: BioMed Central)
RSS Source:   Med Worm - Testicular Cancer Wed, 12 Jan 2011 11:00:00 pm
Testicular Cancer - news item 22 of 136
Beyond the Abstract - Testicular cancer risk associated with occupational radiation exposure: A ...
BERKELEY, CA (UroToday.com) - We conducted a systematic literature review... (Source: UroToday)
RSS Source:   Med Worm - Testicular Cancer Tue, 11 Jan 2011 10:05:00 pm
Testicular Cancer - news item 23 of 136
Family of dead chemotherapy drug trial participant seeking justice
(NaturalNews) Twenty-seven-year-old Gary Foster of Essex, U.K., recently died after participating in a government-funded drug trial that involved multiple double-doses of toxic chemotherapy. And while his family has since received the equivalent of nearly half a million dollars as a settlement -- or perhaps hush money, depending on how you...
RSS Source:   Med Worm - Testicular Cancer Mon, 10 Jan 2011 6:00:00 am
Testicular Cancer - news item 24 of 136
Anne Vyalitsyna Gives Prostate Exam to Naked Boyfriend Adam Levine (PHOTO)
Couple Model for Prostate, Testicular Cancer Awareness (Source: Health News: CBSNews.com)
RSS Source:   Med Worm - Testicular Cancer Fri, 7 Jan 2011 2:50:15 pm
Testicular Cancer - news item 25 of 136
Cancer in first‐degree relatives and risk of testicular cancer in Denmark
AbstractFamilial aggregation of testicular cancer has been reported consistently, but it is less clear if there is any association between risk of testicular cancer and other cancers in the family. We conducted a population based case‐control study to examine the relationship between risk of testicular cancer and 22 different cancers...
RSS Source:   Med Worm - Testicular Cancer Mon, 3 Jan 2011 11:00:00 pm
Testicular Cancer - news item 26 of 136
OCT 4 immunohistochemistry in postpubertal cryptorchidism
Abstract Patients with cryptorchidism are at an increased risk for germ cell testicular cancer. OCT 4 has been shown to be a sensitive and specific marker for some types of germ cell testicular cancer. We undertook this study to establish whether OCT 4 immunohistochemistry is a useful tool in the...
RSS Source:   Med Worm - Testicular Cancer Fri, 31 Dec 2010 5:04:01 pm
Testicular Cancer - news item 27 of 136
Metastasis of colorectal carcinoma to the testes: Clinical presentation and possible pathways - ...
Department of Internal Medicine, American University of Beirut Medical Center, P.O. Box 113-6044, Beirut, 1107 2802, Lebanon. (Source: UroToday) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Testicular Cancer Thu, 23 Dec 2010 10:00:00 pm
Testicular Cancer - news item 28 of 136
Lessons learned from testicular cancer: Identification of cytoplasmic p21 as an Achilles heel of cisplatin resistance.
Authors: Koster R, Jong SD Comment on: Koster R, et al. J Clin Invest 2010; 120:3594-605; DOI:10.1172/JCI41939. PMID: 21150324 [PubMed - as supplied by publisher] (Source: Cell Cycle)
RSS Source:   Med Worm - Testicular Cancer Tue, 14 Dec 2010 11:00:00 pm
Testicular Cancer - news item 29 of 136
Spermatogonial stem cells, infertility, and testicular cancer
AbstractThe spermatogonial stem cells (SSCs) are responsible for the transmission of genetic information from an individual to the next generation. SSCs play critical roles in understanding the basic reproductive biology of gametes and treatments of human infertility. SSCs not only maintain normal spermatogenesis, but also sustain fertility by critically balancing...
RSS Source:   Med Worm - Testicular Cancer Mon, 13 Dec 2010 11:00:00 pm
Testicular Cancer - news item 30 of 136
Cancer prevention and health promotion for people with intellectual disabilities: an exploratory study of staff knowledge
Discussion  Findings of this study show that health promotion and cancer prevention activities for people with ID may be less than optimal. The importance of staff training in order to raise knowledge and awareness is highlighted. Educating both staff and people with ID about the early signs and symptoms of...
RSS Source:   Med Worm - Testicular Cancer Sun, 12 Dec 2010 11:00:00 pm
Testicular Cancer - news item 31 of 136
Is male infertility a forerunner to cancer?
CONCLUSION: The identification and examination of these common points of origin supports the integration of testicular cancer screenings into the routine evaluation of infertile men. (Source: International Braz J Urol) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information...
RSS Source:   Med Worm - Testicular Cancer Sat, 11 Dec 2010 11:02:23 pm
Testicular Cancer - news item 32 of 136
Men Worldwide Grow Mustaches for Cancer Effort
"Movember" Participants Raise More Than $60 Million for Prostate and Testicular Cancer (Source: Health News: CBSNews.com)
RSS Source:   Med Worm - Testicular Cancer Wed, 1 Dec 2010 8:59:58 pm
Testicular Cancer - news item 33 of 136
[Informations for the infertile couple].
Authors: Oger P, Nicollet B, Wainer B, de Crécy MA The aim of the first consultation related to infertility is supposed to be the optimization of all factors that can increase the chances of pregnancy: more frequent sexual intercourse during the fertility windows; lifestyle modifications (better diet, decreased exposure to...
RSS Source:   Med Worm - Testicular Cancer Tue, 30 Nov 2010 11:00:00 pm
Testicular Cancer - news item 34 of 136
Why Sir Mix-A-Lot Had It Right
In this study, he surveyed hundreds of men, across various age groups, to gather data on the body shape that men find most attractive. He discovered that the ratio of the width of a woman's natural waist to the width of her hips was significantly linked to men's ratings of...
RSS Source:   Med Worm - Testicular Cancer Tue, 30 Nov 2010 6:37:46 am
Testicular Cancer - news item 35 of 136
A systematic review and meta-analysis of perinatal variables in relation to the risk of testicular cancer--experiences of the son
Conclusion In conclusion, this systematic review and meta-analysis finds evidence that cryptorchidism, inguinal hernia and twinning, and tentative evidence that birth weight and gestational age, are associated with risk of testicular cancer. (Source: International Journal of Epidemiology) MedWorm Message: Watch the new MedWorm demo and find out how to get...
RSS Source:   Med Worm - Testicular Cancer Thu, 25 Nov 2010 11:00:00 pm
Testicular Cancer - news item 36 of 136
Determination of biological variation of α-fetoprotein and choriogonadotropin (β chain) in disease-free patients with testicular cancer
Conclusions: The estimation of BV allows us to calculate analytical goals and RCVs, necessary tools for the correct interpretation of serial measurements in the follow-up of patients. Clin Chem Lab Med 2010;48:1799†801. (Source: Clinical Chemistry and Laboratory Medicine)
RSS Source:   Med Worm - Testicular Cancer Thu, 25 Nov 2010 5:01:45 pm
Testicular Cancer - news item 37 of 136
Second to fourth digit ratios, male genital development and reproductive health: a clinical study among fertile men and testis cancer patients
In conclusion, all significant findings indicate that the human male reproductive function is negatively related to 2D : 4D. However, 2D : 4D for testicular cancer patients does not point to a hormonal imbalance during foetal life as the common cause for developing germ‐cell cancer. Such results obtained, thanks to an easy, direct and...
RSS Source:   Med Worm - Testicular Cancer Mon, 22 Nov 2010 11:00:00 pm
Testicular Cancer - news item 38 of 136
It's time to systematically investigate biomarkers for treatment allocation of testicular cancer patients
(Source: BJU International)
RSS Source:   Med Worm - Testicular Cancer Sat, 20 Nov 2010 2:15:18 pm
Testicular Cancer - news item 39 of 136
US Doctors Say Chemicals Can Cause Cancer
Dr Linda Giudice has treated thousands of patients over the years with a range of troubling reproductive disorders, and this week, she joined health experts and a young mother in fingering chemicals as the probable cause. "I have treated thousands of patients... including young men with very abnormal sperm counts...
RSS Source:   Med Worm - Testicular Cancer Fri, 19 Nov 2010 11:00:00 pm
Testicular Cancer - news item 40 of 136
Plerixafor Enables Successful Hematopoietic Stem Cell Collection in an Extensively Pretreated Patient with Testicular Cancer.
We report the case of a 26-year-old man with testicular cancer who was extensively pretreated and failed to mobilize a sufficient number of HPSCs after cytotoxic chemotherapy and the administration of G-CSF and pegylated G-CSF (PEG-G-CSF). Using a combination of plerixafor, G-CSF and PEG-G-GSF after chemotherapy, a sufficient number of...
RSS Source:   Med Worm - Testicular Cancer Fri, 19 Nov 2010 11:00:00 pm
Testicular Cancer - news item 41 of 136
Regional variations in testicular cancer rates in Ireland
Conclusions There is a higher incidence rate of TCa in Cork than any other county. High rates of cryptorchidism alone cannot explain this. There appears to be a link with higher socio-economic status and possibly industrial pollutants. The association between sedentary lifestyle and the development of TCa is unproven. Content...
RSS Source:   Med Worm - Testicular Cancer Fri, 19 Nov 2010 6:38:23 am
Testicular Cancer - news item 42 of 136
Identification of Autoantibodies in a Patient With Testicular Cancer and Concurrent Inflammatory Bowel Disease [DIAGNOSIS IN ONCOLOGY]
(No abstract is available for this citation) (Source: Journal of Clinical Oncology)
RSS Source:   Med Worm - Testicular Cancer Wed, 17 Nov 2010 11:00:00 pm
Testicular Cancer - news item 43 of 136
DGU 2010 - Treatment of testicular intraepithelial neoplasia (TIN): Results of a multicenter ...
DUSSELDORF, GERMANY (UroToday.com) - One hundred sixty-nine patients with testicular cancer from 42 clinics (84 patients with seminoma and... (Source: UroToday) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Testicular Cancer Mon, 15 Nov 2010 10:04:00 pm
Testicular Cancer - news item 44 of 136
Men's Knowledge of Testicular Cancer May Be Rising
Compared to a few decades ago, men may be more aware of issues surrounding testis cancer, including symptoms and cure rates, and may be more likely to perform self-examination, according to research published in the October issue of Urology. (Source: Modern Medicine)
RSS Source:   Med Worm - Testicular Cancer Thu, 11 Nov 2010 11:00:00 pm
Testicular Cancer - news item 45 of 136
Testosterone deficiency in testicular germ‐cell cancer patients is not influenced by oncological treatment
In conclusion, TD rates are high in testis cancer patients. This is present at primary diagnosis and most likely related to testicular dysgenesis or atrophy. Our longitudinal evaluation indicates that treatment modalities have minor influence and effect on the persistently high rates of TD in TGCC patients. (Source: International Journal...
RSS Source:   Med Worm - Testicular Cancer Wed, 10 Nov 2010 5:41:43 pm
Testicular Cancer - news item 46 of 136
Testosterone deficiency in testicular germ-cell cancer patients is not influenced by oncological treatment.
In conclusion, TD rates are high in testis cancer patients. This is present at primary diagnosis and most likely related to testicular dysgenesis or atrophy. Our longitudinal evaluation indicates that treatment modalities have minor influence and effect on the persistently high rates of TD in TGCC patients. PMID: 21062302 [PubMed...
RSS Source:   Med Worm - Testicular Cancer Mon, 8 Nov 2010 11:00:00 pm
Testicular Cancer - news item 47 of 136
Retroperitoneal Lymph Node Dissection for Residual Masses after Chemotherapy in Nonseminomatous Germ Cell Testicular Tumor
Conclusion: PC-RPLND is a relatively safe procedure. The presence of fibrosis and large residual masses are associated with surgical complications and non-nerve-sparing procedure. (Source: World Journal of Surgical Oncology)
RSS Source:   Med Worm - Testicular Cancer Mon, 8 Nov 2010 11:00:00 pm
Testicular Cancer - news item 48 of 136
Mild Painkillers During Pregnancy Linked To Reproductive Health Problems In Boys
New research from Europe found that women who took a combination of more than one type of mild painkiller like paracetamol, aspirin and ibuprofen, during pregnancy, or who took at least one of these during the second trimester, were more likely to have sons with cryptorchidism, commonly known as undescended...
RSS Source:   Med Worm - Testicular Cancer Mon, 8 Nov 2010 6:00:00 pm
Testicular Cancer - news item 49 of 136
Characterization and Functionality of Proliferative Human Sertoli Cells.
Authors: Chui K, Trivedi A, Cheng CY, Cherbavaz DB, Dazin PF, Huynh AL, Mitchell JB, Rabinovich GA, Noble-Haeusslein LJ, John CM It has long been thought that mammalian Sertoli cells are terminally differentiated and non-dividing post-puberty. For most previous in vitro studies immature rodent testes have been the source of...
RSS Source:   Med Worm - Testicular Cancer Thu, 4 Nov 2010 11:00:00 pm
Testicular Cancer - news item 50 of 136
A prospective study of neuropsychological functioning in testicular cancer patients.
CONCLUSION: No negative effect of systemic chemotherapy on neuropsychological test performance in TCPs at 1-year follow-up was found in this study. PMID: 21048038 [PubMed - as supplied by publisher] (Source: Ann Oncol)
RSS Source:   Med Worm - Testicular Cancer Tue, 2 Nov 2010 11:00:00 pm
Testicular Cancer - news item 51 of 136
Clinical Prognostic Markers of Non-seminomatous Germ Cell Tumours: An Insight from Swedish Family-cancer Database
Testicular cancers are predominantly germ cell tumors (GCTs) of 2 main types, seminomas and nonseminomas. However, about one half of GCTs contain multiple histologic types and the remainder contains a single histologic type. Mixed seminoma/nonseminoma is usually treated as nonseminoma in clinical studies, because the nonseminomatous part plays the most...
RSS Source:   Med Worm - Testicular Cancer Sun, 31 Oct 2010 11:00:00 pm
Testicular Cancer - news item 52 of 136
Her-2/Neu Expression in Testicular Cancer†A Retrospective Analysis in 57 Cases
Conclusions: The analysis of her-2/neu expression in primary testicular cancer is of no therapeutic relevance. However, for the future we will explore the expression of her-2/neu in residual masses after chemotherapy to assess the role of targeted therapy in chemoresistant metastases. (Source: Urology) MedWorm Message: Watch the new MedWorm demo...
RSS Source:   Med Worm - Testicular Cancer Sun, 31 Oct 2010 11:00:00 pm
Testicular Cancer - news item 53 of 136
Role of 14-3-3sigma in poor prognosis and in radiation and drug resistance of human pancreatic cancers
Conclusion: The increased level of 14-3-3sigma protein likely contributes to the poor clinical outcome of human pancreatic cancers by causing resistance to radiation and anticancer drugs. Thus, 14-3-3sigma may serve as a prognosis marker predicting survival of pancreatic cancer patients and, thus, guide the clinical treatment of these patients. (Source:...
RSS Source:   Med Worm - Testicular Cancer Sun, 31 Oct 2010 11:00:00 pm
Testicular Cancer - news item 54 of 136
How the inventor of the pill changed the world for women
Scientist Carl Djerassi made his discovery 60 years ago †and set the ball rolling for a series of monumental changesAmong certain people †Catholics, moralists, social conservatives †the urge to make Carl Djerassi regret his invention seems to be overpowering. He brought us the pill. The more you...
RSS Source:   Med Worm - Testicular Cancer Fri, 29 Oct 2010 10:01:20 pm
Testicular Cancer - news item 55 of 136
Testicular cancer and height
Conclusion This study suggests that taller men may have a greater risk of developing testicular cancer. But it is not clear why this should be the case, or if height and cancer risk are both associated with some other factor (such as diet), which has a role to play in...
RSS Source:   Med Worm - Testicular Cancer Thu, 28 Oct 2010 3:03:00 pm
Testicular Cancer - news item 56 of 136
Height Might Affect Risk Of Testicular Cancer
Taller men could be at an increased risk of testicular cancer, new research suggests. The study, published in the British Journal of Cancer, claimed that for every extra two inches (or 5 centimetres) in height the risk of testicular cancer could increase by 13 per cent. The lifetime risk of...
RSS Source:   Med Worm - Testicular Cancer Thu, 28 Oct 2010 9:00:00 am
Testicular Cancer - news item 57 of 136
Testicular cancer: Tall men 'more likely' to develop disease
An analysis of studies involving thousands of men, found that every extra two inches in height raises the odds of developing the disease by 13 per cent. (Source: the Mail online | Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant,...
RSS Source:   Med Worm - Testicular Cancer Wed, 27 Oct 2010 10:16:53 am
Testicular Cancer - news item 58 of 136
Tall men at (slightly) higher risk of cancer
WALKING tall can increase a man's chances of developing testicular cancer, a study suggests. (Source: Scotsman.com News - Health)
RSS Source:   Med Worm - Testicular Cancer Tue, 26 Oct 2010 10:39:35 pm
Testicular Cancer - news item 59 of 136
Tall men risk testicular cancer
Taller men appear to be at increased risk of testicular cancer, US experts discover, after surveying data on 10,000 men. (Source: BBC News | Health | UK Edition)
RSS Source:   Med Worm - Testicular Cancer Tue, 26 Oct 2010 10:34:52 pm
Testicular Cancer - news item 60 of 136
Taller men 'more likely to develop testicular cancer'
Taller men are more at risk from testicular cancer, new research suggests. (Source: Telegraph Health)
RSS Source:   Med Worm - Testicular Cancer Tue, 26 Oct 2010 1:23:46 pm
Testicular Cancer - news item 61 of 136
Assessing the Accuracy of Scrotal Ultrasound in Diagnosing Testicular Malignancy in a Single Teaching Hospital Over a 5 Year Period
Scrotal ultrasound is accepted as a minimally invasive, inexpensive test for the investigation of scrotal pathology, examining not only the affected testicle, but also the contra lateral testicle. We aim to assess whether scrotal ultrasound performed for suspected malignancy in our institution correlates with pathological findings following orchidectomy and review...
RSS Source:   Med Worm - Testicular Cancer Tue, 26 Oct 2010 6:49:47 am
Testicular Cancer - news item 62 of 136
Environmental Impacts on Reproductive Health and Fertility
These editors present convincing evidence that 60 years of declining reproductive performance in both men and women is related to increases in over 87,000 commercial and natural occurring environmental chemicals. Since the early 1940s, there has been a dramatic increase in human exposure to toxic substances in air, water, soil,...
RSS Source:   Med Worm - Testicular Cancer Wed, 20 Oct 2010 11:00:00 pm
Testicular Cancer - news item 63 of 136
ASCO 2010 - Role of primary retroperitoneal lymph node dissection (RPLND) in clinical stage 1 ...
CHICAGO, IL USA - Presented by David P. Wood, Jr., MD at the 2010 Annual Meeting of the American... (Source: UroToday)
RSS Source:   Med Worm - Testicular Cancer Mon, 18 Oct 2010 10:04:00 pm
Testicular Cancer - news item 64 of 136
Cardiovascular Risk Factors and Morbidity in Long-Term Survivors of Testicular Cancer: A 20-Year Follow-Up Study [Urologic Oncology]
Conclusion Treatment with infradiaphragmatic RT and/or cisplatin-based chemotherapy, particularly the BEP regimen, increases the long-term risk for CVD in survivors of TC. (Source: Journal of Clinical Oncology)
RSS Source:   Med Worm - Testicular Cancer Sun, 17 Oct 2010 10:00:00 pm
Testicular Cancer - news item 65 of 136
Androgen substitution with testosterone undecanoate in survivors of bilateral testicular cancer ...
Department of Oncology, National Resource Center for Late Effects, Department of Oncology, Oslo University Hospital and University of Oslo, Norway. (Source: UroToday)
RSS Source:   Med Worm - Testicular Cancer Thu, 14 Oct 2010 10:00:00 pm
Testicular Cancer - news item 66 of 136
Testicular Cancer Therapy Raises Long-Term Risk for Cardiovascular Disease
Testicular cancer survivors who were treated with chemotherapy, radiotherapy or both have increased long-term risks for cardiovascular disease, a new study found. Reuters Health Information (Source: Medscape Medical News Headlines)
RSS Source:   Med Worm - Testicular Cancer Mon, 4 Oct 2010 4:56:00 pm
Testicular Cancer - news item 67 of 136
What is new in cryptorchidism and hypospadias†a critical review on the testicular dysgenesis hypothesis
Abstract: It has been hypothesized that poor semen quality, testis cancer, undescended testis, and hypospadias are symptoms of one underlying entity†the testicular dysgenesis syndrome†leading to increasing male fertility impairment. Though testicular cancer has increased in many Western countries during the past 40 years, hypospadias rates have not changed...
RSS Source:   Med Worm - Testicular Cancer Thu, 30 Sep 2010 10:00:00 pm
Testicular Cancer - news item 68 of 136
αvβ3 imaging can accurately distinguish between mature teratoma and necrosis in 18F-FDG-negative residual masses after treatment of non-seminomatous testicular cancer: a preclinical study
Conclusion Imaging αvβ3 integrin accurately distinguished mature teratoma from necrosis following cisplatin-based treatment in human NSGCT xenografts. Content Type Journal ArticleDOI 10.1007/s00259-010-1624-9Authors Nicolas Aide, Bioticla Team, EA1772, IFR 146 ICORE, GRECAN, François Baclesse Cancer Centre and Caen University, Caen, FranceMélanie Briand, Bioticla Team, EA1772, IFR 146 ICORE, GRECAN, François Baclesse...
RSS Source:   Med Worm - Testicular Cancer Thu, 30 Sep 2010 7:16:08 am
Testicular Cancer - news item 69 of 136
Comic Books Featuring 'Super Heroes' Educate Young Men About Testicular Cancer
Comic books may help to educate young men and their partners about testicular cancer and its early symptoms and encourage them to do more self-screening, according to Ryerson University School of Fashion professor and comic book artist David Brame. Brame is the lead author of the study, Ain't Nothing Comic...
RSS Source:   Med Worm - Testicular Cancer Fri, 24 Sep 2010 11:00:00 am
Testicular Cancer - news item 70 of 136
[Cryptorchidism: From physiopathology to infertility.]
Authors: Robin G, Boitrelle F, Marcelli F, Colin P, Leroy-Martin B, Mitchell V, Dewailly D, Rigot JM Cryptorchidism is a defect of testicular descent. Hormonal, genetic and environmental factors might also contribute to the aetiology of cryptorchidism and its increased incidence in recent years in industrialised countries. Cryptorchidism itself might...
RSS Source:   Med Worm - Testicular Cancer Thu, 23 Sep 2010 10:00:00 pm
Testicular Cancer - news item 71 of 136
Cytotoxic Testicular Cancer Treatment May Raise CVD Risk
Men who receive chemotherapy, radiotherapy, or a combination of the two as treatment for testicular cancer may be at increased long-term risk for cardiovascular disease, according to research published online Sept. 20 in the Journal of Clinical Oncology. (Source: Modern Medicine)
RSS Source:   Med Worm - Testicular Cancer Thu, 23 Sep 2010 10:00:00 pm
Testicular Cancer - news item 72 of 136
Study Weighs Against Tests for Testicular Cancer (CME/CE)
(MedPage Today) -- A review of studies emphasizing the pros and cons of testicular cancer screening helped reaffirm a 2004 U.S. Preventive Services Task Force recommendation against early screening -- while yielding little new information. (Source: MedPage Today Hematology/Oncology) MedWorm Message: Watch the new MedWorm demo and find out how...
RSS Source:   Med Worm - Testicular Cancer Tue, 21 Sep 2010 7:25:19 pm
Testicular Cancer - news item 73 of 136
Routine Screening Not Recommended for Testicular Cancer
There is no new evidence to support changing current recommendations against routine screening in asymptomatic men. Medscape Medical News (Source: Medscape Medical News Headlines)
RSS Source:   Med Worm - Testicular Cancer Tue, 21 Sep 2010 5:07:29 am
Testicular Cancer - news item 74 of 136
Testicular Cancer Screening in Asymptomatic Men Not Needed
No new evidence has emerged warranting a change in the U.S. Preventive Services Task Force's 2004 conclusion that screening asymptomatic men for testicular cancer is unlikely to offer benefits over clinical detection, according to a literature review in the Sept. 21 issue of the Annals of Internal Medicine. (Source: Modern...
RSS Source:   Med Worm - Testicular Cancer Mon, 20 Sep 2010 10:00:00 pm
Testicular Cancer - news item 75 of 136
Ejaculatory Status and Fertility Rates After Primary Retroperitoneal Lymph Node Dissection
Conclusions: Most men who undergo modern primary retroperitoneal lymph node dissection maintain antegrade emission and ejaculation. (Source: The Journal of Urology)
RSS Source:   Med Worm - Testicular Cancer Sun, 19 Sep 2010 10:00:00 pm
Testicular Cancer - news item 76 of 136
p73 participates in male germ cells apoptosis induced by etoposide
Etoposide is a commonly used drug in testicular cancer chemotherapy. However, the molecular pathways that activate germ cell apoptosis in response to etoposide are poorly understood. The aim of this study was to evaluate the participation of p73, a member of the p53 family, in apoptosis induced by etoposide in...
RSS Source:   Med Worm - Testicular Cancer Wed, 15 Sep 2010 3:07:59 pm
Testicular Cancer - news item 77 of 136
Imatinib/interferon-: First report of testicular cancer: case report
(Source: Reactions) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Testicular Cancer Mon, 13 Sep 2010 4:57:44 am
Testicular Cancer - news item 78 of 136
Arterial occlusion precipitated by cisplatin-based chemotherapy
Cisplatin-based therapy is curative in testicular cancer. Adverse effects of cisplatin-based chemotherapy include dose-dependent myelosuppression, nephrotoxicity, neurotoxicity, and ototoxicity. By contrast, chemotherapy-associated vascular complications are unpredictable. Few incidents of digital gangrene with cisplatin have been reported. Here, we present a patient who developed arterial occlusion leading to gangrene of the...
RSS Source:   Med Worm - Testicular Cancer Sun, 12 Sep 2010 1:19:48 pm
Testicular Cancer - news item 79 of 136
C-reactive protein; a potential marker of second cancer and cardiovascular disease in testicular cancer survivors?
Abstract: Introduction: C-reactive protein (CRP) is a marker of cardiovascular disease (CVD). There is conflicting evidence regarding CRP as a marker of future cancer. We studied whether CRP predicts CVD and consecutive cancer in testicular cancer survivors (TCSs).Patients and methods: During 1998†2001, 586 TCSs with a high sensitivity CRP...
RSS Source:   Med Worm - Testicular Cancer Thu, 9 Sep 2010 11:00:00 pm
Testicular Cancer - news item 80 of 136
Genitourinary Cancer Predisposition Syndromes
Despite epidemiologic data supporting a significant genetic contribution to the cause of genitourinary malignancies, their diagnosis rarely results in clinical genetics referral and the heritability of prostate, bladder, kidney, and testicular cancer remains poorly understood. Little of this inheritance has been explained by rare, high-penetrance predisposition syndromes and, although rare...
RSS Source:   Med Worm - Testicular Cancer Tue, 7 Sep 2010 4:10:59 am
Testicular Cancer - news item 81 of 136
Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells
Authors: K Almstrup, J E Nielsen, O Mlynarska, M T Jansen, A Jørgensen, N E Skakkebæk & E Rajpert-De Meyts (Source: British Journal of Cancer AOP)
RSS Source:   Med Worm - Testicular Cancer Mon, 6 Sep 2010 10:00:00 pm
Testicular Cancer - news item 82 of 136
Study links DDT exposure in the womb to testicular cancer
Men exposed in the womb to the pesticide dichlorodiphenyltrichloroethane (DDT) and its related compounds are more likely to develop testicular cancer, say researchers from Child Health and Development Studies (CHDS), Berkeley, CA. (Source: Modern Medicine) MedWorm Message: Watch the new MedWorm demo and find out how to get all the...
RSS Source:   Med Worm - Testicular Cancer Sat, 4 Sep 2010 10:00:00 pm
Testicular Cancer - news item 83 of 136
Androgen substitution with testosterone undecanoate in survivors of bilateral testicular cancer requires individually‐adjusted injection intervals
(Source: BJU International)
RSS Source:   Med Worm - Testicular Cancer Sat, 4 Sep 2010 6:49:24 am
Testicular Cancer - news item 84 of 136
Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer
Platinum-based chemotherapies such as cisplatin are used as first-line treatment for many cancers. Although there is often a high initial responsiveness, the majority of patients eventually relapse with platinum-resistant disease. For example, a subset of testicular cancer patients still die even though testicular cancer is considered a paradigm of cisplatin-sensitive...
RSS Source:   Med Worm - Testicular Cancer Fri, 3 Sep 2010 8:00:27 am
Testicular Cancer - news item 85 of 136
Serum tumor markers in testicular cancer.
Authors: Ehrlich Y, Beck SD, Foster RS, Bihrle R, Einhorn LH Testicular cancer has become a model for a curable neoplasm, where biochemical markers play a critical role. Serum tumor markers are integral in patient management and contributes to the diagnosis, staging, and risk assessment, as well as evaluation of...
RSS Source:   Med Worm - Testicular Cancer Thu, 2 Sep 2010 10:00:00 pm
Testicular Cancer - news item 86 of 136
JCI online early table of contents: Sept. 1, 2010
(Journal of Clinical Investigation) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Sept. 1, 2010, in the JCI: "Protecting nerve cells from death in a model of stroke"; "Modified adenovirus malaria vaccine works a treat in mice"; "Mechanisms of...
RSS Source:   Med Worm - Testicular Cancer Wed, 1 Sep 2010 3:00:00 am
Testicular Cancer - news item 87 of 136
Male reproductive tract abnormalities: More common after assisted reproduction?
We examined the association between these AR methods and developmental abnormalities of the genital tract (hypospadias, cryptorchidism), after controlling for potential confounding factors, such as prematurity, low birthweight and twinning.Results: Preterm birth and low birthweight are risk factors for hypospadias and cryptorchidism (p (Source: Early Human Development) MedWorm Message: Watch...
RSS Source:   Med Worm - Testicular Cancer Tue, 31 Aug 2010 10:00:00 pm
Testicular Cancer - news item 88 of 136
Testicular cancer risk associated with occupational radiation exposure: a systematic literature review
Author(s): Lamya Yousif, Maria Blettner, Gael P Hammer and Hajo ZeebAffiliation(s): Department of Epidemiology, Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg--University Mainz, Obere Zahlbacher Strasse 69, 55131 Mainz, Germany; Bremen Institute for Prevention Research and Social Medicine, University of Bremen, Linzer Strasse 10, 28359...
RSS Source:   Med Worm - Testicular Cancer Thu, 26 Aug 2010 10:00:00 pm
Testicular Cancer - news item 89 of 136
Testicular cancer risk associated with occupational radiation exposure: a systematic literature review.
Authors: Yousif L, Blettner M, Hammer GP, Zeeb H Testicular cancer is a rare disease, affecting mainly young men aged 15-49. There have been some recent reports that it might be associated with radiation exposure. We have systematically reviewed this topic. English-language articles published between 1990 and 2008 studying the...
RSS Source:   Med Worm - Testicular Cancer Thu, 26 Aug 2010 10:00:00 pm
Testicular Cancer - news item 90 of 136
Metabolic Syndrome After Hormone-Modifying Therapy: Risks Associated With Antineoplastic Therapy
The incidence of metabolic syndrome is rapidly increasing. Metabolic syndrome is associated with elevated morbidity and mortality secondary to cardiovascular disease, insulin resistance, and hepatic dysfunction. A body of evidence has already implicated metabolic syndrome as a cancer risk factor; emerging evidence now suggests that cancer survivors themselves may be...
RSS Source:   Med Worm - Testicular Cancer Tue, 24 Aug 2010 11:00:00 am
Testicular Cancer - news item 91 of 136
'A no means no'--measuring depression using a single-item question versus Hospital Anxiety and Depression Scale (HADS-D)
Conclusion: In a population of men with a prevalence of depression similar to that of the normal population, almost none of those responding ‘No’ to the written question ‘Are you depressed?’ were depressed according to HADS-D ≥11. Adding the category ‘I don't know’ increases sensitivity in detecting depression. (Source: Annals...
RSS Source:   Med Worm - Testicular Cancer Sat, 21 Aug 2010 6:43:01 am
Testicular Cancer - news item 92 of 136
Long-term follow-up after risk-adapted treatment in clinical stage 1 (CS1) nonseminomatous germ-cell testicular cancer (NSGCT) implementing adjuvant CVB chemotherapy. A SWENOTECA study
Conclusions: There was no statistical difference in relapse rate between one course of adjuvant CVB and surveillance for VASC– NSGCT patients. Two courses of adjuvant CVB for VASC+ NSGCT patients reduced the relapse rate with >90% in comparison to the surveillance group. Toxicity was unacceptably high for all patients receiving...
RSS Source:   Med Worm - Testicular Cancer Sat, 21 Aug 2010 6:43:01 am
Testicular Cancer - news item 93 of 136
DDT Exposure Linked to Testicular Cancer
In utero exposure to DDT and its metabolites might increase the risk for testicular cancer in male offspring. Medscape Medical News (Source: Medscape Today Headlines)
RSS Source:   Med Worm - Testicular Cancer Fri, 20 Aug 2010 4:20:26 pm
Testicular Cancer - news item 94 of 136
Prenatal DDT Exposure Tied to Testicular Cancer Risk
In the early postpartum period, maternal serum DDT-related compounds appear to be associated with sons' risk of testicular cancer three decades later, according to a study in the July issue of the Archives of Environmental & Occupational Health. (Source: Modern Medicine)
RSS Source:   Med Worm - Testicular Cancer Thu, 19 Aug 2010 10:00:00 pm
Testicular Cancer - news item 95 of 136
Are The Seeds Of Testicular Cancer Sown Before Birth? New Technique Opens Door To Further Study
Scientists at the Medical Research Council (MRC) have developed a new method to investigate how human testes develop in baby boys before they are born. MRC researchers obtained ethical approval to take testicular tissue from fetuses donated after termination. This tissue was then grafted into mice and cells developed normally,...
RSS Source:   Med Worm - Testicular Cancer Mon, 16 Aug 2010 10:00:00 am
Testicular Cancer - news item 96 of 136
Common Scrotal and Testicular Problems.
This article focuses on scrotal pain and palpable abnormalities. Scrotal pain includes well-defined acute causes such as torsion and infection and the less well-defined chronic orchialgia. Palpable abnormalities covered here include cryptorchidism, hydrocele, spermatocele, varicocele, and testicular cancer. PMID: 20705202 [PubMed - as supplied by publisher] (Source: Primary Care)
RSS Source:   Med Worm - Testicular Cancer Mon, 16 Aug 2010 2:00:55 am
Testicular Cancer - news item 97 of 136
Sonography better to monitor small testicular lesions
There is a lack of scientific evidence about the risk of testicular cancer associated with testicular lesions, but the conventional treatment approach has been immediate surgical removal because of the possibility of malignancy. A more conservative approach has served one Canadian institution well when it comes to active surveillance of...
RSS Source:   Med Worm - Testicular Cancer Tue, 10 Aug 2010 11:00:00 am
Testicular Cancer - news item 98 of 136
Scientists develop the first model for investigating the origins of testicular cancer in humans
Scientists have developed a model that will enable them to investigate, for the first time, how human testes develop in baby boys while they are in the womb. Until now it has been impossible to study testicular development during pregnancy in humans and this discovery will enable researchers to understand...
RSS Source:   Med Worm - Testicular Cancer Thu, 5 Aug 2010 8:00:00 pm
Testicular Cancer - news item 99 of 136
Testicular cancer diagnosis breakthrough
A new way of diagnosing testicular cancer has been formulated, by looking at growth in the womb, according to scientists in the UK (Source: Nursing in Practice)
RSS Source:   Med Worm - Testicular Cancer Thu, 5 Aug 2010 5:27:44 am
Testicular Cancer - news item 100 of 136
[Undescended Testis : Aspects of treatment.]
Authors: Körner I, Rübben H Undescended testis (UDT) is the most frequent congenital malformation affecting 1% of 1-year-old mature birth boys. If untreated UDT leads to progressive histological changes with impaired spermatogenesis and an increasing risk of testicular cancer. For clinical reasons palpable testes should be differentiated from impalpable testes....
RSS Source:   Med Worm - Testicular Cancer Wed, 4 Aug 2010 10:00:00 pm
Testicular Cancer - news item 101 of 136
Testis Model May Reveal Causes of Testicular Cancer
U.K. scientists hope their new xenograft model of human fetal testis tissue will shed light on the fetal origins of testicular germ cell tumors and infertility. Reuters Health Information (Source: Medscape Medical News Headlines)
RSS Source:   Med Worm - Testicular Cancer Wed, 4 Aug 2010 3:13:39 pm
Testicular Cancer - news item 102 of 136
Chemical link to testicular cancer probed (BBC News Online, 4 August 2010)
A team at the Medical Research Council's Human Reproductive Sciences Unit at Edinburgh has developed a model to study the early development of human testicular tissue, intending to use this model to first investigate whether prenatal exposure to phthalates is a cause of testicular cancer. Full article (Source: Society for...
RSS Source:   Med Worm - Testicular Cancer Wed, 4 Aug 2010 11:00:00 am
Testicular Cancer - news item 103 of 136
The First Model For Investigating The Origins Of Testicular Cancer In Humans
Scientists have developed a model that will enable them to investigate, for the first time, how human testes develop in baby boys while they are in the womb. Until now it has been impossible to study testicular development during pregnancy in humans and this discovery will enable researchers to understand...
RSS Source:   Med Worm - Testicular Cancer Wed, 4 Aug 2010 10:00:00 am
Testicular Cancer - news item 104 of 136
Chemical 'link' to cancer probed
Experts hope to prove whether common environmental chemicals, such as those used to make plastics, are to blame for rising testicular cancer rates. (Source: BBC News | Health | UK Edition)
RSS Source:   Med Worm - Testicular Cancer Wed, 4 Aug 2010 1:05:23 am
Testicular Cancer - news item 105 of 136
Edinburgh cancer study breakthrough
City scientists have made a breakthrough in studying testicular cancer in young men. (Source: Scotsman.com News - Health) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Testicular Cancer Tue, 3 Aug 2010 11:00:00 pm
Testicular Cancer - news item 106 of 136
Scots experts hail boost to research into male cancer
SCOTTISH scientists have made a breakthrough in the search for the causes of testicular cancer in young men. (Source: Scotsman.com News - Health)
RSS Source:   Med Worm - Testicular Cancer Tue, 3 Aug 2010 10:36:56 pm
Testicular Cancer - news item 107 of 136
Mice key to testicular cancer research success
Scientists have made a breakthrough in studying the origins of testicular cancer by grafting human tissue into mice. They have been able to study the development of the cells, which can cause testicular germ cell cancer (TGCC), the most common cancer among men aged 15 to 44. (Source: The Independent...
RSS Source:   Med Worm - Testicular Cancer Tue, 3 Aug 2010 10:00:01 pm
Testicular Cancer - news item 108 of 136
Testicular Cancer Survivorship: Research Strategies and Recommendations
Testicular cancer represents the most curable solid tumor, with a 10-year survival rate of more than 95%. Given the young average age at diagnosis, it is estimated that effective treatment approaches, in particular, platinum-based chemotherapy, have resulted in an average gain of several decades of life. This success, however, is...
RSS Source:   Med Worm - Testicular Cancer Tue, 3 Aug 2010 7:02:42 pm
Testicular Cancer - news item 109 of 136
Long-term Neurologic And Peripheral Vascular Toxicity After Chemotherapy Treatment Of Testicular Cancer
UroToday.com - Using modern platinum based chemotherapy, testicular cancer is a highly curable malignancy. The majority of men are diagnosed and treated in their second and third decades, and therefore persisting morbidity arising as a direct consequence of their treatment is of great concern. However hospital based follow-up is primarily...
RSS Source:   Med Worm - Testicular Cancer Tue, 3 Aug 2010 6:00:00 am
Testicular Cancer - news item 110 of 136
Testicular cancer developed in a chronic myeloid leukemia patient with a continued complete cytogenetic and molecular response to imatinib. A case report and review of the literature
Imatinib mesylate has revolutionized the treatment of chronic myeloid leukemia (CML), providing an excellent disease control and showing a satisfactory tolerance . However, due to a relatively short period of about 10 years of the clinical experience with this drug, a possible contribution of imatinib to the development of secondary neoplasms...
RSS Source:   Med Worm - Testicular Cancer Tue, 3 Aug 2010 5:52:48 am
Testicular Cancer - news item 111 of 136
Retrospective review of the outcome of post‐chemotherapy retroperitoneal lymph node dissection in the management of metastatic testicular cancer: Local experience
Objective:  (Source: Surgical Practice)
RSS Source:   Med Worm - Testicular Cancer Sat, 31 Jul 2010 10:00:00 pm
Testicular Cancer - news item 112 of 136
After Complete Remission of Testicular Cancer, What Next?
For patients with testicular cancer in complete remission, is a postchemotherapy retroperitoneal lymph node dissection needed? Dr. Howard Hochster reports on a study that answers this question. Medscape Hematology-Oncology (Source: Medscape Today Headlines)
RSS Source:   Med Worm - Testicular Cancer Fri, 30 Jul 2010 5:05:06 pm
Testicular Cancer - news item 113 of 136
Myocardial infarction and other major vascular events during chemotherapy for testicular cancer
Conclusions: There is a small but definite risk of major early CVE associated with chemotherapy of TGCC. Physicians caring for TGCC patients must be aware of this hazard. (Source: Annals of Oncology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant,...
RSS Source:   Med Worm - Testicular Cancer Wed, 28 Jul 2010 1:46:52 pm
Testicular Cancer - news item 114 of 136
Fertility in patients treated for testicular cancer - Abstract
Department for Medical Oncology, Institute of Oncology Ljubljana, Zaloska 2, 1000, Ljubljana, Slovenia. (Source: UroToday)
RSS Source:   Med Worm - Testicular Cancer Sun, 25 Jul 2010 10:00:00 pm
Testicular Cancer - news item 115 of 136
Testicular cancer survivorship: Research strategies and recommendations - Abstract
Department of Radiation Oncology and Department of Community and Preventive Medicine, University of Rochester Medical Center, Rochester, NY. (Source: UroToday)
RSS Source:   Med Worm - Testicular Cancer Thu, 22 Jul 2010 10:00:00 pm
Testicular Cancer - news item 116 of 136
The probability of surviving nine types of cancer is analyzed
(FECYT - Spanish Foundation for Science and Technology) Spanish epidemiologists have presented information on survival of nine types of cancer in Spain and have compared it with other European countries. At five years from diagnosis, the lowest survival rate is observed in lung cancer (less than 11 percent), and the...
RSS Source:   Med Worm - Testicular Cancer Thu, 15 Jul 2010 3:00:00 am
Testicular Cancer - news item 117 of 136
Testicular microlithiasis predicts concurrent testicular germ cell tumors and intratubular germ ...
Department of Medical Oncology, National Cancer Center Singapore, Republic of Singapore. (Source: UroToday)
RSS Source:   Med Worm - Testicular Cancer Sun, 4 Jul 2010 10:00:00 pm
Testicular Cancer - news item 118 of 136
Fertility in patients treated for testicular cancer
Conclusion Fertility rate after treatment for testicular cancer is reduced. From our data, the most important treatment modality that influences fertility is non nerve sparing RPLND that should be avoided whenever possible in order improve the quality of life our patients. Content Type Journal ArticleDOI 10.1007/s11764-010-0135-9Authors Erika Matos, Institute of...
RSS Source:   Med Worm - Testicular Cancer Sun, 4 Jul 2010 9:50:58 pm
Testicular Cancer - news item 119 of 136
Novel compounds with antiangiogenic and antiproliferative potency for growth control of ...
Department of Physiology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Arnimallee 22, Berlin 14195, Germany. (Source: UroToday)
RSS Source:   Med Worm - Testicular Cancer Thu, 1 Jul 2010 10:00:00 pm
Testicular Cancer - news item 120 of 136
Simultaneously detected bilateral testicular cancer of different histopathological origin--a challenging situation for the urologist.
CONCLUSIONS: Due to improved diagnostic tools as well as the establishment of various adjuvant treatment options, the mortality of testicular cancer generally decreased in the last decades. However, metastatic bilateral testicular cancer of different histology is a challenging situation for the urologist, which warrants further discussion. Adjuvant treatment as well...
RSS Source:   Med Worm - Testicular Cancer Wed, 30 Jun 2010 10:00:00 pm
Testicular Cancer - news item 121 of 136
Prenatal DDT Exposure and Testicular Cancer: A Nested Case-Control Study.
Authors: Cohn BA, Cirillo PM, Christianson RE The authors examined maternal serum levels of DDT-related compounds in relation to son's risk of testicular cancer 30 years later. Fifteen of 9,744 live-born sons were diagnosed with germ cell testicular cancer and had maternal serum samples. Cases were matched to three controls...
RSS Source:   Med Worm - Testicular Cancer Wed, 30 Jun 2010 10:00:00 pm
Testicular Cancer - news item 122 of 136
Inconstancy of human sex ratios at birth
To the Editor: When human sex ratio (proportion male) at birth is categorized by some demographic variables (e.g., maternal age, paternal age, parity) it is, as confirmed by Ein-Mor et al. , “remarkably constant.” However, I have adduced evidence that sex ratio shows substantial variation when it is categorized by selected other...
RSS Source:   Med Worm - Testicular Cancer Wed, 30 Jun 2010 10:00:00 pm
Testicular Cancer - news item 123 of 136
Clinical Inquiries: How useful are genital exams during boys' sports physicals?
Authors: Khodaee M, Housner JA, Tweed EM Examination may be useful to identify hernia but not testicular cancer. Insufficient evidence exists to recommend for or against screening genital exams for boys playing sports. Given the low risk of harm, screening for hernias as a part of a preparticipation physical evaluation (...
RSS Source:   Med Worm - Testicular Cancer Wed, 30 Jun 2010 10:00:00 pm
Testicular Cancer - news item 124 of 136
Simultaneous bilateral spontaneous pneumothorax following high-dose chemotherapy and bone marrow transplantation for mantle cell lymphoma without evidence of pulmonary disease
We present a case of SBSP developing in a patient 11 days after a high-dose chemotherapy preparative regimen and stem cell transplantation without underlying pulmonary disease or evidence of lung lesions. It is important to recognize spontaneous pneumothorax as a potential complication of high-dose chemotherapy, especially in patients with known...
RSS Source:   Med Worm - Testicular Cancer Tue, 29 Jun 2010 3:31:58 pm
Testicular Cancer - news item 125 of 136
Fertility preservation medicine: Options for young adults and children with cancer - Abstract
Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institute Karolinska University Hospital Huddinge Fertility Unit,... (Source: UroToday)
RSS Source:   Med Worm - Testicular Cancer Mon, 28 Jun 2010 10:00:00 pm
Testicular Cancer - news item 126 of 136
Testicular sparing surgery for small masses - Abstract
Departments of Urology, Assaf Harofeh Medical Center, Zerifin, Israel. (Source: UroToday)
RSS Source:   Med Worm - Testicular Cancer Wed, 23 Jun 2010 10:00:00 pm
Testicular Cancer - news item 127 of 136
A controlled study of risk factors for disease and current problems in long-term testicular cancer survivors
Conclusions Several risk factors for preventive clinical interventions and current problems that eventually should be treated were identified in TCSs. Implications for cancer survivors TCSs show several risk factors and current problems that are relevant for visits to general practitioners, poorer self-rated health, and poorer QoL. These should get attention...
RSS Source:   Med Worm - Testicular Cancer Wed, 23 Jun 2010 7:11:57 pm
Testicular Cancer - news item 128 of 136
Second cancers after testicular cancer diagnosed after 1980 in Sweden
Conclusions: Of the selective affected second tumors, it will be important to confirm the association of bladder cancer with nonseminoma treatment. (Source: Annals of Oncology) MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
RSS Source:   Med Worm - Testicular Cancer Wed, 23 Jun 2010 2:25:15 pm
Testicular Cancer - news item 129 of 136
Fertility among testicular cancer survivors: a case-control study in the U.S.
Discussion While expressing greater fertility distress, higher likelihood of fertility testing, and difficulty fathering children, these data suggest that TGCT survivors are no less likely to father children than are other men. It is possible that treatment for TGCT does not permanently affect fertility or, alternatively, that TGCT survivors attempt...
RSS Source:   Med Worm - Testicular Cancer Wed, 23 Jun 2010 7:23:22 am
Testicular Cancer - news item 130 of 136
Paul Roemer’s e-patient story: Cancer, who’s in charge here?
“I learned I had testicular cancer way back in the dark ages of medicine†1985. I learned about it while on a consulting engagement in Amarillo, Texas. The entire project team was at a colleague’s apartment having dinner. The local news channel was running a short piece on how to...
RSS Source:   Med Worm - Testicular Cancer Tue, 22 Jun 2010 9:32:27 am
Testicular Cancer - news item 131 of 136
Years of Potential Life Lost and Productivity Losses From Male Urogenital Cancer Deaths†United States, 2004
Conclusions: Urogenital cancers impose a considerable health and economic burden in terms of premature deaths and productivity losses in men in the United States, particularly among the elderly and non-Hispanic whites and blacks. (Source: Urology)
RSS Source:   Med Worm - Testicular Cancer Mon, 21 Jun 2010 10:00:00 pm
Testicular Cancer - news item 132 of 136
Public Perceptions Of The Harms And Benefits Of Testicular Cancer Education: A Qualitative Study
UroToday.com - Regular testicular self-examination (TSE) is frequently promoted within testicular cancer (TC) public education materials as a means to detect cancer early. As yet there is no evidence demonstrating the clinical benefit of TSE practise and in an era of evidence-based medicine this has led to criticism over its...
RSS Source:   Med Worm - Testicular Cancer Mon, 21 Jun 2010 12:00:00 pm
Testicular Cancer - news item 133 of 136
ASCO issues guideline to improve germ cell tumor marker use
The American Society of Clinical Oncology has issued a guideline for the use of serum markers in the diagnosis, treatment, and management of germ cell tumors in men, most commonly testicular cancer. (Source: Modern Medicine) MedWorm Message: Watch the new MedWorm demo and find out how to get all the...
RSS Source:   Med Worm - Testicular Cancer Sat, 19 Jun 2010 4:53:49 am
Testicular Cancer - news item 134 of 136
Retrospective review of the outcome of post-chemotherapy retroperitoneal lymph node dissection in the management of metastatic testicular cancer: Local experience
Conclusion: This local series confirmed the survival benefit and association of minimal long-term morbidity with post-chemotherapy RPLND. (Source: Surgical Practice)
RSS Source:   Med Worm - Testicular Cancer Wed, 16 Jun 2010 10:00:00 pm
Testicular Cancer - news item 135 of 136
Scientists Identify Three New Genetic Variants That Increase Testicular Cancer Risk
A study led by The Institute of Cancer Research (ICR) has identified three new genetic risk factors for testicular cancer. The findings, published online today in Nature Genetics, come during the Everyman Male Cancer Awareness Month , which aims to increase awareness and funding for vital research into testicular and prostate...
RSS Source:   Med Worm - Testicular Cancer Mon, 14 Jun 2010 10:00:00 am
Testicular Cancer - news item 136 of 136
Scientists find genes linked to testicular cancer
LONDON (Reuters) - British scientists have found three new genetic risk factors for testicular cancer, the most common form of the disease in young men, and say their findings should aid efforts for better treatments and earlier diagnosis. (Source: Reuters: Health)
RSS Source:   Med Worm - Testicular Cancer Sun, 13 Jun 2010 4:08:20 pm